WO2015073538A3 - Interaction with metalloenzymes - Google Patents

Interaction with metalloenzymes Download PDF

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Publication number
WO2015073538A3
WO2015073538A3 PCT/US2014/065221 US2014065221W WO2015073538A3 WO 2015073538 A3 WO2015073538 A3 WO 2015073538A3 US 2014065221 W US2014065221 W US 2014065221W WO 2015073538 A3 WO2015073538 A3 WO 2015073538A3
Authority
WO
WIPO (PCT)
Prior art keywords
metalloenzymes
interaction
peptides
compositions
treatment
Prior art date
Application number
PCT/US2014/065221
Other languages
French (fr)
Other versions
WO2015073538A2 (en
Inventor
Jennifer Ann STOWELL LAURENCE
Paulette Spencer
George Laurence
Original Assignee
Echogen, Inc.
University Of Kansas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Echogen, Inc., University Of Kansas filed Critical Echogen, Inc.
Publication of WO2015073538A2 publication Critical patent/WO2015073538A2/en
Publication of WO2015073538A3 publication Critical patent/WO2015073538A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids

Abstract

Compositions comprising peptides that are capable of inhibiting metalloenzymes are disclosed. The peptides can be used for the treatment of cancers associated with metalloenzymes.
PCT/US2014/065221 2013-11-12 2014-11-12 Interaction with metalloenzymes WO2015073538A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361903303P 2013-11-12 2013-11-12
US61/903,303 2013-11-12

Publications (2)

Publication Number Publication Date
WO2015073538A2 WO2015073538A2 (en) 2015-05-21
WO2015073538A3 true WO2015073538A3 (en) 2015-11-12

Family

ID=53058248

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/065221 WO2015073538A2 (en) 2013-11-12 2014-11-12 Interaction with metalloenzymes

Country Status (1)

Country Link
WO (1) WO2015073538A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7400727B2 (en) 2018-10-10 2023-12-19 味の素株式会社 Extracellular matrix degrading enzyme inhibitor

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698671A (en) * 1989-03-21 1997-12-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Metalloproteinase peptides
US5872152A (en) * 1992-05-01 1999-02-16 British Biotech Pharmaceuticals Limited Use of MMP inhibitors
US20030073808A1 (en) * 2000-12-29 2003-04-17 Stephen Quirk Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases
WO2009000971A2 (en) * 2007-06-25 2008-12-31 Licentia Oy A novel peptide

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698671A (en) * 1989-03-21 1997-12-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Metalloproteinase peptides
US5872152A (en) * 1992-05-01 1999-02-16 British Biotech Pharmaceuticals Limited Use of MMP inhibitors
US20030073808A1 (en) * 2000-12-29 2003-04-17 Stephen Quirk Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases
WO2009000971A2 (en) * 2007-06-25 2008-12-31 Licentia Oy A novel peptide

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KOIVUNEN ET AL.: "Tumor targeting with a selective gelatinase inhibitor", NATURE BIOTECHNOLOGY, vol. 17, 1 August 1999 (1999-08-01), pages 768 - 774, XP000941541 *

Also Published As

Publication number Publication date
WO2015073538A2 (en) 2015-05-21

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