The invention relates to the induction of hematopoietic stem cells to differentiate into osteoclasts by culturing hematopoietic stem cells with human mesenchymal stem cells, and, in a preferred embodiment, using no exogenous cytokines. Differentiation of the mesenchymal stem cells into osteoblasts inhibited...http://www.google.com.au/patents/US6255112?utm_source=gb-gplus-sharePatent US6255112 - Regulation of hematopoietic stem cell differentiation by the use of human mesenchymal stem cells