WO2011064164A1 - Nebulizer - Google Patents
Nebulizer Download PDFInfo
- Publication number
- WO2011064164A1 WO2011064164A1 PCT/EP2010/067902 EP2010067902W WO2011064164A1 WO 2011064164 A1 WO2011064164 A1 WO 2011064164A1 EP 2010067902 W EP2010067902 W EP 2010067902W WO 2011064164 A1 WO2011064164 A1 WO 2011064164A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nebulizer
- container
- housing part
- counter device
- operations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
- A61M15/0036—Piercing means hollow piercing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
- A61M15/0071—Mechanical counters having a display or indicator
- A61M15/0073—Mechanical counters having a display or indicator on a ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0081—Locking means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/27—General characteristics of the apparatus preventing use
- A61M2205/276—General characteristics of the apparatus preventing use preventing unwanted use
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/109—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring
Definitions
- the container is pre-installed in nebulizer in the delivery state.
- the pre-installed container is held by a transportation lock unmovable within the housing in the delivery state in order to avoid any undesired opening of the container.
- the nebulizer Before being used for the first time the nebulizer is completely closed.
- the pre-installed container is opened by a delivery tube piercing a sealing and a septum to fluidically connect to the inner bag of the container. Further, the transportation lock is opened so that the container can move inside the nebulizer back and forth.
- Object of the present invention is to provide a nebulizer which can be used only with a predefined number of replaceable containers wherein a simple construction is possible and/or a defined handling is achieved.
- the present invention relates to a nebulizer which can be opened for inserting and replacing a container with the fluid to be nebulized.
- the nebulizer comprises a counter device for counting operations of the nebulizer.
- the counter device blocks opening of the nebulizer until a predetermined number of operations has been reached or exceeded. Thus, it can be prevented that the nebulizer is opened before the container has been (sufficiently) used or has been emptied. Thus, potential soiling of the nebulizer can be minimized and/or a defined handling can be secured.
- Fig. 2 a schematic section, rotated through 90° compared with Fig. 1, of the known nebulizer in a tensioned state;
- Fig. 4 a schematic section of the nebulizer according to Fig. 3 in an activated, tensioned state with the completely closed housing and with the opened container;
- Fig. 5 a schematic section of the nebulizer according to Fig. 4 in a non- tensioned state
- Fig. 6 a schematic section of a nebulizer with a partly closed housing and with a securing means in a housing part holding unmoveably a container in the nebulizer;
- Fig. 1 1 a perspective view of a control ring of the counter device
- Fig. 12 a perspective view of a control element of the counter device
- Fig. 13 a partial sectional view of the nebulizer without housing part, counter device and container;
- Figs. 1 and 2 show a known nebulizer 1 for atomizing a fluid 2, particularly a highly effective pharmaceutical composition or the like, diagrammatically shown in a non-tensioned state (Fig. 1) and in a tensioned state (Fig. 2).
- the nebulizer 1 is constructed in particular as a portable inhaler and preferably operates only mechanical and/or without propellant gas.
- the nebulizer 1 comprises preferably a pressure generator 5 for conveying and nebulizing the fluid 2, particularly in a preset and optionally adjustable dosage amount.
- the pressure generator 5 comprises preferably a holder 6 for the container 3, an associated drive spring 7, only partly shown, a locking element
- a conveying element such as a conveying tube 9, a non-return valve 10, a pressure chamber 1 1 and/or an nozzle 12 for nebulizing the fluid 2 into a mouthpiece 13.
- the container 3 is fixed or held in the nebulizer 1 via the holder 6 such that the conveying tube 9 penetrates into the container 3.
- the holder 6 may be constructed so that the container 3 can be exchanged.
- the housing part 18 can be rotated relative to the upper housing part 16, carrying with it the part 17b of the inner part 17.
- the drive spring 7 is tensioned in the axial direction by means of a gear or transmission (not shown) acting on the holder 6.
- the container 3 is moved axially downwards until the container 3 assumes an end position as shown in Fig. 2.
- the drive spring 7 is under tension.
- the container 3 is moved back into its original position (non-tensioned position or state shown in Fig. 1) by the drive spring 7.
- the container 3 executes a lifting or stroke movement during the tensioning process and during the atomizing process.
- the housing part 18 preferably forms a cap-like lower housing part and fits around or over a lower free end portion of the container 3.
- an aeration means such as an axially acting spring 20 arranged in the housing part 18, comes in contact with base 21 of the container 3 and pierces the container 3 or a base seal thereon with a piercing element 22 when the container 3 makes contact with it for the first time, to allow air in or aeration.
- the container 3 has been pre-installed, i.e. inserted into the nebulizer 1.
- the container 3 or its fluid outlet 24 is not yet opened.
- the second closure 26 is already opened, but not the first closure 25.
- the housing of the nebulizer 1 is closed only partly, i.e. not completely, in the delivery state, preferably by not completely closing or pushing on the housing part 18 in the shown embodiment.
- the housing part 18 is snapped on or inserted only partly in the delivery state.
- the securing member 30 is at least substantially hollow and/or cylindrical and is disposed axially between the (lower) housing part 18 and the upper housing part 16. To activate the nebulizer 1 or prepare its for use, i.e. to push the housing part 18 fully on in the axial direction and thereby open the container 3, the securing member 30 first has to be removed or released or opened.
- the securing member 30 is constructed in the manner of a banderole or the like, made of plastics, for example, and/or can be manually opened, removed or destroyed.
- the securing member 30 may alternatively or simultaneously form or constitute a seal of origin.
- other embodiments of the securing member 30 are also possible, e.g. in the form of a security tag or the like.
- the securing means 35 or base 38 comprises or holds the piercing element 22 for piercing the container 3, i.e. opening the container base 21 or its venting hole 34 in the activated and tensioned state, i.e. when the container 3 reaches its lower end position.
- the piercing element 22 is formed by a respective bending of a spring portion 39 of the securing means 35 or its base 38.
- the spring portion 39 can support or facilitate the (complete or final) connection of the container 3 to holder 6.
- the container end or edge 41 is caught between end portions 36a and 37a of the elements 36 and 37.
- the holding elements 36 grip or extend over the edge 41 and the locking elements 37 or its end portions 37a grip or extend under the edge 41 or container base 21 so that the edge 41 and container 3 are securely held preventing any axial movement of the container 3 relative to the securing means 35 and relative to the associated housing part 18 in this state, i.e. with locked securing means 35 / transportation lock 29.
- the end portions 36a of the holding elements 36 end in a first radial plane and the end portions 37a of the locking elements 37 end in another, second radial plane, wherein the two planes are axially offset to hold the edge 41 in between and/or wherein the second plane is located axially between the first plane and the lower end position of the container 3 or the lower end of the housing part 18 or the piercing element 22.
- the end portions 36a end on another radius (outer radius) than end portions 37a and/or axially spaced.
- the end portions 36a and/or 37a preferably form like claws or the like and/or extend preferably radially inwardly.
- the counter device 44 blocks opening of the nebulizer 1 until a predetermined number of operations has been reached or exceeded.
- the counter device 44 is associated to preferably only one container 3 and counts operations of the nebulizer 1 with the respective container 3, i.e. counts (only) the number of doses of fluid 2 removed or still removeable from this container 3.
- the counter device 44 blocks opening of the nebulizer 1 until a predetermined number of doses of the fluid 2 has been drawn or removed from the respective container 3.
- the counter device 44 counts the operations or uses of the respective container 3 in the nebulizer 1 and blocks opening of the nebulizer 1 until a predetermined number has been reached or exceeded.
- the counter device 44 comprises preferably a control element 50 which is shown in Fig. 10 and in a perspective view in Fig. 12.
- the control element 50 is preferably associated to the control means or control ring 45.
- the control element 50 comprises a biasing portion 51 , an engagement portion 52 and/or a locking portion 53.
- the control element 50 is axially moveable and/or guided by the housing part 18.
- the locking spring 58 is mounted in a pre- tensioned state such that it can radially expand and engage into a radial recess or the like when the locking spring 58 or part thereof is actuated or axially shifted (here by the rider 56 or its actuation portion 57) to lock the nebulizer 1 or interlock its parts 16 and 17.
- the locking spring 58 or part thereof is actuated or axially shifted (here by the rider 56 or its actuation portion 57) to lock the nebulizer 1 or interlock its parts 16 and 17.
- other constructional solutions are possible as well.
- the rider 56, the locking spring 58, the upper housing part 16, the lower housing part 18 and the control element 50 are not shown in Fig. 14.
- the inner toothing 46 is preferably axially open to enable an axial connection and disconnection with the associated drive gear 60 as shown in Fig. 14.
- the nebulizer 1 When the housing of the nebulizer 1 is completely closed, i.e. the lower housing part 18 is completely pushed on the inner part 17, the nebulizer 1, in particular the locking member 61 , interlocks preferably automatically with the lower housing part 18, the counter device 44 or its control ring 45.
- This can be achieved in that the locking member 61 flexes radially, in particular inwardly due to the interaction of a respectively inclined guiding surface 62 with the control ring 45 or ridge 49.
- the locking member 61 has passed the control ring 45 or ridge 49, it can flex back and grip under the control ring 45 or ridge 49 so that the nebulizer 1 or its housing is blocked against opening (this state is also called blocking state or secured state).
- the interlocking of the housing part 18 with the nebulizer 1 is preferably released or unblocked when CCB is reached or activated or vice versa.
- control element 50 or its engagement portion 52 blocks the control ring 45 against further rotation, because the engagement portion 52 engages into the control recess 52 in the blocking position of the control element 50.
- the monitoring device 23 does not lock the nebulizer 1 against further use. Therefore, the nebulizer 1 can be used with multiple container 3, e.g. 2, 3, 4 or 5 containers 3, one after the other until the LSB value is reached or exceeded and the nebulizer 1 is locked against further use.
- the counter device 44 can display or indicate the number of operations or uses of the nebulizer 1 with the respective container 3 already performed or still possible.
- the control ring 45 is preferably molded and/or made of plastics.
Abstract
Description
Claims
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10781681.1A EP2504052B1 (en) | 2009-11-25 | 2010-11-22 | Nebulizer |
UAA201207260A UA107097C2 (en) | 2009-11-25 | 2010-11-22 | Dispenser |
AU2010323220A AU2010323220B2 (en) | 2009-11-25 | 2010-11-22 | Nebulizer |
AP2012006207A AP3141A (en) | 2009-11-25 | 2010-11-22 | Nebulizer |
CA2781792A CA2781792C (en) | 2009-11-25 | 2010-11-22 | Nebulizer |
SG2012038410A SG181050A1 (en) | 2009-11-25 | 2010-11-22 | Nebulizer |
KR1020127016237A KR101782306B1 (en) | 2009-11-25 | 2010-11-22 | Nebulizer |
JP2012540382A JP5715640B2 (en) | 2009-11-25 | 2010-11-22 | Nebulizer |
MX2012005961A MX2012005961A (en) | 2009-11-25 | 2010-11-22 | Nebulizer. |
CN201080052884.5A CN102686260B (en) | 2009-11-25 | 2010-11-22 | Nebulizer |
EA201200775A EA026241B1 (en) | 2009-11-25 | 2010-11-22 | Nebulizer |
NZ599295A NZ599295A (en) | 2009-11-25 | 2010-11-22 | Nebulizer |
BR112012012475-7A BR112012012475B1 (en) | 2009-11-25 | 2010-11-22 | NEBULIZER |
IL219088A IL219088A (en) | 2009-11-25 | 2012-04-05 | Nebulizer |
ZA2012/02598A ZA201202598B (en) | 2009-11-25 | 2012-04-11 | Nebulizer |
MA34875A MA33755B1 (en) | 2009-11-25 | 2012-05-16 | Sprayer |
TNP2012000245A TN2012000245A1 (en) | 2009-11-25 | 2012-05-21 | Nebulizer |
HK13102847.6A HK1175418A1 (en) | 2009-11-25 | 2013-03-07 | Nebulizer |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09014680.4 | 2009-11-25 | ||
EP09014680 | 2009-11-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2011064164A1 true WO2011064164A1 (en) | 2011-06-03 |
Family
ID=43838122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2010/067902 WO2011064164A1 (en) | 2009-11-25 | 2010-11-22 | Nebulizer |
Country Status (27)
Country | Link |
---|---|
US (1) | US9724482B2 (en) |
EP (1) | EP2504052B1 (en) |
JP (1) | JP5715640B2 (en) |
KR (1) | KR101782306B1 (en) |
CN (2) | CN104225735B (en) |
AP (1) | AP3141A (en) |
AR (1) | AR079154A1 (en) |
AU (1) | AU2010323220B2 (en) |
BR (1) | BR112012012475B1 (en) |
CA (1) | CA2781792C (en) |
CL (1) | CL2012001359A1 (en) |
CO (1) | CO6551692A2 (en) |
EA (1) | EA026241B1 (en) |
EC (1) | ECSP12011986A (en) |
HK (1) | HK1175418A1 (en) |
IL (1) | IL219088A (en) |
MA (1) | MA33755B1 (en) |
MX (1) | MX2012005961A (en) |
NZ (1) | NZ599295A (en) |
PE (1) | PE20130036A1 (en) |
SG (1) | SG181050A1 (en) |
TN (1) | TN2012000245A1 (en) |
TW (1) | TW201129399A (en) |
UA (1) | UA107097C2 (en) |
UY (1) | UY33054A (en) |
WO (1) | WO2011064164A1 (en) |
ZA (1) | ZA201202598B (en) |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015169732A1 (en) * | 2014-05-07 | 2015-11-12 | Boehringer Ingelheim International Gmbh | Container, nebulizer and use |
WO2015169431A3 (en) * | 2014-05-07 | 2015-12-30 | Boehringer Ingelheim International Gmbh | Nebulizer, indicator device and container |
US9545487B2 (en) | 2012-04-13 | 2017-01-17 | Boehringer Ingelheim International Gmbh | Dispenser with encoding means |
US9682202B2 (en) | 2009-05-18 | 2017-06-20 | Boehringer Ingelheim International Gmbh | Adapter, inhalation device, and atomizer |
US9724482B2 (en) | 2009-11-25 | 2017-08-08 | Boehringer Ingelheim International Gmbh | Nebulizer |
US9744313B2 (en) | 2013-08-09 | 2017-08-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
US9757750B2 (en) | 2011-04-01 | 2017-09-12 | Boehringer Ingelheim International Gmbh | Medicinal device with container |
US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
US9943654B2 (en) | 2010-06-24 | 2018-04-17 | Boehringer Ingelheim International Gmbh | Nebulizer |
US10004857B2 (en) | 2013-08-09 | 2018-06-26 | Boehringer Ingelheim International Gmbh | Nebulizer |
US10011906B2 (en) | 2009-03-31 | 2018-07-03 | Beohringer Ingelheim International Gmbh | Method for coating a surface of a component |
US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
US10124129B2 (en) | 2008-01-02 | 2018-11-13 | Boehringer Ingelheim International Gmbh | Dispensing device, storage device and method for dispensing a formulation |
US10124125B2 (en) | 2009-11-25 | 2018-11-13 | Boehringer Ingelheim International Gmbh | Nebulizer |
US10722666B2 (en) | 2014-05-07 | 2020-07-28 | Boehringer Ingelheim International Gmbh | Nebulizer with axially movable and lockable container and indicator |
WO2022002993A1 (en) | 2020-07-03 | 2022-01-06 | Boehringer Ingelheim International Gmbh | Nebulizer |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101345770B1 (en) * | 2012-04-20 | 2013-12-27 | (주)연우 | A nose washer |
GB2507104A (en) * | 2012-10-19 | 2014-04-23 | Nicoventures Holdings Ltd | Electronic inhalation device |
US20150041558A1 (en) * | 2013-08-09 | 2015-02-12 | Boehringer Ingelheim International Gmbh | Nebulizer |
NZ714524A (en) * | 2013-08-20 | 2020-07-31 | Boehringer Ingelheim Vetmedica Gmbh | Inhaler |
GB201517089D0 (en) | 2015-09-28 | 2015-11-11 | Nicoventures Holdings Ltd | Vaping heat map system and method for electronic vapour provision systems |
TWI565531B (en) * | 2015-11-25 | 2017-01-11 | Motedo Co Ltd | Safe use of the sprayer |
EP3175722A1 (en) * | 2015-12-03 | 2017-06-07 | JT International S.A. | Inhaler device and consumable cartridge for same |
US11369760B2 (en) * | 2016-08-24 | 2022-06-28 | Anovent Pharmaceutical (U.S.), Llc | Inhalation atomizer comprising a blocking function and a counter |
CN111195382B (en) * | 2018-11-16 | 2022-04-19 | 微邦科技股份有限公司 | Locking structure of atomization drug delivery device |
TWI683677B (en) * | 2018-11-16 | 2020-02-01 | 微邦科技股份有限公司 | Locking structure of atomized drug delivery device |
AR118966A1 (en) * | 2019-05-24 | 2021-11-10 | Boehringer Ingelheim Vetmedica Gmbh | INHALER AND BREATH PROTECTION AND INDICATOR DEVICE |
CN115768294B (en) * | 2020-01-16 | 2024-04-02 | 汽化技术公司 | Personal vaporizer for use with vials |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996006011A2 (en) | 1994-08-11 | 1996-02-29 | Boehringer Ingelheim Kg | Closure cap and process for filling containers without forming gas bubbles |
US6259654B1 (en) * | 1997-03-28 | 2001-07-10 | Telaric, L.L.C. | Multi-vial medication organizer and dispenser |
WO2005077445A1 (en) * | 2004-02-12 | 2005-08-25 | Geir Jansen | Medicament dispenser |
US20060037612A1 (en) * | 2004-07-16 | 2006-02-23 | Sofotec Gmbh & Co. Kg | Inhaler for the administration of powdered pharmaceuticals, and a powder cartridge system for use with this inhaler |
WO2006125577A2 (en) | 2005-05-24 | 2006-11-30 | Boehringer Ingelheim International Gmbh | Nebuliser |
WO2007022898A2 (en) | 2005-08-24 | 2007-03-01 | Boehringer Ingelheim International Gmbh | Atomiser comprising a counter and an end of operation lock |
WO2009047173A2 (en) | 2007-10-01 | 2009-04-16 | Boehringer Ingelheim International Gmbh | Atomizer |
Family Cites Families (562)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1828864A (en) | 1923-02-20 | 1931-10-27 | Gilmont Products Corp | Method of filling bicompartment collapsible tubes |
GB414953A (en) | 1932-12-24 | 1934-08-16 | Josef Schoene | Medical injection syringe |
US2127401A (en) | 1937-11-15 | 1938-08-16 | Gillican Charles Crum | Method of packaging rosin |
US2161071A (en) | 1938-05-02 | 1939-06-06 | Zellerbach Paper Company | Method of packing frozen food |
US2321428A (en) | 1939-04-25 | 1943-06-08 | Ferdinand G Schloz | Nozzle |
US2329311A (en) | 1940-06-05 | 1943-09-14 | Harry F Waters | Method of producing liquid-containing packages |
US2362103A (en) | 1941-01-04 | 1944-11-07 | Arthur E Smith | Ampoule |
US2651303A (en) | 1948-11-13 | 1953-09-08 | Richard S Johnson | Inhaler |
US2720969A (en) | 1953-12-10 | 1955-10-18 | Becton Dickinson Co | Package and mounting for hypodermic syringe assembly |
DK83175C (en) | 1955-07-04 | 1957-07-22 | Grosserer Gorm Tage Hansen | Air control systems for greenhouses. |
US2974880A (en) | 1955-11-15 | 1961-03-14 | Drackett Co | Aerosol spray head |
US2793776A (en) | 1956-05-23 | 1957-05-28 | Lipari Michael | Container attachment for providing a compartmental dispensing receptacle |
US3172568A (en) | 1959-03-27 | 1965-03-09 | Modern Lab Inc | Pressurized dispensing device |
US3032823A (en) | 1960-05-26 | 1962-05-08 | Sherman Plastics Corp | Method of forming plastic articles |
GB951228A (en) | 1961-09-26 | 1964-03-04 | Ici Ltd | Packaging process |
FR1314002A (en) | 1961-11-24 | 1963-01-04 | Method and device for dispensing a non-compacted substance | |
US3299603A (en) | 1962-03-12 | 1967-01-24 | Continental Can Co | Method of filling pouches |
NL297349A (en) | 1962-08-31 | |||
US3354883A (en) | 1965-03-08 | 1967-11-28 | Southerland Elizabeth Lee | Disposable syringe having frangible means for mixing plural medicaments |
US3440144A (en) | 1965-05-21 | 1969-04-22 | Andersen Prod H W | Method and apparatus for checking and testing the effectiveness of sterilization |
US3457694A (en) | 1966-08-25 | 1969-07-29 | Hideo Tatibana | Method of and apparatus for fusion sealing the opening of flexible plastic bottle-like containers |
US3491803A (en) | 1966-10-03 | 1970-01-27 | Haskon Inc | Machine for filling with liquids containers having deformable side walls |
FR1502925A (en) | 1966-10-12 | 1967-11-24 | Vaporisateurs Marcel Franck | Improvements to piston pumps for dispensing liquids or fluid pastes |
GB1230472A (en) | 1967-07-10 | 1971-05-05 | ||
US3590557A (en) | 1968-03-07 | 1971-07-06 | Fr Hesser Maschinenfabrick Ag | Apparatus for closing packaging containers with elastically deformable walls |
US3580249A (en) | 1968-09-16 | 1971-05-25 | Kentaro Takaoka | Aerosol nebulizers |
US3858580A (en) | 1969-06-04 | 1975-01-07 | Ims Ltd | Intravenous container mixing assembly |
US3674028A (en) | 1969-06-04 | 1972-07-04 | Ims Ltd | Multi-mix |
BE751383R (en) | 1969-08-12 | 1970-12-03 | Oreal | PERFECTIONED VALVE FOR PRESSURIZED CONTAINER DISPENSER OF SEVERAL PRODUCTS |
US3655096A (en) | 1969-10-22 | 1972-04-11 | Pillsbury Co | Container for diluting and dispensing material |
US3949751A (en) | 1970-03-03 | 1976-04-13 | Fisons Limited | Method and device for dispensing medicament to the body |
US3674060A (en) | 1970-12-14 | 1972-07-04 | Continental Can Co | Apparatus for filling and adjusting the contents level in flexible containers |
BE788194A (en) | 1971-08-31 | 1973-02-28 | Thomae Gmbh Dr K | DEVICE FOR THE ADMINISTRATION OF MECHANICALLY DOSE QUANTITIES OF LIQUID OR SOLUTION MEDICINAL PRODUCTS |
US3861851A (en) | 1971-12-08 | 1975-01-21 | Schiemann Dr Wolfram | Apparatus for moulding the neck of an extruded hollow body |
US3802604A (en) | 1972-02-28 | 1974-04-09 | Oreal | Device for storing two products separately and dispensing them simultaneously |
DE2221101C3 (en) | 1972-04-28 | 1975-05-15 | Wolf-Geraete Gmbh, 5240 Betzdorf | Bottle-like mixing container |
US3933279A (en) | 1972-11-28 | 1976-01-20 | Ciba-Geigy Corporation | Aerosol dispenser for fluid products comprising a piston pump assembly for generating compressed air |
US3946732A (en) | 1973-08-08 | 1976-03-30 | Ampoules, Inc. | Two-chamber mixing syringe |
US3951310A (en) | 1974-02-11 | 1976-04-20 | V.C.A. Corporation | Spring-charged aerosol dispenser |
US3973603A (en) | 1974-06-18 | 1976-08-10 | Franz Henry H | Control for filling flexible bottles or containers |
DK140801B (en) | 1975-01-15 | 1979-11-19 | Nordisk Insulinlab | Process for the preparation of a stable long-acting insulin preparation. |
US3924741A (en) | 1975-03-04 | 1975-12-09 | Gibson Ass Inc | Two-compartment container |
US3953995A (en) | 1975-05-27 | 1976-05-04 | Haswell John W | Means for making double groove pulleys |
US4153689A (en) | 1975-06-13 | 1979-05-08 | Takeda Chemical Industries, Ltd. | Stable insulin preparation for nasal administration |
US4012472A (en) | 1975-07-17 | 1977-03-15 | Arbrook, Inc. | Medical fluids container |
US4174035A (en) | 1975-09-04 | 1979-11-13 | Georg Wiegner | Two-component container and package |
US4036439A (en) | 1975-09-24 | 1977-07-19 | Newman-Green, Inc. | Spray head for nebulization of fluids |
US4067499A (en) | 1976-02-17 | 1978-01-10 | Cohen Milton J | Non-aerosol continuous spray dispenser |
US4126559A (en) | 1976-03-30 | 1978-11-21 | Pall Corporation | Pharmaceutical filter |
US4094317A (en) | 1976-06-11 | 1978-06-13 | Wasnich Richard D | Nebulization system |
US4048997A (en) | 1976-11-01 | 1977-09-20 | Mpl, Inc. | Syringe with actinic radiation protection |
IT1075249B (en) | 1976-12-10 | 1985-04-22 | Ottina Luigi | TWO-CONTAINER DEVICE FOR THE INDEPENDENT STORAGE OF TWO COMPONENTS AND THE SYSTEMS PREPARATION OF A PRODUCT WITH THESE TWO COMPONENTS |
US4177938A (en) | 1977-06-30 | 1979-12-11 | Brina Guido J | Container with mixing cartridge |
US4178928A (en) | 1977-08-10 | 1979-12-18 | Tischlinger Edward A | Self injector |
US4245788A (en) | 1978-03-20 | 1981-01-20 | Wright Hershel E | Dispensing device for fluid material |
US4195730A (en) | 1978-06-20 | 1980-04-01 | General Foods Corporation | Container having separate storage facilities for two materials |
CA1097276A (en) | 1978-12-15 | 1981-03-10 | Marcel J. H. Staar | Package for storing and spraying small amounts of liquids |
US4315570A (en) | 1979-01-04 | 1982-02-16 | Jules Silver | Two-compartment container with means for dispersing contents of one compartment into the other compartment |
JPS5819535B2 (en) | 1979-04-16 | 1983-04-19 | 本州製紙株式会社 | How to seal a sealed container |
EP0018609B1 (en) | 1979-04-30 | 1983-09-21 | Hoechst Aktiengesellschaft | Aqueous solutions of proteins stable against denaturization, process for their manufacture, and their utilization |
DK374579A (en) | 1979-09-07 | 1981-03-08 | Nordisk Insulinlab | PROCEDURE FOR THE PREPARATION OF AN INJUCABLE INSULIN PREPARATION |
JPS5684246A (en) | 1979-11-28 | 1981-07-09 | Toppan Printing Co Ltd | Vessel |
US4377106A (en) | 1980-06-30 | 1983-03-22 | Realex Corporation | Tamper-resistant locking clip for dispensing pumps |
FR2487016A1 (en) | 1980-07-16 | 1982-01-22 | Aerosol Inventions Dev | METHOD FOR PREVENTING PREMATURE USE OF A MANUALLY CONTROLLED PUMP AND PUMP IMPLEMENTING SAID METHOD |
GB2083382B (en) | 1980-09-08 | 1984-06-20 | Metal Box Co Ltd | Forming can bodies |
DE3118783C2 (en) | 1981-05-12 | 1986-02-20 | Cantec, Inc., Fort Worth, Tex. | Device for beading the body of a sheet metal container |
JPS58501125A (en) | 1981-07-17 | 1983-07-14 | ノルデイスク・インスリンラボラトリウム | Stable aqueous therapeutic insulin preparation and method for producing the same |
US4516967A (en) | 1981-12-21 | 1985-05-14 | Kopfer Rudolph J | Wet-dry compartmental syringe |
ES520249A0 (en) | 1982-03-03 | 1984-04-16 | Nordisk Insulinlab | PROCEDURE FOR PRODUCING INSULIN PREPARATIONS. |
GB2123481B (en) | 1982-06-19 | 1985-04-17 | Lucas Ind Plc | C i engine fuel injection nozzles |
US4456016A (en) | 1982-07-01 | 1984-06-26 | Trutek Research, Inc. | Inhalation valve |
US4515586A (en) | 1982-11-30 | 1985-05-07 | Abbott Laboratories | Powder syringe mixing system |
US4476116A (en) | 1982-12-10 | 1984-10-09 | Syntex (U.S.A.) Inc. | Polypeptides/chelating agent nasal compositions having enhanced peptide absorption |
USRE33444E (en) | 1984-01-09 | 1990-11-20 | Fluid treating for removal of components or for transfer of heat, momentum-apparatus and method | |
NZ209900A (en) | 1984-10-16 | 1989-08-29 | Univ Auckland | Automatic inhaler |
US4964540A (en) | 1984-10-17 | 1990-10-23 | Exxel Container, Inc. | Pressurized fluid dispenser and method of making the same |
US4858830A (en) | 1985-03-20 | 1989-08-22 | Turbo Tek Enterprises, Inc. | Spraying device having an additive fluid dispenser at an exit end |
EP0386800A1 (en) | 1985-03-20 | 1990-09-12 | Turbo Tek Enterprises, Inc. | Spraying device having controlled additive fluid feed and a telescoping spray tube assembly |
US4682734A (en) | 1985-03-20 | 1987-07-28 | Turbo Tek Enterprises, Inc. | Spraying device having controlled additive fluid feed and a telescoping spray tube assembly |
US4603794A (en) | 1985-03-29 | 1986-08-05 | Battelle Development Corporation | Pressure multiplying dispenser |
IT1185850B (en) | 1985-08-02 | 1987-11-18 | Zambon Spa | DROP TANK CAP FOR BOTTLES |
JPS6274364A (en) | 1985-09-27 | 1987-04-06 | 株式会社 ニツシヨ− | Medical applicance |
US4727985A (en) | 1986-02-24 | 1988-03-01 | The Boc Group, Inc. | Mixing and dispensing apparatus |
AU601176B2 (en) | 1986-03-10 | 1990-09-06 | Kurt Burghart | Benzodiazepine aerosols |
DE3611690A1 (en) | 1986-04-08 | 1987-10-15 | Pfeiffer Erich Gmbh & Co Kg | DISCHARGE DEVICE FOR MIXED MEDIA |
DK179286D0 (en) | 1986-04-18 | 1986-04-18 | Nordisk Gentofte | INSULIN PREPARATION |
US4749082A (en) | 1986-05-05 | 1988-06-07 | Imperial Schrade Corp. | Knife transport/display package |
FI89458C (en) | 1986-11-06 | 1993-10-11 | Leiras Oy | INHALERINGSANORDNING |
US4796614A (en) | 1987-02-26 | 1989-01-10 | Trutek Research, Inc. | Collapsible inhalation valve |
US4952310A (en) | 1987-03-03 | 1990-08-28 | Mcmahan Anthony A | Intrachannel clarifier |
GB8710067D0 (en) | 1987-04-28 | 1987-06-03 | British Telecomm | Optical device |
JP2656944B2 (en) | 1987-04-30 | 1997-09-24 | クーパー ラボラトリーズ | Aerosolization of protein therapeutics |
DE3721308A1 (en) | 1987-06-27 | 1989-01-05 | Gerhard Hansen | METHOD FOR FILLING AND FOLLOWING WELDING A CONTAINER AND DEVICE AND CONTAINER FOR CARRYING OUT THIS METHOD |
US4840017A (en) | 1987-08-03 | 1989-06-20 | Baxter Healthcare Corporation | Method for filling collapsible containers |
DE3729206A1 (en) | 1987-08-28 | 1989-03-09 | Siemens Ag | METHOD FOR FORMING INK CHANNELS IN A WRITING HEAD FOR AN INK MOSAIC WRITING DEVICE |
EP0308181A1 (en) | 1987-09-14 | 1989-03-22 | Novo Nordisk A/S | Trans-mucosal delivery formulations and a method for preparation thereof |
FR2621818B1 (en) | 1987-10-19 | 1990-12-14 | Medipro | MEDICINE COMPRISING THE COMBINATION OF POLYMIXIN B, NETILMICIN AND AMPHOTERICIN B BY VAPORIZATION |
FR2621817B1 (en) | 1987-10-19 | 1990-12-14 | Medipro | DRUG COMPRISING POLYMYXIN B, TOBRAMYCIN AND AMPHOTERICIN B VAPORIZED |
FR2624015B1 (en) | 1987-12-03 | 1990-06-29 | Medipro | MEDICINE COMPRISING THE COMBINATION OF COLISTINE, TOBRAMYCIN AND AMPHOTERICIN B VAPORIZED |
DE3851750D1 (en) | 1987-12-11 | 1994-11-10 | Deutsche Forsch Luft Raumfahrt | SPIRAL NOZZLE FOR SPRAYING A LIQUID. |
US4805377A (en) | 1987-12-23 | 1989-02-21 | Entravision, Inc. | Method of packaging and sterilizing a pharmaceutical product |
DE3837595A1 (en) | 1988-04-14 | 1990-05-10 | Goldwell Gmbh | DOUBLE CHAMBER CONTAINER |
US4951661A (en) | 1988-06-08 | 1990-08-28 | Thayer Medical Corporation | Quick-connect adapter valve for connecting nebulizer and fluid ventilator hose |
JP2720899B2 (en) | 1988-07-15 | 1998-03-04 | 合資会社ミノファーゲン製薬本舗 | Transmucosal absorption enhancer and nasal administration agent using the same |
DE3827121A1 (en) | 1988-08-10 | 1990-02-15 | Hoechst Ag | METHOD FOR PRODUCING DES-B30 INSULINES AND DES-B30 INSULINE DERIVATIVES |
US5025957A (en) | 1988-10-07 | 1991-06-25 | Ryder International Corp. | Liquid dispenser nozzle assembly |
DE3834184C1 (en) | 1988-10-07 | 1989-12-28 | Bernd 7166 Sulzbach-Laufen De Hansen | |
JPH02104531A (en) | 1988-10-14 | 1990-04-17 | Toyo Jozo Co Ltd | Physiologically active peptide composition for nasal application |
US5059187A (en) | 1988-11-30 | 1991-10-22 | Dey Laboratories, Inc. | Method for the cleansing of wounds using an aerosol container having liquid wound cleansing solution |
FR2639903B1 (en) | 1988-12-05 | 1991-05-10 | Cebal | METHOD AND DEVICE FOR CLOSING A FLEXIBLE TUBE AFTER FILLING |
GB8828477D0 (en) | 1988-12-06 | 1989-01-05 | Riker Laboratories Inc | Medical aerosol formulations |
CA2006582A1 (en) | 1988-12-27 | 1990-06-27 | Gabriel Meyer | Storage and transfer bottle for storing two components of a medicinal substance |
US5129550A (en) | 1989-01-23 | 1992-07-14 | Battelle Memorial Institute | Spray bottle apparatus with force multiply pistons |
WO1990009781A1 (en) | 1989-02-23 | 1990-09-07 | Rorer International (Holdings), Inc. | Therapeutic aerosol formulations |
GB8904370D0 (en) | 1989-02-25 | 1989-04-12 | Cosmas Damian Ltd | Liquid delivery compositions |
JP2922935B2 (en) | 1989-08-11 | 1999-07-26 | 東興薬品工業株式会社 | Disposable adapter for nasal spray container for viscous liquid |
FR2653744B1 (en) | 1989-10-31 | 1992-03-06 | Valois | PROCESS FOR VACUUM PACKAGING OF PRODUCTS, IN PARTICULAR COSMETICS AND PHARMACEUTICALS, WITHIN DEFORMABLE TANKS OBTAINED BY A DISPENSING PUMP WITHOUT AIR INTAKE, DEVICE FOR IMPLEMENTING SAME AND DISPENSERS THEREOF. |
US4979941A (en) | 1989-12-05 | 1990-12-25 | International Medication Systems, Limited | Device suitable for mixing medication |
SK280967B6 (en) | 1990-03-02 | 2000-10-09 | Glaxo Group Limited | Inhalation device |
SG45171A1 (en) | 1990-03-21 | 1998-01-16 | Boehringer Ingelheim Int | Atomising devices and methods |
IT1243344B (en) | 1990-07-16 | 1994-06-10 | Promo Pack Sa | MULTI-DOSE INHALER FOR POWDER MEDICATIONS |
DE4027320C2 (en) | 1990-08-29 | 1993-09-30 | Ursapharm Arzneimittel Gmbh | Fluid dispenser for aseptic fluid |
US5230884A (en) | 1990-09-11 | 1993-07-27 | University Of Wales College Of Cardiff | Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations |
IL99699A (en) | 1990-10-10 | 2002-04-21 | Autoimmune Inc | Pharmaceutical oral, enteral or by-inhalation dosage form for suppressing an autoimmune response associated with type i diabetes |
JPH04177092A (en) | 1990-11-08 | 1992-06-24 | Toshiba Corp | Heat exchanger and manufacture thereof |
GB9024760D0 (en) | 1990-11-14 | 1991-01-02 | Riker Laboratories Inc | Inhalation device and medicament carrier |
US5352196A (en) | 1990-11-19 | 1994-10-04 | Habley Medical Technology Corporation | Mixing vial |
NZ241034A (en) | 1990-12-17 | 1995-03-28 | Minnesota Mining & Mfg | Inhaler device with a dosage control that deactivates an aerosol generator after predetermined time or dosage |
US5394866A (en) | 1991-03-05 | 1995-03-07 | Aradigm Corporation | Automatic aerosol medication delivery system and methods |
ES2179068T3 (en) | 1991-03-05 | 2003-01-16 | Aradigm Corp | METHOD AND DEVICE FOR CORRECTING THE DERIVATIVE DISPLACEMENT OF A FLOW PRESSURE DETECTOR. |
FR2673608A1 (en) | 1991-03-07 | 1992-09-11 | Chanel | Product dispenser comprising tamper-evidence means |
WO1992016192A1 (en) | 1991-03-15 | 1992-10-01 | Amgen Inc. | Pulmonary administration of granulocyte colony stimulating factor |
US5156918A (en) | 1991-03-28 | 1992-10-20 | Northwestern University | Self-assembled super lattices |
WO1992017231A1 (en) | 1991-03-28 | 1992-10-15 | Innomed, Inc. | Microelectronic inhaler having a counter and timer |
IT223172Z2 (en) | 1991-04-09 | 1995-06-13 | Tecnomedica Ricerche Srl | DEVICE FOR THE ADMINISTRATION OF DRUGS, PARTICULARLY TWO-COMPONENT PHARMA-CI |
AU651882B2 (en) | 1991-05-14 | 1994-08-04 | Visiomed Group Limited | Aerosol inhalation device |
DE4117078A1 (en) | 1991-05-25 | 1992-11-26 | Boehringer Ingelheim Kg | METHOD FOR PRODUCING THERAPEUTICALLY APPLICABLE AEROSOLS |
AU2178392A (en) | 1991-06-12 | 1993-01-12 | Minnesota Mining And Manufacturing Company | Albuterol sulfate suspension aerosol formulations |
JPH057246A (en) | 1991-06-27 | 1993-01-14 | Fujitsu Ltd | Camp-on service communication system |
ATE170778T1 (en) | 1991-06-28 | 1998-09-15 | Weston Medical Ltd | ATOMIZING NOZZLE |
US5222385A (en) | 1991-07-24 | 1993-06-29 | American National Can Company | Method and apparatus for reforming can bottom to provide improved strength |
EP0526393B1 (en) | 1991-07-30 | 1996-08-28 | Sulzer Chemtech AG | mixing-in device |
JPH0553470A (en) | 1991-08-29 | 1993-03-05 | Ricoh Co Ltd | Fixing unit |
US5246142A (en) | 1991-09-26 | 1993-09-21 | Dipalma Elio | Device for storing two products separately and subsequently mixing them |
US5456522A (en) | 1991-10-14 | 1995-10-10 | Kennametal Inc. | Concave cutter bit |
US5499751A (en) | 1992-01-21 | 1996-03-19 | Meyer; Gabriel | Device for storing a liquid medicinal substance and for administering eye drops |
US5282549A (en) | 1992-03-16 | 1994-02-01 | Williams Dispenser Corporation | Dispenser with an energy storage member and an overload prevention mechanism |
US5263842A (en) | 1992-03-30 | 1993-11-23 | Stanley-Bostitch, Inc. | Nail driver with improved nosepiece assembly |
SE9201718D0 (en) | 1992-06-03 | 1992-06-03 | Astra Ab | NASAL SPRAY DEVICE |
US5271153A (en) | 1992-06-11 | 1993-12-21 | The Procter & Gamble Company | Apparatus for assembling a thin film beam spring vent valve |
AU4384093A (en) | 1992-06-11 | 1994-01-04 | Procter & Gamble Company, The | Thin film beam spring vent valve and method and apparatus for assembling it |
CA2097866A1 (en) | 1992-06-11 | 1993-12-12 | Howard Norman Reiboldt | Method and apparatus for assembling a thin film beam spring vent valve |
US5261565A (en) | 1992-06-11 | 1993-11-16 | The Procter & Gamble Company | Thin film beam spring vent valve |
US5284133A (en) | 1992-07-23 | 1994-02-08 | Armstrong Pharmaceuticals, Inc. | Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means |
GB2273660B (en) | 1992-09-11 | 1996-07-17 | Aid Medic Ltd | Drug delivery arrangement |
US6007676A (en) | 1992-09-29 | 1999-12-28 | Boehringer Ingelheim International Gmbh | Atomizing nozzle and filter and spray generating device |
IL107120A (en) | 1992-09-29 | 1997-09-30 | Boehringer Ingelheim Int | Atomising nozzle and filter and spray generating device |
DE4237568C1 (en) | 1992-11-06 | 1994-05-11 | Dieter Dipl Ing Dr Med Koehler | Method and device for producing an aerosol |
US5339990A (en) | 1992-11-10 | 1994-08-23 | Wilder Robert E | Adjustable pump dispenser |
RO117414B1 (en) | 1992-12-09 | 2002-03-29 | Jager Paul D Waterbury | Pharmaceutical composition of gas dispersoid in solution |
EP0625917B1 (en) | 1992-12-15 | 1998-03-25 | Sanofi | Device for preparing a medicinal substance solution, suspension or emulsion |
US5888477A (en) | 1993-01-29 | 1999-03-30 | Aradigm Corporation | Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin |
US5934272A (en) | 1993-01-29 | 1999-08-10 | Aradigm Corporation | Device and method of creating aerosolized mist of respiratory drug |
CA2155933C (en) | 1993-02-12 | 2000-04-04 | James L. Levin | Pulmonary administration of scr1 and other complement inhibitory proteins |
US5399159A (en) | 1993-03-30 | 1995-03-21 | Origin Medsystems, Inc. | Apparatus and method for hand-held insufflation |
EP0960830A1 (en) | 1993-04-30 | 1999-12-01 | Minnesota Mining And Manufacturing Company | Seal configuration for aerosol canister |
JPH06312019A (en) | 1993-04-30 | 1994-11-08 | Shinko Kagaku Kk | Liquid medicine spray receptacle |
US6062430A (en) | 1993-05-05 | 2000-05-16 | Ing. Erich Pfeiffer Gmbh | Dispensing container with variable volume compensation |
US5709202A (en) | 1993-05-21 | 1998-01-20 | Aradigm Corporation | Intrapulmonary delivery of aerosolized formulations |
US5497763A (en) | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
JPH08510411A (en) | 1993-05-25 | 1996-11-05 | ヴェルディング,ヴィンフリート | Injection nozzle for adjusting the flow rate per time unit |
GB9312984D0 (en) | 1993-06-23 | 1993-08-04 | Bespak Plc | Atomising dispenser |
WO1995003034A1 (en) | 1993-07-19 | 1995-02-02 | Amgen Inc. | Stabilization of aerosolized proteins |
US5433343A (en) | 1993-07-30 | 1995-07-18 | Meshberg; Philip | Delivery system for measured quantities of liquids, especially medications |
US6596260B1 (en) | 1993-08-27 | 2003-07-22 | Novartis Corporation | Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol |
CA2170160C (en) | 1993-09-07 | 2002-08-27 | Frederic Neftel | Syringe device for mixing two compounds |
US5435884A (en) | 1993-09-30 | 1995-07-25 | Parker-Hannifin Corporation | Spray nozzle and method of manufacturing same |
JPH07165613A (en) | 1993-10-19 | 1995-06-27 | Dot:Kk | Carrier for nasal absorption medicine and physiologically active peptide composition |
JPH07118166A (en) | 1993-10-19 | 1995-05-09 | Dot:Kk | Insulin composition |
JPH07118164A (en) | 1993-10-19 | 1995-05-09 | Dot:Kk | Carrier for nasal absorption agent and physiologically active peptide composition |
JP2957154B2 (en) | 1997-11-18 | 1999-10-04 | 株式会社三五 | Pipe end forming method and apparatus |
US5518147A (en) | 1994-03-01 | 1996-05-21 | The Procter & Gamble Company | Collapsible pump chamber having predetermined collapsing pattern |
US6051256A (en) | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
SE9401220D0 (en) | 1994-04-11 | 1994-04-11 | Astra Ab | Valve |
US5451569A (en) | 1994-04-19 | 1995-09-19 | Hong Kong University Of Science And Technology R & D Corporation Limited | Pulmonary drug delivery system |
GB9408276D0 (en) | 1994-04-26 | 1994-06-15 | Bespak Plc | Dispensing pump |
GB9420971D0 (en) | 1994-05-06 | 1994-12-07 | Minnesota Mining & Mfg | Aerosol valves |
JP3414539B2 (en) | 1994-05-11 | 2003-06-09 | 有限会社ドット | Composition for nasal absorption |
US5435282A (en) | 1994-05-19 | 1995-07-25 | Habley Medical Technology Corporation | Nebulizer |
US5848588A (en) | 1994-05-25 | 1998-12-15 | Trudell Medical Group | Backpiece for receiving an MDI adapter in an aerosolization spacer |
KR960704591A (en) | 1994-05-25 | 1996-10-09 | 메이어 가브리엘 | DEVICE FOR THE PREPARATION FO A SOLUTION.A SUSPENSION OR AN EMULSION OF A MEDICINAL SUBSTANCE |
JP2930526B2 (en) | 1994-05-31 | 1999-08-03 | 株式会社キートロン | Injector type atomizer |
US5482030A (en) | 1994-06-13 | 1996-01-09 | Klein; David | Aerosol and non-aerosol spray counter |
WO1996000050A1 (en) | 1994-06-23 | 1996-01-04 | R.P. Scherer Corporation | Ocular treatment device |
GB2291135B (en) | 1994-07-06 | 1998-02-25 | Boehringer Ingelheim Kg | Device for dispensing fluid |
US5509404A (en) | 1994-07-11 | 1996-04-23 | Aradigm Corporation | Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values |
ATE251433T1 (en) | 1994-08-30 | 2003-10-15 | Pharmacia Ab | LIQUID CAN PACKAGING, EYE TREATMENT DEVICE AND USE THEREOF |
AU697676B2 (en) | 1994-09-21 | 1998-10-15 | Nektar Therapeutics | Apparatus and methods for dispersing dry powder medicaments |
US5503869A (en) | 1994-10-21 | 1996-04-02 | Glaxo Wellcome Inc. | Process for forming medicament carrier for dry powder inhalator |
US5622163A (en) * | 1994-11-29 | 1997-04-22 | Iep Group, Inc. | Counter for fluid dispensers |
WO1996019389A1 (en) | 1994-12-22 | 1996-06-27 | Pentel Kabushiki Kaisha | Discharge container |
PL320856A1 (en) | 1994-12-22 | 1997-11-10 | Astra Ab | Aerosol drug preparations |
US5499750A (en) | 1995-01-17 | 1996-03-19 | Manifold; William J. | Spraying device having a removable and replaceable bladder |
AUPN089295A0 (en) | 1995-02-02 | 1995-03-02 | International Diabetes Institute | Treatment of diabetic neuropathy |
JP2802488B2 (en) | 1995-02-08 | 1998-09-24 | 有限会社ドット | Bioactive peptide composition for nasal absorption |
US5685846A (en) | 1995-02-27 | 1997-11-11 | Schott Parenta Systems, Inc. | Dual chamber internal by-pass syringe assembly |
US5541569A (en) | 1995-02-28 | 1996-07-30 | Jang; Huey J. | Switch having a circuit breaker |
AR002976A1 (en) | 1995-03-31 | 1998-05-27 | Lilly Co Eli | PARENTERAL PHARMACEUTICAL FORMULATIONS OF LONG-TERM EFFECT OF INSULIN; CRYSTALS OF SUCH ANALOGUES APPLICABLE IN SUCH FORMULATIONS AND PROCEDURE OF THE FORMULATIONS MENTIONED |
US6427682B1 (en) | 1995-04-05 | 2002-08-06 | Aerogen, Inc. | Methods and apparatus for aerosolizing a substance |
ES2179192T3 (en) | 1995-04-14 | 2003-01-16 | Smithkline Beecham Corp | DOSING INHIBITOR FOR ALBUTEROL. |
US6392962B1 (en) | 1995-05-18 | 2002-05-21 | Rmp, Inc. | Method of sleep time measurement |
JP3462934B2 (en) | 1995-06-19 | 2003-11-05 | 株式会社吉野工業所 | Thin resin sealed container made of synthetic resin |
BR9609307B1 (en) | 1995-06-27 | 2010-03-09 | pharmaceutical preparation for the production of lung-propellant-free inhaled aerosols as well as aerosol comprising the same. | |
US6209538B1 (en) | 1995-08-02 | 2001-04-03 | Robert A. Casper | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
JPH11292787A (en) | 1995-08-15 | 1999-10-26 | Asahi Chem Ind Co Ltd | Transucosal preparation containing physiologically active peptide |
GB9516984D0 (en) | 1995-08-18 | 1995-10-18 | Pharmasol Ltd | Spray applicator |
EP0846011A1 (en) | 1995-08-18 | 1998-06-10 | Pharmasol Limited | Spray applicator |
JPH0977073A (en) | 1995-09-19 | 1997-03-25 | Yoshino Kogyosho Co Ltd | Thin-wall sealed container made of synthetic resin |
US5738087A (en) | 1995-09-21 | 1998-04-14 | King; Russell W. | Aerosol medication delivery system |
DE19536902A1 (en) | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Int | Miniature fluid pressure generating device |
DE19536903C2 (en) | 1995-10-04 | 1998-09-10 | Boehringer Ingelheim Int | Device for holding a fluidic component |
ES2190477T3 (en) | 1995-11-17 | 2003-08-01 | Ursatec Verpackung Gmbh | FLUID DISPENSER DESIGNED TO PROTECT CONTENT FROM CONTAMINATION. |
ES2128220B1 (en) | 1995-12-04 | 1999-12-16 | Cusi Lab | PHARMACEUTICAL CONTAINER OF TWO SEPARATE SUBSTANCES, WITH MIXING DEVICE, DOSAGE APPLICATION AND ITS ASSEMBLY PROCESS. |
DE19545226C1 (en) | 1995-12-05 | 1997-06-19 | Boehringer Ingelheim Int | Locking mechanism for a spring-operated output |
US7131441B1 (en) | 1995-12-07 | 2006-11-07 | Skyepharma Ag | Inhaler for multiple dosed administration of a pharmacological dry powder |
WO1997023208A1 (en) | 1995-12-21 | 1997-07-03 | Genelabs Technologies, Inc. | Taxane composition and method |
DE19549033C1 (en) | 1995-12-28 | 1997-05-28 | Boehringer Ingelheim Int | Mechanical counter for a dosing device |
WO1997027804A1 (en) | 1996-02-05 | 1997-08-07 | Aradigm Corporation | Ventilation imaging using a fine particle aerosol generator |
AU1723997A (en) | 1996-02-09 | 1997-08-28 | Westonbridge International Limited | Micromachined filter for a micropump |
GB9606188D0 (en) | 1996-03-23 | 1996-05-29 | Danbiosyst Uk | Pollysaccharide microspheres for the pulmonary delivery of drugs |
DE19615422A1 (en) | 1996-04-19 | 1997-11-20 | Boehringer Ingelheim Kg | Two-chamber cartridge for propellant-free MDIs |
JPH09315953A (en) | 1996-05-28 | 1997-12-09 | Dot:Kk | Physioligically active peptide composition for nasal absorption |
GB2316323B (en) | 1996-06-20 | 1999-09-22 | Aid Medic Ltd | Dispensing system |
GB9619445D0 (en) | 1996-09-18 | 1996-10-30 | Boots Co Plc | Fluid dispenser |
JP3666537B2 (en) | 1996-11-14 | 2005-06-29 | セイコーエプソン株式会社 | Method for manufacturing ink cartridge for ink jet recording apparatus |
FR2756546B1 (en) | 1996-11-29 | 1999-01-29 | Valois | DEVICE FOR FIXING A DISPENSING MEMBER ON A CONTAINER NECK |
FR2756502B1 (en) | 1996-12-03 | 1999-01-22 | Oreal | NOZZLE FOR A DEVICE FOR SPRAYING A LIQUID AND SPRAYING DEVICE PROVIDED WITH SUCH A NOZZLE |
US20030215396A1 (en) | 1999-09-15 | 2003-11-20 | Boehringer Ingelheim Pharma Kg | Method for the production of propellant gas-free aerosols from aqueous medicament preparations |
DE19653969A1 (en) | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | New aqueous pharmaceutical preparation for the production of propellant-free aerosols |
GB9626960D0 (en) | 1996-12-27 | 1997-02-12 | Glaxo Group Ltd | Valve for aerosol container |
EP0954282B1 (en) | 1997-01-16 | 2005-01-19 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
JP3940455B2 (en) | 1997-01-30 | 2007-07-04 | 武田薬品工業株式会社 | Two-chamber syringe |
US5829435A (en) | 1997-02-24 | 1998-11-03 | Aradigm Corporation | Prefilter for prevention of clogging of a nozzle in the generation of an aerosol and prevention of administration of undesirable particles |
DE19708406A1 (en) | 1997-03-03 | 1998-09-10 | Alfred Von Schuckmann | Device for dispensing substances |
SE9700936D0 (en) | 1997-03-14 | 1997-03-14 | Astra Ab | Inhalation device |
US7978564B2 (en) * | 1997-03-28 | 2011-07-12 | Carlos De La Huerga | Interactive medication container |
JPH1147274A (en) | 1997-06-03 | 1999-02-23 | Takeda Chem Ind Ltd | Two-compartment-type syringe and connector for two compartment type syringe |
IT1293005B1 (en) | 1997-06-10 | 1999-02-11 | Bernardino Parise | CONTAINER FOR CONCENTRATED POWDER OR LIQUID SUBSTANCES TO BE PLACED IN SOLUTION WITHIN AN ENVELOPE AT THE TIME OF USE |
KR100235460B1 (en) * | 1997-06-25 | 1999-12-15 | 유무성 | Waste-using camera having ability of recycling |
US5883193A (en) | 1997-07-01 | 1999-03-16 | Minnesota Mining And Manufacturing Company | Adhesive compositions with durability under conditions of high humidity |
MXPA00000068A (en) | 1997-07-04 | 2002-09-18 | Univ Southampton | Improved targeting of flying insects with insecticides and apparatus for charging liquids. |
CA2295831A1 (en) | 1997-07-18 | 1999-01-28 | Vasca, Inc. | Method and apparatus for percutaneously accessing an implanted port |
EP0894511A3 (en) | 1997-07-29 | 2001-02-07 | Chino, Mitsumasa | Dustproof mask |
US20060239930A1 (en) | 1997-08-04 | 2006-10-26 | Herbert Lamche | Process for nebulizing aqueous compositions containing highly concentrated insulin |
DE19733651A1 (en) | 1997-08-04 | 1999-02-18 | Boehringer Ingelheim Pharma | Aqueous aerosol preparations containing biologically active marrow molecules and processes for producing corresponding aerosols |
FR2767793B1 (en) | 1997-09-02 | 1999-11-19 | Valois Sa | DISTRIBUTION DEVICE WITH FIXING RING WITH CONICAL SLEEVE |
TR200000583T2 (en) | 1997-09-04 | 2000-07-21 | Heineken Technical Services B.V. | A device for the storage and distribution of beer and other carbonated drinks. |
DE19742559C2 (en) | 1997-09-26 | 1999-08-05 | Gaplast Gmbh | Container with a pump |
DE19742439C1 (en) | 1997-09-26 | 1998-10-22 | Boehringer Ingelheim Int | Fluid micro-filter |
US6458095B1 (en) | 1997-10-22 | 2002-10-01 | 3M Innovative Properties Company | Dispenser for an adhesive tissue sealant having a housing with multiple cavities |
US6395331B1 (en) | 1997-10-28 | 2002-05-28 | Yazaki Corporation | Transparent substrate bearing an anti-stain, hydrophobic coating, and process for making it |
US5902298A (en) | 1997-11-07 | 1999-05-11 | Bracco Research Usa | Medicament container stopper with integral spike access means |
GB2332372B (en) | 1997-12-08 | 2002-08-14 | Minnesota Mining & Mfg | Pharmaceutical aerosol compositions |
GB9827370D0 (en) | 1998-01-16 | 1999-02-03 | Pari Gmbh | Mouthpiece for inhalation therapy units |
US6685691B1 (en) | 1998-02-27 | 2004-02-03 | Boehringer Ingelheim Gmbh | Container for a medicinal liquid |
DE19808295A1 (en) | 1998-02-27 | 1999-11-11 | Boehringer Ingelheim Int | Medical fluid container |
US7963955B2 (en) | 1998-02-27 | 2011-06-21 | Boehringer Ingelheim International Gmbh | Container for a medicinal liquid |
US5975370A (en) | 1998-03-16 | 1999-11-02 | Owens-Illinois Closure Inc. | Tamper-evident plunger-hold-down attachment for pump dispenser |
US6171972B1 (en) | 1998-03-17 | 2001-01-09 | Rosemount Aerospace Inc. | Fracture-resistant micromachined devices |
US6113078A (en) | 1998-03-18 | 2000-09-05 | Lytesyde, Llc | Fluid processing method |
US6378714B1 (en) | 1998-04-20 | 2002-04-30 | Becton Dickinson And Company | Transferset for vials and other medical containers |
US6257233B1 (en) | 1998-06-04 | 2001-07-10 | Inhale Therapeutic Systems | Dry powder dispersing apparatus and methods for their use |
US6267154B1 (en) | 1998-06-05 | 2001-07-31 | Abbott Laboratories | System for storing mixing and administering a drug |
DE19851279B4 (en) | 1998-06-17 | 2006-05-24 | GSF - Forschungszentrum für Umwelt und Gesundheit GmbH | Inhalation unit for supplying medicines to the lungs |
US6423298B2 (en) | 1998-06-18 | 2002-07-23 | Boehringer Ingelheim Pharmaceuticals, Inc. | Pharmaceutical formulations for aerosols with two or more active substances |
IL140353A0 (en) | 1998-06-18 | 2002-02-10 | Boehringer Ingelheim Pharma | Pharmaceutical formulations for aerosols with two or more active substances |
WO2000001612A2 (en) | 1998-07-06 | 2000-01-13 | Iep Group, Inc. | Counter for fluid dispenser |
US6584976B2 (en) | 1998-07-24 | 2003-07-01 | 3M Innovative Properties Company | Face mask that has a filtered exhalation valve |
GB2333129A (en) | 1998-09-15 | 1999-07-14 | Thomas David White | Spray dispenser with collapsible container |
JP2957176B1 (en) | 1998-09-24 | 1999-10-04 | 株式会社三五 | Manufacturing method of double structure container |
SI1121112T1 (en) | 1998-10-17 | 2002-10-31 | Boehringer Ingelheim Pharma Kg | Stable formoterol concentrate |
DE19847968A1 (en) | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Separate storage of an active material and a solvent comprises a closure cap and a container, with a chamber attached to the unit. |
US6745763B2 (en) | 1998-10-27 | 2004-06-08 | Garth T. Webb | Vaporizing device for administering sterile medication |
US6152296A (en) | 1998-11-06 | 2000-11-28 | Shih; Kuang-Sheng | Additive holder for a pet bottle |
DE19851404A1 (en) | 1998-11-07 | 2000-05-11 | Boehringer Ingelheim Int | Pressure compensation device for a double tank |
US6110247A (en) | 1998-11-13 | 2000-08-29 | Mesosystems Technology, Inc. | Micromachined impactor pillars |
NL1010749C2 (en) | 1998-12-07 | 2000-06-08 | V O F Pharmasept | Holder for dosed and substantially germ-free dispensing of a liquid. |
US6186409B1 (en) | 1998-12-10 | 2001-02-13 | Bowles Fluidics Corporation | Nozzles with integrated or built-in filters and method |
US6352152B1 (en) | 1998-12-18 | 2002-03-05 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
US6390291B1 (en) | 1998-12-18 | 2002-05-21 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
US6315112B1 (en) | 1998-12-18 | 2001-11-13 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
US6119853A (en) | 1998-12-18 | 2000-09-19 | Glaxo Wellcome Inc. | Method and package for storing a pressurized container containing a drug |
DE19902844C1 (en) | 1999-01-20 | 1999-11-18 | Kendall Med Erzeugnisse Gmbh | Vaporizer for medicine, for inhalation purposes |
GB9902493D0 (en) * | 1999-02-05 | 1999-03-24 | Glaxo Group Ltd | Inhalation device |
ATE390960T1 (en) | 1999-02-14 | 2008-04-15 | Pfeiffer Erich Gmbh & Co Kg | DISPENSER FOR FLOWING MEDIA |
GB2347870A (en) | 1999-02-22 | 2000-09-20 | Sunrise Medical Hhg Inc | Medical nebuliser |
DE19940713A1 (en) | 1999-02-23 | 2001-03-01 | Boehringer Ingelheim Int | Diffusion resistant cartridge for storing and dosing liquids, especially for producing drug-containing inhalable aerosols, has three-shell structure with collapsible bag, container and rigid housing |
GB9909357D0 (en) | 1999-04-24 | 1999-06-16 | Glaxo Group Ltd | Medicament carrier |
FR2793707B1 (en) | 1999-05-21 | 2002-02-15 | Valois Sa | IMPROVED FLUID PRODUCT DISPENSING DEVICE |
DE19933330A1 (en) | 1999-07-16 | 2001-01-18 | Pfeiffer Erich Gmbh & Co Kg | Media Donor |
DE19937442A1 (en) | 1999-08-07 | 2001-02-08 | Pfeiffer Erich Gmbh & Co Kg | Dispenser for flowable media, in particular for atomizing liquids |
WO2001013885A1 (en) | 1999-08-20 | 2001-03-01 | Norton Healthcare Ltd. | Method to produce powders for pulmonary or nasal administration |
AU7340100A (en) * | 1999-08-31 | 2001-03-26 | Kimberly-Clark Worldwide, Inc. | Portable purification system |
DE19942792A1 (en) | 1999-09-08 | 2001-03-15 | Pfeiffer Erich Gmbh & Co Kg | Media Donor |
AT409800B (en) | 1999-09-13 | 2002-11-25 | Hoffmann La Roche | METHOD AND DEVICE FOR IMPROVING THE STORAGE LIFE OF TONOMETRIC LIQUIDS |
US6581596B1 (en) | 1999-09-24 | 2003-06-24 | Respironics, Inc. | Apparatus and method of providing high frequency variable pressure to a patient |
EP1220700B1 (en) | 1999-10-06 | 2003-04-09 | Eckardt, Angela | Breathing-controlled inhalation device for dry powder |
DE60007593T2 (en) | 1999-10-14 | 2004-11-11 | Becton, Dickinson And Co. | Nasal delivery device with atomizing nozzle |
GB2355252B (en) | 1999-10-14 | 2002-01-23 | Bespak Plc | Improvements in drug delivery devices |
US6136846A (en) | 1999-10-25 | 2000-10-24 | Supergen, Inc. | Formulation for paclitaxel |
IT1308581B1 (en) | 1999-12-03 | 2002-01-08 | Medel Italiana Srl | APPARATUS FOR SPRAYING A LIQUID, IN PARTICULAR FOR MEDICAL USE. |
US6302101B1 (en) | 1999-12-14 | 2001-10-16 | Daniel Py | System and method for application of medicament into the nasal passage |
DE19962110C2 (en) | 1999-12-22 | 2003-06-12 | Pari Gmbh | Inhalation nebulizer with one-piece valve element |
IT1317846B1 (en) | 2000-02-22 | 2003-07-15 | Chiesi Farma Spa | FORMULATIONS CONTAINING AN ANTICOLINERGIC DRUG FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE BRONCOPNEUMOPATHY. |
AU2001234005B2 (en) | 2000-02-28 | 2006-01-19 | Pharmakodex Limited | Improvements in or relating to the delivery of oral drugs |
US6689092B2 (en) | 2000-03-03 | 2004-02-10 | Boehringer International Gmbh | Needle-less injector of miniature type |
US6701928B2 (en) | 2000-04-06 | 2004-03-09 | Wake Forest University | Inhaler dispensing system adapters for laryngectomized subjects and associated methods |
US6644305B2 (en) | 2000-04-14 | 2003-11-11 | Trudell Medical International | Nasal inhaler |
US6948494B1 (en) | 2000-05-10 | 2005-09-27 | Innovative Devices, Llc. | Medicament container with same side airflow inlet and outlet and method of use |
AU2001261691A1 (en) | 2000-05-19 | 2001-12-03 | The Gillette Company | System for dispensing multi-component products |
JP5392880B2 (en) | 2000-05-22 | 2014-01-22 | キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ | Stable pharmaceutical solution formulation for pressurized metered dose inhalers |
US20020000225A1 (en) | 2000-06-02 | 2002-01-03 | Carlos Schuler | Lockout mechanism for aerosol drug delivery devices |
JP2001346878A (en) | 2000-06-12 | 2001-12-18 | Terumo Corp | Jetting type medicinal liquid-injecting device |
AU2001270074A1 (en) | 2000-06-22 | 2002-01-02 | Glaxo Group Limited | Method and package for storing a pressurized container containing a drug |
US6325248B1 (en) | 2000-07-05 | 2001-12-04 | Robert E. Corba | Container assembly |
US6363932B1 (en) | 2000-07-06 | 2002-04-02 | Clinical Technologies, Inc. | Aerosol enhancement device |
MXPA02012859A (en) | 2000-07-15 | 2003-05-14 | Glaxo Group Ltd | Medicament dispenser. |
US6435175B1 (en) | 2000-08-29 | 2002-08-20 | Sensormedics Corporation | Pulmonary drug delivery device |
DE10049200A1 (en) | 2000-10-05 | 2002-04-11 | Clariant Gmbh | Process for the production of azo colorants |
GB2367756B (en) | 2000-10-12 | 2003-01-08 | Bespak Plc | Dispensing apparatus |
DE10050994A1 (en) | 2000-10-14 | 2002-04-18 | Boehringer Ingelheim Pharma | New diphenylalkanoic acid azabicyclooctane ester quaternary salts useful as anticholinergic agents, especially in treatment of asthma and chronic obstructive pulmonary disease |
US6706726B2 (en) | 2000-10-14 | 2004-03-16 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anticholinergics which may be used as medicaments as well as processes for preparing them |
DE10050982A1 (en) | 2000-10-16 | 2002-04-18 | Pfeiffer Erich Gmbh & Co Kg | Spender for flowable media, e.g. pharmaceuticals, comprises a pump, a spray nozzle outlet opening and a protective cap |
DE20018518U1 (en) | 2000-10-28 | 2001-02-01 | Boehringer Ingelheim Pharma | Atomizer for nasal spray |
US20020137764A1 (en) | 2000-10-31 | 2002-09-26 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
US20020111363A1 (en) | 2000-10-31 | 2002-08-15 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
US6620438B2 (en) | 2001-03-08 | 2003-09-16 | Boehringer Ingelheim Pharma Kg | Pharmaceutical compositions based on anticholinergics and NK1-receptor antagonists |
US6641782B1 (en) | 2000-11-15 | 2003-11-04 | Polaroid Corporation | Apparatus for performing diagnostic testing |
FR2816523B1 (en) | 2000-11-15 | 2003-01-10 | Oreal | CLEANABLE DISPENSING HEAD AND DISPENSER THUS EQUIPPED |
EP1211628B1 (en) | 2000-11-30 | 2014-05-14 | Canon Kabushiki Kaisha | Inhaler and a discharge head control method |
US6915901B2 (en) | 2000-12-11 | 2005-07-12 | Marc Feinberg | Packaging assembly for surgical use |
US6722364B2 (en) | 2001-01-12 | 2004-04-20 | Becton, Dickinson And Company | Medicament inhalation delivery devices and methods for using the same |
DE10104367A1 (en) | 2001-02-01 | 2002-08-08 | Boehringer Ingelheim Pharma | Medicinal compositions containing betamimetics with fewer side effects |
FR2821573B1 (en) | 2001-03-05 | 2003-06-13 | Verbena Corp N V | PROFILED CHANNEL SPRAY NOZZLE |
GB0106046D0 (en) | 2001-03-12 | 2001-05-02 | Glaxo Group Ltd | Canister |
DE10111843A1 (en) | 2001-03-13 | 2002-09-19 | Boehringer Ingelheim Pharma | Compounds for the treatment of inflammatory diseases |
CA2439766C (en) | 2001-03-15 | 2008-12-09 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Nebulizer having cooling chamber |
US6550472B2 (en) | 2001-03-16 | 2003-04-22 | Aerogen, Inc. | Devices and methods for nebulizing fluids using flow directors |
DE60200946T2 (en) | 2001-03-26 | 2005-09-01 | 3M Innovative Properties Co., St. Paul | DOSSIER VALVE FOR A DOSIERINHALATOR WITH IMPROVED RIVER |
ATE367527T1 (en) | 2001-04-27 | 2007-08-15 | Hydrocision Inc | HIGH PRESSURE DISPOSABLE PUMP CASSETTE FOR USE IN MEDICAL FIELD |
US6725858B2 (en) | 2001-05-07 | 2004-04-27 | Hudson Respiratory Care Inc. | Valved aerosol tee adapter assembly |
GB0114175D0 (en) | 2001-06-11 | 2001-08-01 | Glaxo Group Ltd | Medicament dispenser |
DE10131178A1 (en) | 2001-06-29 | 2003-01-16 | Boehringer Ingelheim Pharma | Nebulizer for applying liquids to the eyes |
WO2003014832A1 (en) | 2001-08-10 | 2003-02-20 | Paul Mayo Holt | Methods and apparatus for use in photopolymer plate manufacture |
GB2372575B (en) | 2001-08-10 | 2003-01-15 | Chemence Ltd | Method for forming a sachet |
AR036358A1 (en) | 2001-08-28 | 2004-09-01 | Schering Corp | A DOSE INHALER MEASURES CONTAINING A SUSPENSION FORMULATION IN AEROSOL FOR INHALATION, A PROCESS FOR THE PRODUCTION OF THE FORMULATION, THE PRODUCT AND THE USE OF A FORMULATION FOR THE MANUFACTURE OF AN ASTHMA MEDICINAL PRODUCT |
CA2459867C (en) | 2001-09-06 | 2012-03-13 | Microdose Technologies, Inc. | Adaptors for inhalers to improve performance |
EA008165B1 (en) | 2001-09-18 | 2007-04-27 | Никомед Данмарк Апс | Compositions for treatment of common cold |
CA2464250C (en) | 2001-10-24 | 2008-08-05 | Frank-Christophe Lintz | Kit for the preparation of a pharmaceutical composition |
AU3297402A (en) | 2001-10-26 | 2003-10-30 | Dey, L.P. | An albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease |
US20030191151A1 (en) | 2001-10-26 | 2003-10-09 | Imtiaz Chaudry | Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease |
US6779520B2 (en) | 2001-10-30 | 2004-08-24 | Iep Pharmaceutical Devices Inc. | Breath actuated dry powder inhaler |
WO2003037259A2 (en) | 2001-10-30 | 2003-05-08 | The General Hospital Corporation | Methods for the prevention or treatment of bacterial and fungal infections |
TW565485B (en) | 2001-11-07 | 2003-12-11 | Sansha Electric Mfg Co Ltd | Power supply apparatus for welder |
DE10154237A1 (en) | 2001-11-07 | 2003-05-15 | Steag Microparts Gmbh | Manual sputterer, to spray liquid droplets on to a surface, has a spring acting on a piston with a manual release, to spray a portion of the stored liquid with a controlled droplet size |
WO2003045482A1 (en) | 2001-11-26 | 2003-06-05 | Bodrapan I/S | Inhalation device |
US20040092428A1 (en) | 2001-11-27 | 2004-05-13 | Hongming Chen | Oral pharmaceuticals formulation comprising paclitaxel, derivatives and methods of administration thereof |
US20050129620A1 (en) | 2001-12-07 | 2005-06-16 | Clark Verna L. | Metering valve and pharmaceutical metered dose inhaler and methods thereof |
NL1019562C2 (en) | 2001-12-13 | 2003-06-17 | Heineken Tech Services | Valve assembly for use with beverage delivery. |
RS52904A (en) | 2001-12-20 | 2006-12-15 | Bristol-Myers Squib Company | Pharmaceutical compositions of orally active taxane derivatives having enhanced bioavailability |
US6994083B2 (en) | 2001-12-21 | 2006-02-07 | Trudell Medical International | Nebulizer apparatus and method |
EP1321159A1 (en) | 2001-12-21 | 2003-06-25 | CHIESI FARMACEUTICI S.p.A. | Pressurized metered dose inhaler (pMDI) actuators with laser drilled orifices |
AU2002351271A1 (en) | 2001-12-21 | 2003-07-24 | Nektar Therapeutics | Capsule package with moisture barrier |
AU2003202828A1 (en) | 2002-01-17 | 2003-07-30 | Johan Massee | Method and forming machine for manufacturing a product having various diameters |
SE0200312D0 (en) | 2002-02-01 | 2002-02-01 | Astrazeneca Ab | Novel composition |
US6907879B2 (en) | 2002-02-04 | 2005-06-21 | Ndt | Agent delivery and aspiration device |
EP1474195B1 (en) | 2002-02-14 | 2005-12-07 | atmed Aktiengesellschaft | Inhalation aid |
GB0204328D0 (en) | 2002-02-25 | 2002-04-10 | Fyne Dynamics Ltd | Flow indicator |
GB0204829D0 (en) | 2002-03-01 | 2002-04-17 | Glaxo Group Ltd | A fluid dispensing device |
US7004164B2 (en) | 2002-03-21 | 2006-02-28 | Trudell Medical International | Indicating device for aerosol container |
US20040019073A1 (en) | 2002-04-11 | 2004-01-29 | Boehringer Ingelheim Pharma Gmbh Co. Kg | Aerosol formulation for inhalation containing a tiotropium salt |
US7417051B2 (en) | 2002-04-12 | 2008-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments comprising betamimetics and a novel anticholinergic |
BR0309185A (en) | 2002-04-12 | 2005-02-15 | Boehringer Ingelheim Pharma | Beta-mimetic drug and a new anticholinergic |
US6889690B2 (en) | 2002-05-10 | 2005-05-10 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages |
WO2003095010A2 (en) | 2002-05-10 | 2003-11-20 | Oriel Therapeutics, Inc. | Dry powder inhalers for use with piezoelectric polymer-driven delivery means, and associated blister package comprising a piezoelectric polymer material |
SI1509266T1 (en) | 2002-05-16 | 2009-12-31 | Boehringer Ingelheim Int | System comprising a nozzle and a fixing system |
US6832704B2 (en) | 2002-06-17 | 2004-12-21 | Summit Packaging Systems, Inc. | Metering valve for aerosol container |
DE10233150B4 (en) | 2002-07-22 | 2013-03-07 | Alfred Von Schuckmann | Hand-operated inhaler for powdered substances |
GB0217196D0 (en) | 2002-07-25 | 2002-09-04 | Glaxo Group Ltd | Medicament dispenser |
JP4261834B2 (en) | 2002-07-25 | 2009-04-30 | 泉工医科工業株式会社 | Liquid bag, liquid bag mouth member and method of manufacturing the same |
MXPA05001595A (en) | 2002-08-14 | 2005-04-25 | Boehringer Ingelheim Pharma | Aerosol formulation for inhalation containing an anticholinergic agent. |
US20040166065A1 (en) | 2002-08-14 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation comprising an anticholinergic |
US7337776B2 (en) | 2002-08-20 | 2008-03-04 | Aga Ab | Methods for easing pain and anxiety from atrial or ventricular defibrillation |
US7396341B2 (en) | 2002-08-28 | 2008-07-08 | Boehringer Ingelheim International Gmbh | Blocking device for a locking stressing mechanism having a spring-actuated output drive device |
EP2319583A1 (en) | 2002-08-29 | 2011-05-11 | Cipla Ltd. | Pharmaceutical products and compositions comprising salmeterol, budesonide and ipratropium |
PL375495A1 (en) | 2002-09-05 | 2005-11-28 | Boehringer Ingelheim Pharma Gmbh & Co.Kg | Device for discharging liquids, a cartridge suited therefor, and system comprised of the device for discharging liquids and of the cartridge |
US20040045546A1 (en) | 2002-09-05 | 2004-03-11 | Peirce Management, Llc | Pharmaceutical delivery system for oral inhalation through nebulization consisting of inert substrate impregnated with substance (S) to be solubilized or suspended prior to use |
JP4261851B2 (en) | 2002-09-11 | 2009-04-30 | キヤノン株式会社 | Inhalation device and method for controlling the inhalation device |
US20040102470A1 (en) | 2002-09-13 | 2004-05-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Method for improving the ability of patients suffering from lung diseases to participate in and benefit from pulmonary rehabilitation programs |
US6896129B2 (en) | 2002-09-20 | 2005-05-24 | Illinois Tool Works Inc. | Banded container package with opening feature |
US6776834B2 (en) | 2002-09-23 | 2004-08-17 | Ict Coatings N.V. | Composition for treating substrate and process of treatment |
US7024836B2 (en) | 2002-10-07 | 2006-04-11 | Becton, Dickinson And Company | Method for filling a container having at least one flexible component |
US6772911B2 (en) | 2002-10-15 | 2004-08-10 | Kevin Gee | Flow controller for container |
US7621266B2 (en) | 2003-01-14 | 2009-11-24 | Boehringer Ingelheim International Gmbh | Nozzle-system for a dispenser for fluids consisting of a nozzle and a nozzle-holder and/or screw cap |
DE10300983A1 (en) | 2003-01-14 | 2004-07-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Jet system for an inhaler, to deliver a mist of fluid droplets, has inner surfaces with micro- or nano-structures on the surfaces in contact with the aerosol flow to reduce precipitation |
GB0300939D0 (en) | 2003-01-16 | 2003-02-12 | Unilever Plc | Method of creating a cosmetic spray |
JP2004244109A (en) | 2003-01-24 | 2004-09-02 | Toyo Aerosol Ind Co Ltd | Aerosol device for two-liquid delivery |
GB2398253B (en) | 2003-02-11 | 2005-08-31 | Bespak Plc | Dispensing apparatus |
NZ542712A (en) | 2003-03-04 | 2008-11-28 | Norton Healthcare Ltd | Medicament dispensing device with a display indicative of the state of an internal medicament reservoir |
EA009087B1 (en) | 2003-03-20 | 2007-10-26 | Бёрингер Ингельхайм Фармасьютиклз, Инк. | Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants |
US6837089B2 (en) | 2003-04-03 | 2005-01-04 | Ball Corporation | Method and apparatus for reforming and reprofiling a bottom portion of a container |
FR2853635B1 (en) | 2003-04-09 | 2007-04-06 | Rexam Dispensing Sys | PULVERIZER PUSH BUTTON |
US7360537B2 (en) | 2003-04-16 | 2008-04-22 | Trudell Medical International | Antistatic medication delivery apparatus |
JP4154317B2 (en) | 2003-04-25 | 2008-09-24 | トヨタ自動車株式会社 | Fuel injection valve |
DE10320143A1 (en) | 2003-05-06 | 2004-12-16 | Pari GmbH Spezialisten für effektive Inhalation | Nebulizer connection device for respirators or the like |
DE20307306U1 (en) | 2003-05-09 | 2003-07-24 | Jump Health Co K | Medical, mechanical compressor atomizer |
DE10323603A1 (en) | 2003-05-20 | 2004-12-30 | Ing. Erich Pfeiffer Gmbh | Dosing device with a pump device |
AU2004241746A1 (en) | 2003-05-22 | 2004-12-02 | Nycomed Gmbh | Salmeterol and ciclesonide combination |
US7896264B2 (en) | 2003-06-30 | 2011-03-01 | Boehringer Ingelheim International Gmbh | Microstructured high pressure nozzle with built-in filter function |
EP1641569B1 (en) | 2003-06-30 | 2010-10-27 | Boehringer Ingelheim International GmbH | Microstructured high pressure nozzle with an in-built filter function |
US7273603B2 (en) | 2003-07-11 | 2007-09-25 | Boehringer Ingelheim International Gmbh | HFC solution formulations containing an anticholinergic |
US7600512B2 (en) * | 2003-07-14 | 2009-10-13 | Vortran Medical Technology 1, Inc. | Inhaler with breath actuated dose counter |
CA2532174A1 (en) | 2003-07-16 | 2005-02-17 | Boehringer Ingelheim Microparts Gmbh | A process for producing microfluidic arrangements from a plate-shaped composite structure |
CN100435970C (en) | 2003-07-16 | 2008-11-26 | 泊灵格英格尔海姆药品两合公司 | A process for producing microfluidic arrangements from a plate-shaped composite structure |
US20050028815A1 (en) | 2003-07-23 | 2005-02-10 | Deaton Daniel M. | Apparatus for electronic dosage counter |
DE10339197A1 (en) | 2003-08-22 | 2005-03-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Spray-dried amorphous powder with low residual moisture and good storage stability |
DE10345065A1 (en) | 2003-09-26 | 2005-04-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
JP3792690B2 (en) | 2003-11-11 | 2006-07-05 | 松本重工業株式会社 | Manufacturing method of deformed heat transfer tube for heat exchanger |
GB0328564D0 (en) | 2003-12-10 | 2004-01-14 | Dunne Stephen T | Variable flow discharge metered dose valve |
US20050191246A1 (en) | 2003-12-13 | 2005-09-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powders comprising low molecular dextran and methods of producing those powders |
DE10358387A1 (en) | 2003-12-13 | 2005-07-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder containing low molecular weight dextran and process for their preparation |
US7100530B2 (en) | 2003-12-15 | 2006-09-05 | Trudell Medical International, Inc. | Dose indicating device |
US8210166B2 (en) | 2003-12-16 | 2012-07-03 | Wolfe Tory Medical, Inc. | Vial multi-access adapter |
DE102004001451A1 (en) | 2004-01-08 | 2005-08-11 | Boehringer Ingelheim International Gmbh | Device for holding a fluidic component |
JP2007517529A (en) | 2004-01-09 | 2007-07-05 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | NOZZLE SYSTEM FOR LIQUID SUPPLEMENT DEVICE WITH NOZZLE, NOZZLE HOLDER AND / OR CHECK NUT |
GB0402694D0 (en) | 2004-02-06 | 2004-03-10 | Glaxo Group Ltd | A fluid dispenser |
DE102004009435A1 (en) | 2004-02-24 | 2005-12-08 | Boehringer Ingelheim International Gmbh | atomizer |
DE102004009434A1 (en) | 2004-02-24 | 2005-12-15 | Boehringer Ingelheim International Gmbh | atomizer |
US20050183718A1 (en) | 2004-02-24 | 2005-08-25 | Boehringer Ingelheim International Gmbh | Nebulizer |
PL1725285T3 (en) | 2004-03-10 | 2020-03-31 | Glaxo Group Limited | A dispensing device with restricting member |
US7258716B2 (en) | 2004-03-22 | 2007-08-21 | Joseph Gerard Birmingham | Microimpactor system having optimized impactor spacing |
US20050239778A1 (en) | 2004-04-22 | 2005-10-27 | Boehringer Ingelheim International Gmbh | Novel medicament combinations for the treatment of respiratory diseases |
KR20070012509A (en) | 2004-04-24 | 2007-01-25 | 인레인지 시스템즈, 인크. | Universal medication carrier |
DE102004021789A1 (en) | 2004-05-03 | 2006-04-27 | Boehringer Ingelheim International Gmbh | Atomizers for dispensing liquids for medical purposes |
DE102004022926A1 (en) | 2004-05-10 | 2005-12-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Spray-dried powders containing at least one 1,4 O-linked sucrose derivative and process for their preparation |
US7611709B2 (en) | 2004-05-10 | 2009-11-03 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives |
DE102004022928A1 (en) | 2004-05-10 | 2005-12-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder containing novel oligosaccharide mixtures and process for their preparation |
DE102004022927A1 (en) | 2004-05-10 | 2005-12-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 1,4 O-linked sucrose derivatives for the stabilization of antibodies or antibody derivatives |
US7191776B2 (en) | 2004-05-10 | 2007-03-20 | Smiths Medical Asd, Inc. | Nebulizer breathing system |
US7723306B2 (en) | 2004-05-10 | 2010-05-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation |
US7727962B2 (en) | 2004-05-10 | 2010-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder comprising new compositions of oligosaccharides and methods for their preparation |
US7448385B2 (en) | 2004-06-07 | 2008-11-11 | Purepharm Inc. | Nasal adaptation of an oral inhaler device |
DE102004031673B4 (en) | 2004-06-30 | 2009-04-16 | Erbe Elektromedizin Gmbh | Medical pump |
SE0401773D0 (en) * | 2004-07-02 | 2004-07-02 | Astrazeneca Ab | An inhalation and a method for assessing said inhalation device |
CA2571519C (en) | 2004-07-02 | 2013-05-14 | Boehringer Ingelheim International Gmbh | Aerosol suspension formulations containing tg 227 ea or tg 134 a as a propellant |
EP1616629B1 (en) | 2004-07-13 | 2014-04-02 | Aptar Radolfzell GmbH | Actuation device for a fluid dispenser |
WO2006011638A1 (en) | 2004-07-28 | 2006-02-02 | Dainippon Sumitomo Pharma Co., Ltd. | Film coated tablet having plural coats |
DE102004038885A1 (en) | 2004-08-10 | 2006-02-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
GB2417024B (en) | 2004-08-11 | 2007-01-03 | Bespak Plc | Improvements in metering valves for dispensers |
EP1791534A1 (en) | 2004-09-09 | 2007-06-06 | Cipla Ltd. | Pharmaceutical composition comprising an isomer of a betamimetic agent and an anti-cholinergic agent |
US8557861B2 (en) | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
WO2006037636A2 (en) | 2004-10-06 | 2006-04-13 | Boehringer Ingelheim International Gmbh | Dispensing device, storage device and method for dispensing powder |
GB0422413D0 (en) | 2004-10-08 | 2004-11-10 | Breath Ltd | High efficiency nebulisation |
US20090007904A1 (en) | 2004-10-12 | 2009-01-08 | Aradigm Corporation | Device and Method for Generating an Aerosol From a Liquid Formulation and Ensuring Its Sterility |
DE102004052360A1 (en) | 2004-10-28 | 2006-05-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Process for the preparation of a container with a container opening and container produced by this method |
GB0425518D0 (en) * | 2004-11-19 | 2004-12-22 | Clinical Designs Ltd | Substance source |
MXPA05001982A (en) | 2004-12-22 | 2006-06-21 | Ursapharm Arzneimittel Gmbh | Fluid dispenser. |
EP1838371B1 (en) | 2005-01-20 | 2020-09-09 | Trudell Medical International | Dispensing device |
GB2422786B (en) | 2005-03-03 | 2007-05-23 | Bespak Plc | Dispenser |
US20060225734A1 (en) | 2005-04-08 | 2006-10-12 | Ox-Gen Inc. | Filter for oxygen delivery systems |
GB0507224D0 (en) | 2005-04-09 | 2005-05-18 | Glaxo Group Ltd | A fluid dispensing device |
TWI442951B (en) | 2005-04-14 | 2014-07-01 | Astrazeneca Ab | Inhaler counter |
EP1871271B1 (en) | 2005-04-22 | 2018-04-11 | Becton, Dickinson and Company | Prepackaged medical device and method |
GB2425603B (en) * | 2005-04-27 | 2009-03-18 | Hewlett Packard Development Co | Apparatus that uses consumable items and a method of managing such apparatus |
WO2006126014A2 (en) | 2005-05-26 | 2006-11-30 | Incro Limited | A check valve and a split-body fluid device having such a check valve |
DE102005029498B4 (en) | 2005-06-24 | 2007-08-30 | Pari GmbH Spezialisten für effektive Inhalation | Inhalation therapy device |
DE102005029746B4 (en) | 2005-06-24 | 2017-10-26 | Boehringer Ingelheim International Gmbh | atomizer |
WO2007011475A1 (en) | 2005-07-15 | 2007-01-25 | Albemarle Corporation | Middle phase micro emulsions and process of making and using the same |
DE102005035705A1 (en) | 2005-07-27 | 2007-02-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | pharmaceutical blister |
US7980045B2 (en) | 2006-06-14 | 2011-07-19 | International Packaging Solutions Llc | Systems and methods for filling a collapsible container |
GB0518770D0 (en) | 2005-09-14 | 2005-10-26 | Glaxo Group Ltd | A closure for a dispensing device |
US20090032427A1 (en) | 2005-09-29 | 2009-02-05 | Nektar Therapeutics | Receptacles and Kits, Such as for Dry Powder Packaging |
US20070090576A1 (en) | 2005-10-20 | 2007-04-26 | Boehringer Ingelheim International Gmbh | Process for forming a container opening |
EP1779933A1 (en) | 2005-10-26 | 2007-05-02 | The Procter and Gamble Company | Dispenser for a liquid |
DE102005055957A1 (en) | 2005-11-24 | 2007-07-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
DE102005055961A1 (en) | 2005-11-24 | 2007-05-31 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical composition containing specific concentration of quaternary ammonium anticholinergic agent, useful for treatment, by inhalation, of respiratory tract diseases |
DE102005055960A1 (en) | 2005-11-24 | 2007-07-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
DE102005055963A1 (en) | 2005-11-24 | 2007-07-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
DE102005055958A1 (en) | 2005-11-24 | 2007-07-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
EP1795221A1 (en) | 2005-12-02 | 2007-06-13 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
US7380575B2 (en) | 2005-12-20 | 2008-06-03 | Scholle Corporation | Filler device for filling flexible bags |
JP4877504B2 (en) | 2006-01-27 | 2012-02-15 | マックス株式会社 | Gas cartridge |
DE102006053374A1 (en) | 2006-02-09 | 2007-08-16 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical formulation for aerosols with two or more active substances and at least one surface-active substance |
JP2007238074A (en) | 2006-02-10 | 2007-09-20 | Aisin Seiki Co Ltd | Vehicular roof automatic opening/closing device |
US7959609B2 (en) | 2006-02-14 | 2011-06-14 | Battelle Memorial Institute | Accurate metering system |
EP1993736B1 (en) | 2006-03-07 | 2019-05-22 | Boehringer Ingelheim International GmbH | Swirl |
EP1834705B1 (en) | 2006-03-13 | 2011-09-14 | Ing. Erich Pfeiffer GmbH | Discharge device for a flowable medium |
WO2007109606A2 (en) | 2006-03-17 | 2007-09-27 | Csp Technologies, Inc. | Moisture-tight primary packaging for a dry powder inhaler |
EP2007451B1 (en) | 2006-03-21 | 2018-11-07 | SHL Group AB | Dose information device |
US20070221211A1 (en) | 2006-03-27 | 2007-09-27 | Boris Sagalovich | Apparatus and process for inhaling medicines |
DE102006022002A1 (en) | 2006-05-10 | 2007-11-15 | Boehringer Ingelheim International Gmbh | Atomizers and methods for atomizing fluid |
WO2007134967A1 (en) | 2006-05-19 | 2007-11-29 | Boehringer Ingelheim International Gmbh | Propellant-free inhalation aerosol formulation containing ipratropium bromide and salbutamol sulfate |
CA2652694A1 (en) | 2006-05-19 | 2007-11-29 | Boehringer Ingelheim International Gmbh | Aerosol formulation containing ipratropium bromide and salbutamol sulfate |
DE102006023756A1 (en) | 2006-05-20 | 2007-11-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ethanol-containing aerosol formulation for inhalation |
DE102006023770A1 (en) | 2006-05-20 | 2007-11-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Propellant-free aerosol formulation for inhalation |
GB0610541D0 (en) * | 2006-05-26 | 2006-07-05 | Bespak Plc | Improvements in or relating to dispensing apparatus |
DE102006025871A1 (en) | 2006-06-02 | 2007-12-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | atomizer |
DE102006025884A1 (en) | 2006-06-02 | 2007-12-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Adapter with a connector for a nebulizer |
GB0614621D0 (en) | 2006-07-24 | 2006-08-30 | 3M Innovative Properties Co | Metered dose dispensers |
US8141550B2 (en) * | 2006-08-01 | 2012-03-27 | Trudell Medical International | Dispensing device |
AU2007287550A1 (en) | 2006-08-22 | 2008-02-28 | Glaxo Group Limited | Drug dispenser |
FR2907435B1 (en) | 2006-10-20 | 2009-01-09 | Valois Sas | DEVICE FOR DISPENSING FLUID PRODUCT. |
DE202006017793U1 (en) | 2006-11-22 | 2007-01-11 | Tsai, Chang-Keng | Pneumatic fluid dispenser has double-walled container of flexible material, with flexible inner layer to form collapsible chamber, and flexible outer layer connected by open end to suction device of dispenser cap |
UA95506C2 (en) | 2006-12-22 | 2011-08-10 | Альміраль, С.А. | Inhalation device for powder drugs |
GB0700839D0 (en) | 2007-01-17 | 2007-02-21 | Braithwaite Philip | Device |
US20100095957A1 (en) | 2007-03-02 | 2010-04-22 | Corbco, Inc. | Manually operated monodose nasal sprayer device |
EP2134396A2 (en) | 2007-04-06 | 2009-12-23 | Becton, Dickinson and Company, Wagner, Jaconda | Disposable spacer for inhalation delivery of aerosolized drugs and vaccines |
EP2505267B1 (en) | 2007-04-23 | 2019-06-26 | Silgan Dispensing Systems Corporation | Tamper evident nozzle shield and methods for using the same |
DE102007023012A1 (en) | 2007-05-15 | 2008-11-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Atomizer and filter |
GB0710488D0 (en) | 2007-06-01 | 2007-07-11 | Innovatek Medical Ltd | Methods of treating components of a medical dispenser device |
EP2020249A1 (en) * | 2007-08-01 | 2009-02-04 | Boehringer Ingelheim Pharma GmbH & Co. KG | Inhalator |
ITMI20071936A1 (en) | 2007-10-08 | 2008-01-07 | Lumson Spa | METHOD FOR THE REALIZATION OF A DEVICE TO INCLUDE AIR HOLD AND TO SUPPLY FLUID SUBSTANCES AND DEVICE SO IT IS OBTAINED |
JP2009101258A (en) | 2007-10-19 | 2009-05-14 | Canyon Corp | Pump dispenser |
EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
WO2009090245A1 (en) * | 2008-01-16 | 2009-07-23 | Bang & Olufsen Medicom A/S | A dispenser |
NZ586655A (en) | 2008-01-23 | 2012-03-30 | Astrazeneca Ab | A medical dispenser with a display which is covered when dispensing action is in progress |
WO2009103510A1 (en) | 2008-02-19 | 2009-08-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Cartridge system |
EA201001453A1 (en) * | 2008-03-17 | 2011-04-29 | Бёрингер Ингельхайм Интернациональ Гмбх | TANK AND SPRAYER |
US8096420B2 (en) | 2008-04-30 | 2012-01-17 | Ethicon Endo-Surgery, Inc. | Universal blister package |
EP2135632A1 (en) | 2008-06-20 | 2009-12-23 | Boehringer Ingelheim International Gmbh | Inhalator |
AR072865A1 (en) | 2008-07-08 | 2010-09-29 | Schering Corp | COVER FOR AEROSOL CANS FOR DOSE INHALER MEASURES |
CN102159265B (en) | 2008-07-15 | 2015-09-16 | Shl集团有限责任公司 | Drug delivery device |
US8033518B2 (en) | 2008-10-08 | 2011-10-11 | Kurt Cameron Schuchman | Beverage holder device |
US20120132199A1 (en) | 2009-02-18 | 2012-05-31 | Boehringer Ingelheim International Gmbh | Atomizer |
WO2010094305A1 (en) | 2009-02-18 | 2010-08-26 | Boehringer Ingelheim International Gmbh | Device, cartridge and method for dispensing a liquid |
ES2657238T3 (en) | 2009-02-18 | 2018-03-02 | Boehringer Ingelheim International Gmbh | Device, cartridge and method for distributing a liquid |
EP2236227B1 (en) | 2009-03-30 | 2013-12-18 | Boehringer Ingelheim International GmbH | Forming tool with a rotatable base body |
EP2236224B1 (en) | 2009-03-30 | 2013-03-06 | Boehringer Ingelheim International GmbH | Forming tool with a rotatable basis body for forming an inhalator cartridge and use of such a tool |
EP2414560B1 (en) | 2009-03-31 | 2013-10-23 | Boehringer Ingelheim International GmbH | Method for coating a surface of a component |
JP5763053B2 (en) | 2009-05-18 | 2015-08-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Adapter, inhaler and atomizer |
TW201109056A (en) | 2009-06-02 | 2011-03-16 | Sanofi Aventis Deutschland | Delivery of two or more medicaments through a single dose selection and single dispense interface |
EP2275160A1 (en) | 2009-07-13 | 2011-01-19 | Boehringer Ingelheim International Gmbh | High pressure chamber |
CA2780858C (en) | 2009-11-25 | 2017-09-19 | Boehringer Ingelheim International Gmbh | Nebulizer |
EA026241B1 (en) | 2009-11-25 | 2017-03-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Nebulizer |
EP2504051B1 (en) | 2009-11-25 | 2019-09-04 | Boehringer Ingelheim International GmbH | Nebulizer |
US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
US8834443B2 (en) | 2010-03-22 | 2014-09-16 | Alex Yeung | Injection safety system |
WO2011131779A1 (en) | 2010-04-23 | 2011-10-27 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and drug reservoir with mechanical coding mechanism |
WO2011154295A2 (en) | 2010-06-08 | 2011-12-15 | Boehringer Ingelheim International Gmbh | Medical device having a counter having a preset counting range, device having counter variation |
US9943654B2 (en) | 2010-06-24 | 2018-04-17 | Boehringer Ingelheim International Gmbh | Nebulizer |
WO2012130757A1 (en) | 2011-04-01 | 2012-10-04 | Boehringer Ingelheim International Gmbh | Medical device comprising a container |
WO2012161685A1 (en) | 2011-05-23 | 2012-11-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
DK2526989T3 (en) | 2011-05-23 | 2020-04-06 | Boehringer Ingelheim Int | SYSTEM INCLUDING A SPRAYER |
US10080853B2 (en) | 2011-05-23 | 2018-09-25 | Boehringer Ingelheim International Gmbh | Nebulizer |
US20150306322A9 (en) | 2012-01-23 | 2015-10-29 | Sanofi Sa | Inhalation Device |
WO2013152894A1 (en) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Atomiser with coding means |
EP3030298B1 (en) | 2013-08-09 | 2017-10-11 | Boehringer Ingelheim International GmbH | Nebulizer |
ES2836977T3 (en) | 2013-08-09 | 2021-06-28 | Boehringer Ingelheim Int | Nebulizer |
US20150041558A1 (en) | 2013-08-09 | 2015-02-12 | Boehringer Ingelheim International Gmbh | Nebulizer |
PL3139979T3 (en) | 2014-05-07 | 2023-12-27 | Boehringer Ingelheim International Gmbh | Unit, nebulizer and method |
MX2016014403A (en) | 2014-05-07 | 2017-01-20 | Boehringer Ingelheim Int | Container, indicator device, and nebulizer. |
-
2010
- 2010-11-22 EA EA201200775A patent/EA026241B1/en not_active IP Right Cessation
- 2010-11-22 AP AP2012006207A patent/AP3141A/en active
- 2010-11-22 UA UAA201207260A patent/UA107097C2/en unknown
- 2010-11-22 NZ NZ599295A patent/NZ599295A/en unknown
- 2010-11-22 JP JP2012540382A patent/JP5715640B2/en active Active
- 2010-11-22 AU AU2010323220A patent/AU2010323220B2/en active Active
- 2010-11-22 MX MX2012005961A patent/MX2012005961A/en not_active Application Discontinuation
- 2010-11-22 WO PCT/EP2010/067902 patent/WO2011064164A1/en active Application Filing
- 2010-11-22 CN CN201410431395.0A patent/CN104225735B/en active Active
- 2010-11-22 PE PE2012000699A patent/PE20130036A1/en not_active Application Discontinuation
- 2010-11-22 EP EP10781681.1A patent/EP2504052B1/en active Active
- 2010-11-22 KR KR1020127016237A patent/KR101782306B1/en active IP Right Grant
- 2010-11-22 CA CA2781792A patent/CA2781792C/en active Active
- 2010-11-22 SG SG2012038410A patent/SG181050A1/en unknown
- 2010-11-22 CN CN201080052884.5A patent/CN102686260B/en active Active
- 2010-11-22 BR BR112012012475-7A patent/BR112012012475B1/en active IP Right Grant
- 2010-11-23 US US12/952,493 patent/US9724482B2/en active Active
- 2010-11-24 AR ARP100104350A patent/AR079154A1/en active IP Right Grant
- 2010-11-24 UY UY0001033054A patent/UY33054A/en not_active Application Discontinuation
- 2010-11-24 TW TW099140638A patent/TW201129399A/en unknown
-
2012
- 2012-04-05 IL IL219088A patent/IL219088A/en active IP Right Grant
- 2012-04-11 ZA ZA2012/02598A patent/ZA201202598B/en unknown
- 2012-05-16 MA MA34875A patent/MA33755B1/en unknown
- 2012-05-17 CO CO12081916A patent/CO6551692A2/en not_active Application Discontinuation
- 2012-05-21 TN TNP2012000245A patent/TN2012000245A1/en unknown
- 2012-05-25 CL CL2012001359A patent/CL2012001359A1/en unknown
- 2012-06-19 EC ECSP12011986 patent/ECSP12011986A/en unknown
-
2013
- 2013-03-07 HK HK13102847.6A patent/HK1175418A1/en not_active IP Right Cessation
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996006011A2 (en) | 1994-08-11 | 1996-02-29 | Boehringer Ingelheim Kg | Closure cap and process for filling containers without forming gas bubbles |
US6259654B1 (en) * | 1997-03-28 | 2001-07-10 | Telaric, L.L.C. | Multi-vial medication organizer and dispenser |
WO2005077445A1 (en) * | 2004-02-12 | 2005-08-25 | Geir Jansen | Medicament dispenser |
US20060037612A1 (en) * | 2004-07-16 | 2006-02-23 | Sofotec Gmbh & Co. Kg | Inhaler for the administration of powdered pharmaceuticals, and a powder cartridge system for use with this inhaler |
WO2006125577A2 (en) | 2005-05-24 | 2006-11-30 | Boehringer Ingelheim International Gmbh | Nebuliser |
WO2007022898A2 (en) | 2005-08-24 | 2007-03-01 | Boehringer Ingelheim International Gmbh | Atomiser comprising a counter and an end of operation lock |
WO2009047173A2 (en) | 2007-10-01 | 2009-04-16 | Boehringer Ingelheim International Gmbh | Atomizer |
Cited By (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10124129B2 (en) | 2008-01-02 | 2018-11-13 | Boehringer Ingelheim International Gmbh | Dispensing device, storage device and method for dispensing a formulation |
US10011906B2 (en) | 2009-03-31 | 2018-07-03 | Beohringer Ingelheim International Gmbh | Method for coating a surface of a component |
US9682202B2 (en) | 2009-05-18 | 2017-06-20 | Boehringer Ingelheim International Gmbh | Adapter, inhalation device, and atomizer |
US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
US9724482B2 (en) | 2009-11-25 | 2017-08-08 | Boehringer Ingelheim International Gmbh | Nebulizer |
US10124125B2 (en) | 2009-11-25 | 2018-11-13 | Boehringer Ingelheim International Gmbh | Nebulizer |
US9943654B2 (en) | 2010-06-24 | 2018-04-17 | Boehringer Ingelheim International Gmbh | Nebulizer |
US9757750B2 (en) | 2011-04-01 | 2017-09-12 | Boehringer Ingelheim International Gmbh | Medicinal device with container |
US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
US9545487B2 (en) | 2012-04-13 | 2017-01-17 | Boehringer Ingelheim International Gmbh | Dispenser with encoding means |
US10220163B2 (en) | 2012-04-13 | 2019-03-05 | Boehringer Ingelheim International Gmbh | Nebuliser with coding means |
US10894134B2 (en) | 2013-08-09 | 2021-01-19 | Boehringer Ingelheim International Gmbh | Nebulizer |
US9744313B2 (en) | 2013-08-09 | 2017-08-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
US10004857B2 (en) | 2013-08-09 | 2018-06-26 | Boehringer Ingelheim International Gmbh | Nebulizer |
US11642476B2 (en) | 2013-08-09 | 2023-05-09 | Boehringer Ingelheim International Gmbh | Nebulizer |
US10716905B2 (en) | 2014-02-23 | 2020-07-21 | Boehringer Lngelheim International Gmbh | Container, nebulizer and use |
US10195374B2 (en) | 2014-05-07 | 2019-02-05 | Boehringer Ingelheim International Gmbh | Container, nebulizer and use |
US10099022B2 (en) | 2014-05-07 | 2018-10-16 | Boehringer Ingelheim International Gmbh | Nebulizer |
AU2015258110B2 (en) * | 2014-05-07 | 2019-06-20 | Boehringer Ingelheim International Gmbh | Nebulizer, indicator device and container |
EA032599B1 (en) * | 2014-05-07 | 2019-06-28 | Бёрингер Ингельхайм Интернациональ Гмбх | Nebulizer, indicator device and container |
EA032850B1 (en) * | 2014-05-07 | 2019-07-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Container, nebulizer and method of making a container |
AU2015257878B2 (en) * | 2014-05-07 | 2019-08-08 | Boehringer Ingelheim International Gmbh | Container, nebulizer and use |
US10576222B2 (en) | 2014-05-07 | 2020-03-03 | Boehringer Ingelheim International Gmbh | Container, indicator device with moveable piercing part, and nebulizer |
US10716906B2 (en) | 2014-05-07 | 2020-07-21 | Boehringer Ingelheim International Gmbh | Nebulizer and container |
US10716907B2 (en) | 2014-05-07 | 2020-07-21 | Boehringer Ingelheim International Gmbh | Nebulizer |
WO2015169732A1 (en) * | 2014-05-07 | 2015-11-12 | Boehringer Ingelheim International Gmbh | Container, nebulizer and use |
US10722666B2 (en) | 2014-05-07 | 2020-07-28 | Boehringer Ingelheim International Gmbh | Nebulizer with axially movable and lockable container and indicator |
AU2019203628B2 (en) * | 2014-05-07 | 2020-09-03 | Boehringer Ingelheim International Gmbh | Nebulizer, indicator device and container |
AU2019204569B2 (en) * | 2014-05-07 | 2020-11-05 | Boehringer Ingelheim International Gmbh | Nebulizer and container |
CN106456908A (en) * | 2014-05-07 | 2017-02-22 | 勃林格殷格翰国际有限公司 | Nebulizer, indicator device and container |
WO2015169431A3 (en) * | 2014-05-07 | 2015-12-30 | Boehringer Ingelheim International Gmbh | Nebulizer, indicator device and container |
IL247927B (en) * | 2014-05-07 | 2022-09-01 | Boehringer Ingelheim Int | Container, nebulizer and use |
EP4052747A1 (en) * | 2014-05-07 | 2022-09-07 | Boehringer Ingelheim International GmbH | Nebulizer, indicator device and container |
WO2022002993A1 (en) | 2020-07-03 | 2022-01-06 | Boehringer Ingelheim International Gmbh | Nebulizer |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2781792C (en) | Nebulizer | |
US11642476B2 (en) | Nebulizer | |
US10124125B2 (en) | Nebulizer | |
AU2017201521B2 (en) | Nebulizer | |
US9827384B2 (en) | Nebulizer | |
EP3030298B1 (en) | Nebulizer | |
AU2010323301B2 (en) | Nebulizer | |
US20120260913A1 (en) | Nebulizer | |
AU2015202524A1 (en) | Nebulizer | |
NZ614219B2 (en) | Nebulizer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 201080052884.5 Country of ref document: CN |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 10781681 Country of ref document: EP Kind code of ref document: A1 |
|
WWE | Wipo information: entry into national phase |
Ref document number: 219088 Country of ref document: IL |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2010323220 Country of ref document: AU |
|
ENP | Entry into the national phase |
Ref document number: 2010323220 Country of ref document: AU Date of ref document: 20101122 Kind code of ref document: A |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2010781681 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 12081916 Country of ref document: CO |
|
WWE | Wipo information: entry into national phase |
Ref document number: 000699-2012 Country of ref document: PE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2012540382 Country of ref document: JP Ref document number: MX/A/2012/005961 Country of ref document: MX |
|
ENP | Entry into the national phase |
Ref document number: 2781792 Country of ref document: CA |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1201002386 Country of ref document: TH Ref document number: 12012501039 Country of ref document: PH |
|
WWE | Wipo information: entry into national phase |
Ref document number: 4695/DELNP/2012 Country of ref document: IN |
|
WWE | Wipo information: entry into national phase |
Ref document number: A201207260 Country of ref document: UA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 201200775 Country of ref document: EA |
|
ENP | Entry into the national phase |
Ref document number: 20127016237 Country of ref document: KR Kind code of ref document: A |
|
WWE | Wipo information: entry into national phase |
Ref document number: 12763 Country of ref document: GE |
|
REG | Reference to national code |
Ref country code: BR Ref legal event code: B01A Ref document number: 112012012475 Country of ref document: BR |
|
ENP | Entry into the national phase |
Ref document number: 112012012475 Country of ref document: BR Kind code of ref document: A2 Effective date: 20120524 |