This invention relates to the manufacture of hydroxylapatite in a through-solution process wherein monobasic calcium phosphate is reacted with a calcium hydroxide solution. In a preferred embodiment, an acidic premix is formed by reacting phosphoric acid and calcium hydroxide with high shear agitation...http://www.google.com.au/patents/US4849193?utm_source=gb-gplus-sharePatent US4849193 - Process of preparing hydroxylapatite
