WO2016156869A3 - Anti-microbial composition - Google Patents

Anti-microbial composition Download PDF

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Publication number
WO2016156869A3
WO2016156869A3 PCT/GB2016/050932 GB2016050932W WO2016156869A3 WO 2016156869 A3 WO2016156869 A3 WO 2016156869A3 GB 2016050932 W GB2016050932 W GB 2016050932W WO 2016156869 A3 WO2016156869 A3 WO 2016156869A3
Authority
WO
WIPO (PCT)
Prior art keywords
microbial
amino acid
salt
microbial composition
derivative
Prior art date
Application number
PCT/GB2016/050932
Other languages
French (fr)
Other versions
WO2016156869A2 (en
Inventor
Christopher Plummer
Rhiannon Sian HURD
Original Assignee
Byotrol Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byotrol Plc filed Critical Byotrol Plc
Priority to EP16719113.9A priority Critical patent/EP3277086A2/en
Priority to SG11201707755QA priority patent/SG11201707755QA/en
Priority to BR112017021002A priority patent/BR112017021002B8/en
Priority to CN201680020804.5A priority patent/CN107466207A/en
Priority to JP2017551246A priority patent/JP6785789B2/en
Publication of WO2016156869A2 publication Critical patent/WO2016156869A2/en
Publication of WO2016156869A3 publication Critical patent/WO2016156869A3/en
Priority to HK18105963.2A priority patent/HK1246088A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/32—Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N39/00—Biocides, pest repellants or attractants, or plant growth regulators containing aryloxy- or arylthio-aliphatic or cycloaliphatic compounds, containing the group or, e.g. phenoxyethylamine, phenylthio-acetonitrile, phenoxyacetone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

This invention relates to anti-microbial compositions comprising: an amino acid, a derivative of an amino acid, a salt of an amino acid, a salt of a derivative of an amino acid or mixtures thereof; an anti-microbial component comprising two or more anti-microbial quaternary ammonium compounds, or at least one anti-microbial quaternary ammonium compound and chlorhexidine or a salt thereof; and a polar solvent, and to formulations including the anti-microbial compositions. In particular, the invention relates to anti-microbial compositions that can be used on skin.
PCT/GB2016/050932 2015-04-02 2016-04-01 Anti-microbial composition WO2016156869A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP16719113.9A EP3277086A2 (en) 2015-04-02 2016-04-01 Anti-microbial composition
SG11201707755QA SG11201707755QA (en) 2015-04-02 2016-04-01 Anti-microbial composition
BR112017021002A BR112017021002B8 (en) 2015-04-02 2016-04-01 antimicrobial composition, use of a composition, method to substantially reduce or control the formation of microbial colonies on or on a surface, hand sanitizers, wound care product, personal care or hygiene product, pet product, and , antimicrobial tissue
CN201680020804.5A CN107466207A (en) 2015-04-02 2016-04-01 Antimicrobial compositions
JP2017551246A JP6785789B2 (en) 2015-04-02 2016-04-01 Antimicrobial composition
HK18105963.2A HK1246088A1 (en) 2015-04-02 2018-05-08 Anti-microbial composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1505701.1A GB201505701D0 (en) 2015-04-02 2015-04-02 Anti-microbial composition
GB1505701.1 2015-04-02

Publications (2)

Publication Number Publication Date
WO2016156869A2 WO2016156869A2 (en) 2016-10-06
WO2016156869A3 true WO2016156869A3 (en) 2016-11-10

Family

ID=53190097

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2016/050932 WO2016156869A2 (en) 2015-04-02 2016-04-01 Anti-microbial composition

Country Status (10)

Country Link
EP (1) EP3277086A2 (en)
JP (1) JP6785789B2 (en)
CN (1) CN107466207A (en)
BR (1) BR112017021002B8 (en)
GB (2) GB201505701D0 (en)
HK (1) HK1246088A1 (en)
MY (1) MY178425A (en)
SG (1) SG11201707755QA (en)
TW (1) TWI626006B (en)
WO (1) WO2016156869A2 (en)

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BR112018076819A2 (en) * 2016-06-24 2019-04-02 Lonza Inc. synergistic combination of biocides
GB201614087D0 (en) * 2016-08-17 2016-09-28 Byotrol Plc Anti-microbial composition
WO2018044840A1 (en) * 2016-08-31 2018-03-08 Cryovac, Inc. Synergistic cationic surfactants resulting in microbial inhibition on food surfaces and hard surfaces
MX2019003774A (en) * 2016-10-07 2019-07-01 Unilever Nv Personal wash disinfectant liquid.
KR101913718B1 (en) 2016-10-28 2018-11-01 주식회사 에이치피앤씨 Compositions for sterilization and disinfection comprising octenidine and benzalconium chloride
KR102591676B1 (en) 2016-12-16 2023-10-20 오로리움 홀딩스 엘엘씨 Quaternary amine formulations and their uses
US20190053493A1 (en) * 2017-08-18 2019-02-21 Lonza Inc. Premoistened Wipes With Virucidal Properties Against Non-Enveloped Viruses
RU2696259C2 (en) * 2017-10-23 2019-08-01 Общество С Ограниченной Ответственностью "Сан Системз" Solubilization of the chlorhexidine base, antiseptic and disinfectant compositions
WO2019104213A1 (en) * 2017-11-22 2019-05-31 Board Of Regents, The University Of Texas System Antibiofilm formulations and use thereof
EP3543396B1 (en) * 2018-03-19 2021-12-15 Livinguard AG Organic antimicrobial textile
CN111954733A (en) * 2018-03-19 2020-11-17 生活保卫股份公司 Organic antibacterial textile
KR20200130486A (en) * 2018-04-09 2020-11-18 로디아 오퍼레이션스 Composition and method for long lasting disinfection
MX2020010993A (en) * 2018-04-19 2020-12-09 Ucar Health Gmbh Surface, air, textile, paint, plastic, silicone and wood, polyethylene; metal and derivatives antimicrobial properties.
CN110317684B (en) * 2018-06-22 2021-05-25 华东师范大学 Natural environment-friendly nontoxic kitchen oil stain cleaning agent
TWI711469B (en) * 2018-09-10 2020-12-01 寶齡富錦生技股份有限公司 Antimicrobial composition and preparation method thereof
CN109169653B (en) * 2018-10-24 2020-09-29 湖北荷普药业股份有限公司 Cation composite disinfectant and application thereof
AU2018451180A1 (en) * 2018-11-30 2021-06-03 Ucar Health Gmbh Woven, nonwoven, cotton, nonwoven-cotton blended polyethylene and polipropilen and polystyrene mask, wound dressing, panty, bra, handkerchief, pad, scouring pad, disposable surgical dress, disposable sheets with antimicrobial properties
US11889832B2 (en) 2019-05-17 2024-02-06 Ecolab Usa Inc. Antimicrobial enhancement of cationic active skin antiseptics
CN111616148A (en) * 2020-05-28 2020-09-04 江苏雪豹日化有限公司 High-efficiency disinfectant
GB202012191D0 (en) * 2020-08-05 2020-09-16 Byotrol Plc Anti-microbial composition
CN112294789B (en) * 2020-10-15 2022-06-07 郑涛 Compound preparation for preventing and treating respiratory tract infection and application thereof
CN113100085B (en) * 2021-04-21 2023-12-22 铜陵博锋实业有限公司 Transparent high-water-absorptivity starch cat litter and preparation process thereof
CN115299437A (en) * 2021-05-06 2022-11-08 南顺商标有限公司 Antimicrobial compositions and methods of making the same
US11707867B1 (en) * 2021-07-30 2023-07-25 Csr Worldwide Ok, Inc. System for handling used packaging film in a food processing facility
CN113796385B (en) * 2021-10-13 2023-05-30 洛阳冠银生物科技有限公司 Silver ion-containing chlorhexidine salt compound and preparation method and application thereof
CN115119841A (en) * 2022-07-29 2022-09-30 厦门兴勒贸易有限公司 Novel chitosan composite cationic disinfectant suitable for high-power dilution
KR102536496B1 (en) * 2022-09-30 2023-06-01 서강대학교 산학협력단 a passive sampler for measuring concentration of sprayed quaternary ammonium salt in air and a method for measuring concentration of sprayed quaternary ammonium salt using same

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Also Published As

Publication number Publication date
HK1246088A1 (en) 2018-09-07
BR112017021002B8 (en) 2020-06-16
MY178425A (en) 2020-10-13
GB201505701D0 (en) 2015-05-20
WO2016156869A2 (en) 2016-10-06
GB2533527A (en) 2016-06-22
TW201709819A (en) 2017-03-16
BR112017021002B1 (en) 2020-05-26
BR112017021002A2 (en) 2018-07-03
TWI626006B (en) 2018-06-11
EP3277086A2 (en) 2018-02-07
SG11201707755QA (en) 2017-10-30
CN107466207A (en) 2017-12-12
JP6785789B2 (en) 2020-11-18
GB2533527B (en) 2018-10-17
JP2018511607A (en) 2018-04-26

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