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(i9) United States

(12) Patent Application Publication

Kunjan et al.

US 20110009720A1

(io) Pub. No.: US 2011/0009720 Al (43) Pub. Date: Jan. 13, 2011

(54) CONTINUOUS WHOLE BLOOD GLUCOSE MONITOR

(76) Inventors: Kislaya Kunjan, Indianapolis, IN (US); Frank Perry Lloyd,

Indianapolis, IN (US)

Correspondence Address:
JAMES MINERVE
115 Saddle Blanket Trial
Buda, TX 78610 (US)

(21) Appl.No.: 11/982,565

(22) Filed: Nov. 2, 2007

Related U.S. Application Data

(60) Provisional application No. 60/856,456, filed on Nov. 2, 2006.

Publication Classification

(51) Int. CI.

A61B 5/00 (2006.01)
A61B 5/15 (2006.01)
A61M1/38 (2006.01)
A61M1/34 (2006.01)

(52) U.S. CI 600/316; 600/310; 600/581; 604/6.04;

604/6.09

(57) ABSTRACT

A portable continuous whole blood glucose monitor comprising, a mid-infrared quantum cascade laser and driver in optical communication with a transmission cell and a photoconductive detector and pre-amplifier. The monitor further comprises a peristaltic pump connected to a single lumen catheter peripherally inserted into a patient's vein. The single lumen catheter, in combination with the peristaltic pump, is operable to automatically withdraw a fixed and metered amount of whole blood from a patient, then a tube delivers a fixed and metered amount of the saline/surfactant supply to the whole blood. Methods of enhancing measurement sensitivity are also provided.

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