A novel approach for combining the ease of cleavage of carboxylic acid linker arms with the single phosphoramidite coupling chemistry of the universal supports useful in oligonucleotide synthesis. There is disclosed a new class of phosphoramidite reagents, linker phosphoramidites, which contain a bifunctional...http://www.google.com.au/patents/US20030036066?utm_source=gb-gplus-sharePatent US20030036066 - Linker phosphoramidites for oligonucleotide synthesis
