Catheter devices and methods are provided for enhancing fluid flow through a vascular site occupied by a calcified lesion. The catheter devices of the subject invention at least include, at their distal end, a proton generating means, and in many embodiments also include a flushing means. In using the...http://www.google.com.au/patents/US6719747?utm_source=gb-gplus-sharePatent US6719747 - Proton generating catheters and methods for their use in enhancing fluid flow through a vascular site occupied by a calcified vascular occulation