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Fig. IA Ratio Outputilnput rn0i 0,05 dayd post infection 10000000 W H .......... _ W _ W l 1000.000 -- -~ _'_‘_‘ : W l § § 100.000 § ; -1 -\ .. Q 0 5*; 10.000 § § g ‘ \ + + é 1.000 - — ‘ :1 w =-.-. - '2'” * ‘ T " , 1 1; MVP»-Vero MVA-HLR l 0100 -{ -- A ~ -4 A A -0.010 '1 ' ; — - l - l 5- 4 i 7 VA-BN MVA-575 L"_"'“"'““'""""'I"‘“""11‘"““'"'""""'""'"":“"'"""'"'""":““‘“"“"'“fi:‘“'““‘"T“"“”'“:”"'"""T"j”"“'""“"""""‘““’“:?::‘:j'“""“"'£‘T"“'““““'“““"""‘57“““:“""“‘“‘“""“"""‘ " | CEF BHK Vere El cv1 1435 E HeLa a HaCat Fig, 1B

W 10000 F

§ mo MVA-BM H :1 MVA-575 g 1°° MVA-HLR E 10

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CEF vero CW HeLa H368
(Cricken) (lubrkey) (Mcnkey) (Human) (H-mm)

CellsICelllines

Ovary Viral Titre: (PF U x 10 T)

Fig. 2

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Fig.4

25000 —

MVA-BN Antibody titres

20000

I MVA-BN : MVA-BN 5000 _ MVA-BN : Elstree B MVA 572 : MVA 572 MVA 572 : Elstree 10000 — _ . Elstree Wyeth 5000 —

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Weeks post vaccination

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