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1

CONVERSION KIT FOR A MACHINE FOR AUTOMATIC INTRAVASCULAR INJECTION OF SOLUTIONS

BACKGROUND

The present invention relates to a conversion kit for a machine for intravascular injection of compounds or solutions, such as parenteral solutions, e.g. X-ray contrast medium solutions, from high-pressure syringes. In particular, the present invention relates to a conversion kit which enables the use of an injection machine designed for high-pressure syringes to be use with manual syringes.

In general, injection machines for high-pressure syringes include a vessel for releasably holding a high-pressure syringe and a power-driven retractable and extendable spindle for moving the piston of the high-pressure syringe. The vessel has a receiving head provided with a cylindrical guide for tightly surrounding the distal end region of the high-pressure syringe body and having a radial recess for substantially non-rotary reception of a peripheral edge projecting from the distal end of the high-pressure syringe body. The spindle has a piston-holder releasably secured to its free end. the piston-holder having a coupling head for coupling it to the piston of the high-pressure syringe.

Injection machines are used for intravascular injection of parenteral solutions, more particularly X-ray contrast medium solutions, in phlebography, i.e. X-ray photography of leg veins for diagnosing thrombosis, and in computer tomography, in order to inject relatively large volumes, in the range of about 100 to 200 ml, in accordance with a set controlling program. In this manner, a wide variety of desired injection profiles can be obtained with a high degree of accuracy, and in a simple manner, while meeting the particular medical requirements. The various injection profiles can be stored and are therefore always available for further inspection and for future investigations.

For example, injection machines can deliver parenteral solution at rates from 0.1 to 9.9 ml/s, which can be selected in 0.1 ml/s steps, and total injected volume of about 100 to 200 ml, being injectable in portions which can be selected in 1 ml steps. Injection is carried out at relatively high pressure, in the range of several bars to several tens of bars, the pressure being electronically controlled and limited for safety reasons.

Injection machines use syringes which usually have a relatively large volume of about 100 to 200 ml. These syringes are known in clinical terminology as "high-pressure syringes" because of the relatively high pressure used for injection.

In addition to high-pressure syringes for injection machines, there is a continuing and much more extensive use in medical practice of conventional manual syringes, which usually have a relatively small volume in the range from 1 to 50 ml. In many cases it would be very desirable to use manual injection syringes in automatic injection procedures. However, manual injection syringes are generally constructed in a manner which does not fit in automatic injection machines designed for high-pressure syringes. Therefore a special machine which is designed for manual injection syringes is needed. These special machines are relatively expensive, and thus add to the overall cost of performing medical procedures.

Therefore, there remains a need in the art to provide a less complex and less expensive means and procedure for performing automatic intravascular injection of parenteral solutions from manual syringes.

2

OBJECTS OF THE INVENTION

It is one object of the present invention to provide a conversion kit which allows an automatic injection machine for high-pressure syringes to be optionally used for automatic injection using manual syringes.

SUMMARY OF THE INVENTION

The above object and others as will be apparent to one skilled in the art are accomplished according to the present 1 invention by providing a conversion kit for enabling automatic injection machines designed for high-pressure syringes to be used for intravascular injection from manual syringes. In particular, the conversion kit according to the present invention includes the following elements.

(1) At least one conversion vessel, having a receiving head with a radial recess including a first region for substantially non-rotary reception of the peripheral edge projecting from the distal end of a high-pressure syringe, and also including a second region for receiving the radial end regions of the wings of a manual injection syringe of predetermined size. The conversion vessel replaces the original vessel of the injection machine.

(2) At least one reducing sleeve for reducing the effective inner diameter of the cylindrical guide of the injector machine. The reducing sleeve includes a substantially cylindrical sleeve member, having an outer diameter which will fit snugly within the inner diameter of the cylindrical guide and having an inner diameter which will snugly receive the outer diameter of the manual syringe. The reducing sleeve also includes a peripheral edge projecting radially from the distal end of the reducing sleeve and adapted to be received in the first region of the radial recess in the receiving head, and in which the peripheral edge of the distal end of the manual syringe can be received.

(3) At least one conversion piston holder, having a radial maximum diameter equal to or less than the diameter of the piston of the manual syringe. The conversion piston holder is equipped with a means for releasably securing the conversion piston holder to the free end of the spindle of the injection machine and also is equipped with a head for coupling the piston holder to the piston of a high-pressure syringe and for applying pressure to the piston of the manual syringe. The conversion piston holder replaces the original piston holder of the injection machine.

The conversion kit according to the present invention has the advantages of providing means to quickly, easily and inexpensively convert an injection machine designed for high-pressure syringes into an injection machine for manual

so syringes. Another advantage of the present invention is that the conversion is not permanent and the injection machine can easily be used for either high-pressure syringes of manual syringes. In one preferred embodiment of the present invention, the

55 conversion kit is designed for use with 30 ml to 50 ml manual injection syringes having similar diameters but which can differ in length and for 50 ml to 200 ml highpressure syringes.

In'another preferred embodiment, the conversion kit

60 according to the present invention includes a number of conversion vessels, a number of reducing sleeves and a number of piston-holders, so that the injection machine can be used for manual syringes having bodies which vary in diameter, e.g. for all or some selected sizes of manual

65 syringes having diameters ranging from 1 ml to 50 ml. In order to fit the reducing sleeve in the cylindrical guide of the head of the conversion vessel in a manner which

3 4

prevents shifting by small forces exerted during handling, FIG. 9 is a cross-section view of a conventional high

the conversion kit according to the present invention pressure syringe without the piston, along with a distal end

includes means for providing a resilient projection on the view thereof. In particular. FIG. 9 shows a high-pressure

inner periphery of the cylindrical guide of the injection syringe body, generally designated by reference numeral 1,

machine corresponding to a recess formed on the outer 5 having a cylinder 2. and a radially outward projecting

periphery of the reducing sleeve, or vice versa. In a particu- peripheral edge 3, in the form of a cylinder handle plate at

larly simple and convenient construction according to the the distal end of the cylinder 2.

present invention, the resilient projection is formed by an FIG. 10 is a cross-section view of a manual syringe

O-ring inserted into a groove formed on the inner periphery without the piston, and a distal end view thereof. In

of the guide or on the outer periphery of the reducing sleeve. 10 particular. FIG. 10 shows a manual syringe body, generally

The reducing sleeve of the conversion kit according to the designated by reference is numeral 4. having a cylinder 5.

present invention is preferably made of plastic, and particu- and a radially outward projecting peripheral edge 6, in the

larly a resilient plastic such as polytetrafluoroethylene, poly- form of a cylinder handle plate at the distal end of the

ester or polyamide. cylinder 5.

The present invention provides several advantages, some 15 As will be readily apparent from FIGS. 9 and 10. one

of which have been mentioned above and others which will difference between the high-pressure syringe body 1, and the

be described in detail with reference to a the drawing figures manual syringe body 4, is that the cylinder 5, of the manual

below. syringe body 4, has both a smaller inner and outer diameter

as compared with the cylinder 2, of the high-pressure

BRIEF DESCRIPTION OF THE DRAWINGS 20 syringe is primarily because the manual syringe

FIG. 1 is a partial diagrammatic view, mainly in cross- is designed for smaller volumes than the high-pressure

section, of an injection machine designed for high-pressure syringe. Consequently, the outer diameter of the piston (not

syringes, and including portions of the conversion kit shown) of the manual syringe is also smaller man the outer

according to the present invention. 25 diameter the piston (not shown) of the high-pressure

FIG. 2 is a cross-section view of the receiving head of a syringe,

conversion vessel for the conversion kit according to one A further difference between high-pressure syringes and

embodiment of the present invention. manual syringes is that the peripheral edge 6, of the manual

FIG. 3 is a perspective view of the bottom of the head of ^ 4' has a shaPe than of TMe

the conversion vessel shown in FIG. 2. i.e. showing the side 3o Puberal 3* of fte high-pressure syringe body 1. As

from which a preferably prefilled manual syringe is inserted shown m nG- 9< me peripheral edge 3. of the high-pressure

into the receiving head. syringe body 1, comprises a ring 7, which has diametrically

„_ . . .. ... , i-*A- opposite flat edges 8. The flat edges 8, interact with the

FIG. 4 is an cross-section view taken along line A—A in vv . x, 6 , . . . 7* * .....

HG. 5 of a reducing sleeve for a conversion kit according to f?*" m *e vessel of w ^wn machine to hold the

the present invention. 35 *frl!>*°«? TM » substantially non-rotatable posi

„ _ . , . tion when inserted into the injection machine, as will be

HG. 5 is a top view of the reducing sleeve shown in FIG. mQfe ^ described below. It is noted that some high

4, i.e. showing the side having the peripheral edge which is ^ s^ ^ onl one flat ed^e g Mso as shown

received by the recess in the head of the conversion vesse m mG 9 me edge 3, of ^ high-pressure syringe

and which receives (he distal peripheral edge of the manual body 1 has a rclativelv snort radial lengthi Le. me ^ 7< is

syTM^- 40 relatively narrow.

FIG. 6 is an cross-section view taken along Hoe R-B of ^ contrast as shown m mQ w me ^ heral ed 6 of

FIG. 7 of a porhon of a conversion piston holder for a ^ ^ ^ 4 has ^^3,^ opposite radial

conversion kit according to the present invention. projections or wings 9, having a relatively great axial length,

FIG. 7 is a top view of the conversion piston holder shown ^ i e me wings 9 w& relatively wide. The wings 9. of the

in FIG. 6, i.e. showing the side which faces the retractable manual syringe body 4, are generally considerably greater in

and extendable spindle of the injection machine. widm man me of me ring 7 of ^ high-pressure

FIG. 8 is a bottom view of the conversion piston holder syringe body 1, to facilitate easy manual handling of the

shown in FIG. 6, i.e. showing the side which contacts and manual syringe. Preferably, flat portions 6a, 6b, are provided

moves the piston of the manual syringe and which can be 5Q along a section of the peripheral edge 6, situated between the

releasably connected to the piston of a high-pressure wings 9, of the manual syringe body 4.

syringe. "With the above differences in mind, the conversion kit

FIG. 9 is a cross-section view of a high-pressure syringe according to the present invention will now be described

without the piston, along with a distal end view thereof. with reference to FIGS. 1-8. FIG. lis a partial diagrammatic

showing the shape of a peripheral edge radially projecting 55 view, mainly in cross-section, of an injection machine

from the high-pressure syringe body. designed for high-pressure syringes, and including portions

FIG. 10 is a cross-section view of a manual syringe of the conversion kit according to the present invention. For

without the piston, and a distal end view thereof, showing simplicity, FIG. 1 shows only the power-driven retractable

the shape of a distal radial peripheral edge including two and extendable spindle 10, of the injection machine which is

radially opposite wings. 60 used to move the piston of either a high-pressure syringe or

a manual syringe using the conversion kit of the present

DETAILED DESCRIPTION OF THE invention. In FIG. 1, the distal end region a manual syringe,

INVENTION generally designated by reference numeral 12, having a

Initially, the main differences between conventional piston 11, is shown,

manual syringes and high-pressure syringes, especially as 65 The conversion kit according to the present invention

such are important for understanding the present invention comprises a conversion vessel, generally designated by

will be discussed with reference to FIGS. 9 and 10. reference numeral 13. a reducing sleeve, generally desig

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