WO2008034924A1 - Method for obtaining human osseous implants in biocompatible materials - Google Patents

Method for obtaining human osseous implants in biocompatible materials Download PDF

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Publication number
WO2008034924A1
WO2008034924A1 PCT/ES2007/000522 ES2007000522W WO2008034924A1 WO 2008034924 A1 WO2008034924 A1 WO 2008034924A1 ES 2007000522 W ES2007000522 W ES 2007000522W WO 2008034924 A1 WO2008034924 A1 WO 2008034924A1
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WIPO (PCT)
Prior art keywords
interest
area
prototype
patient
virtual
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PCT/ES2007/000522
Other languages
Spanish (es)
French (fr)
Inventor
David Cano Sanz
Francisco Javier GARCÍA GÓMEZ
Marina DE LA FUENTE GÓMEZ
Alfredo SÁNCHEZ BUSTOS
Original Assignee
Trisermedin, S.L.
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Publication of WO2008034924A1 publication Critical patent/WO2008034924A1/en

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Classifications

    • G—PHYSICS
    • G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
    • G09B23/30—Anatomical models
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/38—Joints for elbows or knees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2875—Skull or cranium
    • A61F2002/2889—Maxillary, premaxillary or molar implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A61F2002/30948—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using computerized tomography, i.e. CT scans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A61F2002/30957—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using a positive or a negative model, e.g. moulds

Definitions

  • the present invention relates to a process for obtaining human bone implants in biocompatible materials.
  • the morphology of the implants is attempted by modeling the biocompatible material before polymerization. This causes in most cases aesthetic results far from the objective sought.
  • Another of the procedures used consists in the pre-selection of manufactured implants, the size of which approximates that required (hip, knee, malar prostheses, etc.). In this case, the aesthetic requirements sought are not achieved.
  • portions of bones from the tibia are usually used. CG ⁇ C can be inferred, - this type of intervention subjects the patient to new risks.
  • the process of the invention serves an optimal way to manufacture human bone implants.
  • SUBSTITUTE SHEET (RULE 26) customized in biocompatible materials, since it would not be necessary to manufacture or select them during the operation. The time, and therefore the costs, as well as the risk of the intervention are considerably reduced.
  • the invention also contemplates the manufacture of a model of the area of interest of the patient, in addition to the implant prosthesis itself, so that the doctor can plan and train the operation in advance. This cooperates in further reducing the time and costs of the intervention, improving aesthetic results and facilitating recovery.
  • another advantage associated with the invention is that, due to the possibility of being able to plan and train the intervention in advance, errors not previously detected can be detected and corrected, and that during the intervention it has a more compromised solution.
  • the process comprises the following steps:
  • -Get medical images of the area of interest of the patient This stage is carried out by various medical techniques known or that may be developed in the future, and typically by performing a computerized axial tomography and / or magnetic resonance imaging. -Processed by computer of the images obtained until a virtual reconstruction of the patient's area of interest is achieved.
  • This stage can materialize mainly in two ways: either through the virtual design of the prototype on the virtual reconstruction of the area of interest, and its subsequent physical modeling through rapid prototyping techniques; or by physical modeling by rapid prototyping techniques of the client's area of interest, and manual modeling on it
  • this manual modeling is done with materials that are deformable or flexible, and therefore, when making the final mold for the implant, its deformation could lead to inaccuracies or imperfections-
  • the invention contemplates the taking of images by computerized axial lathegraphy of the model obtained manually in deformable and / or flexible material and the computer processing of the images obtained, analogously as described in previous stages, to obtain a virtual design of the implant, and from it its modeling by Rapid prototyping techniques in materials of adequate consistency to resist mold fabrication.
  • the invention also contemplates the modeling by rapid prototyping techniques of the area of interest of the patient to train the operation or check the good fit of the implant obtained by the aforementioned procedures, directly by virtual reconstruction and rapid prototyping.
  • the process of the invention comprises the following steps:
  • SUBSTITUTE SHEET (RULE 26) to be corrected by the implant final result of the process of the invention.
  • These images can be obtained by any of the techniques known or that may be developed in the future, and typically by computerized axial tomography or magnetic resonance imaging.

Abstract

Method for obtaining human osseous implants in biocompatible materials, characterized in that it comprises the stages of: obtaining medical images of the area of interest of the patient, processing the images obtained using a computer until a virtual reconstruction of the area of interest of the patient is obtained, obtaining a physical prototype of the implant using rapid prototyping techniques in cooperation with the virtual reconstruction of the area of interest, obtaining the physical implant by means of moulding from a mould obtained from the prototype.

Description

PROCEDIMIENTO PARA OBTENER IMPLANTES ÓSEOS HUMANOS EN MATERIALES BIOCOMPATIBLES PROCEDURE FOR OBTAINING HUMAN BONE IMPLANTS IN BIOCOMPATIBLE MATERIALS
OBJETO DE LA INVENCIÓNOBJECT OF THE INVENTION
La presente invención se refiere a un procedimiento para obtener implantes óseos humanos en materiales biocompatibles .The present invention relates to a process for obtaining human bone implants in biocompatible materials.
ANTECEDENTES DE LA INVENCIÓNBACKGROUND OF THE INVENTION
En la actualidad, dentro del campo de la colocación de implantes, se emplean diversas técnicas:Currently, within the field of implant placement, various techniques are used:
Por ejemplo, en el caso de ciertas prótesis maxilofaciales, la morfología de los implantes se intenta conseguir mediante el modelado del material biocompatible antes de su polimerización. Esto ocasiona en la mayoría de los casos resultados estéticos lejos del objetivo buscado . Otro de los procedimientos utilizados consiste en la preselección de implantes fabricados, cuyo tamaño se aproxime al requerido (prótesis de cadera, rodilla, malares, etc.) . En este caso tampoco se consiguen los requerimientos estéticos buscados. Cuando la zona a reconstruir es muy amplia, se suelen utilizar porciones de huesos procedentes por ejemplo de la tibia. CGΓÍÍC se puede inferir,- este tipo de intervenciones somete al paciente a nuevos riesgos.For example, in the case of certain maxillofacial prostheses, the morphology of the implants is attempted by modeling the biocompatible material before polymerization. This causes in most cases aesthetic results far from the objective sought. Another of the procedures used consists in the pre-selection of manufactured implants, the size of which approximates that required (hip, knee, malar prostheses, etc.). In this case, the aesthetic requirements sought are not achieved. When the area to be rebuilt is very wide, portions of bones from the tibia are usually used. CGΓÍÍC can be inferred, - this type of intervention subjects the patient to new risks.
Todos estos inconvenientes se subsanan con la utilización del procedimiento de la invención.All these inconveniences are remedied with the use of the method of the invention.
DESCRIPCIÓN DE LA INVENCIÓNDESCRIPTION OF THE INVENTION
El procedimiento de la invención sirve una manera óptima para fabricar implantes óseos humanosThe process of the invention serves an optimal way to manufacture human bone implants.
HOJA DE SUSTITUCIÓN (REGLA 26) personalizados en materiales biocompatibles, ya que no sería necesario fabricarlos o seleccionarlos durante la operación. El tiempo, y por tanto los costes, así como el riesgo de la intervención se reducen considerablemente. Además la invención contempla igualmente la fabricación de un modelo de la zona de interés del paciente, además de la propia prótesis <~> implante, de forma que el médico puede planificar y entrenar la operación con antelación. Esto coopera en reducir aún más el tiempo v costes de la intervención, mejorar los resultados estéticos y facilitar la recuperación. Además, otra ventaja asociada a la invención es que, debido la posibilidad de poder planificar y entrenar la intervención con antelación, se pueden detectar y corregir errores no detectados previamente, y que durante la intervención tiene una solución más comprometida.SUBSTITUTE SHEET (RULE 26) customized in biocompatible materials, since it would not be necessary to manufacture or select them during the operation. The time, and therefore the costs, as well as the risk of the intervention are considerably reduced. In addition, the invention also contemplates the manufacture of a model of the area of interest of the patient, in addition to the implant prosthesis itself, so that the doctor can plan and train the operation in advance. This cooperates in further reducing the time and costs of the intervention, improving aesthetic results and facilitating recovery. In addition, another advantage associated with the invention is that, due to the possibility of being able to plan and train the intervention in advance, errors not previously detected can be detected and corrected, and that during the intervention it has a more compromised solution.
De acuerdo con la invención, el procedimiento comprenden las siguientes etapas:According to the invention, the process comprises the following steps:
-Obtener imágenes médicas de la zona de interés del paciente. Esta etapa se lleva a cabo mediante diversas técnicas médicas conocidas o que puedan ser desarrolladas en el futuro, y típicamente mediante la realización de una tomografía axial computerizada y/o resonancia magnética . -Procesado mediante ordenador de las imágenes obtenidas hasta conseguir una reconstrucción virtual de la zona interés del paciente.-Get medical images of the area of interest of the patient. This stage is carried out by various medical techniques known or that may be developed in the future, and typically by performing a computerized axial tomography and / or magnetic resonance imaging. -Processed by computer of the images obtained until a virtual reconstruction of the patient's area of interest is achieved.
-Obtención de un diseño o prototipo del implante. Esta etapa puede materializarse principalmente de dos formas: o bien mediante el diseño virtual del prototipo sobre la reconstrucción virtual de la zona de interés, y su posterior modelado físico mediante técnicas de prototipado rápido; o bien mediante el modelado físico mediante técnicas de prototipado rápido de la zona interés del cliente, y el modelado manual sobre ésta-Getting a design or prototype of the implant. This stage can materialize mainly in two ways: either through the virtual design of the prototype on the virtual reconstruction of the area of interest, and its subsequent physical modeling through rapid prototyping techniques; or by physical modeling by rapid prototyping techniques of the client's area of interest, and manual modeling on it
HOJA DE SUSTITUCIÓN (REGLA 26) reproducción de la zona de interés del prototipo. También pueden combinarse estas dos formas de trabajar.SUBSTITUTE SHEET (RULE 26) Reproduction of the area of interest of the prototype. These two ways of working can also be combined.
En algunos casos este modelado manual se realiza con materiales que son deformables o flexibles, y que por lo tanto a la hora de confeccionar el molde definitivo para el implante su deformación podría originar imprecisiones o imperfecciones- En estos casos la invención contempla la toma de imágenes mediante tornografia axial computerizada del modelo obtenido manualmente en material deformable y/o flexible y el procesado mediante ordenador de las imágenes obtenidas, análogamente a como se ha descrito en etapas anteriores, para obtener un diseño virtual del implante, y a partir de éste su modelado por técnicas de prototipado rápido en materiales de consistencia adecuada para resistir la fabricación del molde.In some cases this manual modeling is done with materials that are deformable or flexible, and therefore, when making the final mold for the implant, its deformation could lead to inaccuracies or imperfections- In these cases the invention contemplates the taking of images by computerized axial lathegraphy of the model obtained manually in deformable and / or flexible material and the computer processing of the images obtained, analogously as described in previous stages, to obtain a virtual design of the implant, and from it its modeling by Rapid prototyping techniques in materials of adequate consistency to resist mold fabrication.
En cualquier caso, la invención también contempla el modelado por técnicas de prototipado rápido de la zona de interés del paciente para entrenar la operación o comprobar el buen ajuste del implante obtenido por los procedimientos anteriormente mencionados, directamente por reconstrucción virtual y prototipado rápido.In any case, the invention also contemplates the modeling by rapid prototyping techniques of the area of interest of the patient to train the operation or check the good fit of the implant obtained by the aforementioned procedures, directly by virtual reconstruction and rapid prototyping.
-Obtención del implante físico a partir del prototipo obtenido según la etapa anterior, realizando un molde sobre éste, y generando en el molde la prótesis o implante definitivo.-Getting the physical implant from the prototype obtained according to the previous stage, making a mold on it, and generating in the mold the definitive prosthesis or implant.
-Esterilización de la prótesis o implante conseguido .-Sterilization of the prosthesis or implant achieved.
DESCRIPCIÓN DE UNA REALIZACIÓN PRACTICA DE LA INVENCIÓNDESCRIPTION OF A PRACTICAL EMBODIMENT OF THE INVENTION
El procedimiento de la invención comprenden las siguientes etapas:The process of the invention comprises the following steps:
1. obtener una imagen médica de la zona de interés del paciente, en la cual se localiza el defecto que hay1. obtain a medical image of the area of interest of the patient, in which the defect is located
HOJA DE SUSTITUCIÓN (REGLA 26) que subsanar mediante el implante resultado final del procedimiento de la invención. Estas imágenes se pueden obtener por cualquiera de las técnicas conocidas o que se puedan desarrollar en el futuro, y típicamente mediante tomografia axial computerizada o resonancia magnética.SUBSTITUTE SHEET (RULE 26) to be corrected by the implant final result of the process of the invention. These images can be obtained by any of the techniques known or that may be developed in the future, and typically by computerized axial tomography or magnetic resonance imaging.
2. procesar las imágenes obtenidas mediante computadora hasta obtener una reconstrucción virtual de la zona interés del paciente.2. process the images obtained by computer until a virtual reconstruction of the patient's area of interest is obtained.
3. obtener un prototipo del implanLe. Esta etapa ≤e puede materializar de dos formas:3. Obtain a prototype of the implanLe. This stage ≤e can materialize in two ways:
-mediante el diseño virtual del implante utilizando técnicas informáticas, según las cuales por ejemplo se puede obtener el diseño de una parte ósea desaparecida como réplica especular de su simétrica en la propia anatomía del paciente. A partir del diseño virtual, y mediante técnicas de prototipado rápido con la participación de maquinaria adecuada, se obtiene el prototipo físico.-through the virtual design of the implant using computer techniques, according to which for example the design of a missing bone part can be obtained as a mirror replica of its symmetric in the patient's own anatomy. From the virtual design, and through rapid prototyping techniques with the participation of suitable machinery, the physical prototype is obtained.
-En casos complejos, mediante la fabricación por prototipado rápido de una reproducción de la zona de interés del paciente, ya que está capturada en el ordenador, y la fabricación manual sobre ésta de un modelo de la prótesis, que si se realiza en materiales consistentes podría constituirse en el prototipo definitivo. No obstante lo cual, y dado que este modelo manual muchas veces se realiza en materiales deformables no susceptibles ue mantener su forma en la fabricación del molde, en estos casos es necesario realizar una tomografia axial computerizada de este modelo consiguiendo su captura virtual, y a partir de esta captura obtener el prototipo definitivo en materiales de consistencia adecuada utilizando técnicas de prototipado rápido .-In complex cases, through the rapid prototyping of a reproduction of the area of interest of the patient, since it is captured in the computer, and the manual manufacture on it of a model of the prosthesis, which if done in consistent materials It could become the definitive prototype. However, and since this manual model is often made of deformable materials that are not susceptible to maintaining its shape in the manufacture of the mold, in these cases it is necessary to perform a computerized axial tomography of this model getting its virtual capture, and from from this capture obtain the definitive prototype in materials of adequate consistency using rapid prototyping techniques.
4. obtener el implante fisico, realizando en primer lugar un molde de colada a partir del prototipo, y4. obtain the physical implant, first of all making a casting mold from the prototype, and
HOJA DE SUSTITUCIÓN (REGLA 26) después moldeando el implante definitivo.SUBSTITUTE SHEET (RULE 26) then molding the definitive implant.
5. esterilizar el implante obtenido, con lo cual estará preparado para su implantación en el paciente.5. Sterilize the implant obtained, which will be prepared for implantation in the patient.
Descrita suficientemente la naturaleza de la inven-Describe the nature of the invention sufficiently
5 ción, asi como la manera de realizarse en la práctica, debe hacerse constar que las disposiciones anteriormente indicadas son susceptibles de πnodificaciones de detalle en cuanto no alteren el principio fundamental.In addition, as well as the way in which it is carried out in practice, it should be noted that the provisions indicated above are subject to detailed modifications as long as they do not alter the fundamental principle.
1010
15fifteen
20twenty
2525
JUJU
3535
HOJA DE SUSTITUCIÓN (REGLA 26) SUBSTITUTE SHEET (RULE 26)

Claims

REIVINDICACIONES
1. -procedimiento para obtener implantes óseos humanos en materiales biocompatibles; caracterizado porque comprende las etapas de:1. -procedure to obtain human bone implants in biocompatible materials; characterized in that it comprises the stages of:
-Obtener imágenes médicas de la zona interés del-Get medical images of the area of interest of the
-Procesar las imágenes obtenidas informáticamente hasta conseguir una reconstrucción virtual de la zona interés del paciente.-Process the images obtained by computer until a virtual reconstruction of the patient's area of interest is achieved.
-Obtener un prototipo físico del implante utilizando técnicas de prototipado rápido en cooperación con la reconstrucción virtual de la zona de interés.-Get a physical prototype of the implant using rapid prototyping techniques in cooperation with the virtual reconstruction of the area of interest.
-Obtener el implante físico por moldeo a partir de un molde obtenido sobre el prototipo.-Get the physical implant by molding from a mold obtained on the prototype.
-Esterilizar el implante obtenido.-Sterilize the implant obtained.
2. -Procedimiento según reivindicación 1 caracterizado porque la obtención de imágenes médicas se realiza preferentemente por tomografía axial computerizada y/o resonancia magnética.2. Procedure according to claim 1 characterized in that the medical imaging is preferably performed by computerized axial tomography and / or magnetic resonance imaging.
3. -Procedimiento según reivindicación 1 caracterizado porque la obtención del prototipo físico se realiza mediante su modelado virtual directamente en la reconstrucción virtual de la zona de interés del paciente, y su materialización por técnicas de prototipado rápido.3. Procedure according to claim 1 characterized in that the obtaining of the physical prototype is carried out by means of its virtual modeling directly in the virtual reconstruction of the area of interest of the patient, and its materialization by rapid prototyping techniques.
4. -Procedimiento según reivindicación 1 caracterizado porque en casos complejos la obtención del prototipo se realiza mediante su modelado manual sobre una reproducción de la zona de interés del paciente obtenida por técnicas de prototipado rápido.4. -Procedure according to claim 1 characterized in that in complex cases the obtaining of the prototype is performed by manual modeling on a reproduction of the area of interest of the patient obtained by rapid prototyping techniques.
5. -Procedimiento según reivindicación 4 caracterizado porque en casos donde el modelado manual sobre la reproducción de la zona interés se realice en materiales deformables durante la fabricación del molde,5. -Procedure according to claim 4 characterized in that in cases where manual modeling on the reproduction of the area of interest is performed on deformable materials during the manufacture of the mold,
HOJA DE SUSTITUCIÓN (REGLA 26) se realiza una tomografía axial computarizada de dicho modelado para obtener una captura virtual del mismo, y a partir de la misma la obtención del prototipo en materiales de consistencia adecuada utilizando técnicas de prototipado rápido.SUBSTITUTE SHEET (RULE 26) a computerized axial tomography of said modeling is performed to obtain a virtual capture of the same, and from it obtaining the prototype in materials of adequate consistency using rapid prototyping techniques.
6. -Procedimiento según reivindicación 3 caracterizado porque PΠ el modelado virtual del prototipo para implantes destinados a reparar zonas óseas desaparecidas se replica especaiariTiente Ia parte simétrica de la anatomía del paciente.6. Procedure according to claim 3 characterized in that PΠ the virtual modeling of the prototype for implants intended to repair missing bone areas is replicated specaiariTiente the symmetrical part of the patient's anatomy.
HOJA DE SUSTITUCIÓN (REGLA 26) SUBSTITUTE SHEET (RULE 26)
PCT/ES2007/000522 2006-09-18 2007-09-18 Method for obtaining human osseous implants in biocompatible materials WO2008034924A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200602364A ES2294941B1 (en) 2006-09-18 2006-09-18 PROCEDURE FOR OBTAINING HUMAN BEAR IMPLANTS IN BIOCOMPATIBLE MATERIALS.
ESP200602364 2006-09-18

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