WO2015008101A1 - Composition of a drink for enhanced reduction of blood alcohol level - Google Patents
Composition of a drink for enhanced reduction of blood alcohol level Download PDFInfo
- Publication number
- WO2015008101A1 WO2015008101A1 PCT/IB2013/001535 IB2013001535W WO2015008101A1 WO 2015008101 A1 WO2015008101 A1 WO 2015008101A1 IB 2013001535 W IB2013001535 W IB 2013001535W WO 2015008101 A1 WO2015008101 A1 WO 2015008101A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- drink
- blood alcohol
- alcohol
- composition
- vitamin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
Definitions
- Composition of a Drink for Enhanced Reduction of Blood Alcohol Level .
- the invention relates to a combination of ingredients for a fitness drink and more exactly to a combination of enzymes which enhance the liver metabolism of alcohol, added by fructose and caffeine and similar agents to accelerate so- matic reaction.
- ADH alcohol dehydrogenases
- US 7.544356 B2 proposes Lactobacillus brevis HY 7401 , Lactobellis fermentum CS332, Lactobacillus acidophilus CSG, Bifidobacterium Longum HY 8001 , Alder treee extract, selfheal extract, a milk thistle extract, bean-rice bran fermentation extract, turnip, -tomato, pinapple and broccoli extract, whereas the extract from artichoke, well-known for its curative effect on the human liver, and main ingredient in allegedly alcohol reducing drink "security" (http://securityfeelbetter.com), was not indicated in patent literature. DESCRIPTION OF THE INVENTION
- ADHs develop their catalytic effect particularly in a balanced aquae- ous solution.
- Direct exposition to gastric acid may be the reason, why alcohol- reducing medicaments for oral application had only poor effect.
- the idea therefore is to combine it with a drink, where ADHs can fulfil their catalytic effect due to the predetermined aqueous mix.
- the other inventive step is the combination of these enzymes with fructose, as known from prior art.
- fructose is not only stimulating the liver metabolism.
- its complementary effect is used to sweeten the bitter enzymes and added fruit acids and to stabilize the ADH component.
- arginines and asparagines may be added to enhance the metabolism, particularly the discharge of ammonia residues, as well as fumaric acids, which are known for reducing hangover effects by stimulating the citric acid cycle.
- Phenylalanine naturally found in the breast milk of mammals. It is reputed for its analgesic and antidepressant effects. It is a direct precursor to the neuromodulator phenylethylamine, a commonly used dietary supplement.
- L-arginine may be added, which also helps rid the body of ammonia (a waste product) and stimulates the release of insulin.
- L-arginine is used to enhance the delivery of nitric oxide (a compound that relaxes the blood vessels) and therefore may reduce headaches.
- Further embodiments may enclose caffeines, e.g. Guarana to further enhance physical activity, mineral nutriments and adapted flavors to make a recovering drink.
- the composition therefore may contain in each 200 mililiter drink a composition of: Fructoses 40.000 - 8000 mg
- Lower curve is with and upper curve without consummation of 250 ml of the here disclosed mixture at 21 :30 h.
Abstract
Composition of a Drink for Enhanced Reduction of Blood Alcohol Level. A fitness drink for enhancing reduction of blood alcohol comprising ADH (Alcohol dehydrogenases) is sweetened with high dosis of fructose and recharged with malic acid, fumaric acid, arginine, phenylalanine, asparagine, ascorbic acid, vitamin Bl, vitamin B6 and caffeine.
Description
Composition of a Drink for Enhanced Reduction of Blood Alcohol Level .
FIELD OF THE INVENTION
The invention relates to a combination of ingredients for a fitness drink and more exactly to a combination of enzymes which enhance the liver metabolism of alcohol, added by fructose and caffeine and similar agents to accelerate so- matic reaction.
BACKGROUND OF THE INVENTION
The use of alcohol may ease communication with reducing tensions and psychi- cal inhibitions and therefore is frequently consumed on parties, reunions and in discotheques.
But not only a hangover in cases of over-consumption may be the consequence, the strongly reduced ability to safely drive a car jeopardizes even social drinkers to an inacceptable extent.
However, even strong intent to keep from too much drinking might be foiled by social effects, as the need to accept invitations, etc.
Thus, there may be a need of quite quickly to reduce blood alcohol , particularly if there is only a short period of rest or sleep before re-entering into commuting and returning to business.
It is well known, that there are amino acids, as phenylalanine and asparagine that enhance the liver metabolism and that it is alcohol dehydrogenases (ADH) in the liver and stomach, which breaks down alcohol directly. The amount of ADH represented in the human body is recognized responsible for interpersonal and interracial differences of toxic reactions to alcohol . However, these enzymes are only effectively deployed in a watery dilution, and ADH may be instable at particular conditions. Furthermore, almost all of these enzymes taste extremely bitter and therefore are not used in drinks sofar.
There are other substances known to enhance reduction of blood alcohol , like maltodextrine, which recondition the anterior cingular cortex to stimulate physical activity and therewith may help to reduce effects of alcohol . But this as well is quite untasty.
Therefore it is the task of the here disclosed invention to create a drink, that helps to quickly reduce the blood alcohol level in terms of a dietary supplement, but has acceptable taste.
PRIOR ART
There are quite a few propositions known to reduce blood alcohol while drinking, as in WO2002055093 A2 . with swallowing limestone and activated chara- coal , active dry yeast (WO 20003006642 A 1) or edible crystal zeolite (WO 12987000049 A 1) -where people could wonder, what for then to drink alcohol .
But most propositions refer to reducing the alcohol level after drinking, wether by injections with enzyme alcohol oxidase (US 54.450.153 A) or Potassium sorbate) and later indicated standard ingredients in EP 2223817, or again by swallowing dry yeast (EP 1412490 Al) or charcoal (EP0264430 Al) or food preparations with potassium bitartrate and sodium bicarbonate (EP 2172115 Al), or compositions with animal glandular extract, again yeast and bacterial extracts and divers plant extracts (WO 2005123099 A2).
However, since the side effects of alcohol, particularly hangover, are closely related to corporal dehydration, application of active agents are preferably administered in drinks. So almost all of the following formulations contain water and fructose, which is known for enhancing liver metabolism and is commonly used as sweetening agent, furthermore vitamins, particularly of the B6 and B 12 group and Vitamin C:
US 6.514.544 B2 and WO 20000030477 Al are simply adding taurine to that, as others use cafeine to enhance metabolism, whereas EP 0205634 B l additionally proposes quinine, sodium chloride and tripoassium citrate, and EP 0631778 A l relies on L-aspartate or L-asparagine, the effects of which on blood alcohol are quite antithetically discussed in the scientific community.
A few other rather exotic ingredients, the evaluation of which is not possible here, is besides saccarides (which are less expensive, but poorly active in liver metabolism compared to fructose) and sodium ion a plus Yacon Syrop, another sugar substitute (EP 2323693 B l), Kudzu and Nopal (sofar only known as Mexican vegetable, a cactus specimen) and white willow bark extract, named beside N-acetyl cysteine in WO 20120558589 Al . US 7.544356 B2 proposes Lactobacillus brevis HY 7401 , Lactobellis fermentum CS332, Lactobacillus acidophilus CSG, Bifidobacterium Longum HY 8001 , Alder treee extract, selfheal extract, a milk thistle extract, bean-rice bran fermentation extract, turnip, -tomato, pinapple and broccoli extract, whereas the extract from artichoke, well-known for its curative effect on the human liver, and main ingredient in allegedly alcohol reducing drink "security" (http://securityfeelbetter.com), was not indicated in patent literature.
DESCRIPTION OF THE INVENTION
One idea therefore was stimulated by the drop in prices for ADHs, which formerly had to be extracted from horse livers and -due to low yield- were quite expensive.
Since their demand rose sharply for catalysts to the synthesis of fuels from bio- mass, biotechnological methods have been developed, particularly their extraction from modified yeast, that might allow their application in consumer products.
However, ADHs develop their catalytic effect particularly in a balanced aquae- ous solution. Direct exposition to gastric acid may be the reason, why alcohol- reducing medicaments for oral application had only poor effect.
The idea therefore is to combine it with a drink, where ADHs can fulfil their catalytic effect due to the predetermined aqueous mix.
The other inventive step is the combination of these enzymes with fructose, as known from prior art. In an accordingly high dosage fructose is not only stimulating the liver metabolism. Here its complementary effect is used to sweeten the bitter enzymes and added fruit acids and to stabilize the ADH component.
In another developmental step arginines and asparagines may be added to enhance the metabolism, particularly the discharge of ammonia residues, as well as fumaric acids, which are known for reducing hangover effects by stimulating the citric acid cycle.
Other enhancing effects are known from Phenylalanine, naturally found in the breast milk of mammals. It is reputed for its analgesic and antidepressant effects. It is a direct precursor to the neuromodulator phenylethylamine, a commonly used dietary supplement.
Moreover ascorbic acid, well proven for reducing side-effects of alcohol, that provoke hangover, and L-arginine may be added, which also helps rid the body of ammonia (a waste product) and stimulates the release of insulin. In addition, L-arginine is used to enhance the delivery of nitric oxide (a compound that relaxes the blood vessels) and therefore may reduce headaches. Further embodiments may enclose caffeines, e.g. Guarana to further enhance physical activity, mineral nutriments and adapted flavors to make a recovering drink.
The composition therefore may contain in each 200 mililiter drink a composition of:
Fructoses 40.000 - 8000 mg
Phenylalanine 600 - 800 mg
Asparagine/Paraxine 500 - 700 mg
Fumaric Acid 300 - 500 mg
ADH 5 - 10 mg
Malic acid 250 - 400 mg
Arginine 700 - 1.000 mg
Its to be stated, that these agents and their dosage are meeting EU-regulation 2002/46/EG and the German LFGB for dietary supplements, whereas in USA the FDA would allow higher dosages and even claims for therapeutic application.
DESCRIPTION OF THE DRAWING
Figl demonstrates the physical effects of the here disclosed drink on a human body:
It shows the averaged relative blood alcohol level in per mil of 15 male test persons, quite equally mixed from 19 up to 70 years, the night after consummation of each one bottle (3/4 liters) of red wine between 20:30 and 21 :30, measured consecutively each 1/2 hour after 22:00 h.
Lower curve is with and upper curve without consummation of 250 ml of the here disclosed mixture at 21 :30 h.
Claims
1. A Fitness drink for quickly reducing blood alcohol , comprising the follow components in 200 ml carbonized water at the given dosage range of:
Fructoses 40.000 - 8000 mg
ADH 5 - 10 mg
2. A Fitness drink according to claim 1 , further containing:
Malic acid 250 - 400 mg
Arginine 700 - 1.000 mg
Phenylalanine 600 - 800 mg
A sparagi ne/Paraxi ne 500 - 700 mg
Fumaric acid 300 - 500 mg
Ascorbic acid 200 - 400 mg
Vitamin B l 2 - 4 mg
Vitamin B6 1 - 3 mg
Caffeine 40 - 70 mg
Fructal flavoring ad lib.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IB2013/001535 WO2015008101A1 (en) | 2013-07-15 | 2013-07-15 | Composition of a drink for enhanced reduction of blood alcohol level |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IB2013/001535 WO2015008101A1 (en) | 2013-07-15 | 2013-07-15 | Composition of a drink for enhanced reduction of blood alcohol level |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2015008101A1 true WO2015008101A1 (en) | 2015-01-22 |
Family
ID=49034115
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2013/001535 WO2015008101A1 (en) | 2013-07-15 | 2013-07-15 | Composition of a drink for enhanced reduction of blood alcohol level |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2015008101A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016036254A1 (en) * | 2014-09-03 | 2016-03-10 | Kystvågen Slip & Mek As | Crawler configured for submarine use |
Citations (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4450153A (en) | 1982-09-30 | 1984-05-22 | Phillips Petroleum Company | Alcohol removal from blood with alcohol oxidase |
WO1987000049A1 (en) | 1985-07-02 | 1987-01-15 | Gatehouse Technical Ventures Limited | Adsorbent composition |
EP0205634B1 (en) | 1985-06-24 | 1988-03-02 | Manfred Bannes | Beverage containing fructose, vitamin c, quinine and/or derivatives thereof |
EP0264430A1 (en) | 1986-04-14 | 1988-04-27 | MARGOLIN, Ely | Composition and method for reducing blood alcohol content |
EP0631778A1 (en) | 1993-06-28 | 1995-01-04 | Miwon Co., Ltd. | Use of L-aspartate or L-asparagine to prevent alcohol toxicity |
WO2000030477A1 (en) | 1998-11-19 | 2000-06-02 | Norbert Fuchs | Beverage for increasing the body's capacity to break down alcohol |
CN1279111A (en) * | 1999-06-23 | 2001-01-10 | 詹莉 | Nutritive bioenzyme liquor for sobering up and its preparing process |
WO2002055093A2 (en) | 2001-01-12 | 2002-07-18 | Innovation Ventures, Llc | Activated charcoal based composition and method for reducing hangover symptoms associated with the consumption of alcohol containing beverages |
WO2003006642A1 (en) | 2000-02-25 | 2003-01-23 | Owades Joseph L | Mediating the effects of alcohol consumption by orally administering active dry yeast |
EP1412490A1 (en) | 2001-07-11 | 2004-04-28 | Joseph L. Owades | Mediating the effects of alcohol consumption by orally administering active dry yeast |
WO2005123099A2 (en) | 2004-06-08 | 2005-12-29 | Enzymedix, Inc. | Methods and compositions for accelerating alcohol metabolism |
US7544356B2 (en) | 2005-04-19 | 2009-06-09 | Korea Yakult Co., Ltd. | Composition for the improvement of liver function, the reduction of serum ethanol level and antioxidant activity enhancement |
KR20090091653A (en) * | 2008-02-25 | 2009-08-28 | 주식회사 기영약품 | Composition for relieving and preventing hangover |
EP2172115A1 (en) | 2008-10-03 | 2010-04-07 | Ivan Biffi | Composition for use in the reduction of blood alcohol content |
EP2223817A2 (en) | 2009-02-27 | 2010-09-01 | Magna Car Top Systems GmbH | Locking device for a cabriolet roof |
WO2012058589A1 (en) | 2010-10-28 | 2012-05-03 | Jonathan Burg | Compositions and methods to reduce hangover and reduce blood alcohol levels after alcohol consumption |
WO2012091251A1 (en) * | 2010-12-27 | 2012-07-05 | 순천대학교 산학협력단 | Drink composition for hangover relief, containing cucumber vinegar |
EP2323692B1 (en) | 2008-09-04 | 2013-04-24 | Early Bird Drinks B.V. | Hangover relief by compositions comprising oral rehydration solution |
-
2013
- 2013-07-15 WO PCT/IB2013/001535 patent/WO2015008101A1/en active Application Filing
Patent Citations (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4450153A (en) | 1982-09-30 | 1984-05-22 | Phillips Petroleum Company | Alcohol removal from blood with alcohol oxidase |
EP0205634B1 (en) | 1985-06-24 | 1988-03-02 | Manfred Bannes | Beverage containing fructose, vitamin c, quinine and/or derivatives thereof |
WO1987000049A1 (en) | 1985-07-02 | 1987-01-15 | Gatehouse Technical Ventures Limited | Adsorbent composition |
EP0264430A1 (en) | 1986-04-14 | 1988-04-27 | MARGOLIN, Ely | Composition and method for reducing blood alcohol content |
EP0631778A1 (en) | 1993-06-28 | 1995-01-04 | Miwon Co., Ltd. | Use of L-aspartate or L-asparagine to prevent alcohol toxicity |
WO2000030477A1 (en) | 1998-11-19 | 2000-06-02 | Norbert Fuchs | Beverage for increasing the body's capacity to break down alcohol |
US6514544B2 (en) | 1998-11-19 | 2003-02-04 | Jhs-Privatstiftung | Beverage for increasing the body's capacity to break down alcohol and method thereof |
CN1279111A (en) * | 1999-06-23 | 2001-01-10 | 詹莉 | Nutritive bioenzyme liquor for sobering up and its preparing process |
WO2003006642A1 (en) | 2000-02-25 | 2003-01-23 | Owades Joseph L | Mediating the effects of alcohol consumption by orally administering active dry yeast |
WO2002055093A2 (en) | 2001-01-12 | 2002-07-18 | Innovation Ventures, Llc | Activated charcoal based composition and method for reducing hangover symptoms associated with the consumption of alcohol containing beverages |
EP1412490A1 (en) | 2001-07-11 | 2004-04-28 | Joseph L. Owades | Mediating the effects of alcohol consumption by orally administering active dry yeast |
WO2005123099A2 (en) | 2004-06-08 | 2005-12-29 | Enzymedix, Inc. | Methods and compositions for accelerating alcohol metabolism |
US7544356B2 (en) | 2005-04-19 | 2009-06-09 | Korea Yakult Co., Ltd. | Composition for the improvement of liver function, the reduction of serum ethanol level and antioxidant activity enhancement |
KR20090091653A (en) * | 2008-02-25 | 2009-08-28 | 주식회사 기영약품 | Composition for relieving and preventing hangover |
EP2323692B1 (en) | 2008-09-04 | 2013-04-24 | Early Bird Drinks B.V. | Hangover relief by compositions comprising oral rehydration solution |
EP2172115A1 (en) | 2008-10-03 | 2010-04-07 | Ivan Biffi | Composition for use in the reduction of blood alcohol content |
EP2223817A2 (en) | 2009-02-27 | 2010-09-01 | Magna Car Top Systems GmbH | Locking device for a cabriolet roof |
WO2012058589A1 (en) | 2010-10-28 | 2012-05-03 | Jonathan Burg | Compositions and methods to reduce hangover and reduce blood alcohol levels after alcohol consumption |
WO2012091251A1 (en) * | 2010-12-27 | 2012-07-05 | 순천대학교 산학협력단 | Drink composition for hangover relief, containing cucumber vinegar |
Non-Patent Citations (1)
Title |
---|
DATABASE EPODOC [online] EUROPEAN PATENT OFFICE, THE HAGUE, NL; 5 July 2012 (2012-07-05), "Drink composition for hangover relief, containing cucumber vinegar", XP002713345, Database accession no. KR-2011007213-W * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016036254A1 (en) * | 2014-09-03 | 2016-03-10 | Kystvågen Slip & Mek As | Crawler configured for submarine use |
GB2544024A (en) * | 2014-09-03 | 2017-05-03 | Kystvágen Slip & Mek As | Crawler configured for submarine use |
GB2544024B (en) * | 2014-09-03 | 2020-04-08 | Kystvagen Slip & Mek As | Crawler configured for submarine use |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102218096B (en) | Composition for relieving the effects of alcohol and preventing hangover and disintoxicating drink having the composition | |
CN101889679B (en) | Composition with disintoxicating and liver-protecting effects and application thereof in food and health-care food | |
CN101460159B (en) | Fatigue-reducing agent | |
CN105942533B (en) | A kind of functional beverage and functional beverage effervescent tablet | |
CA2434388C (en) | Activated charcoal based composition and method for reducing hangover symptoms associated with the consumption of alcohol containing beverages | |
US10945979B1 (en) | Amino acid compositions to promote endothelial health | |
US20190314298A1 (en) | Compositions for preventing and relieving hangover & liver damage which occur due to alcohol consumption | |
RU2757379C2 (en) | Composition for the treatment of veisalgia | |
JP4119629B2 (en) | Antihypertensive agent | |
JP2008120754A (en) | Antifatigue agent | |
CN101861959A (en) | Pearl nutritional vinegar oral liquid | |
WO2015008101A1 (en) | Composition of a drink for enhanced reduction of blood alcohol level | |
JP2008088101A (en) | Antifatigue agent | |
JP2007008866A (en) | Hypotensive agent composition | |
KR20130119424A (en) | Ingredients derived from sphaeranthus indicus | |
ES2618930T5 (en) | Composition comprising diamine oxidase for the prevention of hangover symptoms | |
US20160038405A1 (en) | Effervescent multi-vitamin/mineral additive for coffee and tea | |
CN105708966A (en) | Wintercherry effervescent tablets with blood glucose reduction function and preparation method of wintercherry effervescent tablets | |
JP5946240B2 (en) | Method for enhancing physiological action of caffeine | |
US20230270711A1 (en) | Improved Anti-Hangover Composition, Its Preparation and Uses | |
KR20130065117A (en) | Composition comprising water extracts from tremella foliacea fr. for treating or preventing obesity | |
US7390513B2 (en) | Food supplement formulation | |
US20190320688A1 (en) | Compositions for preventing and relieving hangover & liver damage which occur due to alcohol consumption | |
JP2006328079A (en) | Composition stimulating specific metalloenzyme | |
Berbari et al. | Secondary hypertension: infrequently considered aspects—illicit/recreational substances, herbal remedies, and drug-associated hypertension |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 13752921 Country of ref document: EP Kind code of ref document: A1 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 13752921 Country of ref document: EP Kind code of ref document: A1 |