The present invention provides a method and apparatus for dispensing a small volume of a selected liquid, such as a biological sample or reagent, onto a substrate. The device includes a tube adapted to contain the liquid. An elongate fiber is disposed within the tube for axial movement therein between...http://www.google.com.au/patents/US6296702?utm_source=gb-gplus-sharePatent US6296702 - Apparatus and method for spotting a substrate