WO2012149134A8 - Devices and methods for collection and/or manipulation of blood spots or other bodily fluids - Google Patents

Devices and methods for collection and/or manipulation of blood spots or other bodily fluids Download PDF

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Publication number
WO2012149134A8
WO2012149134A8 PCT/US2012/035173 US2012035173W WO2012149134A8 WO 2012149134 A8 WO2012149134 A8 WO 2012149134A8 US 2012035173 W US2012035173 W US 2012035173W WO 2012149134 A8 WO2012149134 A8 WO 2012149134A8
Authority
WO
WIPO (PCT)
Prior art keywords
blood
substrate
methods
bodily fluids
devices
Prior art date
Application number
PCT/US2012/035173
Other languages
French (fr)
Other versions
WO2012149134A1 (en
Inventor
Howard Bernstein
Donald E. Chickering
Shawn Davis
Ping Gong
Kristin HORTON
Scott James
Original Assignee
Seventh Sense Biosystems, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46148950&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2012149134(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Seventh Sense Biosystems, Inc. filed Critical Seventh Sense Biosystems, Inc.
Priority to EP12723286.6A priority Critical patent/EP2701601B1/en
Priority to CN201280021299.8A priority patent/CN103874461B/en
Priority to JP2014508547A priority patent/JP2014516644A/en
Priority to AU2012249683A priority patent/AU2012249683A1/en
Priority to CA2833175A priority patent/CA2833175A1/en
Priority to KR1020137031337A priority patent/KR20140034200A/en
Priority to EP17163359.7A priority patent/EP3235429B1/en
Publication of WO2012149134A1 publication Critical patent/WO2012149134A1/en
Publication of WO2012149134A8 publication Critical patent/WO2012149134A8/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150053Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061Means for enhancing collection
    • A61B5/150099Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
    • AHUMAN NECESSITIES
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    • A61B5/14Devices for taking samples of blood ; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood
    • A61B5/1405Devices for taking blood samples
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    • A61B5/1405Devices for taking blood samples
    • A61B5/1411Devices for taking blood samples by percutaneous method, e.g. by lancet
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    • A61B5/14507Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
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    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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    • A61B5/14539Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
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    • A61B5/14546Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
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    • A61B5/150381Design of piercing elements
    • A61B5/150412Pointed piercing elements, e.g. needles, lancets for piercing the skin
    • A61B5/150419Pointed piercing elements, e.g. needles, lancets for piercing the skin comprising means for capillary action
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    • A61B5/150755Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
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    • A61B5/15Devices for taking samples of blood
    • A61B5/150969Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
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    • A61B5/15101Details
    • A61B5/15103Piercing procedure
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Abstract

The present invention generally relates to systems and methods for receiving blood (or other bodily fluids) from a subject, e.g., from or beneath the skin of a subject. In some cases, the blood (or other bodily fluids) may be deposited on a membrane or other substrate. For example, blood may be absorbed in a substrate, and dried in some cases to produce a dried blood spot. In one aspect, the present invention is generally directed to devices and methods for receiving blood from a subject, e.g., from the skin, using devices including a substance transfer component (which may contain, for example, one or more microneedles), and directing the blood on a substrate, e.g., for absorbing blood. The substrate, in some embodiments, may comprise filter paper or cotton-based paper. After absorption of some blood onto the substrate, the substrate may be removed from the device and shipped or analyzed.
PCT/US2012/035173 2011-04-29 2012-04-26 Devices and methods for collection and/or manipulation of blood spots or other bodily fluids WO2012149134A1 (en)

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