Solid controlled-release oral dosage forms comprising a therapeutically effective amount of an opioid analgesic or a salt thereof which provide an extended duration of pain relief of about 24 hours, have a dissolution rate in-vitro of the dosage form, when measured by the USP Paddle Method at 100 rpm...http://www.google.com.au/patents/US7740881?utm_source=gb-gplus-sharePatent US7740881 - Method of treating humans with opioid formulations having extended controlled release