A method of preparing an immobilized oligonucleotide having a free 3'-end comprises the steps of: i) preparing an oligonucleotide attached in a first position to a solid support via its 3'-end and having a free 5'-end; ii) binding said oligonucleotide in a second position remote from the 3'-end to the...http://www.google.com.au/patents/US6313284?utm_source=gb-gplus-sharePatent US6313284 - Solid phase synthesis
