It has been shown that a 5' untranslated leader sequences of RNA virus non-structural genes act as enhancers of translation of mRNA. These leader sequences can be ligated upstream of an appropriate mRNA or used in the form of a cDNA expression vector. The translational enhancers are effective in many...http://www.google.com.au/patents/US5891665?utm_source=gb-gplus-sharePatent US5891665 - Untranslated leader sequences from RNA viruses as enhancers of translation