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Page 10

Pirrung et al., "Proofing of Photolithographic DNA Synthesis with 3'.5'-Dimethoxybenzoinyloxycarbonyl-Protected Deoxynucleoside Phosphoramidites," /. Org. Chem., 63(2):241-246 (1998).

Pirrung et al., "Comparison of Methods for Photochemical Phosphoramidite-Based DNA Synthesis," /. Org. Chem., 60:6270-6276 (1995).

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Saiki et al., "Analysis of enzymatically amplified (3-globin and HLA-DQa DNA with Allele-specific oligonucleotide probes," Nature, 324:163-166 (1986). Scharf et al., "HLA class II allelic variation and susceptibility to pemphigus vulgaris," PNAS, 85(10):3504-3508 (1988).

Schuup et al., "Mechanistic Studies of the Photorearrangement of o-Nitrobenzyl Esters," /. Photochem., 36:85-97

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Seiler et al., "Planar Glass Chips for Capillary Electrophoresis: Repetitive Sample Injection, Quantitation, and Separation Efficency," Anal. Chem., 65:1481-1488 (1993).

Seller et al., "Electroosmotic Pumping and Valveless Con-
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Southern et al., "Report on the Sequencing by Hybridization Workshop," Genomics, 13:1378-1383 (1992). Southern et al., "Oligonucleotide hybridisations on glass supports: a novel linker for oligonucleotide synthesis and hybridization properties of oligonucleotides synthesized in situ," Nuc. Acids Res., 20(7):1679-1684 (1992). Southern et al., "Analyzing and Comparing Nucleic Acid Sequences by Hybridization to Arrays of Oligonucleotides: Evaluation Using Experimental Models," Genomics, 13:1008-10017 (1992).

Stemme et al., "A valveless diffuser/nozzle-based fluid pump," Sensors and Actuators, A39:159-167 (1993). Stryer, L., "DNA Probes and Genes Can be Synthesized by Automated Solid-Phase Methods," from Biochemistry, Third Edition, published by W.H. Freeman & Co., (1988). Stuber et al., "Synthesis and photolytic cleavage of bovine insulin B22-30 on a nitrobenzoylglycyl-poly (ethylene glycol) support," Int. J. Peptide Protein Res., 22(3):277-283 (1984).

Sundberg et al., "Spatially-Addressable Immobilization of Macromolecules on Solid Supports," /. Am. Chem. Soc, 117(49): 12050-12057 (1995).

Swedberg, S.A., "Use of non-ionic and zwitterionic surfactants to enhance selectivity in high-performance capillary electrophoresis, An apparent micellar electrokinetic capillary chromatography mechanism," /. Chromatography, 503:449^152 (1990).

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Tsien et al., "Control of Cytoplasmic Calcium with Photolabile Tetracarboxylate 2-Nitrobenzhydrol Chelators," Biophys. J., 50:843-853 (1986).

Tsutsumi et al., "Expression of L- and M- Type Pyruvate Kinase in Human Tissues," Genomics, 2:86-89 (1988).

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Turchinskii et al., "Multiple Hyridization in Genome Analysis Reaction of Diamines and Bisulfate with Cytosine for Introduction of Nonradioactive labels Into DNA," Molecular Biology, 22:1229-1235.

Turchinskii et al., "Multiple Hybridization in Genome Analysis, Reaction of Diamines and Bisulfate with Cytosine for Introduction of Nonradioactive labels Into DNA," Molecular Biology, 22:1229-1235 (1988). Turner et al., "Photochemical Activation of Acylated a-Thrombin," J. Am. Chem. Soc, 109:1274-1275 (1987). Urdea et al., "A novel method for the rapid detection of specific nucleotide sequences in crude biological samples without blotting or radioactivity; application to the analysis of hepatitis B virus in human serum," Gene, 61:253-264 (1987).

Urdea et al., "A comparison of non-radioisotopic hybridization assay methods using fluorescent, chemiluminescent and enzyme labeled synthetic oligodeoxyribonucleotide probes," Nuc. Acids Res., 16(ll):4937-4956 (1988). Van der Voort et al., "Design and Use of a Computer Controlled Confocal Microscope for Biological Applications," Scanning, 7(2):66-78 (1985). Van Hijfte et al., "Intramolecular 1,3-Diyl Trapping Reactions. A Formal Total Synthesis of -Coriolin," J. Organic Chemistry, 50:3942-3944 (1985).

Veldkamp, W.B., "Binary optics: the optics technology of the 1990s," CLEO 90, vol. 7, paper #CMG6 (1990). Verlaan-de Vries et al., "A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides," Gene, 50:313-320 (1986).

Verpoorte et al., "Three-dimensional micro flow manifolds for miniaturized chemical analysis systems," /. Micromech. Microeng., 4:246-256 (1994).

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Walker et al., "Photolabile Protecting Groups for an Acetylcholine Receptor Ligand. Synthesis and Photochemistry of a New Class of o-Nitrobenzyl Derivatives and their Effects on Receptor Function," Biochemistry, 25:1799-1805 (1986).

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Werner et al., "Size-Dependent Separation of Proteins Denatured in SDS by Capillary Electrophoresis Using a Replaceable Sieving Matrix," Anal. Biochem., 212:253-258 (1993).

White et al., "An Evaluation of Confocal Versus Conventional Imaging of Biological Structures by Fluorescence Light Microscopy,"/. Cell Biol, 105(1):41^8 (1987). Widacki et al., "Biochemical Differences in Qa-2 Antigens Expressed by Qa-2+,6+ and Qa-2a+,6- Strains. Evidence for Differential Expression of the Q7 and Q9 Genes," Mol. Immunology, 27(6):559-570 (1990).

Wilcox et al., "Synthesis of Photolabile 'Precursors' of Amino Acid Neurotransmitters," /. Org. Chem., 55:1585-1589 (1990).

Wilding et al, "PCR in a Silicon Microstructure," Clin. Chem., 40(9): 1815-1818 (1994).

Wilding et al., "Manipulation and Flow of Biological Fluids in Straight Channels Micromachined in Silicon," Clin. Chem., 40(l):43-47 (1994).

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Zehavi et al., "Light-Sensitive Glycosides. I. 6-Nitroveratryl (3-D-Glucopyranoside and 2-Nitrobenzyl (3-D-Glucopyranoside,"/. Org. Chem., 37(14):2281-2285 (1972). Zengerle et al., "Transient measurements on miniaturized diaphragm pumps in microfiuid systems," Sensors and Actuators, A46^7:557-561 (1995).

* cited by examiner

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