Disclosed is a method of diagnosing Alzheimer's disease in a patient by measuring the level of a lysosomal hydrolase or lysosomal protease inhibitor in the patient's cerebrospinal fluid. The invention also features methods of measuring the progression of the disease and screening therapeutic compositions...http://www.google.com.au/patents/US6130048?utm_source=gb-gplus-sharePatent US6130048 - Method of diagnosing Alzheimer's disease