Nucleic acid affinity matrices that bear a large number of different nucleic acid affinity ligands allowing the simultaneous selection and removal of a large number of preselected nucleic acids from the sample. Methods of producing such affinity matrices are also provided. In general the methods involve...http://www.google.com.au/patents/US6440677?utm_source=gb-gplus-sharePatent US6440677 - Nucleic acid affinity columns