Non-human mammals comprising a disrupted MSH2 gene are disclosed. More particularly, animals having a disruption in one or both alleles of the MSH2 gene or a homolog of the MSH2 gene are disclosed. Animals homozygous for the disruption are viable past the embryonic stage of development but show an increased...http://www.google.com.au/patents/US5907079?utm_source=gb-gplus-sharePatent US5907079 - MSH2 disrupted mice develop lymphomas
