WO2014209908A4 - Substance concentration measurement using a cooling device with endothermic reaction - Google Patents

Substance concentration measurement using a cooling device with endothermic reaction Download PDF

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Publication number
WO2014209908A4
WO2014209908A4 PCT/US2014/043716 US2014043716W WO2014209908A4 WO 2014209908 A4 WO2014209908 A4 WO 2014209908A4 US 2014043716 W US2014043716 W US 2014043716W WO 2014209908 A4 WO2014209908 A4 WO 2014209908A4
Authority
WO
WIPO (PCT)
Prior art keywords
temperature
cooling device
assay surface
lid
subject
Prior art date
Application number
PCT/US2014/043716
Other languages
French (fr)
Other versions
WO2014209908A9 (en
WO2014209908A3 (en
WO2014209908A2 (en
Inventor
Yonatan Gerlitz
Meir Shitrit
Original Assignee
Glucovista Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glucovista Inc. filed Critical Glucovista Inc.
Priority to JP2016521891A priority Critical patent/JP6594302B2/en
Priority to EP14739644.4A priority patent/EP3013229A2/en
Priority to CN201480035578.9A priority patent/CN105338899B/en
Publication of WO2014209908A2 publication Critical patent/WO2014209908A2/en
Publication of WO2014209908A3 publication Critical patent/WO2014209908A3/en
Publication of WO2014209908A4 publication Critical patent/WO2014209908A4/en
Publication of WO2014209908A9 publication Critical patent/WO2014209908A9/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/10—Cooling bags, e.g. ice-bags
    • A61F7/106—Cooling bags, e.g. ice-bags self-cooling, e.g. using a chemical reaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3205—Separate rigid or semi-rigid containers joined to each other at their external surfaces
    • B65D81/3211—Separate rigid or semi-rigid containers joined to each other at their external surfaces coaxially and provided with means facilitating admixture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0095—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator
    • A61F2007/0096—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator with a thermometer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0268—Compresses or poultices for effecting heating or cooling having a plurality of compartments being filled with a heat carrier
    • A61F2007/0276—Compresses or poultices for effecting heating or cooling having a plurality of compartments being filled with a heat carrier with separate compartments connectable by rupturing a wall or membrane

Abstract

A measurement apparatus includes a cooling device including two separated, different substances exhibiting an endothermic reaction when combined to decrease a temperature of the cooling device and a contacting mechanism to contact an assay surface with the cooling device. The apparatus includes a temperature measurement device to measure a temperature of the assay surface and an infrared radiation detector to measure infrared radiation emitted or absorbed. A data processor is configured to determine a concentration of a substance in the subject's body using the measured temperature and the infrared radiation. A measurement method includes using the cooling device and decreasing a temperature of the assay surface to a lower temperature, then measuring a temperature of the assay surface during an increase of the temperature. An infrared radiation detector measures infrared radiation emitted from or absorbed by the assay surface during the temperature increase from the lower temperature.

Claims

AMENDED CLAIMS received by the International Bureau on 5 March 2015 (05.03.2015) What is claimed is:
1 . A measurement apparatus comprising:
a cooling device including two separated, different substances exhibiting an endothermic reaction when combined to decrease a temperature of the cooling device;
a combining mechanism of the cooling device configured to combine the two different substances;
a contacting mechanism configured to contact an assay surface of a subject's body with the cooling device and thereby to decrease a temperature of the assay surface of a subject's body to a lower temperature;
a temperature measurement device configured to measure a temperature of the assay surface of a subject's body during an increase of the temperature from the lower temperature;
an infrared radiation detector configured to measure infrared radiation emitted from or absorbed by the assay surface of a subject's body during the temperature increase; and
a data processor configured to determine a concentration of a substance in the subject's body using the measured temperature of the assay surface and the measured infrared radiation.
2. The apparatus of claim 1 wherein the processor is configured to determine a rate of temperature change of the assay surface and the processor is configured to determine the concentration using the rate of temperature change.
3. The apparatus of claim 1 wherein the cooling device comprises: a rigid shell including a base, a lid that attaches to the base, and an opening through the lid;
a flexible bag having a size and shape configured to fit within the shell with the lid closed and expose the bag above the opening through the lid, the bag containing a first of the two different substances;
a pouch within the flexible bag containing a second of the two different substances, the pouch being configured to release the second substance into the first substance upon opening the pouch.
4. The apparatus of claim 1 wherein the first substance is selected from among ammonium nitrate, calcium ammonium nitrate, urea, and combinations thereof.
5. The apparatus of claim 3 further comprising a mounting edge on opposing sides of the rigid shell, the mounting edge being configured to mount the cooling device to the measurement apparatus in a position.
6. The apparatus of claim 5 wherein the mounting edge comprises a circumferential flange of the lid and a circumferential flange of the base, the two flanges coinciding with one another with the lid closed.
19
7. A measurement method comprising:
using a cooling device including two separated, different substances exhibiting an endothermic reaction when combined;
using a combining mechanism of the cooling device, combining the two different substances;
using the combined substances, decreasing a temperature of the cooling device;
using a contacting mechanism, contacting an assay surface of a subject's body with the cooling device and thereby decreasing a temperature of the assay surface of the subject's body to a lower temperature;
after decreasing the temperature of the assay surface using the cooling device, using a temperature measurement device and measuring a temperature of the assay surface of the subject's body during an increase of the temperature of the assay surface from the lower temperature;
using an infrared radiation detector and measuring infrared radiation emitted from or absorbed by the assay surface during the temperature increase from the lower temperature; and
using a data processor, determining a concentration of a substance in the subject's body using the measured temperature of the assay surface and the measured infrared radiation.
20
8. A cooling device comprising;
a rigid shell including a base, a lid that attaches to the base, and an opening through the lid;
a flexible bag having a size and shape configured to fit within the shell with the lid closed and expose the bag above the opening through the lid, the bag containing a first of the two different substances;
a pouch within the flexible bag containing a second of the two different substances, the pouch being configured to release the second substance into the first substance upon opening the pouch; and
a mounting edge on opposing sides of the rigid shell, the mounting edge being configured to mount the cooling device to a measurement apparatus in a position
9. The cooling device of claim 8 wherein the mounting edge comprises a circumferential flange of the lid and a circumferential flange of the base, the two flanges coinciding with one another with the lid closed.
21
PCT/US2014/043716 2013-06-23 2014-06-23 Measurement apparatuses and methods using a combined substance cooling device WO2014209908A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2016521891A JP6594302B2 (en) 2013-06-23 2014-06-23 Concentration measurement of substances using a cooling device using endothermic reaction
EP14739644.4A EP3013229A2 (en) 2013-06-23 2014-06-23 Substance concentration measurement using a cooling device with endothermic reaction
CN201480035578.9A CN105338899B (en) 2013-06-23 2014-06-23 The concentration measurements carried out using the cooling device with the endothermic reaction

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361838329P 2013-06-23 2013-06-23
US61/838,329 2013-06-23

Publications (4)

Publication Number Publication Date
WO2014209908A2 WO2014209908A2 (en) 2014-12-31
WO2014209908A3 WO2014209908A3 (en) 2015-02-26
WO2014209908A4 true WO2014209908A4 (en) 2015-04-23
WO2014209908A9 WO2014209908A9 (en) 2015-05-14

Family

ID=51205611

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/043716 WO2014209908A2 (en) 2013-06-23 2014-06-23 Measurement apparatuses and methods using a combined substance cooling device

Country Status (4)

Country Link
EP (1) EP3013229A2 (en)
JP (1) JP6594302B2 (en)
CN (1) CN105338899B (en)
WO (1) WO2014209908A2 (en)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55152778A (en) * 1979-05-18 1980-11-28 Masao Ozawa Cooling bag
JPH0298358A (en) * 1988-10-05 1990-04-10 Nippon Chiyougoku Onkiyuu Kk Medical coolant and medical cooling device using same
US20060036304A1 (en) * 2001-11-01 2006-02-16 Peter Cordani Thermal garment system and method of using the same
US20090069741A1 (en) * 2004-04-09 2009-03-12 Palomar Medical Technologies, Inc. Methods And Devices For Fractional Ablation Of Tissue For Substance Delivery
US8165668B2 (en) * 2007-12-05 2012-04-24 The Invention Science Fund I, Llc Method for magnetic modulation of neural conduction
US8170660B2 (en) * 2007-12-05 2012-05-01 The Invention Science Fund I, Llc System for thermal modulation of neural activity
US9251012B2 (en) * 2008-01-18 2016-02-02 Tivo Inc. Distributed backup and retrieval system
US8401604B2 (en) * 2008-04-11 2013-03-19 Glucovista, Llc Apparatus and methods for non-invasive measurement of a substance within a body
US20110004080A1 (en) * 2008-04-11 2011-01-06 Glucovista, Llc Method for non-invasive analysis of a substance concentration within a body
US8611975B2 (en) * 2009-10-28 2013-12-17 Gluco Vista, Inc. Apparatus and method for non-invasive measurement of a substance within a body
MY159401A (en) * 2010-05-19 2016-12-30 Kismet Design Pty Ltd Heat transfer apparatus and container

Also Published As

Publication number Publication date
JP2016523148A (en) 2016-08-08
WO2014209908A9 (en) 2015-05-14
CN105338899A (en) 2016-02-17
CN105338899B (en) 2019-08-20
EP3013229A2 (en) 2016-05-04
JP6594302B2 (en) 2019-10-23
WO2014209908A3 (en) 2015-02-26
WO2014209908A2 (en) 2014-12-31

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