A two-component bone cement mixing system comprises a cartridge mixer having an interior volume containing a first predetermined quantity of a free-flowing, powdery, solid bone cement component under vacuum pressure; an ampoule containing a second predetermined quantity of a liquid bone cement component;...http://www.google.com.au/patents/US5100241?utm_source=gb-gplus-sharePatent US5100241 - Vacuum mixing/bone cement cartridge and kit