In accordance with the present invention, it has been discovered that introduction of hydrophilic sulfoalkyl substituents and/or hydrophilic linkers derived from homocysteic acid, cysteic acid, glycine peptides, tetraethylene oxide, and the like, offset the hydrophobicity of the acridinium ring system...http://www.google.com.au/patents/US7824928?utm_source=gb-gplus-sharePatent US7824928 - Hydrophilic chemiluminescent acridinium labeling reagents
