Variants of hedgehog protein that contain N-terminal modifications are described that can block hedgehog function; thus allowing these variants to serve as functional antagonists. These peptides have a primary amino acid sequence lacking the ability to elicit a hedgehog-dependent response in C3H 10T1/2...http://www.google.com.au/patents/US20030166543?utm_source=gb-gplus-sharePatent US20030166543 - Functional antagonists of hedgehog activity
