A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 .mu.L. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. In...http://www.google.com.au/patents/US6143164?utm_source=gb-gplus-sharePatent US6143164 - Small volume in vitro analyte sensor