WO2014031523A3 - Microfluidic device with reduced channel height - Google Patents

Microfluidic device with reduced channel height Download PDF

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Publication number
WO2014031523A3
WO2014031523A3 PCT/US2013/055541 US2013055541W WO2014031523A3 WO 2014031523 A3 WO2014031523 A3 WO 2014031523A3 US 2013055541 W US2013055541 W US 2013055541W WO 2014031523 A3 WO2014031523 A3 WO 2014031523A3
Authority
WO
WIPO (PCT)
Prior art keywords
microfluidic device
channel height
reduced channel
microfluidic devices
reduced
Prior art date
Application number
PCT/US2013/055541
Other languages
French (fr)
Other versions
WO2014031523A2 (en
Inventor
James L. Mcgrath
Dean G. JOHNSON
Original Assignee
University Of Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Rochester filed Critical University Of Rochester
Publication of WO2014031523A2 publication Critical patent/WO2014031523A2/en
Publication of WO2014031523A3 publication Critical patent/WO2014031523A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B3/00—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar form; Layered products having particular features of form
    • B32B3/26—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar form; Layered products having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layer; characterised by a layer with cavities or internal voids ; characterised by an apertured layer
    • B32B3/30—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar form; Layered products having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layer; characterised by a layer with cavities or internal voids ; characterised by an apertured layer characterised by a layer formed with recesses or projections, e.g. hollows, grooves, protuberances, ribs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B38/00—Ancillary operations in connection with laminating processes
    • B32B38/06—Embossing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/50—Properties of the layers or laminate having particular mechanical properties
    • B32B2307/51—Elastic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/704—Crystalline
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/728—Hydrophilic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/73—Hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2309/00—Parameters for the laminating or treatment process; Apparatus details
    • B32B2309/08—Dimensions, e.g. volume
    • B32B2309/10—Dimensions, e.g. volume linear, e.g. length, distance, width
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2310/00—Treatment by energy or chemical effects
    • B32B2310/04—Treatment by energy or chemical effects using liquids, gas or steam
    • B32B2310/0445—Treatment by energy or chemical effects using liquids, gas or steam using gas or flames
    • B32B2310/0463—Treatment by energy or chemical effects using liquids, gas or steam using gas or flames other than air
    • B32B2310/0481—Ozone
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2319/00—Synthetic rubber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B38/00—Ancillary operations in connection with laminating processes
    • B32B38/0008—Electrical discharge treatment, e.g. corona, plasma treatment; wave energy or particle radiation

Abstract

Methods for preparing low volume microfluidic devices are disclosed along with the resulting microfluidic devices, the use of these microfluidic devices, and kits for forming the microfluidic devices of the present invention.
PCT/US2013/055541 2012-08-19 2013-08-19 Method for preparing microfluidic device with reduced channel height WO2014031523A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261684796P 2012-08-19 2012-08-19
US61/684,796 2012-08-19

Publications (2)

Publication Number Publication Date
WO2014031523A2 WO2014031523A2 (en) 2014-02-27
WO2014031523A3 true WO2014031523A3 (en) 2014-05-08

Family

ID=50150470

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/055541 WO2014031523A2 (en) 2012-08-19 2013-08-19 Method for preparing microfluidic device with reduced channel height

Country Status (1)

Country Link
WO (1) WO2014031523A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170173578A1 (en) * 2014-03-14 2017-06-22 Board Of Regents, The University Of Texas System Microfluidic devices for the rapid detection of analytes
WO2016164738A1 (en) 2015-04-08 2016-10-13 Board Of Regents, The University Of Texas System Methods and systems for the detection of analytes
CN110577883B (en) * 2019-09-09 2022-09-23 武汉纺织大学 Cell sorting device based on micro-fluidic chip
CN113634296B (en) * 2021-10-19 2022-02-11 北京芯迈微生物技术有限公司 Micro-fluidic chip

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6375871B1 (en) * 1998-06-18 2002-04-23 3M Innovative Properties Company Methods of manufacturing microfluidic articles
US6610499B1 (en) * 2000-08-31 2003-08-26 The Regents Of The University Of California Capillary array and related methods
US7186352B2 (en) * 2002-04-24 2007-03-06 The Regents Of The University Of California Microfluidic systems with embedded materials and structures and method thereof
US7323143B2 (en) * 2000-05-25 2008-01-29 President And Fellows Of Harvard College Microfluidic systems including three-dimensionally arrayed channel networks
EP1341655B1 (en) * 2000-12-02 2008-10-15 Aquamarijn Holding BV Method of making a product with a micro or nano sized structure
US20090181200A1 (en) * 2007-09-19 2009-07-16 Borenstein Jeffrey T Microfluidic Structures for Biomedical Applications
US20100173310A1 (en) * 2007-06-11 2010-07-08 Luc Bousse Microchip large-volume pcr with integrated real-time ce detection
US20100233037A1 (en) * 2009-03-10 2010-09-16 Melin Jessica E Microfluidic valve with pressure gain
US20110086427A1 (en) * 2009-10-12 2011-04-14 Faris Ronald A Microfluidic device for cell culture
US20110085949A1 (en) * 2009-10-08 2011-04-14 Emmanuel Roy Microfluidic device, composition and method of forming
US20110201009A1 (en) * 2000-09-15 2011-08-18 California Institute Of Technology Microfabricated Crossflow Devices and Methods
US20120069488A1 (en) * 2008-12-16 2012-03-22 Massachusetts Institute Of Technology Method and apparatus for microcontact printing of mems
US20120107194A1 (en) * 2008-05-05 2012-05-03 Cornell University Channel and method of forming channels
US20120196376A1 (en) * 2009-08-21 2012-08-02 Cornell University Nanofilter devices using elastomeric micro to nanochannel interfaces and methods based thereon

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6375871B1 (en) * 1998-06-18 2002-04-23 3M Innovative Properties Company Methods of manufacturing microfluidic articles
US7323143B2 (en) * 2000-05-25 2008-01-29 President And Fellows Of Harvard College Microfluidic systems including three-dimensionally arrayed channel networks
US6610499B1 (en) * 2000-08-31 2003-08-26 The Regents Of The University Of California Capillary array and related methods
US20110201009A1 (en) * 2000-09-15 2011-08-18 California Institute Of Technology Microfabricated Crossflow Devices and Methods
EP1341655B1 (en) * 2000-12-02 2008-10-15 Aquamarijn Holding BV Method of making a product with a micro or nano sized structure
US7186352B2 (en) * 2002-04-24 2007-03-06 The Regents Of The University Of California Microfluidic systems with embedded materials and structures and method thereof
US20100173310A1 (en) * 2007-06-11 2010-07-08 Luc Bousse Microchip large-volume pcr with integrated real-time ce detection
US20090181200A1 (en) * 2007-09-19 2009-07-16 Borenstein Jeffrey T Microfluidic Structures for Biomedical Applications
US20120107194A1 (en) * 2008-05-05 2012-05-03 Cornell University Channel and method of forming channels
US20120069488A1 (en) * 2008-12-16 2012-03-22 Massachusetts Institute Of Technology Method and apparatus for microcontact printing of mems
US20100233037A1 (en) * 2009-03-10 2010-09-16 Melin Jessica E Microfluidic valve with pressure gain
US20120196376A1 (en) * 2009-08-21 2012-08-02 Cornell University Nanofilter devices using elastomeric micro to nanochannel interfaces and methods based thereon
US20110085949A1 (en) * 2009-10-08 2011-04-14 Emmanuel Roy Microfluidic device, composition and method of forming
US20110086427A1 (en) * 2009-10-12 2011-04-14 Faris Ronald A Microfluidic device for cell culture

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JOHNSON, DG ET AL.: "Micro-Molded Cannulae for Intracochlear Infusions in Small Rodents.", PROCEEDINGS OF THE 29TH ANNUAL INTERNATIONAL, CONFERÉNCE OFTHE IEEE EMBS, CITÉ INTERNATIONALE, 23 August 2007 (2007-08-23), LYON, FRANCE, pages 6616 - 6619 *
NOH, HS ET AL.: "Parylene micromolding, a rapid and low-cost fabrication method for parylene microchannel.", SENSORS AND ACTUATORS B CHEMICAL, vol. 102, 2004, pages 78 - 85 *

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