Fluorescent dyes which are free of aggregation and serum binding are provided. These dyes are suitable for applications such as fluorescence immunoassays, in vivo imaging and in vivo tumor therapy. The dyes are particularly useful in fluorescence immunoassays of biological samples containing serum. Such...http://www.google.com.au/patents/US5641878?utm_source=gb-gplus-sharePatent US5641878 - Porphyrin, azaporphyrin, and related fluorescent dyes free of aggregation and serum binding