This invention provides methods for determining whether a breast, prostate or ovarian tumor or tumor cell is aggressive, based on the quantitative measurement of p66-Shc and phosphorylated Shc. This invention also provides related methods of determining the likelihood of tumor recurrence. This invention...http://www.google.com.au/patents/US20040033542?utm_source=gb-gplus-sharePatent US20040033542 - Shc protein-related methods and compositions for the prognosis of breast, prostate and ovarian cancer