A method for closing a patent foramen ovale in the heart tissue of a patient may include percutaneously advancing a connector applicator to the patent foramen ovale, registering the connector applicator with the patent foramen ovale, deploying connectors into heart tissue to close the patent foramen...http://www.google.com.au/patents/US7875053?utm_source=gb-gplus-sharePatent US7875053 - Apparatus and method for closure of patent foramen ovale