WO2013137500A1 - Wireless optical brain nerve stimulation system - Google Patents

Wireless optical brain nerve stimulation system Download PDF

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Publication number
WO2013137500A1
WO2013137500A1 PCT/KR2012/001870 KR2012001870W WO2013137500A1 WO 2013137500 A1 WO2013137500 A1 WO 2013137500A1 KR 2012001870 W KR2012001870 W KR 2012001870W WO 2013137500 A1 WO2013137500 A1 WO 2013137500A1
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WO
WIPO (PCT)
Prior art keywords
light
stimulation system
wireless
nerve stimulation
cranial nerve
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PCT/KR2012/001870
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French (fr)
Korean (ko)
Inventor
신희섭
최일환
김고근
조일주
윤의성
Original Assignee
한국과학기술연구원
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Application filed by 한국과학기술연구원 filed Critical 한국과학기술연구원
Priority to PCT/KR2012/001870 priority Critical patent/WO2013137500A1/en
Publication of WO2013137500A1 publication Critical patent/WO2013137500A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0622—Optical stimulation for exciting neural tissue

Definitions

  • Embodiments relate to a wireless cranial nerve stimulation system.
  • Electric or light brain stimulation technology is used to treat patients' diseases, and at the same time applied to animals other than humans to reveal the brain function.
  • the cranial nerve stimulation system that stimulates the cranial nerve using light expresses some channels and enzymes that are stimulated only by light of a specific wavelength in the nerve cell, and then illuminates the light of a specific wavelength without causing damage to the nerve cell. Only neurons of a kind are selectively stimulated / inhibited.
  • FIG. 1 is a view showing an embodiment of a conventional light stimulation system for brain stimulation.
  • a conventional optical fiber is inserted into an animal's brain and the optical fiber is connected to an external light source. Light emitted from the light source unit is transmitted to the cranial nerve through the optical fiber connected to the light source unit.
  • the photo-stimulated animal and the light source are physically connected through the optical fiber, so the optical fiber restricts the free movement of the photo-stimulated animal.
  • This may be a potential stressor for animals participating in behavioral experiments and may adversely affect the experimental results.
  • the behavior of an animal subjected to photostimulation may damage the optical fiber or the optical stimulation system may become unstable.
  • a wireless cranial nerve stimulation system that can ensure the free movement of the subject to be measured by implementing a cranial nerve stimulation system in a wireless manner.
  • the light source for irradiating light
  • a light receiving unit mounted on a living body to be measured to receive light emitted from the light source unit
  • an optical stimulator for stimulating the neural tissue by applying the light received from the light receiver to the neural tissue.
  • the wireless cranial nerve stimulation system since the measurement target living body and the light source are physically separated, it does not limit the movement of the measurement target living body.
  • FIG. 1 is a view showing an embodiment of a light stimulation system for brain stimulation used in the prior art.
  • FIG. 2 is a view schematically showing the configuration of a wireless cranial nerve stimulation system according to an embodiment.
  • FIG 3 is a schematic cross-sectional view of a light receiving unit according to an embodiment of the present invention.
  • FIG. 4 is a plan view of a light receiving unit according to an embodiment of the present invention.
  • FIG. 5 is a plan view of a light receiving unit according to another embodiment of the present invention.
  • Figure 6 is a schematic view showing the configuration of a wireless cranial nerve stimulation system according to another embodiment of the present invention.
  • Figure 7 is a schematic view showing the configuration of a wireless cranial nerve stimulation system according to another embodiment of the present invention.
  • FIG. 2 is a view schematically showing the configuration of a wireless cranial nerve stimulation system according to an embodiment.
  • the wireless cranial nerve stimulation system includes a light source unit 10, a light receiver 20, and a light stimulator 30.
  • the light source unit 10 irradiates light.
  • the light source unit 10 may be implemented as a light emitting diode (LED), a laser diode, or the like.
  • LED light emitting diode
  • laser diode or the like.
  • the light receiving unit 20 is mounted on the head of the living body (for example, the mouse) 1 to be measured to receive light emitted from the light source unit 10, and transmits the received light to the light stimulation unit 30.
  • the light receiving unit 20 includes at least one lens, and the lens is preferably made of any one of a convex lens, a concave lens, and a Fresnel lens.
  • the light receiving unit 20 may be formed in a tube shape, a part of which is inserted into the body of the living body 1.
  • this is merely exemplary, and the light receiving unit 20 applied to the present invention is not limited to having a specific shape or form.
  • the optical stimulation unit 30 is inserted into the brain of the living body (1) to be measured and connected to the cranial nerve tissue, and stimulates the cranial nerve tissue by applying the light received from the light receiving unit 20 to the cranial nerve tissue.
  • the optical stimulation unit 30 may be implemented with an optical fiber.
  • FIG 3 is a schematic cross-sectional view of a light receiving unit according to an embodiment of the present invention.
  • the light receiving unit 20 is installed under the primary lens 11 and the primary lens 11 to receive the light emitted from the light source unit 10, and is received by the primary lens 11. It comprises a secondary lens 12 that focuses a light.
  • the primary lens 11 and the secondary lens 12 implemented by the Fresnel lens is preferably installed to face in opposite directions to each other to change the path of the light.
  • the primary lens 11 passes the light incident at the focus of the Fresnel lens perpendicular to the lens,
  • the light incident perpendicularly to the secondary lens 12 by the primary lens 11 passes through the secondary lens 12 installed in the opposite direction to the primary lens 11 and is then focused at the focal point.
  • the light receiving unit 20 may further include a top plate 13 having a guide hole 13a for guiding light into the light receiving unit 20 at a focal position of the primary lens 11.
  • the upper plate 13 is installed on the primary lens 11, but is preferably installed at the focal length of the primary lens 11.
  • the light receiving unit 20 may further include a lower plate 14 having a hole 14a formed at a focal position of the secondary lens 12.
  • the lower plate 14 is installed below the secondary lens 12, but is preferably installed at the focal length of the secondary lens 12.
  • the light stimulator 30 is integrally connected to the hole 14a formed in the lower plate 14.
  • the light stimulation part 30 is connected to and installed in the hole 14a formed at the focal point of the secondary lens 12, the light that has focused on the light after passing through the secondary lens 12 passes through the light stimulus.
  • the optical fiber which is transmitted to the optical fiber, which is a part 30, receives the light, and the optical stimulation part 30 is applied to the nerve tissue to stimulate the brain tissue.
  • a guide line 15 is installed outside the primary lens 11 of the light receiving unit 20, and a reflector for inducing diffuse reflection may be applied to the guide line 15.
  • the light irradiated from the light source unit 10 passes through the guide hole 13a of the light receiving unit 20 and enters into the guide line 15 of the primary lens 11 to be incident vertically through the primary lens 11.
  • the light incident on the secondary lens 12 by the primary lens 11 passes through the secondary lens 12 and then collects in focus.
  • the light irradiated from the light source unit 10 does not enter the guide line 15 of the primary lens 11 despite passing through the guide hole 13a, it is notified to the outside and irradiated from the light source unit 10. Aim the light to enter the guide line (15) inside.
  • the light that does not enter into the guide line 15 of the primary lens 11 is reflected by a reflector applied to the outside of the guide line 15, the outside is irradiated from the light source unit 10 through the reflected light Although the light passes through the guide hole 13a, it can be seen that the light cannot enter the guide line 15 of the primary lens 11.
  • FIG 5 is a plan view of a light receiving unit according to another exemplary embodiment of the present invention.
  • the light receiving unit 20 is an embodiment except for the electrical signal generator 16, the RF transmitter 18, the driver 17, and the power supply unit 19 installed on the upper plate 13. Since the light receiving unit 20 is substantially the same, the same reference numerals are used for corresponding components, and a detailed description thereof will be omitted.
  • the guide line 15 installed at the outer side of the primary lens 11 may be omitted.
  • the light receiving unit 20 includes a plurality of electric signal generators 16, an RF transmitter 18, a driver 17, and a power supply 19.
  • the plurality of electrical signal generators 16 are installed around the guide hole 13a formed in the upper plate 13 to generate an electrical signal when the light emitted from the light source unit 10 is received.
  • the light irradiated from the light source unit 10 should be incident to the guide hole 13a formed in the upper plate 13.
  • the light irradiated from the light source unit 10 does not enter the guide hole 13a and the guide hole 13a does not enter the guide hole 13a.
  • the electrical signal generator 16 When incident to the electrical signal generator 16 installed in the periphery, the electrical signal generator 16 generates and outputs an electrical signal as it receives light.
  • the electrical signal generator 16 may be implemented with a photo diode, a photo transistor, or the like.
  • the RF transmitter 18 generates and transmits an RF signal.
  • the driver 17 When the driver 17 receives an electrical signal of a predetermined voltage or higher from any one of the electrical signal generators 16, the driver 17 outputs a driving signal to the RF transmitter 18 to drive the RF transmitter 18.
  • the driver 17 may be implemented as a microprocessor, a logic element (eg, a logic sum gate), or the like.
  • the power supply unit 19 supplies power to the plurality of electrical signal generators 16, the RF transmitter 18, and the driver 17.
  • the power supply unit 19 may be implemented as a rechargeable battery, or may be implemented such that the rechargeable battery is charged with the electric signal generated by the electric signal generator 16 when receiving the light.
  • FIG. 6 is a view schematically showing the configuration of a wireless cranial nerve stimulation system according to another embodiment of the present invention.
  • the wireless cranial nerve stimulation system according to another embodiment of the present invention is substantially the same as the wireless cranial nerve stimulation system according to an embodiment except for the camera 40, the reflection mirror 50, and the control unit 60, the corresponding configuration
  • the same reference numerals are used for the elements, and detailed description thereof will be omitted.
  • the light receiver 20 includes a guide line 15 as in the embodiment of FIG. 4.
  • the wireless cranial nerve stimulation system includes a camera 40, a reflection mirror 50, and a controller 60.
  • the living body 1 which is the measurement target on which the light receiving unit 20 is mounted, is located at the bottom of the experimental box, and the light source unit 10 and the camera 40 are provided.
  • the reflection mirror 50 and the like will be described taking an environment provided on the ceiling of an experimental box as an example. However, this is merely an example, and the installation positions of the light source unit 10, the camera 40, the reflective mirror 50, and the like applied to the present invention are not limited thereto.
  • the camera 40 photographs the living body 1 as a measurement target. Specifically, the upper plate plate 13 of the light receiving unit 20 mounted on the head of the living body 1 to be measured is photographed, and the captured image signal is transmitted to the controller 60.
  • the reflecting mirror 50 reflects the light emitted from the light source unit 10 and transmits the light reflected to the light receiving unit 20, and the angle is adjusted under the control of the controller 60.
  • the controller 60 processes the image signal received from the camera 40 and outputs the image signal to a monitor (not shown), and emits light to the light receiving unit 20 according to a user's manipulation of the image signal output to the monitor (not shown).
  • the light emitted from the light source unit 10 passes through the guide hole 13a of the light receiving unit 20 by controlling the direction of the light source unit 10 to be irradiated or by controlling the angle of the reflecting mirror 50. To enter into the guideline (15).
  • a user who watches the top plate 13 of the light receiving unit 20 photographed through the camera 40 with a monitor may guide light of the primary lens 11 to the light emitted from the light source unit 10. If it is confirmed that the light is not reflected inside the line 15 and is reflected by the reflector applied to the outside of the guide line 15, the light emitted from the light source 10 may be manipulated by manipulating the direction of the light source 10. It passes through the guide hole 13a of 20) to enter the guide line 15 of the primary lens 11. Alternatively, the light of the light source unit 10 reflected by the reflecting mirror 50 by controlling the angle of the reflecting mirror 50 passes through the guide hole 13a of the light receiving unit 20 to guide lines 15 of the primary lens 11. ) To enter inside.
  • the controller 60 analyzes the image signal received from the camera 40 in real time and the light irradiated from the light source unit 10 passes through the guide hole 13a of the light receiving unit 20 to guide the primary lens 11.
  • the direction of the light source unit 10 may be automatically controlled to enter the line 15, or the angle of the reflective mirror 50 may be automatically controlled.
  • the controller 60 analyzes the image signal received from the camera 40 in real time, and when the light reflected by the reflector applied outside the guide line 15 is confirmed, the light irradiated from the light source unit 10 The light emitted from the light source unit 10 passes through the guide hole 13a of the light receiving unit 20 and determines that the guide line 15 of the primary lens 11 has not entered the guide line 15. The direction of the light source unit 10 is precisely readjusted to enter the guide line 15, or the angle of the reflecting mirror 50 is precisely readjusted.
  • FIG. 7 is a view schematically showing the configuration of a wireless cranial nerve stimulation system according to another embodiment of the present invention.
  • the wireless cranial nerve stimulation system according to another embodiment of the present invention is substantially the same as the wireless cranial nerve stimulation system according to an embodiment except for the RF receiver 70, the reflection mirror 50, and the controller 60.
  • the same reference numerals are used for components to be described, and detailed description thereof will be omitted.
  • the light receiver 20 uses the electrical signal generator 16, the RF transmitter 18, the driver 17, etc. as in the other embodiment of FIG. 5. It is preferable to comprise.
  • the wireless cranial nerve stimulation system includes an RF receiver 70, a reflection mirror 50, and a controller 60.
  • the living body 1 which is the measurement target equipped with the light receiving unit 20, is located at the bottom of the experimental box, and the light source unit 10 and the RF receiver 70 ),
  • the reflection mirror 50 and the like will be described taking an environment provided on the ceiling of the experimental box as an example.
  • this is merely an example, and the installation positions of the light source unit 10, the RF receiver 70, the reflecting mirror 50, and the like applied to the present invention are not limited thereto.
  • the RF receiver 70 receives an RF signal output from the RF transmitter 18 of the light receiver 20 mounted on the head of the living body 1 to be measured.
  • the reflecting mirror 50 reflects the light emitted from the light source unit 10 and transmits the light reflected to the light receiving unit 20, and the angle is adjusted under the control of the controller 60.
  • the controller 60 processes the RF signal received from the RF receiver 70 in real time so that light emitted from the light source 10 passes through the guide hole 13a of the light receiver 20 to guide the primary lens 11. 15, the direction of the light source unit 10 may be automatically controlled to enter the inside, or the angle of the reflective mirror 50 may be automatically controlled.
  • the light irradiated from the light source unit 10 should be incident to the guide hole 13a formed in the upper plate 13, and the light irradiated from the light source unit 10 does not enter the guide hole 13a and is guided.
  • the electric signal generator 16 When incident on the electric signal generator 16 provided around the hole 13a, the electric signal generator 16 generates and outputs an electric signal as it receives light, and generates a driver according to the generation of the electric signal.
  • the RF receiver 70 receives the RF signal output from the RF transmitter 18.
  • the controller 60 determines that the light irradiated from the light source unit 10 does not enter the guide hole 13a and is irradiated from the light source unit 10.
  • the light source unit 10 is precisely reoriented so that light is incident on the guide hole 13a of the light receiving unit 20, or the angle of the reflecting mirror 50 is precisely readjusted.
  • the light source unit 10 is installed on the ceiling of the experimental box, and the light receiving unit 20 and the light stimulating unit 30 are attached to the living body 1. Therefore, the experiment or test can be performed without disturbing the movement of the living body 1.
  • Embodiments relate to a wireless cranial nerve stimulation system.

Abstract

The present invention relates to a wireless optical brain nerve stimulation system. The wireless optical brain nerve stimulation system includes: a light source unit emitting light; a light receiving unit mounted on a target living body to be measured to receive the light emitted from the light source unit; and an optical stimulation unit applying the light received from the light receiving unit to nerve tissue to stimulate the nerve tissue. According to the wireless optical brain nerve stimulation system, since the target living body to be measured and the light source unit are physically separated from each other, the target living body to be measured may not be restricted in movement.

Description

무선 뇌신경 광 자극 시스템Wireless cranial nerve stimulation system
실시예들은 무선 뇌신경 광 자극 시스템에 관한 것이다.Embodiments relate to a wireless cranial nerve stimulation system.
전기 또는 빛을 이용한 뇌 자극 기술은 환자의 병을 치료하는 데 사용되며, 동시에 인간 외의 동물들에게 적용하여 뇌의 기능을 밝히는데 사용되고 있다.Electric or light brain stimulation technology is used to treat patients' diseases, and at the same time applied to animals other than humans to reveal the brain function.
이 중에서 빛을 이용하여 뇌신경을 자극하는 뇌신경 광 자극 시스템은 특정 파장대의 빛에 의해서만 자극되는 몇몇 채널 및 효소를 신경 세포에 발현시킨 후, 특정 파장대의 빛을 조명해줌으로써 신경 세포를 손상시키지 않고 특정 종류의 신경 세포만 선택적으로 자극/억제한다.Among them, the cranial nerve stimulation system that stimulates the cranial nerve using light expresses some channels and enzymes that are stimulated only by light of a specific wavelength in the nerve cell, and then illuminates the light of a specific wavelength without causing damage to the nerve cell. Only neurons of a kind are selectively stimulated / inhibited.
도 1은 종래에 사용되던 뇌 자극을 위한 광 자극 시스템의 실시예를 나타낸 도면이다.1 is a view showing an embodiment of a conventional light stimulation system for brain stimulation.
도 1에 도시하는 바와 같이, 종래에는 광섬유를 동물의 뇌 내부에 삽입하고, 광섬유를 외부의 광원부에 연결한다. 광원부에서 발사된 빛은 광원부에 연결되어 있는 광섬유를 통하여 뇌신경에 전달된다.As shown in Fig. 1, a conventional optical fiber is inserted into an animal's brain and the optical fiber is connected to an external light source. Light emitted from the light source unit is transmitted to the cranial nerve through the optical fiber connected to the light source unit.
이 방식은 광자극을 받는 동물과 광원부가 광섬유를 통해 물리적으로 연결되어 있으므로, 광섬유가 광자극을 받는 동물의 자유로운 움직임을 제약한다.In this method, the photo-stimulated animal and the light source are physically connected through the optical fiber, so the optical fiber restricts the free movement of the photo-stimulated animal.
이는 행동 실험에 참여하는 동물에게 잠재적인 스트레스 요인이 되어 실험결과에 부정적으로 작용할 수 있다.This may be a potential stressor for animals participating in behavioral experiments and may adversely affect the experimental results.
아울러, 광자극을 받는 동물의 행동(예를 들어, 한쪽 방향으로 계속 회전하는 행동, 광섬유를 물어뜯는 행동 등)에 의해 광섬유가 손상되거나, 광 자극 시스템이 불안정해질 수 있게 된다.In addition, the behavior of an animal subjected to photostimulation (eg, to continue to rotate in one direction, to bite the optical fiber, etc.) may damage the optical fiber or the optical stimulation system may become unstable.
본 발명의 일 측면에 따르면, 무선 방식으로 뇌신경 광 자극 시스템을 구현하여 측정 대상 생체의 자유로운 움직임을 보장할 수 있는 무선 뇌신경 광 자극 시스템을 제공할 수 있다.According to an aspect of the present invention, it is possible to provide a wireless cranial nerve stimulation system that can ensure the free movement of the subject to be measured by implementing a cranial nerve stimulation system in a wireless manner.
일 실시예에 따른 무선 뇌신경 광 자극 시스템은, 빛을 조사하는 광원부; 측정 대상 생체에 장착되어 상기 광원부에서 조사되는 빛을 수신하는 수광부; 및 상기 수광부에서 수신한 빛을 신경 조직에 인가하여 상기 신경 조직을 자극하는 광 자극부를 포함할 수 있다.Wireless cranial nerve stimulation system according to an embodiment, the light source for irradiating light; A light receiving unit mounted on a living body to be measured to receive light emitted from the light source unit; And an optical stimulator for stimulating the neural tissue by applying the light received from the light receiver to the neural tissue.
본 발명의 일 측면에 따른 무선 뇌신경 광 자극 시스템에 의하면, 측정 대상 생체와 광원부가 물리적으로 분리되어 있으므로, 측정 대상 생체의 움직임에 제약을 주지 않게 된다.According to the wireless cranial nerve stimulation system according to an aspect of the present invention, since the measurement target living body and the light source are physically separated, it does not limit the movement of the measurement target living body.
또한, 수광 캐뉼러에서 수신한 빛을 광섬유를 통해 뇌신경에 전달함으로써, 수광 캐뉼러를 소형화 및 경량화할 수 있게 된다.In addition, by transmitting the light received from the light receiving cannula to the cranial nerve through the optical fiber, it is possible to miniaturize and lighten the light receiving cannula.
도 1은 종래에 사용되던 뇌 자극을 위한 광 자극 시스템의 실시예를 나타낸 도면.1 is a view showing an embodiment of a light stimulation system for brain stimulation used in the prior art.
도 2는 일 실시예에 따른 무선 뇌신경 광 자극 시스템의 구성을 개략적으로 보인 도면.2 is a view schematically showing the configuration of a wireless cranial nerve stimulation system according to an embodiment.
도 3은 본 발명의 일 실시예에 따른 수광부의 단면을 개략적으로 보인 도면.3 is a schematic cross-sectional view of a light receiving unit according to an embodiment of the present invention.
도 4는 본 발명의 일 실시예에 따른 수광부의 평면도.4 is a plan view of a light receiving unit according to an embodiment of the present invention.
도 5는 본 발명의 다른 실시예에 따른 수광부의 평면도.5 is a plan view of a light receiving unit according to another embodiment of the present invention.
도 6은 본 발명의 다른 실시예에 따른 무선 뇌신경 광 자극 시스템의 구성을 개략적으로 보인 도면.Figure 6 is a schematic view showing the configuration of a wireless cranial nerve stimulation system according to another embodiment of the present invention.
도 7은 본 발명의 또 다른 실시예에 따른 무선 뇌신경 광 자극 시스템의 구성을 개략적으로 보인 도면.Figure 7 is a schematic view showing the configuration of a wireless cranial nerve stimulation system according to another embodiment of the present invention.
이하에서, 도면을 참조하여 본 발명의 실시예들에 대하여 상세히 살펴본다.Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.
도 2는 일 실시예에 따른 무선 뇌신경 광 자극 시스템의 구성을 개략적으로 보인 도면이다.2 is a view schematically showing the configuration of a wireless cranial nerve stimulation system according to an embodiment.
도 2를 참조하면, 일 실시예에 따른 무선 뇌신경 광 자극 시스템은 광원부(10), 수광부(20), 광 자극부(30)를 포함하여 이루어진다.Referring to FIG. 2, the wireless cranial nerve stimulation system according to an embodiment includes a light source unit 10, a light receiver 20, and a light stimulator 30.
광원부(10)는 빛을 조사한다.The light source unit 10 irradiates light.
광원부(10)는 발광 다이오드(LED), 레이저 다이오드 등으로 구현될 수 있다.The light source unit 10 may be implemented as a light emitting diode (LED), a laser diode, or the like.
수광부(20)는 측정 대상인 생체(예를 들어, 생쥐)(1)의 머리에 장착되어 광원부(10)에서 조사되는 빛을 수신하고, 수신한 빛을 광 자극부(30)로 전달한다.The light receiving unit 20 is mounted on the head of the living body (for example, the mouse) 1 to be measured to receive light emitted from the light source unit 10, and transmits the received light to the light stimulation unit 30.
수광부(20)는 적어도 하나 이상의 렌즈를 포함하여 이루어지며, 렌즈는 볼록 렌즈, 오목 렌즈, 프레스넬 렌즈(Fresnel Lens) 중에서 어느 하나로 이루어지는 것이 바람직하다.The light receiving unit 20 includes at least one lens, and the lens is preferably made of any one of a convex lens, a concave lens, and a Fresnel lens.
본 발명의 실시예에 따른 수광부(20)는 일부가 생체(1)의 몸속에 삽입되는 튜브 형태로 이루어질 수 있다. 그러나, 이는 예시적인 것으로서, 본 발명에 적용되는 수광부(20)는 특정 형상 또는 형태를 갖는 것으로 한정되지 않는다.The light receiving unit 20 according to the embodiment of the present invention may be formed in a tube shape, a part of which is inserted into the body of the living body 1. However, this is merely exemplary, and the light receiving unit 20 applied to the present invention is not limited to having a specific shape or form.
한편, 광 자극부(30)는 측정 대상인 생체(1)의 뇌 내부에 삽입되어 뇌신경 조직과 연결되며, 수광부(20)에서 수신한 빛을 뇌신경 조직에 인가하여 뇌신경 조직을 자극한다.On the other hand, the optical stimulation unit 30 is inserted into the brain of the living body (1) to be measured and connected to the cranial nerve tissue, and stimulates the cranial nerve tissue by applying the light received from the light receiving unit 20 to the cranial nerve tissue.
광 자극부(30)는 광섬유로 구현될 수 있다.The optical stimulation unit 30 may be implemented with an optical fiber.
도 3은 본 발명의 일 실시예에 따른 수광부의 단면을 개략적으로 보인 도면이다.3 is a schematic cross-sectional view of a light receiving unit according to an embodiment of the present invention.
도 3에 도시하는 바와 같이, 수광부(20)는 광원부(10)에서 조사되는 빛을 수신하는 1차 렌즈(11)와 1차 렌즈(11)의 아래에 설치되어 1차 렌즈(11)에서 수신한 빛을 초점으로 모아주는 2차 렌즈(12)를 포함하여 이루어진다.As shown in FIG. 3, the light receiving unit 20 is installed under the primary lens 11 and the primary lens 11 to receive the light emitted from the light source unit 10, and is received by the primary lens 11. It comprises a secondary lens 12 that focuses a light.
본 발명의 실시예에서는 1차 렌즈(11)와 2차 렌즈(12)가 모두 프레스넬 렌즈로 구현되는 경우를 예를 들어 설명한다.In the exemplary embodiment of the present invention, a case where both the primary lens 11 and the secondary lens 12 are implemented as Fresnel lenses will be described as an example.
프레스넬 렌즈로 구현된 1차 렌즈(11)와 2차 렌즈(12)는 서로 반대 방향을 향하도록 설치되어 빛의 경로를 바꾸는 것이 바람직하다.The primary lens 11 and the secondary lens 12 implemented by the Fresnel lens is preferably installed to face in opposite directions to each other to change the path of the light.
구체적으로, 1차 렌즈(11)와 2차 렌즈(12)를 서로 반대 방향을 향하도록 설치함으로써, 1차 렌즈(11)는 프레스넬 렌즈의 초점에서 입사된 빛을 렌즈와 수직으로 통과시키고, 1차 렌즈(11)에 의해 2차 렌즈(12)에 수직으로 입사한 빛은 1차 렌즈(11)와 반대 방향으로 설치된 2차 렌즈(12)를 통과한 후 초점에 모이게 된다.Specifically, by installing the primary lens 11 and the secondary lens 12 to face in the opposite direction, the primary lens 11 passes the light incident at the focus of the Fresnel lens perpendicular to the lens, The light incident perpendicularly to the secondary lens 12 by the primary lens 11 passes through the secondary lens 12 installed in the opposite direction to the primary lens 11 and is then focused at the focal point.
수광부(20)는 1차 렌즈(11)의 초점 위치에 수광부(20) 내로 빛이 입사되도록 안내하는 가이드 홀(13a)이 형성되어 있는 상판 플레이트(13)를 더 포함하여 이루어질 수 있다.The light receiving unit 20 may further include a top plate 13 having a guide hole 13a for guiding light into the light receiving unit 20 at a focal position of the primary lens 11.
상판 플레이트(13)는 1차 렌즈(11)의 위에 설치되되, 1차 렌즈(11)의 초점 거리에 설치되는 것이 바람직하다.The upper plate 13 is installed on the primary lens 11, but is preferably installed at the focal length of the primary lens 11.
또한, 수광부(20)는 2차 렌즈(12)의 초점 위치에 홀(14a)이 형성되어 있는 하판 플레이트(14)를 더 포함하여 이루어질 수 있다.In addition, the light receiving unit 20 may further include a lower plate 14 having a hole 14a formed at a focal position of the secondary lens 12.
하판 플레이트(14)는 2차 렌즈(12)의 아래에 설치되되, 2차 렌즈(12)의 초점 거리에 설치되는 것이 바람직하다.The lower plate 14 is installed below the secondary lens 12, but is preferably installed at the focal length of the secondary lens 12.
하판 플레이트(14)에 형성되어 있는 홀(14a)에는 광 자극부(30)가 일체로 연결 설치된다.The light stimulator 30 is integrally connected to the hole 14a formed in the lower plate 14.
이와 같이, 2차 렌즈(12)의 초점 위치에 형성되는 홀(14a)에 광 자극부(30)가 연결 설치됨에 따라, 2차 렌즈(12)를 통과한 후 초점에 모이게 된 빛은 광 자극부(30)인 광섬유로 전달되고, 빛을 전달받은 광 자극부(30)인 광섬유는 전달받은 빛을 뇌신경 조직에 인가하여 뇌신경 조직을 자극한다.As such, as the light stimulation part 30 is connected to and installed in the hole 14a formed at the focal point of the secondary lens 12, the light that has focused on the light after passing through the secondary lens 12 passes through the light stimulus. The optical fiber, which is transmitted to the optical fiber, which is a part 30, receives the light, and the optical stimulation part 30 is applied to the nerve tissue to stimulate the brain tissue.
한편, 수광부(20)의 1차 렌즈(11) 외곽에는 도 4에 도시하는 바와 같이 가이드 라인(15)이 설치되며, 가이드 라인(15)에는 난반사를 유도하는 반사체가 도포될 수 있다.Meanwhile, as illustrated in FIG. 4, a guide line 15 is installed outside the primary lens 11 of the light receiving unit 20, and a reflector for inducing diffuse reflection may be applied to the guide line 15.
광원부(10)에서 조사된 빛은 수광부(20)의 가이드 홀(13a)을 통과하여 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입되어야 1차 렌즈(11)를 통해 수직으로 입사하고, 1차 렌즈(11)에 의해 2차 렌즈(12)로 수직 입사한 빛은 2차 렌즈(12)를 통과한 후 초점에 모이게 된다. 그러나, 광원부(10)에서 조사된 빛이 가이드 홀(13a)을 통과했음에도 불구하고 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입하지 못하는 경우에는 이를 외부에 알려 광원부(10)에서 조사되는 빛을 재조준하여 빛이 가이드 라인(15) 안쪽으로 진입하도록 한다. 이때, 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입하지 못한 빛은 가이드 라인(15) 외곽에 도포되어 있는 반사체에 의해 반사되며, 외부에서는 반사된 빛을 통해 광원부(10)에서 조사된 빛이 가이드 홀(13a)을 통과했음에도 불구하고 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입하지 못했음을 알 수 있게 된다.The light irradiated from the light source unit 10 passes through the guide hole 13a of the light receiving unit 20 and enters into the guide line 15 of the primary lens 11 to be incident vertically through the primary lens 11. The light incident on the secondary lens 12 by the primary lens 11 passes through the secondary lens 12 and then collects in focus. However, when the light irradiated from the light source unit 10 does not enter the guide line 15 of the primary lens 11 despite passing through the guide hole 13a, it is notified to the outside and irradiated from the light source unit 10. Aim the light to enter the guide line (15) inside. At this time, the light that does not enter into the guide line 15 of the primary lens 11 is reflected by a reflector applied to the outside of the guide line 15, the outside is irradiated from the light source unit 10 through the reflected light Although the light passes through the guide hole 13a, it can be seen that the light cannot enter the guide line 15 of the primary lens 11.
도 5는 본 발명의 다른 실시예에 따른 수광부의 평면도이다.5 is a plan view of a light receiving unit according to another exemplary embodiment of the present invention.
본 발명의 다른 실시예에 따른 수광부(20)는 상판 플레이트(13)에 설치되는 전기 신호 발생부(16), RF 송신부(18), 구동부(17), 전원부(19)를 제외하고 일 실시예에 따른 수광부(20)와 실질적으로 동일하므로 대응하는 구성 요소에 대해서는 동일한 도면 부호를 사용하고, 이에 대한 상세한 설명은 생략한다.The light receiving unit 20 according to another embodiment of the present invention is an embodiment except for the electrical signal generator 16, the RF transmitter 18, the driver 17, and the power supply unit 19 installed on the upper plate 13. Since the light receiving unit 20 is substantially the same, the same reference numerals are used for corresponding components, and a detailed description thereof will be omitted.
다만, 본 발명의 다른 실시예에 따른 수광부(20)에서는 1차 렌즈(11)의 외곽에 설치되는 가이드 라인(15)이 생략될 수 있다.However, in the light receiving unit 20 according to another embodiment of the present invention, the guide line 15 installed at the outer side of the primary lens 11 may be omitted.
도 5에 도시하는 바와 같이, 본 발명의 다른 실시예에 따른 수광부(20)는 복수의 전기 신호 발생부(16), RF 송신부(18), 구동부(17), 전원부(19)를 포함한다.As shown in FIG. 5, the light receiving unit 20 according to another embodiment of the present invention includes a plurality of electric signal generators 16, an RF transmitter 18, a driver 17, and a power supply 19.
복수의 전기 신호 발생부(16)는 상판 플레이트(13)에 형성되어 있는 가이드 홀(13a) 주변에 설치되어 광원부(10)에서 조사되는 빛을 수신하게 되면 전기 신호를 발생시킨다.The plurality of electrical signal generators 16 are installed around the guide hole 13a formed in the upper plate 13 to generate an electrical signal when the light emitted from the light source unit 10 is received.
광원부(10)에서 조사되는 빛은 상판 플레이트(13)에 형성되어 있는 가이드 홀(13a)로 입사되어야 하는데, 광원부(10)에서 조사된 빛이 가이드 홀(13a)로 입사되지 못하고 가이드 홀(13a) 주변에 설치되어 있는 전기 신호 발생부(16)에 입사된 경우, 전기 신호 발생부(16)는 빛을 수신함에 따라 전기 신호를 발생시켜 출력한다.The light irradiated from the light source unit 10 should be incident to the guide hole 13a formed in the upper plate 13. The light irradiated from the light source unit 10 does not enter the guide hole 13a and the guide hole 13a does not enter the guide hole 13a. When incident to the electrical signal generator 16 installed in the periphery, the electrical signal generator 16 generates and outputs an electrical signal as it receives light.
전기 신호 발생부(16)는 포토 다이오드, 포토 트랜지스터 등으로 구현될 수 있다.The electrical signal generator 16 may be implemented with a photo diode, a photo transistor, or the like.
RF 송신부(18)는 RF 신호를 생성하여 송출한다.The RF transmitter 18 generates and transmits an RF signal.
구동부(17)는 복수의 전기 신호 발생부(16) 중에서 어느 하나로부터 기설정된 전압 이상의 전기 신호를 입력받으면 RF 송신부(18)로 구동 신호를 출력하여 RF 송신부(18)를 구동시킨다.When the driver 17 receives an electrical signal of a predetermined voltage or higher from any one of the electrical signal generators 16, the driver 17 outputs a driving signal to the RF transmitter 18 to drive the RF transmitter 18.
구동부(17)는 마이크로 프로세서, 논리 소자(예를 들어, 논리합 게이트) 등으로 구현될 수 있다.The driver 17 may be implemented as a microprocessor, a logic element (eg, a logic sum gate), or the like.
전원부(19)는 복수의 전기 신호 발생부(16), RF 송신부(18), 구동부(17)에 전원을 공급한다.The power supply unit 19 supplies power to the plurality of electrical signal generators 16, the RF transmitter 18, and the driver 17.
전원부(19)는 재충전이 가능한 배터리(Rechargeable battery)로 구현될 수 있으며, 전기 신호 발생부(16)가 빛을 수신함에 따라 발생시킨 전기 신호로 재충전이 가능한 배터리가 충전되도록 구현될 수도 있다.The power supply unit 19 may be implemented as a rechargeable battery, or may be implemented such that the rechargeable battery is charged with the electric signal generated by the electric signal generator 16 when receiving the light.
도 6은 본 발명의 다른 실시예에 따른 무선 뇌신경 광 자극 시스템의 구성을 개략적으로 보인 도면이다.6 is a view schematically showing the configuration of a wireless cranial nerve stimulation system according to another embodiment of the present invention.
본 발명의 다른 실시예에 따른 무선 뇌신경 광 자극 시스템은 카메라(40), 반사 거울(50), 제어부(60)를 제외하고 일 실시예에 따른 무선 뇌신경 광 자극 시스템과 실질적으로 동일하므로 대응하는 구성 요소에 대해서는 동일한 도면 부호를 사용하고, 이에 대한 상세한 설명은 생략한다.The wireless cranial nerve stimulation system according to another embodiment of the present invention is substantially the same as the wireless cranial nerve stimulation system according to an embodiment except for the camera 40, the reflection mirror 50, and the control unit 60, the corresponding configuration The same reference numerals are used for the elements, and detailed description thereof will be omitted.
다만, 본 발명의 다른 실시예에 따른 무선 뇌신경 광 자극 시스템에서는 수광부(20)가 도 4의 일 실시예와 같이 가이드 라인(15)을 포함하여 이루어지는 것이 바람직하다.However, in the wireless cranial nerve stimulation system according to another embodiment of the present invention, it is preferable that the light receiver 20 includes a guide line 15 as in the embodiment of FIG. 4.
도 6에 도시하는 바와 같이, 본 발명의 다른 실시예에 따른 무선 뇌신경 광 자극 시스템은 카메라(40), 반사 거울(50), 제어부(60)를 포함한다.As shown in FIG. 6, the wireless cranial nerve stimulation system according to another embodiment of the present invention includes a camera 40, a reflection mirror 50, and a controller 60.
본 발명의 실시예가 실험용 상자 안에서 실시된다고 가정했을 때, 본 발명의 실시예에서 수광부(20)가 장착된 측정 대상인 생체(1)는 실험용 상자의 바닥에 위치하고, 광원부(10), 카메라(40), 반사 거울(50) 등은 실험용 상자의 천정에 설치되는 환경을 예를 들어 설명한다. 그러나, 이는 예시적인 것으로서, 본 발명에 적용되는 광원부(10), 카메라(40), 반사 거울(50) 등의 설치 위치는 이에 한정되지 않음은 물론이다.Assuming that the embodiment of the present invention is carried out in the experimental box, in the embodiment of the present invention, the living body 1, which is the measurement target on which the light receiving unit 20 is mounted, is located at the bottom of the experimental box, and the light source unit 10 and the camera 40 are provided. , The reflection mirror 50 and the like will be described taking an environment provided on the ceiling of an experimental box as an example. However, this is merely an example, and the installation positions of the light source unit 10, the camera 40, the reflective mirror 50, and the like applied to the present invention are not limited thereto.
카메라(40)는 측정 대상인 생체(1)를 촬영한다. 구체적으로, 측정 대상인 생체(1)의 머리에 장착되어 있는 수광부(20)의 상판 플레이트(13)를 촬영하고, 촬영한 영상 신호를 제어부(60)로 전달한다.The camera 40 photographs the living body 1 as a measurement target. Specifically, the upper plate plate 13 of the light receiving unit 20 mounted on the head of the living body 1 to be measured is photographed, and the captured image signal is transmitted to the controller 60.
반사 거울(50)은 광원부(10)에서 조사되는 빛을 반사하여 수광부(20)에 전달하는 것으로, 제어부(60)의 제어하에 각도가 조절된다.The reflecting mirror 50 reflects the light emitted from the light source unit 10 and transmits the light reflected to the light receiving unit 20, and the angle is adjusted under the control of the controller 60.
제어부(60)는 카메라(40)로부터 전달받은 영상 신호를 처리하여 모니터(미도시)로 출력하고, 모니터(미도시)에 출력되는 영상 신호를 확인한 사용자의 조작에 따라 수광부(20)로 빛을 조사하는 광원부(10)의 방향을 제어하거나, 반사 거울(50)의 각도를 제어하여 광원부(10)에서 조사되는 빛이 수광부(20)의 가이드 홀(13a)을 통과하여 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입하도록 한다.The controller 60 processes the image signal received from the camera 40 and outputs the image signal to a monitor (not shown), and emits light to the light receiving unit 20 according to a user's manipulation of the image signal output to the monitor (not shown). The light emitted from the light source unit 10 passes through the guide hole 13a of the light receiving unit 20 by controlling the direction of the light source unit 10 to be irradiated or by controlling the angle of the reflecting mirror 50. To enter into the guideline (15).
구체적으로, 카메라(40)를 통해 촬영되는 수광부(20)의 상판 플레이트(13)를 모니터(미도시)로 주시하고 있던 사용자는 광원부(10)에서 조사되는 빛이 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입하지 못하고, 가이드 라인(15) 외곽에 도포되어 있는 반사체에 의해 반사되는 것을 확인하게 되면, 광원부(10)의 방향을 조작하여 광원부(10)에서 조사되는 빛이 수광부(20)의 가이드 홀(13a)을 통과하여 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입되도록 한다. 또는 반사 거울(50)의 각도를 제어하여 반사 거울(50)에서 반사되는 광원부(10)의 빛이 수광부(20)의 가이드 홀(13a)을 통과하여 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입되도록 한다.In detail, a user who watches the top plate 13 of the light receiving unit 20 photographed through the camera 40 with a monitor (not shown) may guide light of the primary lens 11 to the light emitted from the light source unit 10. If it is confirmed that the light is not reflected inside the line 15 and is reflected by the reflector applied to the outside of the guide line 15, the light emitted from the light source 10 may be manipulated by manipulating the direction of the light source 10. It passes through the guide hole 13a of 20) to enter the guide line 15 of the primary lens 11. Alternatively, the light of the light source unit 10 reflected by the reflecting mirror 50 by controlling the angle of the reflecting mirror 50 passes through the guide hole 13a of the light receiving unit 20 to guide lines 15 of the primary lens 11. ) To enter inside.
또한, 제어부(60)는 카메라(40)로부터 전달받은 영상 신호를 실시간 분석하여 광원부(10)에서 조사되는 빛이 수광부(20)의 가이드 홀(13a)을 통과하여 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입되도록 광원부(10)의 방향을 자동 제어하거나, 반사 거울(50)의 각도를 자동 제어할 수 있다.In addition, the controller 60 analyzes the image signal received from the camera 40 in real time and the light irradiated from the light source unit 10 passes through the guide hole 13a of the light receiving unit 20 to guide the primary lens 11. The direction of the light source unit 10 may be automatically controlled to enter the line 15, or the angle of the reflective mirror 50 may be automatically controlled.
구체적으로, 제어부(60)는 카메라(40)로부터 전달받은 영상 신호를 실시간 분석하여 가이드 라인(15) 외곽에 도포되어 있는 반사체에 의해 반사되는 빛이 확인되면, 광원부(10)에서 조사되는 빛이 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입하지 못한 것으로 판단하여, 광원부(10)에서 조사되는 빛이 수광부(20)의 가이드 홀(13a)을 통과하여 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입되도록 광원부(10)의 방향을 정밀하게 재조준하거나, 반사 거울(50)의 각도를 정밀하게 다시 조정한다.In detail, the controller 60 analyzes the image signal received from the camera 40 in real time, and when the light reflected by the reflector applied outside the guide line 15 is confirmed, the light irradiated from the light source unit 10 The light emitted from the light source unit 10 passes through the guide hole 13a of the light receiving unit 20 and determines that the guide line 15 of the primary lens 11 has not entered the guide line 15. The direction of the light source unit 10 is precisely readjusted to enter the guide line 15, or the angle of the reflecting mirror 50 is precisely readjusted.
도 7은 본 발명의 또 다른 실시예에 따른 무선 뇌신경 광 자극 시스템의 구성을 개략적으로 보인 도면이다.7 is a view schematically showing the configuration of a wireless cranial nerve stimulation system according to another embodiment of the present invention.
본 발명의 또 다른 실시예에 따른 무선 뇌신경 광 자극 시스템은 RF 수신부(70), 반사 거울(50), 제어부(60)를 제외하고 일 실시예에 따른 무선 뇌신경 광 자극 시스템과 실질적으로 동일하므로 대응하는 구성 요소에 대해서는 동일한 도면 부호를 사용하고, 이에 대한 상세한 설명은 생략한다.The wireless cranial nerve stimulation system according to another embodiment of the present invention is substantially the same as the wireless cranial nerve stimulation system according to an embodiment except for the RF receiver 70, the reflection mirror 50, and the controller 60. The same reference numerals are used for components to be described, and detailed description thereof will be omitted.
다만, 본 발명의 또 다른 실시예에 따른 무선 뇌신경 광 자극 시스템에서는 수광부(20)가 도 5의 다른 실시예와 같이 전기 신호 발생부(16), RF 송신부(18), 구동부(17) 등을 포함하여 이루어지는 것이 바람직하다.However, in the wireless cranial nerve stimulation system according to another embodiment of the present invention, the light receiver 20 uses the electrical signal generator 16, the RF transmitter 18, the driver 17, etc. as in the other embodiment of FIG. 5. It is preferable to comprise.
도 7에 도시하는 바와 같이, 본 발명의 또 다른 실시예에 따른 무선 뇌신경 광 자극 시스템은 RF 수신부(70), 반사 거울(50), 제어부(60)를 포함한다.As shown in FIG. 7, the wireless cranial nerve stimulation system according to another embodiment of the present invention includes an RF receiver 70, a reflection mirror 50, and a controller 60.
본 발명의 실시예가 실험용 상자 안에서 실시된다고 가정했을 때, 본 발명의 실시예에서 수광부(20)가 장착된 측정 대상인 생체(1)는 실험용 상자의 바닥에 위치하고, 광원부(10), RF 수신부(70), 반사 거울(50) 등은 실험용 상자의 천정에 설치되는 환경을 예를 들어 설명한다. 그러나, 이는 예시적인 것으로서, 본 발명에 적용되는 광원부(10), RF 수신부(70), 반사 거울(50) 등의 설치 위치는 이에 한정되지 않음은 물론이다.Assuming that the embodiment of the present invention is carried out in the experimental box, in the embodiment of the present invention, the living body 1, which is the measurement target equipped with the light receiving unit 20, is located at the bottom of the experimental box, and the light source unit 10 and the RF receiver 70 ), The reflection mirror 50 and the like will be described taking an environment provided on the ceiling of the experimental box as an example. However, this is merely an example, and the installation positions of the light source unit 10, the RF receiver 70, the reflecting mirror 50, and the like applied to the present invention are not limited thereto.
RF 수신부(70)는 측정 대상인 생체(1)의 머리에 장착된 수광부(20)의 RF 송신부(18)에서 출력하는 RF 신호를 수신한다.The RF receiver 70 receives an RF signal output from the RF transmitter 18 of the light receiver 20 mounted on the head of the living body 1 to be measured.
반사 거울(50)은 광원부(10)에서 조사되는 빛을 반사하여 수광부(20)에 전달하는 것으로, 제어부(60)의 제어하에 각도가 조절된다.The reflecting mirror 50 reflects the light emitted from the light source unit 10 and transmits the light reflected to the light receiving unit 20, and the angle is adjusted under the control of the controller 60.
제어부(60)는 RF 수신부(70)에서 전달받은 RF 신호를 실시간 처리하여 광원부(10)에서 조사되는 빛이 수광부(20)의 가이드 홀(13a)을 통과하여 1차 렌즈(11)의 가이드 라인(15) 안쪽으로 진입되도록 광원부(10)의 방향을 자동 제어하거나, 반사 거울(50)의 각도를 자동 제어할 수 있다.The controller 60 processes the RF signal received from the RF receiver 70 in real time so that light emitted from the light source 10 passes through the guide hole 13a of the light receiver 20 to guide the primary lens 11. 15, the direction of the light source unit 10 may be automatically controlled to enter the inside, or the angle of the reflective mirror 50 may be automatically controlled.
구체적으로, 광원부(10)에서 조사되는 빛은 상판 플레이트(13)에 형성되어 있는 가이드 홀(13a)로 입사되어야 하는데, 광원부(10)에서 조사된 빛이 가이드 홀(13a)로 입사되지 못하고 가이드 홀(13a) 주변에 설치되어 있는 전기 신호 발생부(16)에 입사하게 되는 경우에는 전기 신호 발생부(16)에서 빛을 수신함에 따라 전기 신호를 발생시켜 출력하고, 전기 신호의 발생에 따라 구동부(17)가 RF 송신부(18)를 구동시켜 RF 신호를 출력하게 되면, RF 수신부(70)는 RF 송신부(18)에서 출력하는 RF 신호를 수신하게 된다.Specifically, the light irradiated from the light source unit 10 should be incident to the guide hole 13a formed in the upper plate 13, and the light irradiated from the light source unit 10 does not enter the guide hole 13a and is guided. When incident on the electric signal generator 16 provided around the hole 13a, the electric signal generator 16 generates and outputs an electric signal as it receives light, and generates a driver according to the generation of the electric signal. When the 17 drives the RF transmitter 18 to output the RF signal, the RF receiver 70 receives the RF signal output from the RF transmitter 18.
이와 같이, RF 수신부(70)에서 RF 신호를 수신하게 되면, 제어부(60)는 광원부(10)에서 조사되는 빛이 가이드 홀(13a)로 입사되지 못한 것으로 판단하여, 광원부(10)에서 조사되는 빛이 수광부(20)의 가이드 홀(13a)로 입사되도록 광원부(10)의 방향을 정밀하게 재조준하거나, 반사 거울(50)의 각도를 정밀하게 다시 조정한다.As such, when the RF receiver 70 receives the RF signal, the controller 60 determines that the light irradiated from the light source unit 10 does not enter the guide hole 13a and is irradiated from the light source unit 10. The light source unit 10 is precisely reoriented so that light is incident on the guide hole 13a of the light receiving unit 20, or the angle of the reflecting mirror 50 is precisely readjusted.
이상에서 살펴본 바와 같이, 본 발명의 실시예에 따른 무선 뇌신경 광 자극 시스템에서 광원부(10)는 실험용 상자의 천정에 설치되고, 수광부(20) 및 광 자극부(30)는 생체(1)에 부착되므로, 생체(1)의 움직임을 방해하지 않고 실험 또는 테스트를 진행할 수 있다.As described above, in the wireless cranial nerve stimulation system according to an embodiment of the present invention, the light source unit 10 is installed on the ceiling of the experimental box, and the light receiving unit 20 and the light stimulating unit 30 are attached to the living body 1. Therefore, the experiment or test can be performed without disturbing the movement of the living body 1.
이상에서 살펴본 본 발명은 도면에 도시된 실시예들을 참고로 하여 설명하였으나, 이는 예시적인 것에 불과하며 당해 분야에서 통상의 지식을 가진 자라면 이로부터 다양한 변형 및 실시예의 변형이 가능하다는 점을 이해할 것이다. 그러나, 이와 같은 변형은 본 발명의 기술적 보호범위 내에 있다고 보아야 한다. 따라서, 본 발명의 진정한 기술적 보호범위는 첨부된 특허청구범위의 기술적 사상에 의하여 정해져야 할 것이다.Although the present invention described above has been described with reference to the embodiments illustrated in the drawings, this is merely exemplary and will be understood by those skilled in the art that various modifications and variations can be made therefrom. . However, such modifications should be considered to be within the technical protection scope of the present invention. Therefore, the true technical protection scope of the present invention will be defined by the technical spirit of the appended claims.
실시예들은 무선 뇌신경 광 자극 시스템에 관한 것이다.Embodiments relate to a wireless cranial nerve stimulation system.

Claims (18)

  1. 빛을 조사하는 광원부;A light source unit for irradiating light;
    측정 대상 생체에 장착되어 상기 광원부에서 조사되는 빛을 수신하는 수광부; 및A light receiving unit mounted on a living body to be measured to receive light emitted from the light source unit; And
    상기 수광부에서 수신한 빛을 신경 조직에 인가하여 상기 신경 조직을 자극하는 광 자극부를 포함하는 무선 뇌신경 광 자극 시스템.Wireless light nerve stimulation system comprising a light stimulator for stimulating the neural tissue by applying the light received from the light receiver to the nerve tissue.
  2. 제 1항에 있어서,The method of claim 1,
    상기 수광부는, 적어도 하나 이상의 렌즈를 포함하는 무선 뇌신경 광 자극 시스템.The light receiving unit, the wireless cranial nerve stimulation system comprising at least one lens.
  3. 제 2항에 있어서,The method of claim 2,
    상기 렌즈는, 볼록 렌즈, 오목 렌즈, 프레스넬 렌즈 중에서 어느 하나로 이루어지는 무선 뇌신경 광 자극 시스템.The lens is any one of a convex lens, concave lens, Fresnel lens of the wireless cranial nerve optical stimulation system.
  4. 제 2항에 있어서,The method of claim 2,
    상기 수광부는, 일부가 생체 몸속에 삽입되는 튜브 형태로 이루어지며,The light-receiving portion is formed in the form of a tube, a part of which is inserted into the living body,
    상기 광원부에서 조사되는 빛을 수신하는 1차 렌즈; 및A primary lens for receiving light emitted from the light source unit; And
    상기 1차 렌즈에서 수신한 빛을 초점으로 모아주는 2차 렌즈를 포함하는 무선 뇌신경 광 자극 시스템.Wireless cranial nerve stimulation system comprising a secondary lens for focusing the light received from the primary lens.
  5. 제 4항에 있어서,The method of claim 4, wherein
    상기 1차 렌즈와 상기 2차 렌즈는 서로 반대 방향을 향하도록 설치되는 무선 뇌신경 광 자극 시스템.And the primary lens and the secondary lens are installed to face in opposite directions to each other.
  6. 제 4항에 있어서,The method of claim 4, wherein
    상기 1차 렌즈의 초점 위치에 상기 수광부 내로 빛이 입사되도록 안내하는 가이드 홀이 형성되어 있는 상판 플레이트가 상기 1차 렌즈의 초점 거리에 설치되는 무선 뇌신경 광 자극 시스템.And a top plate having a guide hole for guiding light into the light receiving unit at a focal point of the primary lens is installed at a focal length of the primary lens.
  7. 제 6항에 있어서,The method of claim 6,
    상기 1차 렌즈의 외곽에 설치되며, 난반사를 유도하는 반사체가 도포되어 있는 가이드 라인을 더 포함하는 무선 뇌신경 광 자극 시스템.The wireless cranial nerve stimulation system is installed on the outer side of the primary lens, the guide line is further coated with a reflector for inducing diffuse reflection.
  8. 제 6항에 있어서,The method of claim 6,
    상기 가이드 홀 주변에 설치되어 상기 광원부에서 조사되는 빛을 수신하면 전기 신호를 발생시키는 복수의 전기 신호 발생부;A plurality of electric signal generators installed around the guide hole to generate electric signals when receiving light emitted from the light source unit;
    RF 신호를 생성하여 송출하는 RF 송신부; 및An RF transmitter for generating and transmitting an RF signal; And
    전기 신호 발생에 따라 상기 RF 송신부로 구동 신호를 출력하는 구동부를 더 포함하는 무선 뇌신경 광 자극 시스템.The wireless cranial nerve stimulation system further comprises a driving unit for outputting a driving signal to the RF transmitter in accordance with the electrical signal generation.
  9. 제 8항에 있어서,The method of claim 8,
    상기 구동부는, 마이크로 프로세서 또는 논리 소자로 구현되는 무선 뇌신경 광 자극 시스템.The driving unit, the wireless cranial nerve stimulation system implemented by a microprocessor or a logic element.
  10. 제 4항에 있어서,The method of claim 4, wherein
    상기 2차 렌즈의 초점 위치에 홀이 형성되어 있는 하판 플레이트가 상기 2차 렌즈의 초점 거리에 설치되는 무선 뇌신경 광 자극 시스템.And a lower plate having holes formed at a focal position of the secondary lens at a focal length of the secondary lens.
  11. 제 10항에 있어서,The method of claim 10,
    상기 홀에 광 자극부가 일체로 연결 설치되는 무선 뇌신경 광 자극 시스템.Wireless cranial nerve stimulation system that is installed integrally connected to the optical stimulation unit in the hole.
  12. 제 1항 내지 제 11항 중 어느 한 항에 있어서,The method according to any one of claims 1 to 11,
    사용자 요청에 따라 상기 광원부에서 조사되는 빛을 상기 수광부로 조준시키는 제어부를 더 포함하는 무선 뇌신경 광 자극 시스템.The wireless cranial nerve stimulation system further comprises a control unit for aiming the light irradiated from the light source unit to the light receiving unit according to a user request.
  13. 제 12항에 있어서, The method of claim 12,
    측정 대상 생체를 촬영하는 카메라를 더 포함하는 무선 뇌신경 광 자극 시스템.The wireless cranial nerve stimulation system further comprises a camera for photographing a living body to be measured.
  14. 제 13항에 있어서,The method of claim 13,
    제어부는, 상기 카메라로부터 전달받은 영상 신호를 실시간 분석하여, 상기 광원부에서 조사되는 빛을 상기 수광부로 조준시키는 무선 뇌신경 광 자극 시스템.The control unit is a wireless cranial nerve stimulation system for real-time analysis of the image signal received from the camera, aiming the light irradiated from the light source to the light receiving unit.
  15. 제 12항에 있어서,The method of claim 12,
    상기 광원부에서 조사되는 빛을 반사하여 상기 수광부에 전달하는 반사 거울을 더 포함하며,It further comprises a reflecting mirror reflecting the light irradiated from the light source unit and transmitted to the light receiving unit,
    상기 제어부는, 상기 카메라로부터 전달받은 영상 신호를 실시간 분석하여, 상기 반사 거울의 각도를 제어하는 무선 뇌신경 광 자극 시스템.The control unit, the wireless cranial nerve stimulation system for controlling the angle of the reflection mirror by analyzing the image signal received from the camera in real time.
  16. 제 15항에 있어서,The method of claim 15,
    측정 대상 생체를 촬영하는 카메라를 더 포함하며,Further comprising a camera for taking a measurement target living body,
    상기 제어부는 상기 카메라로부터 전달받은 영상 신호를 분석하여, 상기 반사 거울의 각도를 제어하는 무선 뇌신경 광 자극 시스템.The control unit is a wireless cranial nerve stimulation system for controlling the angle of the reflection mirror by analyzing the image signal received from the camera.
  17. 제 12항에 있어서,The method of claim 12,
    RF 신호를 수신하는 RF 수신부를 더 포함하며,Further comprising an RF receiver for receiving an RF signal,
    상기 제어부는 상기 RF 수신부로부터 전달받은 RF 신호를 분석하여, 상기 광원부에서 조사되는 빛을 상기 수광부로 조준시키는 무선 뇌신경 광 자극 시스템.The control unit analyzes the RF signal received from the RF receiving unit, the wireless cranial nerve stimulation system for aiming the light irradiated from the light source to the light receiving unit.
  18. 제 17항에 있어서,The method of claim 17,
    상기 광원부에서 조사되는 빛을 반사하여 상기 수광부에 전달하는 반사 거울을 더 포함하며,It further comprises a reflecting mirror reflecting the light irradiated from the light source unit and transmitted to the light receiving unit,
    상기 제어부는 상기 RF 수신부로부터 전달받은 RF 신호를 분석하여 상기 반사 거울의 각도를 제어하는 무선 뇌신경 광 자극 시스템.The control unit is a wireless cranial nerve stimulation system for controlling the angle of the reflection mirror by analyzing the RF signal received from the RF receiver.
PCT/KR2012/001870 2012-03-15 2012-03-15 Wireless optical brain nerve stimulation system WO2013137500A1 (en)

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CN109009549A (en) * 2018-08-20 2018-12-18 中国人民解放军军事科学院军事医学研究院 Record the device of animal pharmaceuticals Addictive Behaviors and related brain areas nervous activity rule

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KR20040070952A (en) * 2003-02-05 2004-08-11 주식회사 헬스피아 System for stimulating a spots on the body suitable for acupuncture
JP2006071612A (en) * 2004-09-06 2006-03-16 Niigata Tlo:Kk Method and system for evaluating learning disability
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KR20040070952A (en) * 2003-02-05 2004-08-11 주식회사 헬스피아 System for stimulating a spots on the body suitable for acupuncture
JP2006071612A (en) * 2004-09-06 2006-03-16 Niigata Tlo:Kk Method and system for evaluating learning disability
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109009549A (en) * 2018-08-20 2018-12-18 中国人民解放军军事科学院军事医学研究院 Record the device of animal pharmaceuticals Addictive Behaviors and related brain areas nervous activity rule

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