The invention is directed to methods and pharmaceutical compositions for the topical administration of analgesic drugs which affects peripheral muscarinic receptors such as neostigmine. In particular, the invention relates to topical administration of an analgesic agent, e.g., neostigmine, optionally...http://www.google.com.au/patents/US6011022?utm_source=gb-gplus-sharePatent US6011022 - Topical application of muscarinic analgesic drugs such as neostigmine