(19) United States
(12) Patent Application Publication (io) Pub. No.: US 2003/0032875 Al
Taniike et al. (43) Pub. Date: Feb. 13,2003
The present invention provides a highly sensitive biosensor that needs a smaller amount ol sample for measurement. The biosensor comprises a first insulating base plate having a working electrode, a second insulating base plate having a counter electrode opposed to the working electrode, a reagent layer comprising at least an oxidoreductase, and a sample supply pathway formed between the first and second insulating base plates, wherein the working electrode, counter electrode and reagent layer are exposed to an inside of the sample supply pathway, and the distance between the working electrode and the counter electrode is 150 fim or less.