WO2014193251A1 - Preparation for maintenance of oral cavity hygiene and prevention of plaque formation - Google Patents
Preparation for maintenance of oral cavity hygiene and prevention of plaque formation Download PDFInfo
- Publication number
- WO2014193251A1 WO2014193251A1 PCT/PL2013/050011 PL2013050011W WO2014193251A1 WO 2014193251 A1 WO2014193251 A1 WO 2014193251A1 PL 2013050011 W PL2013050011 W PL 2013050011W WO 2014193251 A1 WO2014193251 A1 WO 2014193251A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- preparation
- content
- distinctive feature
- mustard
- sodium
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
Definitions
- the subject of the invention is compound preparation for maintenance of the oral cavity hygiene and prevention of plaque formation which contains ingredients obtained from seeds of Synapsis alba (white mustard).
- Dental caries and periodontal diseases are associated with activity of bacteria in the oral cavity. These bacteria are an element of dental plaque which in a process of mineralization is transformed in supragingival and sub-gingival calculus. Improper hygiene of the oral cavity, diet and susceptibility of dental hard tissues lead to dental caries. At the same time, microbes which are present in dental plaque are the most important etiological agents of periodontitis. Insufficient hygiene and tissue susceptibility may lead to gingivitis and periodontitis. When untreated, gingivitis may lead to formation of pathological pockets, destruction of connective tissue adhesion as well as to lysis of the alveolar ridge and in consequence to loss of teeth.
- the preparations for oral cavity hygiene may include antibacterial agents. They inhibit development of bacteria in the oral cavity.
- antibacterial agents They inhibit development of bacteria in the oral cavity.
- use of enzymes which prevent deposition of dental plaque by reduction of bacterial adhesion to teeth surface has been described in US 2 527 686, US3 991 177, US3 194 738, US4 082 841, US4 115 546, US4 140 759, i US5 849 271patent descriptions. It is also beneficial to add plant extracts of antibacterial and/or antifungal properties. Toothpastes with chamomile, salvia, mint or clove extracts are also commonly known.
- WO0103662A1 describes a preparation for oral cavity hygiene with clove extract which prevents gum diseases and bad breath (halitosis).
- US20090054520A1 reveals composition of the product for dental care which includes chamomile extract.
- the goal of the invention has been development of the preparation in a form of tooth paste based on active substance of herbal origin which shows definite antibacterial and antifungal effect on the oral cavity, in particular tooth and gums.
- the product for maintenance of oral cavity hygiene and prevention of plaque deposition contains from 0.1 to 0.8% of sinablin and its derivatives in a beneficial form of mustard oil, 0.1 to 0.8% or from 0.1 to 8% of mustard extract and/or 0.1 to 0.8% of mustard marc.
- the composition contains from 10.0 to 50.0% of hydrated sodium biphosphate and/or from 10.0 to 50.0% of hydrated bicalcium phosphate and/or 10.04 - 40.0% of hydrated silica and/or 0.1 to 8.0% of colloidal silica and/or 5.0 to 50% of glycerin and water to 100%.
- the product contains from 1.0 to 5.0% of carboxymethyl cellulose and/or from 0.2 to 6.0% of sodium lauryl sulfate which is beneficial.
- Composition of the preparation also includes from 30.0 to 70.0% of sorbitol and/or 0.2 to 0.5 of sodium saccharine and/or 0.5- 2.0% of titanium bicarbonate.
- the product contains from 0.05 to 0.8% preservative paraben such as sodium methylparaben and/or from 0.5 to 0.8% of sodium benzoate. Additionally, the composition contains from 0.5% to 3.0% of known aromatic substances. Sinablin and its derivatives are obtained in extraction of powdered mustard seed with ethanol, extraction of mustard oil which is performed with commonly applied methods, addition of white mustard marc and powdered whole seeds.
- the toothpaste has a delicate, herbal flavor and shows antibacterial and antifungal properties.
- the preparation in a form of toothpaste contains 1% of mustard extract, 37% of hydrated sodium biphosphate, 3% of colloidal silica, 26% of glycerine, 1.2% of carboxym ethyl cellulose, 1.1% of sodium lauryl sulfate, 0.1% of sodium methylparaben, 0.2% of sodium benzoate and water to 100%
- the preparation in a form of toothpaste contains 1.0% of mustard marc, 36% of hydrated sodium biphosphate, 3.0% of colloidal silica, 27% of glycerine, 1.2% of carboxymethylo cellulose, 1.2% of sodium lauryl sulfate, 0.1% of sodium methylparaben, 0.2% of sodium benzoate and water to 100%
- the preparation in a form of toothpaste contains 1.0% of mustard oil, 30% of hydrated silica, 25% of glycerine, 1.2% of carboxymethylo cellulose, 2% of sodium lauryl sulfate, 30% of sorbitol, 2% of cellulose gum, 1% of titanium bicarbonate, 0.2% of sodium saccharine and water to 100%.
Abstract
The preparation in a form of toothpaste contains hydratedsodium biphosphate, silica, glycerine and water as well as from 0.1 to 0.8% of sinablinand or its derivatives, from 10.0 to 50.0% of hydrated sodium bisphosphate and/or from 10.0 to 50% of hydrated dicalcium phosphate and/or from 10.0 to 40.0% of hydrated silica and/or 0.1 to 8.0 % of colloidal silica and/or from 5.0 to 50% of glycerineand/or from 30.0 to 70% of sorbitol and water to 100%. Sinablin and /or its derivatives are present in a form of mustard oil, from 0.1 to 8.0% and/or from 0.1 to 8% of alcohol mustard extract and/or from 0.1 to 8.0% of mustard marc.
Description
Preparation for maintenance of oral cavity hygiene and prevention of plaque formation
The subject of the invention is compound preparation for maintenance of the oral cavity hygiene and prevention of plaque formation which contains ingredients obtained from seeds of Synapsis alba (white mustard).
Dental caries and periodontal diseases are associated with activity of bacteria in the oral cavity. These bacteria are an element of dental plaque which in a process of mineralization is transformed in supragingival and sub-gingival calculus. Improper hygiene of the oral cavity, diet and susceptibility of dental hard tissues lead to dental caries. At the same time, microbes which are present in dental plaque are the most important etiological agents of periodontitis. Insufficient hygiene and tissue susceptibility may lead to gingivitis and periodontitis. When untreated, gingivitis may lead to formation of pathological pockets, destruction of connective tissue adhesion as well as to lysis of the alveolar ridge and in consequence to loss of teeth.
It is commonly known that the preparations for oral cavity hygiene may include antibacterial agents. They inhibit development of bacteria in the oral cavity. For example, use of enzymes which prevent deposition of dental plaque by reduction of bacterial adhesion to teeth surface has been described in US 2 527 686, US3 991 177, US3 194 738, US4 082 841, US4 115 546, US4 140 759, i US5 849 271patent descriptions.
It is also beneficial to add plant extracts of antibacterial and/or antifungal properties. Toothpastes with chamomile, salvia, mint or clove extracts are also commonly known.
For example WO0103662A1 describes a preparation for oral cavity hygiene with clove extract which prevents gum diseases and bad breath (halitosis). US20090054520A1 reveals composition of the product for dental care which includes chamomile extract.
The goal of the invention has been development of the preparation in a form of tooth paste based on active substance of herbal origin which shows definite antibacterial and antifungal effect on the oral cavity, in particular tooth and gums.
The product for maintenance of oral cavity hygiene and prevention of plaque deposition, according to the formula, contains from 0.1 to 0.8% of sinablin and its derivatives in a beneficial form of mustard oil, 0.1 to 0.8% or from 0.1 to 8% of mustard extract and/or 0.1 to 0.8% of mustard marc. Besides, the composition contains from 10.0 to 50.0% of hydrated sodium biphosphate and/or from 10.0 to 50.0% of hydrated bicalcium phosphate and/or 10.04 - 40.0% of hydrated silica and/or 0.1 to 8.0% of colloidal silica and/or 5.0 to 50% of glycerin and water to 100%. The product contains from 1.0 to 5.0% of carboxymethyl cellulose and/or from 0.2 to 6.0% of sodium lauryl sulfate which is beneficial. Composition of the preparation also includes from 30.0 to 70.0% of sorbitol and/or 0.2 to 0.5 of sodium saccharine and/or 0.5- 2.0% of titanium bicarbonate. The product contains from 0.05 to 0.8% preservative paraben such as sodium methylparaben and/or from 0.5 to 0.8% of sodium benzoate. Additionally, the composition contains from 0.5% to 3.0% of known aromatic substances.
Sinablin and its derivatives are obtained in extraction of powdered mustard seed with ethanol, extraction of mustard oil which is performed with commonly applied methods, addition of white mustard marc and powdered whole seeds.
It is also acceptable to use oil from white mustard which is obtained as a waste in mustard production (from marcs).
According to description of the patent, the toothpaste has a delicate, herbal flavor and shows antibacterial and antifungal properties.
Below, we provide examples of preparation
Example I
The preparation in a form of toothpaste contains 1% of mustard extract, 37% of hydrated sodium biphosphate, 3% of colloidal silica, 26% of glycerine, 1.2% of carboxym ethyl cellulose, 1.1% of sodium lauryl sulfate, 0.1% of sodium methylparaben, 0.2% of sodium benzoate and water to 100%
Example II
The preparation in a form of toothpaste contains 1.0% of mustard marc, 36% of hydrated sodium biphosphate, 3.0% of colloidal silica, 27% of glycerine, 1.2% of carboxymethylo cellulose, 1.2% of sodium lauryl sulfate, 0.1% of sodium methylparaben, 0.2% of sodium benzoate and water to 100%
Example III
The preparation in a form of toothpaste contains 1.0% of mustard oil, 30% of hydrated silica, 25% of glycerine, 1.2% of carboxymethylo cellulose, 2% of sodium lauryl sulfate, 30% of sorbitol, 2% of cellulose gum, 1% of titanium bicarbonate, 0.2% of sodium saccharine and water to 100%.
Claims
1. Preparation in a form of toothpaste which contains sodium biphosphate, silica, glycerine and water. What distinguishes the product is content of 0.1 to 0.8% of sinablin and/or its derivatives, from 10.0 to 50% of hydrated sodium biphospate and/or from 10.0 to 50% of hydrated bicalcium phosphate and/or from 10,0 to 40,0% of hydrated silica and/or from 0,1 to 8,0 % of colloidal silica and/or from 5,0 to 50,0% of glycerine and/or from 30.0 to 70% of sorbitol and water to 100%.
2. According to claim 1, the distinctive feature of the preparation is content of sinablin and/or its derivatives in a form from of mustard oil, from 0.1 to 8% of alcohol mustard extract 8% and/or from 0.1 to 8% of alcohol mustard marc.
3. According to claim 1 or 2, the distinctive feature of the preparation is content of 1.0 to 5.0% of carboxym ethyl cellulose.
4. According to claim 1 or 2 or 3 the distinctive feature of the preparation is content lauryl sodium sulfate, from 0.2 to 6.0%.
5. According to claim 1 or 2 or 3 or 4 the distinctive feature of the preparation is content from 0.2 to 0.5 of sodium saccharine.
6. According to claim 1 or 2 or 3 or 4 or 5 the distinctive feature of preparation is content from 0,5 to 2,0% of titanium bicarbonate.
7. According to any of 1 - 6 claims, the distinctive feature of the preparation is content of the preservatives in a form of parabens such as sodium methylparaben, from 0.05 to 0.8%.
8. According to any of 1 - 7 claims, the distinctive feature of the preparation is content of the preservatives in a form of sodium benzoate, from 0.5 to 0.8%.
9. According to any of 1 - 8 claims, the distinctive feature of the preparation is content of aromatic substances, from 0.5 to 3.0%.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PLP.404147 | 2013-05-30 | ||
PL404147A PL234907B1 (en) | 2013-05-30 | 2013-05-30 | Preparation for oral hygiene and preventing a plaque |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2014193251A1 true WO2014193251A1 (en) | 2014-12-04 |
Family
ID=48875116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/PL2013/050011 WO2014193251A1 (en) | 2013-05-30 | 2013-06-10 | Preparation for maintenance of oral cavity hygiene and prevention of plaque formation |
Country Status (2)
Country | Link |
---|---|
PL (1) | PL234907B1 (en) |
WO (1) | WO2014193251A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109512739A (en) * | 2018-12-14 | 2019-03-26 | 西藏班公湖藏药材开发有限责任公司 | Tibetan medicine adult's formulation of tooth-paste |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2527686A (en) | 1945-12-26 | 1950-10-31 | Max H Sandberg | Mouthwash |
US3194738A (en) | 1962-03-14 | 1965-07-13 | American Chicle Co | Chewing gums and dentifrices containing enzymes |
US3991177A (en) | 1973-11-27 | 1976-11-09 | Colgate-Palmolive Company | Oral compositions containing dextranase |
US4082841A (en) | 1975-10-10 | 1978-04-04 | Lever Brothers Company | Dentifrice |
US4115546A (en) | 1975-03-12 | 1978-09-19 | Colgate Palmolive Company | Oral compositions containing dextranase |
US4140759A (en) | 1977-07-13 | 1979-02-20 | Helena Rubinstein, Inc. | Protein shampoo |
US4165368A (en) * | 1977-07-01 | 1979-08-21 | Colgate Palmolive Company | Dental prophylactic paste |
WO1998053698A1 (en) * | 1997-05-27 | 1998-12-03 | Sembiosys Genetics Inc. | Uses of oil bodies |
US5849271A (en) | 1995-06-07 | 1998-12-15 | The Procter & Gamble Company | Oral compositions |
WO2001003662A1 (en) | 1999-07-12 | 2001-01-18 | Vita-Myr International Corp. | Dentifrice |
US20090054520A1 (en) | 2007-08-20 | 2009-02-26 | Symrise Gmbh & Co. Kg | Oxalic acid derivatives and use thereof as physiological cooling active ingredients |
US20120171128A1 (en) * | 2010-12-30 | 2012-07-05 | Jr Chem, Llc | Dental cleaning composition |
-
2013
- 2013-05-30 PL PL404147A patent/PL234907B1/en unknown
- 2013-06-10 WO PCT/PL2013/050011 patent/WO2014193251A1/en active Application Filing
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2527686A (en) | 1945-12-26 | 1950-10-31 | Max H Sandberg | Mouthwash |
US3194738A (en) | 1962-03-14 | 1965-07-13 | American Chicle Co | Chewing gums and dentifrices containing enzymes |
US3991177A (en) | 1973-11-27 | 1976-11-09 | Colgate-Palmolive Company | Oral compositions containing dextranase |
US4115546A (en) | 1975-03-12 | 1978-09-19 | Colgate Palmolive Company | Oral compositions containing dextranase |
US4082841A (en) | 1975-10-10 | 1978-04-04 | Lever Brothers Company | Dentifrice |
US4165368A (en) * | 1977-07-01 | 1979-08-21 | Colgate Palmolive Company | Dental prophylactic paste |
US4140759A (en) | 1977-07-13 | 1979-02-20 | Helena Rubinstein, Inc. | Protein shampoo |
US5849271A (en) | 1995-06-07 | 1998-12-15 | The Procter & Gamble Company | Oral compositions |
WO1998053698A1 (en) * | 1997-05-27 | 1998-12-03 | Sembiosys Genetics Inc. | Uses of oil bodies |
WO2001003662A1 (en) | 1999-07-12 | 2001-01-18 | Vita-Myr International Corp. | Dentifrice |
US20090054520A1 (en) | 2007-08-20 | 2009-02-26 | Symrise Gmbh & Co. Kg | Oxalic acid derivatives and use thereof as physiological cooling active ingredients |
US20120171128A1 (en) * | 2010-12-30 | 2012-07-05 | Jr Chem, Llc | Dental cleaning composition |
Non-Patent Citations (1)
Title |
---|
ATHULA EKANAYAKE ET AL: "Development of white mustard (L.) essential oil, a food preservative", FOOD CHEMISTRY, ELSEVIER LTD, NL, vol. 133, no. 3, 25 January 2012 (2012-01-25), pages 767 - 774, XP028468303, ISSN: 0308-8146, [retrieved on 20120204], DOI: 10.1016/J.FOODCHEM.2012.01.090 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109512739A (en) * | 2018-12-14 | 2019-03-26 | 西藏班公湖藏药材开发有限责任公司 | Tibetan medicine adult's formulation of tooth-paste |
Also Published As
Publication number | Publication date |
---|---|
PL404147A1 (en) | 2014-12-08 |
PL234907B1 (en) | 2020-05-18 |
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