WO2014120678A3 - Tube and float systems and methods of using the same - Google Patents

Tube and float systems and methods of using the same Download PDF

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Publication number
WO2014120678A3
WO2014120678A3 PCT/US2014/013434 US2014013434W WO2014120678A3 WO 2014120678 A3 WO2014120678 A3 WO 2014120678A3 US 2014013434 W US2014013434 W US 2014013434W WO 2014120678 A3 WO2014120678 A3 WO 2014120678A3
Authority
WO
WIPO (PCT)
Prior art keywords
tube
float
expandable
methods
portions
Prior art date
Application number
PCT/US2014/013434
Other languages
French (fr)
Other versions
WO2014120678A2 (en
Inventor
Daniel CAMPTON
Joshua Nordberg
Evan CASTIGLIA
Original Assignee
Rarecyte, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rarecyte, Inc. filed Critical Rarecyte, Inc.
Priority to EP14746363.2A priority Critical patent/EP2951578A4/en
Priority to CN201480017865.7A priority patent/CN105074459A/en
Publication of WO2014120678A2 publication Critical patent/WO2014120678A2/en
Publication of WO2014120678A3 publication Critical patent/WO2014120678A3/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021Test tubes specially adapted for centrifugation purposes
    • B01L3/50215Test tubes specially adapted for centrifugation purposes using a float to separate phases

Abstract

This disclosure is directed to systems and methods for analyzing target materials of a suspension include a tube and a float. The float may include expandable portions. The system traps a target analyte between the expandable float and the tube and/or to create a seal between the expandable float and the tube to inhibit fluid from flowing past the expandable float in the tube. The expandable portions may radially expand when exposed to an expanding fluid, such that the expanding fluid is not a naturally-occurring constituent of the suspension; or, the expandable portions may radially expand when a force is exerted upon the expandable portion. A tube may include expandable portions that expand towards the float.
PCT/US2014/013434 2013-02-01 2014-01-28 Tube and float systems and methods of using the same WO2014120678A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP14746363.2A EP2951578A4 (en) 2013-02-01 2014-01-28 Tube and float systems and methods of using the same
CN201480017865.7A CN105074459A (en) 2013-02-01 2014-01-28 Tube and float systems and methods of using the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361759495P 2013-02-01 2013-02-01
US61/759,495 2013-02-01

Publications (2)

Publication Number Publication Date
WO2014120678A2 WO2014120678A2 (en) 2014-08-07
WO2014120678A3 true WO2014120678A3 (en) 2014-12-31

Family

ID=51263107

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/013434 WO2014120678A2 (en) 2013-02-01 2014-01-28 Tube and float systems and methods of using the same

Country Status (3)

Country Link
EP (1) EP2951578A4 (en)
CN (1) CN105074459A (en)
WO (1) WO2014120678A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016025527A1 (en) * 2014-08-12 2016-02-18 Rarecyte, Inc. Tube and float systems and methods of using the same
DE102017108935B4 (en) 2017-04-26 2018-12-06 Sarstedt Aktiengesellschaft & Co.Kg Separator and tubular container with the separator
DE102017108933B4 (en) 2017-04-26 2018-12-06 Sarstedt Aktiengesellschaft & Co.Kg separating body
DE102017108937B4 (en) 2017-04-26 2018-12-06 Sarstedt Aktiengesellschaft & Co.Kg separating body

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5393674A (en) * 1990-12-31 1995-02-28 Levine Robert A Constitutent layer harvesting from a centrifuged sample in a tube
US5560830A (en) * 1994-12-13 1996-10-01 Coleman; Charles M. Separator float and tubular body for blood collection and separation and method of use thereof
US20070092971A1 (en) * 2002-10-03 2007-04-26 Battelle Memorial Institute Buffy coat separator float system and method
US20070190584A1 (en) * 2001-01-08 2007-08-16 Becton, Dickinson And Company Method of separating cells from a sample
US20120308447A1 (en) * 2011-05-31 2012-12-06 Timothy Alan Abrahamson Tube and float systems for density-based fluid separation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3919085A (en) * 1974-02-27 1975-11-11 Becton Dickinson Co Plasma separator assembly
US7673758B2 (en) * 2005-08-10 2010-03-09 The Regents Of The University Of California Collection tubes apparatus, systems, and methods

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5393674A (en) * 1990-12-31 1995-02-28 Levine Robert A Constitutent layer harvesting from a centrifuged sample in a tube
US5560830A (en) * 1994-12-13 1996-10-01 Coleman; Charles M. Separator float and tubular body for blood collection and separation and method of use thereof
US20070190584A1 (en) * 2001-01-08 2007-08-16 Becton, Dickinson And Company Method of separating cells from a sample
US20070092971A1 (en) * 2002-10-03 2007-04-26 Battelle Memorial Institute Buffy coat separator float system and method
US20120308447A1 (en) * 2011-05-31 2012-12-06 Timothy Alan Abrahamson Tube and float systems for density-based fluid separation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2951578A4 *

Also Published As

Publication number Publication date
EP2951578A4 (en) 2016-09-14
EP2951578A2 (en) 2015-12-09
CN105074459A (en) 2015-11-18
WO2014120678A2 (en) 2014-08-07

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