A novel method of pyrophosphorolysis activated polymerization (PAP) has been developed. In PAP, pyrophosphorolysis and polymerization by DNA polymerase are coupled serially for each amplification by using an activatable oligonucleotide P* that has a non-extendible 3′-deoxynucleotide at its 3′ terminus....http://www.google.com.au/patents/US7238480?utm_source=gb-gplus-sharePatent US7238480 - Pyrophosphorolysis activated polymerization (PAP)
