Investigating Essential Cellular Organelles (Free Notes Included)

Osama Saeed
3 min readSep 10, 2023
Investigating Essential Cellular Organelles (Free Notes Included)

Introduction

Cells, the basic unit of life, have different sections within them all carrying out a specific task.. These sections, known as organelles, exist to ensure a cell carries out its functions correctly. Today, we will analyze the structure, contents, and functions of five important organelles. These are:

  • Mitochondria
  • Golgi apparatus
  • Cytoskeleton
  • Lysosomes
  • The nucleus.

1. Mitochondrial DNA

Mitochondria are considered to be powerhouses of the cell since they produce energy. Having said that, we will have a closer insight at their structure, contents, and the functions they carry out.

Structure

An outer and an inner membrane make up the double-membrane structure of mitochondria. Cristae formations are produced as a result of the inner membrane’s extreme folding.

A matrix is contained within the inner membrane of the mitochondria called the mitochondrial that contains the enzymes that produce energy.

The mitochondrial DNA (mtDNA), being unique to the mitochondria, contains essential proteins for cellular energy generation.

Ribosomes: The ribosomes contained in the mitochondria are smaller in size compared to the cytoplasm.

Functions

The majority of cellular respiration, which produces adenosine triphosphate (ATP), is carried out by mitochondria. ATP is the energy currency of the cell. They are required for several metabolic activities, including the citric acid cycle (Krebs cycle) and fatty acid degradation. Mitochondria are important in apoptosis (programmed cell death), cell signalling, and calcium control.

Apparatus Golgi

The Golgi apparatus, also known as the Golgi complex, is essential for protein and lipid processing and storage. The Golgi is made up by flattened membrane stacks, called cisternae. Enzymes are responsible for altering, categorizing, and packaging lipids and proteins.

Functions

Protein Modification: The Golgi modifies and sorts proteins synthesised in the endoplasmic reticulum (ER) before delivering them to their ultimate destinations. It is involved in the generation of lipids as well as the formation of lysosomes. The Golgi apparatus secretes substances by packaging them into vesicles for secretion or transit throughout the cell.

Cytoskeleton

The cytoskeleton is the cell’s structural framework that provides support, shape, and mobility. Protein Filaments: The cytoskeleton contains three types of protein filaments: microtubules, microfilaments (actin filaments), and intermediate filaments. Proteins: Tubulin (microtubules) and actin (microfilaments) are two proteins that make up these filaments.

Functions

It prevents the cell from collapsing by keeping its form. The cytoskeleton facilitates cell mobility through structures such as cilia and flagella. Intracellular Transport: It allows motor proteins to transport organelles and other cargo within the cell.

Lysosomes

Lysosomes are the recycling centers of the cell, responsible for the breakdown of waste materials.

Structure

Membrane-bound Organelles: Lysosomes are membrane-bound organelles that contain several enzymes.

Composition

Lysosomes contain hydrolytic enzymes, which can break down different compounds.

Functions

Debris Disposal: Through a process known as autophagy, they consume cellular debris, damaged organelles, and absorbed pathogens.

Lysosomes can also cause programmed cell death, often known as apoptosis, by releasing enzymes into the cell.

Nucleus

The nucleus is commonly referred to as the command centre of the cell, carrying genetic information. The nucleus, like the mitochondria, has a double-membrane structure known as the nuclear envelope. The nucleolus is a structure within the nucleus that plays a key role in ribosome production. The nucleus contains the cell’s genetic material in the form of chromatin, which condenses into chromosomes during cell division.

Functions

It controls gene expression, RNA synthesis, and protein synthesis.

Cell Division: The nucleus is vital in cell division because it ensures that genetic material is distributed correctly.

Conclusion

The cellular machinery includes the mitochondria, Golgi apparatus, cytoskeleton, lysosomes, and nucleus. Understanding their shapes and functions is essential for comprehending the intricate workings of life at the cellular level. Whether you are a first-year biology student or a seasoned researcher, these organelles are crucial to your understanding of the field.

Find hand written notes to this topic here.

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Osama Saeed
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Biochemistry Graduate from Stanford.