WO2015021304A3 - Carotid body ablation via directed energy - Google Patents

Carotid body ablation via directed energy Download PDF

Info

Publication number
WO2015021304A3
WO2015021304A3 PCT/US2014/050189 US2014050189W WO2015021304A3 WO 2015021304 A3 WO2015021304 A3 WO 2015021304A3 US 2014050189 W US2014050189 W US 2014050189W WO 2015021304 A3 WO2015021304 A3 WO 2015021304A3
Authority
WO
WIPO (PCT)
Prior art keywords
carotid body
body ablation
directed energy
via directed
ablation via
Prior art date
Application number
PCT/US2014/050189
Other languages
French (fr)
Other versions
WO2015021304A2 (en
Inventor
Yegor D. SINELNIKOV
Original Assignee
Cibiem, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cibiem, Inc. filed Critical Cibiem, Inc.
Priority to EP14833876.7A priority Critical patent/EP3030167A4/en
Publication of WO2015021304A2 publication Critical patent/WO2015021304A2/en
Publication of WO2015021304A3 publication Critical patent/WO2015021304A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A61N7/022—Localised ultrasound hyperthermia intracavitary
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/24—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0891—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/488—Diagnostic techniques involving Doppler signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3478—Endoscopic needles, e.g. for infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003—Steerable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
    • A61B2018/00279—Anchoring means for temporary attachment of a device to tissue deployable
    • A61B2018/00285—Balloons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B2018/2005—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser with beam delivery through an interstitially insertable device, e.g. needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/378—Surgical systems with images on a monitor during operation using ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0833—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures
    • A61B8/0841—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures for locating instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0004—Applications of ultrasound therapy
    • A61N2007/0021—Neural system treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0086—Beam steering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0086—Beam steering
    • A61N2007/0091—Beam steering with moving parts, e.g. transducers, lenses, reflectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0086—Beam steering
    • A61N2007/0095—Beam steering by modifying an excitation signal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A61N2007/025—Localised ultrasound hyperthermia interstitial

Abstract

Methods and devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation.
PCT/US2014/050189 2013-08-07 2014-08-07 Carotid body ablation via directed energy WO2015021304A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP14833876.7A EP3030167A4 (en) 2013-08-07 2014-08-07 Carotid body ablation via directed energy

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201361863392P 2013-08-07 2013-08-07
US61/863,392 2013-08-07
US201361874280P 2013-09-05 2013-09-05
US61/874,280 2013-09-05
US201361910765P 2013-12-02 2013-12-02
US61/910,765 2013-12-02

Publications (2)

Publication Number Publication Date
WO2015021304A2 WO2015021304A2 (en) 2015-02-12
WO2015021304A3 true WO2015021304A3 (en) 2015-04-09

Family

ID=52462043

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/050189 WO2015021304A2 (en) 2013-08-07 2014-08-07 Carotid body ablation via directed energy

Country Status (2)

Country Link
EP (1) EP3030167A4 (en)
WO (1) WO2015021304A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108135579B (en) * 2015-10-22 2020-08-14 株式会社日立制作所 Ultrasonic diagnostic apparatus and attenuation characteristic measuring method

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112013002175T5 (en) 2012-04-24 2015-01-22 Cibiem, Inc. Endovascular catheters and procedures for ablation of the carotid body
EP3116408B1 (en) 2014-03-12 2018-12-19 Cibiem, Inc. Ultrasound ablation catheter
EP3268075A4 (en) * 2015-03-12 2018-11-14 Cibiem, Inc. Carotid septum ablation with ultrasound imaging and ablation catheters
GB201510663D0 (en) * 2015-06-17 2015-07-29 Isis Innovation Support apparatus
WO2017044961A1 (en) * 2015-09-11 2017-03-16 Cibiem, Inc. Carotid body ablation with a transvenous ultrasound imaging and ablation catheter
CN106037803B (en) * 2016-06-27 2023-09-01 中国科学院苏州生物医学工程技术研究所 Ultrasonic transducer array, ultrasonic interventional therapy system and ultrasonic ablation catheter
CN108853751A (en) * 2017-05-12 2018-11-23 南京中硼联康医疗科技有限公司 Photon emits detection device and the boron neutron capture treatment system with it

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5139496A (en) * 1990-12-20 1992-08-18 Hed Aharon Z Ultrasonic freeze ablation catheters and probes
US5906580A (en) * 1997-05-05 1999-05-25 Creare Inc. Ultrasound system and method of administering ultrasound including a plurality of multi-layer transducer elements
US6544187B2 (en) * 1999-03-31 2003-04-08 Mayo Foundation For Medical Education And Research Parametric imaging ultrasound catheter
US20120172680A1 (en) * 2010-12-28 2012-07-05 G & L Consulting, Llc Method for sympathetic rebalancing of patient

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5431621A (en) * 1984-11-26 1995-07-11 Edap International Process and device of an anatomic anomaly by means of elastic waves, with tracking of the target and automatic triggering of the shootings
US5435311A (en) 1989-06-27 1995-07-25 Hitachi, Ltd. Ultrasound therapeutic system
DE69634714T2 (en) 1995-03-31 2006-01-19 Kabushiki Kaisha Toshiba, Kawasaki Therapeutic ultrasound device
US6425867B1 (en) 1998-09-18 2002-07-30 University Of Washington Noise-free real time ultrasonic imaging of a treatment site undergoing high intensity focused ultrasound therapy
US7499742B2 (en) 2001-09-26 2009-03-03 Cvrx, Inc. Electrode structures and methods for their use in cardiovascular reflex control
US7162303B2 (en) 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US7149574B2 (en) 2003-06-09 2006-12-12 Palo Alto Investors Treatment of conditions through electrical modulation of the autonomic nervous system
US7738952B2 (en) 2003-06-09 2010-06-15 Palo Alto Investors Treatment of conditions through modulation of the autonomic nervous system
WO2010019481A1 (en) 2008-08-11 2010-02-18 Conceptx Medical, Inc. Systems and methods for treating dyspnea, including via electrical afferent signal blocking

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5139496A (en) * 1990-12-20 1992-08-18 Hed Aharon Z Ultrasonic freeze ablation catheters and probes
US5906580A (en) * 1997-05-05 1999-05-25 Creare Inc. Ultrasound system and method of administering ultrasound including a plurality of multi-layer transducer elements
US6544187B2 (en) * 1999-03-31 2003-04-08 Mayo Foundation For Medical Education And Research Parametric imaging ultrasound catheter
US20120172680A1 (en) * 2010-12-28 2012-07-05 G & L Consulting, Llc Method for sympathetic rebalancing of patient

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP3030167A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108135579B (en) * 2015-10-22 2020-08-14 株式会社日立制作所 Ultrasonic diagnostic apparatus and attenuation characteristic measuring method

Also Published As

Publication number Publication date
EP3030167A4 (en) 2017-03-22
EP3030167A2 (en) 2016-06-15
WO2015021304A2 (en) 2015-02-12

Similar Documents

Publication Publication Date Title
WO2015138795A8 (en) Carotid body ablation with a transvenous ultrasound imaging and ablation catheter
WO2015021304A3 (en) Carotid body ablation via directed energy
WO2014150817A3 (en) Method and system to predict response to treatments for mental disorders
MX2021002728A (en) Combination of anti-lag-3 antibodies and anti-pd-1 antibodies to treat tumors.
EP3405251A4 (en) Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
HK1225623A1 (en) Compositions, methods and kits for diagnosing and treating cd206 expressing cell-related disorders
EP3111317A4 (en) Transferring authorization from an authenticated device to an unauthenticated device
MX2018010548A (en) Dll3 modulators and methods of use.
EP3005203A4 (en) System and method for credential authentication
PH12014501914B1 (en) Anti sez6 antibodies and methods of use
WO2013056148A3 (en) Scd1 antagonists for treating cancer
WO2013119960A3 (en) Anti-cd324 monoclonal antibodies and uses thereof
MX363654B (en) Authentication in device to device discovery.
WO2014165090A8 (en) Compounds for the treatment of tuberculosis
TWD175663S (en) Rack system
MX2016008516A (en) Therapeutic methods and compositions.
GB201411274D0 (en) Improvements in and relating to neurostimulating devices for treating pain, improving function and other nervous system related conditions.
EP2991387A4 (en) Vehicle acoustic control device, and vehicle acoustic control method
PH12015502713B1 (en) Method for upregulating antigen expression
SG10201804034QA (en) Methods for treating hypotension
MX2015013066A (en) Therapeutic uses for vegfr1 antibodies.
EP3137082A4 (en) Methods to treat, prevent, and improve skin conditions
MX356933B (en) Composition and method for the diagnosis and treatment of iron-related disorders.
EP3142382A4 (en) Method, apparatus and system for supplying power to active noise cancelling earphone
GB2554624B (en) Process for the Treatment of Ashes and Digestates, Treated Ashes and Digestates thus obtained and uses thereof.

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 14833876

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2014833876

Country of ref document: EP

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 14833876

Country of ref document: EP

Kind code of ref document: A2