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Shear-Dependent Platelet Aggregation: Mechanisms and Therapeutic Opportunities

Frontiers
Recent studies have emphasized the importance of shear forces generated from blood flow, that primarily drive platelet activation and aggregation in thrombosis.
6 months ago

How to Spot the Signs of Codependency

Verywell Mind
Codependency in a relationship is when each person involved is mentally, emotionally, physically, and/or spiritually reliant on the other.
7 months ago

A low-rank method for parameter-dependent fluid-structure interaction discretizations with hyperelasticity

Wiley Online Library
In this paper, we propose a new method that extends this framework to nonlinear parameter-dependent fluid-structure interaction problems by means of the Newton...
4 months ago

Wheat Germination Is Dependent on Plant Target of Rapamycin Signaling

Frontiers
Our data show that rapamycin inhibits germination of wheat seeds and of their isolated embryos in a dose-dependent manner.
6 months ago

Alumni group seeks change in Cornell Code, university's definition of Antisemitism

The Ithaca Journal
A group of Cornell alumni have prompted the Ivy to change its code of conduct following antisemitic threats on its campus.
13 months ago

Defining the effects of traffic-related air pollution on the human plasma proteome using an aptamer proteomic array: A dose-dependent increase in atherosclerosis-related proteins

ScienceDirect.com
Human controlled exposure to inhaled diesel exhaust (DE), at a range of PM2.5 concentrations representative of diverse exposure settings.
35 months ago

Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects | Neuropsychopharmacology

Nature
Growing interest has been seen in using lysergic acid diethylamide (LSD) in psychiatric research and therapy. However, no modern studies...
51 months ago

Pulmonary Toxicity of Boron Nitride Nanomaterials Is Aspect Ratio Dependent

ACS Publications
We investigated the pulmonary impact and clearance of two-dimensional hexagonal boron nitride (h-BN) nanosheets and boron nitride nanotubes (BNNTs) in mice.
13 months ago

Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERBβ

Science | AAAS
We show that heme binding remodels the thermodynamic interaction profile of NCoR receptor interaction domain (RID) binding to REV-ERBβ ligand-binding domain (...
47 months ago

Tirzepatide, a dual GIP/GLP-1 receptor co-agonist for the treatment of type 2 diabetes with unmatched effectiveness regrading glycaemic control and body weight reduction

BioMed Central
Tirzepatide is the first dual GIP/GLP-1 receptor co-agonist approved for the treatment of type 2 diabetes in the USA, Europe, and the UAE.
28 months ago