CN103635807A - Sample evaluation result reporting after queuing the result for transmission - Google Patents

Sample evaluation result reporting after queuing the result for transmission Download PDF

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Publication number
CN103635807A
CN103635807A CN201280032988.9A CN201280032988A CN103635807A CN 103635807 A CN103635807 A CN 103635807A CN 201280032988 A CN201280032988 A CN 201280032988A CN 103635807 A CN103635807 A CN 103635807A
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pathogen
experimenter
biological specimen
benefit
assessment
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Inventor
埃雷兹·利伯曼·艾丹
迈克尔·H·贝姆
罗德里克·A·海德
乔丁·T·卡勒
伊丽莎白·A·斯威尼
小洛厄尔·L·伍德
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Searete LLC
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Searete LLC
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Priority claimed from US13/068,295 external-priority patent/US20120284047A1/en
Priority claimed from US13/068,297 external-priority patent/US20120284048A1/en
Priority claimed from US13/068,291 external-priority patent/US20120284046A1/en
Priority claimed from US13/068,301 external-priority patent/US20120284049A1/en
Priority claimed from US13/068,298 external-priority patent/US20120284037A1/en
Priority claimed from US13/068,296 external-priority patent/US20120283138A1/en
Application filed by Searete LLC filed Critical Searete LLC
Publication of CN103635807A publication Critical patent/CN103635807A/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

A system or device includes an evaluation module for automatically evaluating, remotely from a health care facility, a biological sample acquired from a subject for a presence or an absence of at least one pathogen in the biological sample; an electronic memory for queuing a first result of the evaluation for transmission to an off-site entity; and a reporting module for reporting a second result of the evaluation to the subject after queuing the first result of the evaluation for transmission.

Description

Sample assessment results report after the result for transmitting is queued up
Summary of the invention
In one aspect, a kind of method includes but not limited to from a health care facility gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess this biological specimen; This assessment first result is carried out to electric queuing and for being transferred to an entity outside the venue; And this first result of this assessment is ranked for second report the test of this assessment being given after transmitting to this experimenter.In addition to the foregoing, in having formed claims, accompanying drawing and the word of the part of this disclosure, described aspect additive method.
In one or more different aspects, a plurality of related systems include but not limited to for realizing circuit and/or the programming aspect the method for quoting at this; Depend on the design alternative of system designer, in fact this circuit and/or programming can be to be configured for any combination that realizes hardware, software and/or firmware aspect the method quote at this.
In one aspect, system includes but not limited to: an evaluation module, this evaluation module for from a health care facility to gathering a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess at this biological specimen; An electronic memory, this electronic memory is for ranking and for being transferred to an entity outside the venue to this assessment first result; And a reporting modules, this report module for this first result of this assessment is ranked for transmission after by second report the test of this assessment to this experimenter.In addition to the foregoing, in having formed claims, accompanying drawing and the word of the part of this disclosure, described aspect other system.
In one aspect, device includes but not limited to: an evaluation module, this evaluation module for from a health care facility to gathering a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess at this biological specimen; An electronic memory, this electronic memory and this evaluation module couple for this assessment first result is ranked for being transferred to an entity outside the venue; And a reporting modules, this report module and this evaluation module couple for this first result of this assessment is ranked for second report the test of this assessment being given after transmitting to this experimenter.In addition to the foregoing, in having formed claims, accompanying drawing and the word of the part of this disclosure, described aspect other system.
In one aspect, computer program includes but not limited to: instantaneous a, signal bearing medium recordable type, non-, and this medium carrying is configured for remotely from a health care facility and causes gathering a biological specimen from an experimenter for whether there is the computer usable code of the automatic evaluation of at least one pathogen this biological specimen; Be configured for this assessment first result is carried out to electric queuing and for being transferred to a computer usable code for entity outside the venue; And be configured for this first result of this assessment is ranked for after transmitting by second report the test of this assessment the computer usable code to this experimenter.
In addition to the foregoing, for example, in the text (, claims and/or detailed description) of for example this disclosure and/or teaching middle statement and having described different additive methods and/or system and/or program product aspect of accompanying drawing.
Aforementioned content is a summary, and therefore can comprise details simplification, summarize, comprise and/or omit; Therefore, those skilled in the art will recognize, this summary is only illustrative and is not intended to limit by any way.Other aspects, feature and the advantage of device described here and/or process and/or other themes is by become obvious in the teaching of this statement.
Brief Description Of Drawings
Fig. 1 is a schematic diagram.
Fig. 2 illustrates an operating process of showing a plurality of exemplary operations.
Fig. 3 illustrates an alternate embodiment of the operating process of Fig. 2.
Fig. 4 illustrates an alternate embodiment of the operating process of Fig. 2.
Fig. 5 illustrates an operating process of showing a plurality of exemplary operations.
Fig. 6 illustrates an operating process of showing a plurality of exemplary operations.
Fig. 7 illustrates an operating process of showing a plurality of exemplary operations.
Fig. 8 illustrates an operating process of showing a plurality of exemplary operations.
Fig. 9 illustrates an operating process of showing a plurality of exemplary operations.
Figure 10 illustrates an operating process of showing a plurality of exemplary operations.
Figure 11 illustrates an alternate embodiment of the operating process of Fig. 8.
Figure 12 illustrate to this result is ranked for a computer program reporting after transmitting that an assessment result of a sample is relevant.
Describe in detail
In the following detailed description, the accompanying drawing that forms a part herein with reference to these.In the accompanying drawings, similarly symbol typically represents and indicates similar assembly, unless context is stipulated in addition.These illustrative examples described in describing in detail, accompanying drawing and claim not meaning that limits.Do not departing from the situation that this theme tone presenting or scope can be utilized other embodiment, and can make other changes.
Prior art proceeded between hardware, software and/or the firmware implementation of the many aspects of a plurality of systems, remain minimum difference a bit; The use of hardware, software and/or firmware substantially (but not always, because in some context, the selection between hardware and software may become important) is the compromise design alternative of displaying expense to efficiency.The different instruments that existence can realize a plurality of process described here and/or system and/or other technologies (for example, hardware, software and/or firmware), and preferred instrument changes the context with having disposed these processes and/or system and/or other technologies.For example, if executor determines speed and accuracy, be most important, this executor can select a main hardware and/or firmware medium so; Alternately, if dirigibility is most important, this executor can select a main software realization mode so; Or again alternately, this executor can select some combination of hardware, software and/or firmware.Therefore, there is some possible medium, process described herein and/or device and/or other technologies may be subject to these vectorial impacts, any one in them is not better than another in itself, this is because the medium that needs arbitrarily to be utilized is all to depend on a following selection: medium by the environment being deployed and executor's concrete focus (for example, speed, dirigibility or predictability), any in them all may change.Hardware, software and/or the firmware of optics guiding will typically be used in a plurality of optics aspect of a plurality of implementations.
In some implementation described here, logic and similarly implementation can comprise software or other control structures.Electronic circuit for example can have and is configured to and is arranged to realize one or more current paths of difference in functionality as described in this.In some implementations, as described in this, one or more media can be configured to carry a kind of equipment when these media keep or transmission can move to realize a equipment can detect instruction can detect implementation.In some variant, for example, implementation can comprise as upgraded or revise existing software or firmware or gate array or programmable hardware by carrying out the reception of one or more instructions relevant to one or more operations described here or transmitting.Alternately or extraly, in some variant, a kind of implementation can comprise specialized hardware, software, fastener components and/or operation or otherwise call the general purpose module of personal module.Standard or other implementations can be transmitted by one or more examples of tangible as described in this transmission medium, alternatively by data packet transmission or otherwise transmit by distributed medium in the different time.
Alternately or extraly, implementation can comprise carry out a special instruction sequence or call circuit enable, trigger, coordinate, ask or otherwise cause at this, described almost arbitrarily the one or many of feature operation occur.In some variant, maneuverability herein or other logicalities are described and can be shown as source code and be compiled, or otherwise as executable instruction sequence, call.In some cases, for example, implementation can all or part ofly be provided as source code, for example C++ or other code sequences.In other implementations, use the commercially available and/or technology in this area source code or other code implementations (for example can be compiled/implement/translate/be converted to senior descriptor language, by C or C++ programming language, implement described technology at first, then, this program language implementation is converted to the expression of a logic synthesis language implementation, hardware description language implementation, hardware design the Realization of Simulation mode and/or other one or more such similar fashion).For example, some or all logical expressions (for example, computer programming language implementation) can be expressed as a kind of Verilog type of hardware (for example describes, by hardware description language (HDL) and/or very high speed IC hardware description (VHDL)) or other can be used for creating the circuit model for example, with hardware (, a kind of special IC) of a physics realization mode.According to these instructions, how those of ordinary skill in the art obtains, configures and optimizes suitable transmitter or computing element, material supply, actuator or other structure by recognizing.
With reference now to Fig. 1,, a kind of for assessment of the system with report biological specimen according to the invention describes.This system comprises an evaluation module 110, electronic memory 120, transport module 130, reporting modules 140 or a benefit module 150 optionally.In an implementation, comprise that evaluation module 110, electronic memory 120, transport module 130 and reporting modules 140 are as a triangular web 100.In an implementation, provide evaluation module 110 as single device, and provide electronic memory 120, transport module 130 and reporting modules 140 as another device.In an implementation, comprise that electronic memory 120 and transport module 130 are as single device, and comprise that reporting modules 140 is as another device.Can comprise personal computer, laptop computer, palmtop computer, PDA(Personal Digital Assistant), mobile phone or image capture apparatus, for example digital camera with the device inventory of the non-limit utilizing together with this disclosure.It should be noted that this inventory only provides by way of example, and other different devices can utilize with together with this disclosure.Further, comprise that the different device that different functionalities combines can be used to realize for evaluation module 110, electronic memory 120, transport module 130, reporting modules 140 or the described different functionalities of benefit module 150.For example, system 100 comprises an evaluation module 110, electronic memory 120, transport module 130, reporting modules 140 and a benefit module 150.
Include the evaluation module 110 of system 100 for this biological specimen automatically being assessed to determine whether one or more pathogen are present in experimenter.For example, these one or more pathogen can comprise virus (for example, one or more in human immunodeficiency virus (HIV), parasitic animal and plant, bacterium, fungi, toxin or toxigenic pathogen.Additionally, these one or more pathogen can comprise for example one or more in influenza A virus, subtypes of influenza A virus, influenza B virus or influenza virus C etc. of influenza virus.For example, evaluation module 110 can detect in this biological specimen, whether there is a kind of pathogen.As used herein, term " pathogen " comprises that pathogen self or pathogen are present in the one or more indications in experimenter.Pathogen this type of indication in experimenter comprise from this pathogen and a kind of antigen this pathogen homology, with the immunoreactive antibody of this pathogen, chemicals, toxin, nucleic acid, pathogen associated molecular pattern (PAMP) or the analog relevant with the existence of pathogen.Nucleic acid can obtain from or be found in the polynucleotide passage of DNA, RNA or a pathogen from the polynucleotide passage of DNA, RNA or a kind of pathogen.For example, a concrete DNA sequence dna can be associated with a pathogen.In another example, a unmethylated nucleic acid (CpG) can be associated with a kind of bacterial pathogen.Further, double-stranded RNA can be associated with a kind of viral pathogens.PAMP can comprise the flagellin of bacterial flagellum, the lipopolysaccharides of the peptide glycan of gram-positive bacterium, gramnegative bacterium (LPS or endotoxin), lipoteichoicacid (LTA) gram-positive bacterium, double-stranded RNA or unmethylated DNA.Additionally, evaluation module 110 can directly detect in this sample, whether there are one or more pathogen.
An experimenter provides a biological specimen to supply evaluation module 110 assessments.Can remotely gather this sample from a health care facility.Further, evaluation module 110 remotely provides the automatic evaluation to this biological specimen from a health care facility.In the context of this disclosure, one " health care facility " comprises any position, wherein carry out biological specimen assessment, or wherein experimenter is the biopathogen body being exposed to from people or environmental factor, these biopathogen bodies in the unconnected house type environment of Yu group healthcare activities conventionally, find those outside.The health care facility inventory of a non-limit will comprise hospital, outpatient clinic, emergency treatment clinic and Physical Examination Center and diagnostic test chamber.In one embodiment, sample comprises one or more in following content: biological specimen, for example, via fluid, cell or tissue that for example nasal cavity swab, buccal swab, thoracic cavity swab obtain, nasal cavity extract, oral cavity extract, thoracic cavity extract, nasal cavity cleaning liquid, oral cavity cleaning fluid, thoracic cavity cleaning fluid, tissue/skin scraping thing, mucus, phlegm, saliva, urine, or blood etc.In a plurality of embodiment, evaluation module 110 can comprise one or more in following content determine in a sample, whether there are one or more pathogen: test strips, " chip lab (lab-on-a-chip) " device, measure (for example, microelectromechanical systems/microelectronics and microelectromechanical systems (MEMS) biometric apparatus), effluent test strips, Colorimetric test paper bar, effluent Colorimetric test paper bar, through skin proving installation or lancet etc.
In one embodiment, a Colorimetric test paper bar can be based on aptamer (aptamer).That nucleic acid aptamer of homologue of a target analytes is by conjugation to bar or card.In conjunction with time, this test strips changes color, this easily detects.Other embodiment comprise the Colorimetric test paper bar that uses antibody conjugates, the shunting parasite plate (Triage Parasite Panel) of for example being developed by U.S. Biosite Inc. (Biosite Diagnostics) (Diego California, California).
Figure BDA0000451965250000061
bar is single immunochromatography (IC) bar with monoclonal antibody coating, and these monoclonal antibodies are for 29-kDa surface antigen (E.histolytica-E.dispar), α-1-giardin(G.lamblia) and protein disulfide isomerase (C.parvum) be special.When this antibody conjugates (alkaline phosphatase) reacts with substrate (indoles acyl phosphate (indoxyl phosphate)), positive reaction in Triage kit is identified by a chrominance response qualitatively, thereby causes one on this IC bar dark blue purple line that can easily detect.
In one embodiment, evaluation module 110 comprises an effluent test strips.This effluent test strips comprises a sample pad substantially---this test sample book is applied to an absorption pad on it; conjugate or reagent pad; comprise the special antibody of pathogen to coloured particulate (typically, these particulates can comprise golden particulate or latex microsphere) for conjugation.What also comprise is a kind of reaction film, typically a kind of hydrophobic nitrocellulose or cellulose acetate membrane, antipathogen antibody using one across the line of this film, be immobilized on this film as trapping region or p-wire (can also have a control zone, comprising for these conjugate antibody is special antibody); Cotton core or waste liquid pool---be designed to attract sample across this reaction film and collect an other absorption pad of this sample by capillary.A plurality of ingredients of effluent test strips are fixed to a kind of inertia gasket material and can or present in a plastic casing with a kind of simple dipstick (dipstick) form, and this plastic casing has sample port and the reaction window that shows trapping region and control zone.
An example of an effluent test strips comprises double-antibody sandwich mensuration.This biological specimen migration is by conjugation pad, and any pathogen wherein existing is in connection with to this conjugate.This pathogen: conjugate complex compound then continues migration across this film until it arrives trapping region, wherein this pathogen: conjugate complex compound is in connection with to immobilized antibody, thereby produces a visible and detectable line on this film.This sample is then along this further migration, until it arrives control zone, wherein excessive conjugate will be on this film in conjunction with and produce a second visible and detectable line.This control line has indicated this sample if desired migration is across this film.On this film two clearly line be a positive findings.A single line in this control zone is a negative findings.Double-antibody sandwich is measured the larger analyte that is suitable for having a plurality of antigen sites, for example, without limitation, bacterial pathogen and virus.
Competitive assay utilizes a conjugation pad, and this conjugation pad comprises the antibody that is attached to interested pathogen.If this pathogen is present in this biological specimen, therefore this pathogen will not be combined with this conjugate and will remain unlabelled.At this sample, along the migration of this film and while arriving trapping region, too much unlabelled pathogen, in connection with to these immobilized antibody and stop catching of this conjugate, makes not produce visible line like this.Unconjugated conjugate is these antibody that are then bonded in this control zone, thereby produces a visible control line.A single control line on this film is a positive findings.Two visible lines in He Gai control zone, this trapping region are negative findingses.Yet, if too much unlabelled pathogen does not exist, can in this trapping region, produce a faint line so, thereby indicate a uncertain result.Competitive assay is suitable for the little molecule that test can not side by side be bonded to an above antibody, for example mycotoxin most.In lateral flow technology, have the variation of many routines, these variations comprise within the scope of the invention.Trapping region on this film can comprise immobilized antigen or enzyme, and this depends on target analytes and non-antibody.In one embodiment, a plurality of trapping regions are used for producing a multi-use test paper bar.For example, developed the commercial test strips that can detect dividually enterohemorrhagic Escherichia coli shiga toxin (EHEC Shiga toxin) ST1 and ST2 in same sample.
Current immunity detecting produced a result conventionally in 15 minutes.The degree that the amount that is bonded to the conjugate of this trapping region by measurement obtains quantification is possible.This can measure the intensity of coloured p-wire and complete with a dialectic sensors.For example ，Niu Qin company (NeogenCorporation) has developed Accuscan tMeffluent reader and its scope
Figure BDA0000451965250000081
measure kit and use together, and CharmSciences is also it
Figure BDA0000451965250000082
the mycotoxin test strips of scope is supplied a kind of reader.For example use the other technologies of the conjugate of fluorochrome label can improve the quantitative potential of lateral flow assays.
An embodiment comprises an evaluation module 110, and this evaluation module comprises a plurality of lab-on-chip devices.Referring to such as people such as Shu Erci (Schulze), bio-photon term periodical (JBiophotonics.), the 2nd the 4th phase of volume of April in 2009: 199-211 page, it is combined in this by reference.An embodiment can comprise peptide nanotube sensor, such as in Publication about Document, describe those: the people such as de la Rica, the international version of applied chemistry (AngewandteChemie International Edition), the 47th the 50th phase of volume, 9752-9755 page, in Dec, 2008, it is combined in this by reference.This type of peptide nanotube sensor is utilized and a pair of gold electrode that is coated with the peptide nanotube bridge joint of antibody.These nanotubes are concentrated pathogen in its surface by the molecular recognition between antibody and pathogen.These nanotubes are applicable to allow extremely responsive impedance (impedimetric) detection to pathogen in electric field line distribution.
An embodiment comprises an evaluation module 110, and this evaluation module comprises a lab-on-chip devices, and this device is used the scattering measuring to immune agglutination (immunoagglutination).Referring to for example " for the chip lab of field coil determination: the long-time stability of reagent and automatic sampling system ", laboratory automation association periodical (Journal of the Association for Laboratory Automation), the 15th volume, the 3rd phase, 216-223 page, it is combined in this by reference.
An embodiment comprises an evaluation module 110, and this evaluation module comprises one or more sensors, and these one or more sensors comprise that a biomolecule catches layer.This biomolecule is caught layer can comprise a collection of different binding molecule, and these binding molecules are particularly in conjunction with one or more target molecules (pathogen).For example, in one embodiment, these one or more sensors comprise a collection of microcell, and these microcells are modified to catch pathogen.In one embodiment, these one or more sensors comprise that one or more surface plasma resonance sensors are for detecting the pathogen of catching.For example, the sensor based on surface plasma body resonant vibration detects and is suspended in the pathogen in a kind of liquid, and its mode is for leaving by light reflection the metallic film contacting with this liquid.Absorption molecule causes the change of local indexes of refraction, thereby causes the detectable change of the resonant condition of surface plasma wave.
In one embodiment, evaluation module 110 can comprise a test strips, this test strips has a chemical sensor, measurements determination, maybe can determine the instrument of any other type whether pathogen exists, for example, for carrying out the instrument of a biochemical measurement.In one embodiment, user can provide a biological specimen for evaluation module 110 assessments to gatherer.In one embodiment, evaluation module 110 separates with gatherer.For example, user can provide a biological specimen to gatherer (for example,, for collecting the cup of urine); User can then test strips be inserted this for assessment of biological specimen in.In one embodiment, gatherer can be incorporated in evaluation module 110.For example, evaluation module 110 can comprise one family health promoting appliance.User can provide a biological specimen and this gatherer is inserted in family health care utensil for assessment to gatherer.
In one embodiment, evaluation module 110 can comprise a unique identifier.This unique identifier can comprise one or more in bar code, RFID label or wireless identification tag.In a plurality of embodiment, this unique identifier can be indicated one or more in following content: the time or evaluation module 110 types that between lot number, group's assignment (group assignment), the position, the position of report, the date of the date of acquisition, report, the date of acquisition and the date of report that obtain, pass.
In one embodiment, evaluation module 110 can be stored in the information with whether existing at least one pathogen to be associated in this biological specimen in electronic memory 120, for storing or be transferred to an entity 160 outside the venue.Can be with the storage of a kind of coded format and the information that whether exists at least one pathogen to be associated.Entity 160 can be one or more in medical provider, NSF, ,Huo insurance institution of government organs outside the venue.For example and without limitation, entity 160 can be at least one in the following outside the venue: CDC (CDC), the health of (FEMA) ,Huo You U.S. government of federal contingency management administration operation and a federal agency in public service portion.
In one embodiment, in supervision communicable disease, propagate while comprising supervision emerging infectious disease (EID), can be arranged by entity 160 outside the venue with the information that whether exists at least one pathogen to be associated.This type of information can be used to the disease in Monitoring Population and obtain about illness outbreak and popular information.EID can comprise by the infectious disease of the disease that causes of bacterial strain of the identification recently of the microorganism recently identifying or known microorganisms, the multiple new infectious disease being caused by a kind of existing zoic change or evolution, a kind of known infectious disease that extends to a new geographic area or colony, a kind of identification recently in the region of an experience Ecological Transformation or the infectious disease that be pre-existing in and identification that occurs once again because the resistance to the action of a drug or public health worsen.Further, outside the venue entity 160 can monitor disadvantageous Synergistic interaction between new disease and with cause other infectiousness of development of novel concurrent epidemic disease (syndemics) and the reciprocation of non-infectious illness, wherein the reciprocation between disease can make the health effect aggravation of disease.
Evaluation module 110 can provide one or more test results, for example, whether has first result of pathogen in indication sample.Can or report to experimenter or user by this first readout of assessment.This first result can be conveyed to this experimenter or user fully, or pass in a kind of limited mode.Further, in one embodiment, can utilize Fuzzy Processing to pass on this first result to prevent from conveying to non-user or non-experimenter.In one embodiment, fuzzy form can comprise one or more in coded format, alphanumeric code, image or password form.Further, the information with whether existing at least one pathogen to be associated in sample can be stored in electronic memory 120 as a first fuzzy result of assessing.In one embodiment, can in electronic memory 120, to the first result of assessment, rank for being transferred to subsequently entity 160 outside the venue.
In one embodiment, in this sample of the indication of this assessment, whether exist this first result of pathogen can be with respect to a value, threshold value, one or more and definite in many threshold values perhaps.For example, the designator that the existence of pathogen can surpass a threshold value by measurement is determined.Alternately, the existence of pathogen can be by determining with respect to a plurality of designators of a pathogen of many threshold measurements, and wherein, each designator can be measured with respect to one or more threshold values.Further, can determine and in this sample, not have pathogen in a kind of similar mode.
This experimenter or user (both use convertibly at this) can start this first result of this assessment to the transmission of entity 160 outside the venue.Alternately, system 100 can automatically be transferred to this first result of this assessment entity 160(outside the venue and for example, utilize a transport module 130).Transport module 130 can transmit via wired connection, wireless signal, digital signal, radio-frequency (RF) identification (RFID) label signal, communication network or wireless identification tag signal this first result of this assessment.For example, system 100 can comprise to for example connection of internet or cellular phone network of interconnection network.In one embodiment, system 100 can be transferred to this first result of this assessment the outer entity of an intermediate field for entity 160 access outside the venue.For example, system 100 can be posted to this result on a website or database, and then entity 160 can access this website or database and retrieve this result outside the venue.In one embodiment, system 100 comprises a transport module 130, and this transport module may be embodied as a network interface for promoting the connection to this network.Can utilize this network interface that this first result is transferred to entity 160 outside the venue.Alternately, the form of the bar code that this first result can be produced with a result based on test sample offers user, and user can read electronically this bar code or make its imaging and then by from reading this bar code or making its imaging and the communication that produces for example, utilizes this network interface etc. to entity 160(outside the venue).
Further, system 100 (for example can comprise a flash drive, in the situation that flash drive comprises an evaluation module 110), and can utilize a network interface, by this flash drive, this first result is transferred to entity 160 outside the venue, this flash drive can comprise that this network interface or this network interface can be to comprise the personal computer of a network interface and addressable by this flash drive is connected to.In this example, this flash drive and/or computing machine play transport module 130.Further, this first result can be offered to user with the form of alphanumeric code, and this user can for should alphanumeric code (for example, utilize keypad, phonetic entry or text message to send etc.) and this alphanumeric code is transferred to entity 160(outside the venue for example, utilizes this network interface etc.).
This of this assessment the first result can comprise about some personal information of this experimenter or not comprise the personal information about this experimenter.The all or part of of this experimenter's personal information can be supplied by the supplier of this experimenter, health care provider, this system or device.For example, personal information can comprise one or more in following content: extensive, the biologicall test proof of identification of experimenter's sex, experimenter's name, name, database pointer symbol, consensus data, experimenter's age are, experimenter's family, experimenter's position or experimenter's race.In one embodiment, this experimenter can select the anonymization degree of this personal information.For example, this experimenter can select to be identified as a member of one family, the resident of resident ,Yi Ge community of the resident in an address, a street or the resident in a city etc.This personal information can be taked the form of alphanumeric reference identification for example or digital reference sign.
The personal information of some types can determine via identification designator by evaluation module 110, and these identify for example one or more in following content of designators: the existence of HLA type, genetic marker, sex hormone level, Y chromosome test, hormonal readiness, level of growth hormone or blood group.For example, can utilize Y chromosome to test to determine this experimenter family relationship/family (for example, two male sex by it paternal and in related situation).In one embodiment, to the unique a plurality of designators of identity of body or one group of individuality one by one, can be used to confirm or remember an experimenter or one group of experimenter's identity, to guarantee that test result is associated uniquely with the concrete individuality of these samples is provided.In one embodiment, personal information can be supplied by this experimenter or a third party.In one embodiment, personal information can be supplied and then via evaluation module 110, be provided by this experimenter or a third party.Evaluation module 110 can utilize test strips, effluent test strips, Colorimetric test paper bar, through skin proving installation or lancet, determine personal information.For example, can utilize lancet to collect blood sample from body one by one, this blood sample can be analyzed to determine about this individual personal information, for example this individual proof of identification or consensus data.Through skin proving installation or lancet, can comprise micropin, micro-lancet, minute protrusions or microprojection.In one embodiment, the concrete DNA information obtaining from the blood sample gathering from experimenter is compared with the information being stored in database 166, and this database comprises the identification DNA information about this experimenter.In one embodiment, evaluation module 110 can may be operably coupled to one or more databases or look-up table, and these one or more databases or look-up table for example can comprise and body or one group of identification hereditary information that individuality is associated one by one.These one or more databases can be associated with evaluation module 110, or can be in evaluation module 110 outsides.These one or more databases can be privately owned or disclose available database.
In one embodiment, system 100 utilization is configured for this first result of causing or supporting this assessment to the software of the transmission of entity 160 outside the venue.For example, this software can be configured for and at least one, carry out below: internet, personal communicator, personal computer, laptop computer, palmtop computer, PDA(Personal Digital Assistant), mobile phone or image capture apparatus.This software can be equipped with an evaluation module 110 or separate with evaluation module 110.Can via in website, retail shop one or more, via downloading this software or via providing this software by this software of mail reception.Extraly, can be by one or more this softwares that provide in government entity or healthy clinic.
Transport module 130 may be operably coupled to evaluation module 110.In one embodiment, transport module 130 may be operably coupled to electronic memory 120.Transport module 130 is configured for from electronic memory 120 and obtains the information being associated with this first result, and this first result of this assessment is transferred to an entity 160 outside the venue.In one embodiment, transport module 130 and a Network Interface Module 168 couple for transport module 130 being connected to entity 160 outside the venue.Further, this Network Interface Module can couple for this transport module of sensing and this network activity being connected between entity outside the venue with a sensor.In one embodiment, transport module 130 and scheduler module 170 for example clock or timer couple, for the transmission of this first result of this assessment is dispatched.This type of transmission can occur at any time, comprise the time that and then this first result is offered to electronic memory 120, then this first result is offered to time of network activity of the minimizing of electronic memory 120, or then this first result is offered to the time of having dispatched of electronic memory 120.In one embodiment, transport module 130 comprise for from electronic memory 120, receive the information being associated with this first result circuit and for by the communication being associated with this first result to a circuit for entity 160 outside the venue.
In one embodiment, a system comprises a common receiver module 162 by entity 160 uses outside the venue.Receiver module 162 may be embodied as network interface etc., for receive this first result of this assessment from transport module 130.In one embodiment, receiver module 162 can may be operably coupled to one or more databases or look-up table, and these one or more databases or look-up table can comprise the information being for example associated with morbid state or situation.In one embodiment, this receiver module couples with the database 164 by entity 160 operations outside the venue.These one or more databases can be associated with receiver module 162, or can be in entity 160 outsides outside the venue.These one or more databases can be privately owned or disclose available database.In one embodiment, receiver module 162 comprises for receive the circuit of information and the circuit of inquiring about these one or more databases or look-up table for the information based on receiving from transport module 130 from transport module 130.In one embodiment, follow and the inquiry based on these one or more databases or look-up table, receiver module 162 can be determined a diagnosis or treatment or the result of this data base querying is offered to entity 160 outside the venue.In one embodiment, receiver module 162 comprises that electronic memory stores the first result of this assessment, and if desired, the identifier that personal information or evaluation module are unique.
In one embodiment, second result of entity 160 definite these assessments outside the venue.Whether this of this assessment the second result can comprise at least in part based on existing one of at least one pathogen to diagnose or therapeutic scheme in this sample.This of this assessment the second result can be the first result of this assessment, or this second result of this assessment can be that a kind of of this first result alternately represents.For example, if this first result comprises in this sample, have pathogenicity antigen, this second result can comprise this pathogenicity antigen of existence or a kind of alternately expression so, for example, have the indication of pathogen.In one embodiment, entity 160 is given this experimenter by this second readout of this assessment outside the venue.This type of reception and registration can be via receiver module 162 or by for example via phone or Email and directly convey to this experimenter.In one embodiment, receiver module 162 comprises and is configured for the circuit that this second result of this assessment is transferred to a reporting modules 140.In one embodiment, reporting modules 140 is determined this second result of this assessment, and this second result can comprise a diagnosis as described earlier or therapeutic scheme.For example, reporting modules 140 can may be operably coupled to one or more databases or look-up table, and these one or more databases or look-up table can comprise the information being for example associated with morbid state or situation.Reporting modules 140 can be given this experimenter by second report the test of this assessment.Reporting modules 140 can be oriented to contiguous this experimenter (for example, away from outside the venue entity 160).
After this first result of this assessment being ranked for transmission, reporting modules 140 can be given this experimenter by this second result/diagnosis report of this assessment.Before this first result of this assessment being ranked for transmission, reporting modules 140 can be given this experimenter by this second result/diagnosis report of this assessment.In one embodiment, reporting modules 140 can be some these the second result/diagnosis of the subjects reported being associated.For example, one family unit can utilize one or more evaluation modules 110 to assess one group of kinsfolk or whole home unit.Reporting modules 140 can be reported for whole home unit one or more diagnostic results (for example,, for the report of one family unit exists pathogen or have pathogen for other kinsfolk reports) of assessment.Reporting modules 140 can comprise that display circuit or other circuit convey to this experimenter by information.
Benefit module 150 is operationally coupled to one or more in evaluation module 110, reporting modules 140 or transport module 130.Benefit module 150 comprises for receive the circuit of information from evaluation module 110, reporting modules 140 or receiver module 162.This benefit module receives with this first result of this assessment or any or two information that are associated in this second result and comprises the definite suitable benefit to this experimenter of the information of circuit based on its reception.For example, benefit module 150 can be notified this experimenter by a benefit via one or more startup the in following content: postal delivery, Email, alphanumeric code, printable file, notify, make a phone call or contact face-to-face.In one embodiment, this experimenter can receive a benefit notice via one or more in wired connection, wireless signal, digital signal, radio-frequency (RF) identification (RFID) label signal, communication network or wireless identification tag signal.Can after this first result of this assessment being ranked for transmission, receive this benefit notice.Can before this first result of this assessment being ranked for transmission, receive this benefit notice.Can be directly or indirectly from this outside the venue entity receive this benefit notice.For example, this benefit can be posted on a website or database, then this experimenter can access the notice that this website or database are retrieved this benefit or this benefit.In one embodiment, this benefit can be at least in part based in following content at least one and determine: this of this assessment the first result, the position of this assessment, the time of this assessment, transmission time of this first result of this assessment maybe.This benefit can be at least in part by this entity and determining outside the venue.In one embodiment, this system comprises a location sensing modules 172, and for example GPS (GPS) receiver, carries out the position of this assessment or the current location of this location sensing modules for determining.In one embodiment, this system comprises a scheduler module 170, and for example timer or clock, for determining the time of this assessment or the time of transmitting this first result.In one embodiment, this benefit can be definite according to probability at least in part.For example, can have 10% chance receive a kind of larger/more conform with hope/more valuable benefit and 90% chance receive a kind of less/more do not conform with hope/be worth lower benefit.Extraly, this benefit can comprise for the one or more benefit in this experimenter or a people except this experimenter.In one embodiment, position that can be based on this assessment and determine a benefit, to locate this experimenter's geographic area.Alternately, a kind of benefit that more conforms with hope can be offered to a geographic position behind location and for example be subject to the body one by one in a region that a kind of epidemic disease affects.In addition,, in order to encourage fast sampling and assessment, at body one by one, in certain time frame, during for example at a kind of epiphytotics burst period use device 100, can provide a kind of benefit that more conforms with hope.
This benefit can comprise a kind of financial benefit.For example, this finance benefit can comprise one or more in money benefit, returning, discount or reward voucher.Money benefit can be to encourage a kind of mode that conforms with hope of body one by one; Yet, it should be noted that except financial benefit, other benefits can be provided; Alternately, a benefit can comprise a financial ingredient, in conjunction with a non-financial ingredient.In one embodiment, this finance benefit can have the cost that is less than this sample of assessment a value, be substantially equal to assess this sample cost a value or be greater than a value of the cost of assessing this sample.In one embodiment, the value of this finance benefit can equal the cost of acquisition device 100, to offset the cost of buying this device.Alternately, the value of this benefit can be greater than the cost of buying this device, to further encourage individuality to carry out use device 100.
This benefit can be associated with a kind of therapeutic benefit is provided for this experimenter.For example, this therapeutic benefit can comprise one or more in following content: for this experimenter's treatment, for the qualification of this experimenter's treatment or for the priority status of this experimenter's treatment.For example, when the assessment result indication of this sample exists the pathogen with specific curable substance, a benefit can comprise the qualified notice of accepting this medicine of this experimenter, and this experimenter then may send or obtain this notice.Alternately, when the assessment result indication of this sample exists with drug injection for example in public places during the medicable pathogen of available injection, a kind of benefit can comprise the priority status that receives this injection.
This benefit can also be associated with a kind of preventative benefit is provided.For example, this preventative benefit can comprise one or more in the qualification of vaccine, vaccine or the priority status of vaccine.For example, whether if exist a kind of specific pathogen to indicate this experimenter may tend to infect a kind of specific disease, this benefit can comprise a kind of vaccine inoculation so.Alternately, if the pathogen that this experimenter's assessment indication is associated with a kind of specified disease, this experimenter's relatives (for example,, by the someone relevant to this experimenter of family) can receive a kind of benefit comprising for the vaccine of indicated disease so.In addition, this preventative benefit can comprise a quarantine scheme.In one embodiment, this preventative benefit can comprise health officer's notice.For example, health officer can be notified and commander to this experimenter's dwelling to start potentially a quarantine scheme.
This benefit can be associated with a kind of diagnosis benefit.For example, this diagnosis benefit can comprise a test suggestion.In some instances, the pathogen of the particular type based on detected may need further test, for example, to determine more accurately whether this experimenter has a kind of specific disease or illness.In one embodiment, this diagnosis benefit can comprise a kind of for assessment of second sample to determine the means that whether have at least one pathogen in this second sample.For example,, if a kind of potential illness of a kind of pathogen indication can the pathogen based on indicated provide a further test to this experimenter so.In one embodiment, benefit module 150 can be passed on a kind of extra benefit in the situation that user starts a kind of therapeutic benefit/treatment or a kind of preventative benefit.
Fig. 2 illustrates an operating process 200 of showing a plurality of exemplary operations." beginning " or " end " that should be understood that the appointment in operational flowchart explained the mode with a kind of restriction not at this.This type of appointment is not deterministic but is provided to as a reference point.Illustrated in and described process or method can comprise other processes or method, these other processes or method comprise other steps or feature.At this, be not intended to pass on and cannot carry out other operations before or after graphic middle described operation.In Fig. 2 and in subsequently graphic of different examples that comprises operating process, can provide and discuss and explain with respect to the above-described example of Fig. 1 and/or with respect to other examples and context.However, it should be understood that and can in the revision in many other environment and context and/or at Fig. 1, carry out these operating processes.Equally, although different operating processes shows as illustrated one or more orders, should be understood that different operations can carry out by order except illustrated those order, or can side by side carry out.
After one starts operation, operating process 200 moves to operation 210.Operation 210 has been described from a health care facility gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess this biological specimen.
Then, operating 220 has described this assessment first result to carry out electric queuing and for being transferred to an entity outside the venue.
Then, operating 230 has described after this first result of this assessment being ranked for transmission second report the test of this assessment to this experimenter.
Fig. 3 illustrates a plurality of alternate embodiments of the example operational flow 200 of Fig. 2.Fig. 3 illustrates a plurality of example embodiment, wherein operates 210 and can comprise at least one operation bidirectional.Operation bidirectional can comprise operation 302.
Operation 302 illustrates for whether there is at least one antigen in this biological specimen to be assessed this sample, and this antigen shows in this biological specimen, whether there is this at least one pathogen.
Fig. 4 illustrates a plurality of alternate embodiments of the example operational flow 200 of Fig. 2.Fig. 4 illustrates a plurality of example embodiment, wherein operates 210 and can comprise at least one operation bidirectional.Operation bidirectional can comprise operation 402 and/or operate 404.
Whether operation 402 illustrates for existing has immunoreactive at least one antibody with this at least one pathogen and this sample is assessed.Further, operating 404 illustrates and utilizes chip lab, mensuration, effluent test strips, Colorimetric test paper bar, effluent Colorimetric test paper bar, at least one in skin proving installation or lancet to determine whether to exist with this at least one pathogen to have immunoreactive this at least one antibody.
Fig. 5 illustrates an operating process 500 of showing a plurality of exemplary operations.Fig. 5 illustrates an example embodiment, and wherein the example operational flow 200 of Fig. 2 can comprise at least one operation bidirectional.Operation bidirectional can comprise operation 510.
Starting operation, operate 210, operating 220 and operate after 230, operating process 500 moves to operation 510.Operation 510 illustrates storage and the information that whether exists at least one pathogen to be associated in this biological specimen in an electronic memory.
Fig. 6 illustrates an operating process 600 of showing a plurality of exemplary operations.Fig. 6 illustrates an example embodiment, and wherein the example operational flow 200 of Fig. 2 can comprise at least one operation bidirectional.Operation bidirectional can comprise operation 610.
Starting operation, operate 210, operating 220 and operate after 230, operating process 600 moves to operation 610.Operation 610 illustrates and utilizes at least one the Fuzzy Processing comprise in coded format, alphanumeric code, image or password form whether to have at least one pathogen to this subjects reported.
Fig. 7 illustrates an operating process 700 of showing a plurality of exemplary operations.Fig. 7 illustrates an example embodiment, and wherein the example operational flow 200 of Fig. 2 can comprise at least one operation bidirectional.Operation bidirectional can comprise operation 710.
Starting operation, operate 210, operating 220 and operate after 230, operating process 700 moves to operation 710.Operation 710 illustrates this first result of this assessment is automatically transferred to entity outside the venue.
Fig. 8 illustrates an operating process 800 of showing a plurality of exemplary operations.Fig. 8 illustrates an example embodiment, and wherein the example operational flow 200 of Fig. 2 can comprise at least one operation bidirectional.Operation bidirectional can comprise operation 810 and/or operate 812.
Starting operation, operate 210, operating 220 and operate after 230, operating process 800 moves to operation 810.Operation 810 illustrates this first result of this assessment is transferred to entity outside the venue.
Operation 812 illustrates at least one that utilize in wired connection, wireless signal, digital signal, radio-frequency (RF) identification (RFID) label signal, communication network or wireless identification tag signal this first result of this assessment is transferred to this entity outside the venue.
Fig. 9 illustrates an operating process 900 of showing a plurality of exemplary operations.Fig. 9 illustrates an example embodiment, and wherein the example operational flow 200 of Fig. 2 can comprise at least one operation bidirectional.Operation bidirectional can comprise operation 910.
Starting operation, operate 210, operating 220 and operate after 230, operating process 900 moves to operation 910.Operation 910 illustrates to utilize to be configured for and supports this first result of this assessment to transfer to this software of entity outside the venue.
Figure 10 illustrates an operating process 1000 of showing a plurality of exemplary operations.Figure 10 illustrates an example embodiment, and wherein the example operational flow 200 of Fig. 2 can comprise at least one operation bidirectional.Operation bidirectional can comprise operation 1010 and/or operate 1012.
Starting operation, operate 210, operating 220 and operate after 230, operating process 1000 moves to operation 1010.Operation 1010 illustrates as this experimenter passes on a benefit and notifies.
Operation 1012 illustrate via following at least one pass on this benefit notice for this experimenter: postal delivery, Email, alphanumeric code, printable file, notify, make a phone call or contact face-to-face.
Figure 11 illustrates a plurality of alternate embodiments of the example operational flow 800 of Fig. 8.Figure 11 illustrates a plurality of example embodiment, and wherein the example operational flow 800 of Fig. 8 can comprise at least one operation bidirectional.Operation bidirectional can comprise operation 1110.
Operation 1110 illustrates to be notified a benefit to convey to this experimenter after entity outside the venue this first result of this assessment being transferred to this.
Figure 12 illustrates a partial view of an exemplary computer program product 1200, and this exemplary computer program product comprises that a computer program 1204 for carrying out a computer processes on a calculation element.Embodiment of exemplary computer program product 1200 use one can record type signal bearing medium 1202 provide, and can comprise: be configured for remotely from a health care facility and cause gathering from an experimenter's a biological specimen for the computer usable code that whether has the automatic evaluation of at least one pathogen; Be configured for this assessment first result is carried out to electric queuing and for being transferred to a computer usable code for entity outside the venue; And be configured for this first result of this assessment is ranked for after transmitting by second report the test of this assessment the computer usable code to this experimenter.This computer usable code can be the instruction that for example computing machine is executable and/or logic is implemented.In an implementation, signal bearing medium 1202 can comprise computer-readable medium 1206.In an implementation, signal bearing medium 1202 can comprise recordable medium 1208.In an implementation, signal bearing medium 1202 can comprise communication media 1210.It should be noted that this second result can be via display or via the communication of audio frequency, visual or other tactile feedback types and convey to this experimenter.
Aforementioned detailed description is by the various embodiment that use block diagram, process flow diagram and/or example to state equipment and/or process.So far, this type of block diagram, process flow diagram and/or example comprise one or more functions and/or operation, each function in this type of block diagram, process flow diagram or example and/or operation can by large-scale hardware, software, firmware or almost its any combination come independently and/or jointly implement.In one embodiment, some parts of theme described here can be implemented via special IC (ASIC), field programmable gate array (FPGA), digital signal processor (DSP) or other integrated forms.Yet, a whole or part for some aspects of embodiment disclosed here (for example can be embodied as one or more computer programs of moving on one or more computing machines comparably in integrated circuit, one or more programs of moving in one or more computer systems), one or more programs of moving on one or more processors (for example, one or more programs of moving on one or more microprocessors), firmware, or above every almost any combination, and according to this disclosure, design circuit and/or the code of writing for software and/or firmware will be that those skilled in the art understands completely.In addition, the mechanism of theme described here can be distributed as program product in a variety of forms, and regardless of the particular type that is used in fact carrying out the signal bearing medium of this distribution, the illustrative embodiment of theme described here is all suitable for.The example of non-instantaneous signal bearing medium includes but not limited to as follows: a medium that can record type, such as floppy disk, hard disk drive, compact disk (CD), digital video disc (DVD), numerical tape, computer memory etc.; With the medium of transport-type, for example numeral and/or analogue communication medium (for example, fiber optic cables, waveguide, wire communication link, wireless communication link (for example, transmitter, receiver, transmission logic, receive logic etc.) etc.).
In broad sense, described herein can by large-scale hardware, software, firmware and/or its any combination comes independently and/or the different aspect jointly implemented can be regarded as by dissimilar " circuit " and forms.Therefore, " circuit " includes but not limited to as used in this: the circuit with at least one discrete circuit, the circuit with at least one integrated circuit, the circuit with at least one special IC, the circuit of the universal computing device that formation is configured by computer program is (for example,, by the multi-purpose computer of carrying out at least in part the computer program configuration of process described herein and/or device; Or by the microprocessor of carrying out at least in part the computer program configuration of process described herein and/or device), (for example form the circuit of storage arrangement, storer (for example, random access, flash memory, read-only etc.) a plurality of forms), and/or the circuit (for example, modulator-demodular unit, communication switchboard, optoelectronic device etc.) of formation communicator.Theme described herein can be implemented with the form of analog or digital or certain combination of the two.
Device described herein and/or process can be incorporated in a data handling system.Data handling system generally includes one or more in the following: system unit housing, video display devices, storer such as volatibility or nonvolatile memory, processor such as microprocessor or digital signal processor, computational entity such as operating system, driver, graphic user interface and application program, one or more interactive device (such as touch pad, touch-screen, antenna etc.), and/or the control system that comprises feedback control loop and control motor is (for example,, for the feedback of sense position and/or speed; Be used for moving and/or adjusting the control motor of assembly and/or quantity).A data handling system can utilize suitable commercially available assembly to implement, for example those assemblies seen in common calculate in data/communication and/or network calculations/communication system.
Assembly described herein (for example operation), device, object and follow their discussion to be used as the example for clear concept, and can expect different configuration modifications.Therefore, as used herein, the concrete example of stating and appended discussion are intended to represent their more universal class.In general, the use of any specific example is intended to represent its classification, and should for example, as the restriction of the specific components for not comprising (operation), device and object.
About any plural number and/or singular references substantially as used herein, reader should be based on context and/or plural number need to being translated into odd number and/or odd number is translated into plural number of application.For clarity, the conversion of different singular/plural is in this not clearly statement.
Theme described herein illustrates sometimes is the different assemblies that comprise in different other assemblies or the different assemblies that connect from different other assemblies.Should be understood that the framework of describing is like this only exemplary, and in fact a lot of other frameworks also can be implemented to reach identical functional.In conceptual meaning, the arrangement that can realize arbitrarily the assembly of same functionality " is associated " all effectively, makes so desirable functional being achieved.Therefore, any two assemblies that are combined to realize particular functionality at this can be regarded as " being associated with each other ", make so desirable functional being achieved, and irrelevant with framework or intermediate module.Equally, any two assemblies that are so associated also can be regarded as each other " being operably connected ", or " operationally coupling ", desirable functional to reach, and any two assemblies that can so be associated also can be regarded as each other " operationally can couple ", desirable functional to reach.The concrete example that operationally can couple includes but not limited to can coordinate physically and/or mutual physically assembly, and/or can be wirelessly mutual assembly alternately and/or wirelessly, and/or mutual and/or assembly that can be logically mutual logically.
In some cases, one or more assemblies this can be called as " being configured to, " " by ... configuration, " " can be configured to, " " thereby can operate/operability, " " adaptive/can be adaptive, " " can ", " can meet/be coincident with " etc.Active state assembly and/or passive state assembly and/or holding state assembly can be contained conventionally in this type of term (for example " being configured for "), unless the context requires otherwise.
Although illustrated and described the particular aspects at this theme of the present invention, but can make a change and revise in the situation that not departing from theme described here and broad aspect thereof, and therefore, appended claims will belong to the true spirit of theme described here and all these type of changes and the modification in scope in its encompasses.Substantially, at this and especially at appended claims (for example, the main body of appended claims) term using in as open to the outside world term (is for example intended to substantially, term " comprise " should be understood to " including but not limited to; " term " have " should be understood to " at least having; " term " comprises " should be understood to " including but not limited to, " etc.).If intention shows a given number of introduced claim statement, will in this claim, state clearly so this intention, and in the situation that not there is not this statement, not have this intention.For example, in order to help to understand, following appended claims may comprise use introductory phrase " at least one " and " one or more " introduce claim statement.Yet, the use of this type of phrase should not explainfor hint is introduced claim statement by indefinite article " " or " a kind of ", the any concrete claim of the claim statement that comprises such introduction is restricted to the claim that only comprises such statement, even in identical claim, comprise that guiding phrase " one or more " or " at least one " and indefinite article are for example for example, during " one " or " a kind of " (, " one " and/or " a kind of " should typically be interpreted as meaning " at least one " or " one or more "); This is effective in equally for introducing the use of the definite article of claim statement.In addition, even if state clearly the given number of a claim statement of introducing, one of ordinary skill in the art will recognize that number that this statement also typically should be interpreted as meaning at least this statement (for example, do not have other modifiers " two statements " without modifying statement, typically mean at least two statements, or two or more statements).In addition, in use, be similar in those examples of convention of " in A, B and C at least one etc. ", in general, this structure be intended to regard to those skilled in the art should be by understanding with regard to the meaning of this convention (for example, " there is A, B and the system of at least one in C " by including but not limited to there is separately A, there is separately B, have separately C, A together with B, A together with C, B together with C and/or A, the B system together with C three etc.).In use, be similar in those examples of convention of " in A, B or C at least one etc. ", in general, this structure be intended to regard to it should be appreciated by those skilled in the art that the meaning of this convention (for example, " there is the system of at least one in A, B or C " by including but not limited to there is separately A, there is separately B, have separately C, A together with B, A together with C, B together with C and/or A, the B system together with C three etc.).Typically, no matter be in instructions, claims or accompanying drawing, present the separation property word of two or more alternative terms and/or phrase and all should be understood to consider any or the possibility of these two terms in of comprising in these terms, these terms, unless context is stipulated in addition.For example, phrase " A or B " will be typically interpreted as the possibility that comprises " A " or " B " or " A and B ".
With respect to appended claims, those skilled in the art will appreciate that wherein the operation of statement can be carried out with any order conventionally.Equally, although different operating processes shows as one or more orders, should be understood that the order of different operations can be carried out by the order except illustrated those order, or can side by side carry out.That the example of this type of oscillation sorting can comprise is overlapping, intersection, interruption, rearrangement, increment, preparation, supplement, simultaneously, the sequence of reverse or other variations, unless context is stipulated in addition.In addition, term picture " in response to, " " with ... relevant, " or other past tense adjectives be not conventionally intended to get rid of this type of and change, unless context is stipulated in addition.
Although disclosed different aspect and embodiment at this, other aspects and embodiment will be obvious to those skilled in the art.Different aspect disclosed here and embodiment are for illustrative purposes, and are not intended to limit, and wherein real scope and spirit are indicated by following claims.

Claims (65)

1. a system, comprising:
An evaluation module, this evaluation module for from a health care facility to gathering a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess at this biological specimen;
An electronic memory, this electronic memory is for ranking and for being transferred to an entity outside the venue to this assessment first result; And
A reporting modules, this report module for this first result of this assessment is ranked for transmission after by second report the test of this assessment to this experimenter.
2. the system as claimed in claim 1, wherein from a health care facility to gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess and comprise this biological specimen:
Whether for existing at least one antigen or nucleic acid to assess this sample in this biological specimen, this antigen or nucleic acid show in this biological specimen, whether there is this at least one pathogen.
3. the system as claimed in claim 1, wherein from a health care facility to gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess and comprise this biological specimen:
For whether existing with this at least one pathogen, there is immunoreactive at least one antibody to assess this sample.
4. whether system as claimed in claim 3, wherein have immunoreactive at least one antibody that this sample is assessed and comprised for existing with this at least one pathogen:
Utilize chip lab, proving installation, effluent test strips, Colorimetric test paper bar, effluent Colorimetric test paper bar, at least one in skin proving installation or lancet to determine whether to exist with this at least one pathogen and have immunoreactive this at least one antibody.
5. system as claimed in claim 4, wherein this chip lab, this test, this effluent test strips, this Colorimetric test paper bar, this effluent Colorimetric test paper bar, this in skin proving installation or this lancet this at least one comprise a unique identifier.
6. system as claimed in claim 5, wherein this unique identifier comprises at least one in bar code, RFID label or wireless identification tag.
7. the system as claimed in claim 1, wherein this at least one pathogen comprises at least one in virus, parasitic animal and plant, bacterium, fungi, toxin or toxigenic pathogen.
8. the system as claimed in claim 1, wherein this at least one pathogen comprises at least one in influenza A virus, subtypes of influenza A virus, influenza B virus or influenza virus C.
9. the system as claimed in claim 1, further comprises:
An electronic memory, this electronic memory is for storing and the information that whether exists this at least one pathogen to be associated at this biological specimen.
10. the system as claimed in claim 1, further comprises:
A transport module, this transport module is for being transferred to this entity outside the venue by this first result of this assessment.
11. the system as claimed in claim 1, further comprise:
A benefit module, this benefit module is for passing on the notice for a kind of benefit of this experimenter.
12. systems as claimed in claim 11, wherein this benefit comprises a kind of financial benefit.
13. systems as claimed in claim 12, wherein this financial benefit comprises at least one in money benefit, returning, discount or coupon.
14. systems as claimed in claim 11, wherein this benefit is associated with a kind of preventative benefit is provided.
15. 1 kinds of systems, comprising:
An evaluation module, this evaluation module for from a health care facility to gathering a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess at this biological specimen;
An electronic memory, this electronic memory is for ranking and for being transferred to an entity outside the venue to this assessment first result; And
A benefit module, this benefit module is used for this first result of this assessment is ranked for receiving the notice for a kind of benefit of this experimenter after transmitting.
16. systems as claimed in claim 15, wherein from a health care facility to gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess and comprise this biological specimen:
Whether for existing at least one antigen or nucleic acid to assess this sample in this biological specimen, this antigen or nucleic acid show in this biological specimen, whether there is this at least one pathogen.
17. systems as claimed in claim 15, wherein from a health care facility to gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess and comprise this biological specimen:
For whether existing with this at least one pathogen, there is immunoreactive at least one antibody to assess this sample.
Whether 18. systems as claimed in claim 17, wherein have immunoreactive at least one antibody that this sample is commented and comprised for existing with this at least one pathogen:
Utilize chip lab, proving installation, effluent test strips, Colorimetric test paper bar, effluent Colorimetric test paper bar, at least one in skin proving installation or lancet to determine whether to exist with this at least one pathogen and have immunoreactive this at least one antibody.
19. systems as claimed in claim 18, wherein this chip lab, this test, this effluent test strips, this Colorimetric test paper bar, this effluent Colorimetric test paper bar, this in skin proving installation or this lancet this at least one comprise a unique identifier.
20. systems as claimed in claim 19, wherein this unique identifier comprises at least one in bar code, RFID label or wireless identification tag.
21. systems as claimed in claim 15, wherein this at least one pathogen comprises at least one in virus, parasitic animal and plant, bacterium, fungi, toxin or toxigenic pathogen.
22. systems as claimed in claim 15, wherein this at least one pathogen comprises at least one in influenza A virus, subtypes of influenza A virus, influenza B virus or influenza virus C.
23. systems as claimed in claim 15, further comprise:
An electronic memory, this electronic memory is for storing and the information that whether exists this at least one pathogen to be associated at this biological specimen.
24. systems as claimed in claim 15, further comprise:
A transport module, this transport module is for being transferred to this entity outside the venue by this first result of this assessment.
25. systems as claimed in claim 15, the notice wherein receiving for a kind of benefit of this experimenter comprises:
By at least one in wired connection, wireless signal, digital signal, radio-frequency (RF) identification (RFID) label signal, communication network or wireless identification tag signal, receive the notice for this benefit of this experimenter.
26. systems as claimed in claim 15, wherein this benefit module is configured for the notice of passing on for a kind of benefit of this experimenter.
27. systems as claimed in claim 26, wherein this benefit comprises a kind of financial benefit.
28. 1 kinds of devices, comprising:
An evaluation module, this evaluation module for from a health care facility to gathering a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess at this biological specimen;
The electronic memory being connected with this evaluation module, this electronic memory is for ranking and for being transferred to an entity outside the venue to this assessment first result; And
The benefit module being connected with this evaluation module, this benefit module is used for this first result of this assessment is ranked for receiving the notice for a kind of benefit of this experimenter after transmitting.
29. 1 kinds of computer programs, comprising:
Can be record type, non-transient, the medium of carrying signal, this medium is carrying
Computer usable code, this computer usable code is configured for and causes from a health care facility gather a biological specimen from an experimenter for whether existing at least one pathogen remotely to carry out automatic evaluation one time this biological specimen;
Computer usable code, this computer usable code is configured for carries out electric queuing and for being transferred to an entity outside the venue to this assessment first result; And
Computer usable code, this computer usable code be configured for this first result of this assessment is ranked for after transmitting by second report the test of this assessment to this experimenter.
30. computer programs as claimed in claim 29, further comprise:
Computer usable code, whether this computer usable code there is the relevant information of at least one pathogen in being configured for and preserving this biological specimen in an electronic memory.
31. computer programs as claimed in claim 29, further comprise:
Computer usable code, this computer usable code is configured for to be utilized at least one that comprise in coded format, alphanumeric code, image or password form to obscure to report in this experimenter, whether to have at least one pathogen.
32. computer programs as claimed in claim 29, further comprise:
Computer usable code, this computer usable code is configured for the first result of this assessment is transferred to this entity outside the venue.
33. computer programs as claimed in claim 32, are wherein transferred to this entity outside the venue by the first result of this assessment, comprising:
This first result is transferred to the outer entity of an intermediate field, supplies this entities access outside the venue.
34. computer programs as claimed in claim 32, further comprise:
Computer usable code, this computer usable code is configured for and in this assessment result, is transferred to this and benefit notice is conveyed to this experimenter after entity outside the venue.
35. computer programs as claimed in claim 29, further comprise:
Computer usable code, this computer usable code is configured for a benefit notice is conveyed to this experimenter.
36. 1 kinds of computer programs, comprising:
Can be record type, non-transient, the medium of carrying signal, this medium is carrying
Computer usable code, this computer usable code is configured for and causes from a health care facility gather a biological specimen from an experimenter for whether existing at least one pathogen remotely to carry out automatic evaluation one time this biological specimen;
Computer usable code, this computer usable code is configured for carries out electric queuing and for being transferred to an entity outside the venue to this assessment first result; And
Computer usable code, this computer usable code is configured for this first result of this assessment is ranked for receiving the notice for a kind of benefit of this experimenter after transmitting.
37. computer programs as claimed in claim 36, further comprise:
Computer usable code, whether this computer usable code there is the relevant information of at least one pathogen in being configured for and preserving this biological specimen in an electronic memory.
38. computer programs as claimed in claim 36, further comprise:
Computer usable code, this computer usable code is configured for to be utilized at least one that comprise in coded format, alphanumeric code, image or password form to obscure to report in experimenter, whether to have at least one pathogen.
39. computer programs as claimed in claim 36, further comprise:
Computer usable code, this computer usable code is configured for the first result of this assessment is transferred to this entity outside the venue.
40. computer programs as claimed in claim 39, are wherein transferred to this entity outside the venue by the first result of this assessment, comprising:
This first result is transferred to the outer entity of an intermediate field, supplies this entities access outside the venue.
41. computer programs as claimed in claim 39, further comprise:
Computer usable code, this computer usable code is configured for and in this assessment result, is transferred to this and benefit notice is conveyed to this experimenter after entity outside the venue.
42. computer programs as claimed in claim 36, the notice wherein receiving for a kind of benefit of this experimenter comprises:
By at least one in wired connection, wireless signal, digital signal, radio-frequency (RF) identification (RFID) label signal, communication network or wireless identification tag signal, receive the notice for this benefit of this experimenter.
43. 1 kinds of methods, comprising:
From a health care facility to gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess this biological specimen;
The first result of this assessment is carried out to electric queuing, to be transferred to an entity outside the venue; And
After the first result of this assessment being ranked and transmit, by the second report the test of this assessment, give this experimenter.
44. methods as claimed in claim 43, wherein from a health care facility to gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess and comprise this biological specimen:
Whether for existing at least one antigen or nucleic acid to assess this sample in this biological specimen, this antigen or nucleic acid show in this biological specimen, whether there is this at least one pathogen.
45. methods as claimed in claim 43, wherein from a health care facility to gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess and comprise this biological specimen:
For whether existing with this at least one pathogen, there is immunoreactive at least one antibody to assess this sample.
Whether 46. methods as claimed in claim 45, wherein have immunoreactive at least one antibody that this sample is commented and comprised for existing with this at least one pathogen:
Utilize chip lab, proving installation, effluent test strips, Colorimetric test paper bar, effluent Colorimetric test paper bar, at least one in skin proving installation or lancet to determine whether to exist with this at least one pathogen and have immunoreactive this at least one antibody.
47. methods as claimed in claim 46, wherein this chip lab, this test, this effluent test strips, this Colorimetric test paper bar, this effluent Colorimetric test paper bar, this in skin proving installation or this lancet this at least one comprise a unique identifier.
48. methods as claimed in claim 47, wherein unique identification comprises at least one in bar code, RFID label or wireless identification tag.
49. methods as claimed in claim 43, wherein this at least one pathogen comprises at least one in virus, parasitic animal and plant, bacterium, fungi, toxin or toxigenic pathogen.
50. methods as claimed in claim 43, further comprise:
Storage and the information that whether exists at least one pathogen to be associated in this biological specimen in an electronic memory.
51. methods as claimed in claim 43, further comprise:
The first result of this assessment is transferred to this entity outside the venue.
52. methods as claimed in claim 43, further comprise:
For this experimenter passes on a benefit notice.
53. methods as claimed in claim 52, wherein this benefit comprises a kind of financial benefit.
54. methods as claimed in claim 53, wherein this finance benefit comprises at least one in money benefit, returning, discount or coupon.
55. methods as claimed in claim 52, wherein this benefit to provide a kind of preventative benefit relevant.
56. 1 kinds of methods, comprising:
From a health care facility to gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess this biological specimen;
The first result of this assessment is carried out to electric queuing, to be transferred to an entity outside the venue; And
After the first result of this assessment being ranked and transmit, by the second report the test of this assessment, give this experimenter.
57. methods as claimed in claim 56, wherein from a health care facility to gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess and comprise this biological specimen:
Whether for existing at least one antigen or nucleic acid to assess this sample in this biological specimen, this antigen or nucleic acid show in this biological specimen, whether there is this at least one pathogen.
58. methods as claimed in claim 56, wherein from a health care facility to gather a biological specimen from an experimenter for whether existing at least one pathogen remotely automatically to assess and comprise this biological specimen:
For whether existing with this at least one pathogen, there is immunoreactive at least one antibody to assess this sample.
Whether 59. methods as claimed in claim 58, wherein have immunoreactive at least one antibody that this sample is commented and comprised for existing with this at least one pathogen:
Utilize chip lab, proving installation, effluent test strips, Colorimetric test paper bar, effluent Colorimetric test paper bar, at least one in skin proving installation or lancet to determine whether to exist with this at least one pathogen and have immunoreactive this at least one antibody.
60. methods as claimed in claim 56, wherein this at least one pathogen comprises at least one in virus, parasitic animal and plant, bacterium, fungi, toxin or toxigenic pathogen.
61. systems as claimed in claim 56, wherein this at least one pathogen comprises at least one in influenza A virus, subtypes of influenza A virus, influenza B virus or influenza virus C.
62. methods as claimed in claim 56, further comprise:
Storage and the information that whether exists at least one pathogen to be associated in this biological specimen in an electronic memory.
63. methods as claimed in claim 56, further comprise:
The first result of this assessment is transferred to this entity outside the venue.
64. methods as described in claim 63, further comprise:
By second report the test of this assessment, give this experimenter, wherein entity is definite outside the venue by this for the second result of this assessment.
65. methods as described in claim 63, further comprise:
The first result of this assessment is being transferred to this outside the venue after entity, for this experimenter passes on a benefit notice.
CN201280032988.9A 2011-05-06 2012-05-03 Sample evaluation result reporting after queuing the result for transmission Pending CN103635807A (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US13/068,291 2011-05-06
US13/068,296 2011-05-06
US13/068,301 2011-05-06
US13/068,295 US20120284047A1 (en) 2011-05-06 2011-05-06 Method for receiving a notification of a benefit after queuing the result of an evaluation of a sample for transmission
US13/068,297 US20120284048A1 (en) 2011-05-06 2011-05-06 Method for reporting a result of an evaluation of a sample after queuing the result for transmission
US13/068,291 US20120284046A1 (en) 2011-05-06 2011-05-06 Computer program product for reporting a result of an evaluation of a sample after queuing the result for transmission
US13/068,298 2011-05-06
US13/068,301 US20120284049A1 (en) 2011-05-06 2011-05-06 System and device for receiving a notification of a benefit after queuing the result of an evaluation of a sample for transmission
US13/068,298 US20120284037A1 (en) 2011-05-06 2011-05-06 Computer program product for receiving a notification of a benefit after queuing the result of an evaluation of a sample for transmission
US13/068,295 2011-05-06
US13/068,297 2011-05-06
US13/068,296 US20120283138A1 (en) 2011-05-06 2011-05-06 System and device for reporting a result of an evaluation of a sample after queuing the result for transmission
PCT/US2012/036284 WO2012154488A1 (en) 2011-05-06 2012-05-03 Sample evaluation result reporting after queuing the result for transmission

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