Methods for multiplex amplification of a plurality of targets of distinct sequence from a complex mixture are disclosed. In one aspect targets are circularized using a single circularization probe that is complementary to two regions in the target that flank a region to be amplified. The targets may...http://www.google.com.au/patents/US7862999?utm_source=gb-gplus-sharePatent US7862999 - Multiplex targeted amplification using flap nuclease