WO2012114327A3 - Retinal prosthesis with efficient processing circuits - Google Patents

Retinal prosthesis with efficient processing circuits Download PDF

Info

Publication number
WO2012114327A3
WO2012114327A3 PCT/IL2012/000057 IL2012000057W WO2012114327A3 WO 2012114327 A3 WO2012114327 A3 WO 2012114327A3 IL 2012000057 W IL2012000057 W IL 2012000057W WO 2012114327 A3 WO2012114327 A3 WO 2012114327A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrodes
processing circuits
efficient processing
retinal prosthesis
group
Prior art date
Application number
PCT/IL2012/000057
Other languages
French (fr)
Other versions
WO2012114327A2 (en
Inventor
Tuvia Liran
Ra'anan Gefen
Original Assignee
Nano-Retina, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nano-Retina, Inc. filed Critical Nano-Retina, Inc.
Priority to EP12748896.3A priority Critical patent/EP2677962B1/en
Publication of WO2012114327A2 publication Critical patent/WO2012114327A2/en
Publication of WO2012114327A3 publication Critical patent/WO2012114327A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36046Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the eye

Abstract

A medical device includes an array of electrodes (26), configured for implantation in contact with tissue in an eye (22) of a living subject. Driver circuitry (46) is configured to drive the electrodes (26) in an alternating pattern, such that different groups of the electrodes are driven to stimulate the tissue during different, predetermined respective time periods. A power sensor (132), may be coupled to deactivate a first group of the electrodes when the available electrical power drops below a predetermined threshold, while a second group of the electrodes remains active. Other embodiments are also described.
PCT/IL2012/000057 2011-02-24 2012-02-02 Retinal prosthesis with efficient processing circuits WO2012114327A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP12748896.3A EP2677962B1 (en) 2011-02-24 2012-02-02 Retinal prosthesis with efficient processing circuits

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/034,516 2011-02-24
US13/034,516 US8571669B2 (en) 2011-02-24 2011-02-24 Retinal prosthesis with efficient processing circuits

Publications (2)

Publication Number Publication Date
WO2012114327A2 WO2012114327A2 (en) 2012-08-30
WO2012114327A3 true WO2012114327A3 (en) 2015-06-18

Family

ID=46719528

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2012/000057 WO2012114327A2 (en) 2011-02-24 2012-02-02 Retinal prosthesis with efficient processing circuits

Country Status (3)

Country Link
US (2) US8571669B2 (en)
EP (1) EP2677962B1 (en)
WO (1) WO2012114327A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9331791B2 (en) 2014-01-21 2016-05-03 Nano Retina Ltd. Transfer of power and data
US9370417B2 (en) 2013-03-14 2016-06-21 Nano-Retina, Inc. Foveated retinal prosthesis
US9566191B2 (en) 2009-02-09 2017-02-14 Nano-Retina, Inc. Retinal prosthesis with visible-light filter

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8150526B2 (en) 2009-02-09 2012-04-03 Nano-Retina, Inc. Retinal prosthesis
US8428740B2 (en) 2010-08-06 2013-04-23 Nano-Retina, Inc. Retinal prosthesis techniques
US8442641B2 (en) 2010-08-06 2013-05-14 Nano-Retina, Inc. Retinal prosthesis techniques
US8718784B2 (en) 2010-01-14 2014-05-06 Nano-Retina, Inc. Penetrating electrodes for retinal stimulation
US8571669B2 (en) 2011-02-24 2013-10-29 Nano-Retina, Inc. Retinal prosthesis with efficient processing circuits
US9720477B2 (en) * 2012-11-21 2017-08-01 Nano-Retina, Inc. Weak power supply operation and control
US10121533B2 (en) 2012-11-21 2018-11-06 Nano-Retina, Inc. Techniques for data retention in memory cells during power interruption
KR20140072524A (en) * 2012-12-05 2014-06-13 현대자동차주식회사 Apparatus for measuring fatigue degree of driver's eye
US9474902B2 (en) 2013-12-31 2016-10-25 Nano Retina Ltd. Wearable apparatus for delivery of power to a retinal prosthesis
CN106691677A (en) * 2015-07-21 2017-05-24 林伯刚 Retina chip driven by light source
WO2017100545A1 (en) 2015-12-10 2017-06-15 Nano-Retina, Inc. Techniques for data retention in memory cells during power interruption
US10272244B2 (en) 2016-11-03 2019-04-30 Nano Retina Ltd. Retinal implant fixation
US10226625B2 (en) 2016-11-03 2019-03-12 Nano Retina Ltd. Surgical techniques for implantation of a retinal implant
KR101856014B1 (en) 2016-12-05 2018-05-11 고려대학교 산학협력단 Artificial retina system
KR101941892B1 (en) * 2017-03-23 2019-01-28 고려대학교 산학협력단 Artificial retina system for improving contrast sensitivity
US10583283B2 (en) 2018-01-31 2020-03-10 Nano-Retina, Inc. Retinal implant with image registration
KR102196461B1 (en) * 2019-08-27 2020-12-29 아주대학교산학협력단 Epiretinal artificial retinal device
CN111603676B (en) * 2020-04-11 2023-04-07 复旦大学 Flexible artificial retina stimulation chip
KR102332169B1 (en) * 2021-02-24 2021-12-01 주식회사 셀리코 Retinal implant system based on augmented reality

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5835250A (en) * 1995-08-23 1998-11-10 Fujitsu Limited Device for driving light emitting element
US6458157B1 (en) * 1997-08-04 2002-10-01 Suaning Gregg Joergen Retinal stimulator
US20040189940A1 (en) * 1999-12-13 2004-09-30 Ernst Kutschbach Method and system for determining the topography for reaction signals of an eye
US20060184245A1 (en) * 2003-06-23 2006-08-17 Heinz-Gerhard Graf Active retina implant with a multiplicity of pixel elements
US7191010B2 (en) * 2001-02-28 2007-03-13 Nidek Co., Ltd. Built-in-eye eyesight stimulating apparatus
US20090204207A1 (en) * 2007-02-23 2009-08-13 Pixeloptics, Inc. Advanced Electro-Active Optic Device
US20090216295A1 (en) * 2006-04-28 2009-08-27 Eberhart Zrenner Active sub-retina implant
US20100204754A1 (en) * 2009-02-09 2010-08-12 Rainbow Medical Ltd. Retinal prosthesis
US7831309B1 (en) * 2006-12-06 2010-11-09 University Of Southern California Implants based on bipolar metal oxide semiconductor (MOS) electronics
US7853330B2 (en) * 2001-12-04 2010-12-14 Boston Scientific Neuromodulation Corporation Apparatus and method for determining the relative position and orientation of neurostimulation leads

Family Cites Families (252)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1662446A (en) 1924-01-14 1928-03-13 Wappler Electric Company Inc Metal-foil electrode
US2721316A (en) 1953-06-09 1955-10-18 Joseph D Shaw Method and means for aiding the blind
US2760483A (en) 1953-10-29 1956-08-28 Tassicker Graham Edward Retinal stimulator
JPS5429639A (en) * 1977-08-09 1979-03-05 Ricoh Co Ltd Mulistylus electrostatic recording method
US4197850A (en) 1978-11-03 1980-04-15 Pacesetter Systems, Inc. Implantable human tissue stimulator with memory protect means
US4272910A (en) 1979-07-31 1981-06-16 Danz W R Ocular prosthetic or the like
US4324252A (en) 1980-08-04 1982-04-13 Medtronic, Inc. Memory control circuitry for implantable medical devices
US4486861A (en) 1981-12-24 1984-12-04 At&T Technologies, Inc. Transponder telemetry
US4551149A (en) 1982-02-16 1985-11-05 Michael Sciarra Prosthetic vision system
US4601545A (en) 1984-05-16 1986-07-22 Kern Seymour P Variable power lens system
US4664117A (en) 1984-10-09 1987-05-12 Beck Stephen C Apparatus and method for generating phosphenes
US4628933A (en) 1985-07-23 1986-12-16 Michelson Robin P Method and apparatus for visual prosthesis
US4969468A (en) 1986-06-17 1990-11-13 Alfred E. Mann Foundation For Scientific Research Electrode array for use in connection with a living body and method of manufacture
US4837049A (en) 1986-06-17 1989-06-06 Alfred E. Mann Foundation For Scientific Research Method of making an electrode array
JPH0758226B2 (en) 1987-09-10 1995-06-21 富士写真フイルム株式会社 Light source detection device
US4786818A (en) 1987-11-09 1988-11-22 California Institute Of Technology Integrated sensor and processor for visual images
US4903702A (en) 1988-10-17 1990-02-27 Ad-Tech Medical Instrument Corporation Brain-contact for sensing epileptogenic foci with improved accuracy
US5665954A (en) 1988-10-21 1997-09-09 Symbol Technologies, Inc. Electro-optical scanner module having dual electro-magnetic coils
US5159927A (en) 1989-07-26 1992-11-03 Ferdinand Schmid Visual prosthesis apparatus and method
US5016633A (en) 1989-08-08 1991-05-21 Chow Alan Y Artificial retina device
US5024223A (en) 1989-08-08 1991-06-18 Chow Alan Y Artificial retina device
RU1799577C (en) 1989-08-17 1993-03-07 Межотраслевой научно-технический комплекс "Микрохирургия глаза" Method for improving vision function affected by ophthalmic nerve and retina disease
US5215088A (en) 1989-11-07 1993-06-01 The University Of Utah Three-dimensional electrode device
JPH0671186B2 (en) 1990-01-19 1994-09-07 株式会社東芝 Logarithmic amplifier circuit
US5314458A (en) 1990-06-01 1994-05-24 University Of Michigan Single channel microstimulator
US5313642A (en) 1990-10-03 1994-05-17 Seagull Scientific Systems, Inc. Power interface for peripheral devices
US5109844A (en) 1990-10-11 1992-05-05 Duke University Retinal microstimulation
US5108427A (en) 1991-01-07 1992-04-28 Majercik Stephen M Active pupillary prosthesis
US5133356A (en) 1991-04-16 1992-07-28 Minnesota Mining And Manufacturing Company Biomedical electrode having centrally-positioned tab construction
US5526423A (en) 1991-05-08 1996-06-11 Canon Kabushiki Kaisha Communication apparatus and method with service execution according to dial number
DE4209536C3 (en) 1992-03-24 2000-10-05 Stuttgart Mikroelektronik Image cell for an image sensor chip
US5476494A (en) 1992-09-11 1995-12-19 Massachusetts Institute Of Technology Low pressure neural contact structure
US5397350A (en) 1993-05-03 1995-03-14 Chow; Alan Y. Independent photoelectric artificial retina device and method of using same
US5411540A (en) 1993-06-03 1995-05-02 Massachusetts Institute Of Technology Method and apparatus for preferential neuron stimulation
US5597381A (en) 1993-06-03 1997-01-28 Massachusetts Eye And Ear Infirmary Methods for epi-retinal implantation
US5800535A (en) 1994-02-09 1998-09-01 The University Of Iowa Research Foundation Wireless prosthetic electrode for the brain
US5769875A (en) 1994-09-06 1998-06-23 Case Western Reserve University Functional neuromusclar stimulation system
US5834215A (en) 1994-10-05 1998-11-10 The Administrators Of The Tulane Educational Fund Method for detecting antipolymer antibodies and diagnosing silicone related disease (SRD) fibromyalgia and chronic fatigue syndrome (CFS)
JPH08297465A (en) 1995-04-26 1996-11-12 Hiroshi Yamamoto Optic nerve video output device and its method
DE69636151T2 (en) 1995-06-06 2006-09-14 Optobionics Corp., Naperville Arrangement for irritation of the retina by means of adaptive imaging
US5895415A (en) 1995-06-06 1999-04-20 Optobionics Corporation Multi-phasic microphotodiode retinal implant and adaptive imaging retinal stimulation system
US5873901A (en) 1995-06-30 1999-02-23 Space Vacuum Epitaxy Center University Of Houston Treating retinal damage by implanting thin film optical detectors
DE19529371C3 (en) 1995-08-10 2003-05-28 Nmi Univ Tuebingen Microelectrode array
CA2235216C (en) 1995-10-19 2006-05-30 The University Of Melbourne Embedded data link and protocol
JP4036896B2 (en) 1995-12-01 2008-01-23 キネティック リミテッド Imaging system
US5800478A (en) 1996-03-07 1998-09-01 Light Sciences Limited Partnership Flexible microcircuits for internal light therapy
US5800533A (en) 1996-03-18 1998-09-01 Harry C. Eggleston Adjustable intraocular lens implant with magnetic adjustment facilities
JP3633092B2 (en) 1996-03-18 2005-03-30 日産自動車株式会社 Microcomputer failure monitoring device
DE19639644A1 (en) 1996-09-26 1998-04-02 Siemens Ag Method and arrangement for controlling functions in a program-controlled circuit arrangement when the operating voltage fails
DE19705988C2 (en) 1996-10-23 2002-04-11 Univ Eberhard Karls Retinal implant
WO1998017344A1 (en) 1996-10-23 1998-04-30 Eberhard-Karls-Universität Tübingen Universitätsklinikum Optically controllable microelectrode arrangement for stimulating cells, in particular a retina implant
US5837995A (en) 1996-11-25 1998-11-17 Alan Y. Chow Wavelength-controllable voltage-phase photodiode optoelectronic switch ("opsistor")
US5735882A (en) 1996-11-25 1998-04-07 Sulzer Intermedics Inc. Cardiac stimulator with backup-mode self-recovery
US6043437A (en) 1996-12-20 2000-03-28 Alfred E. Mann Foundation Alumina insulation for coating implantable components and other microminiature devices
US5836996A (en) 1996-12-30 1998-11-17 Doorish; John F. Artificial retina
US5865839A (en) 1996-12-30 1999-02-02 Doorish; John F. Artificial retina
DE19707046A1 (en) 1997-02-21 1998-08-27 Rolf Prof Dr Ing Eckmiller Learnable "Active Vision" implant encoder
US6259937B1 (en) 1997-09-12 2001-07-10 Alfred E. Mann Foundation Implantable substrate sensor
DE19741487C2 (en) 1997-09-19 2000-08-31 Univ Eberhard Karls Device for access to the subretinal space of an eye
US6069365A (en) 1997-11-25 2000-05-30 Alan Y. Chow Optical processor based imaging system
AU745407C (en) 1998-03-09 2002-11-07 Oerlikon Contraves Ag Identification system
US5944747A (en) 1998-03-13 1999-08-31 Johns Hopkins University Method for preferential outer retinal stimulation
US5935155A (en) 1998-03-13 1999-08-10 John Hopkins University, School Of Medicine Visual prosthesis and method of using same
US6324429B1 (en) 1998-05-08 2001-11-27 Massachusetts Eye And Ear Infirmary Chronically implantable retinal prosthesis
US6035236A (en) * 1998-07-13 2000-03-07 Bionergy Therapeutics, Inc. Methods and apparatus for electrical microcurrent stimulation therapy
EP1113840A1 (en) 1998-07-27 2001-07-11 J. Thomas Mortimer Device and method for production of visual sensations by optic nerve stimulation
US6165192A (en) 1999-01-05 2000-12-26 Second Sight, Llc Method and apparatus for intraocular retinal tack inserter
DE19911103B4 (en) 1999-03-12 2005-06-16 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Generation of stabilized, ultrashort light pulses and their application for the synthesis of optical frequencies
ATE430596T1 (en) 1999-03-24 2009-05-15 Second Sight Medical Prod Inc RETINAL COLOR PROSTHESIS FOR RESTORING COLOR VISION
US8180453B2 (en) 1999-03-24 2012-05-15 Second Sight Medical Products, Inc. Electrode array for neural stimulation
US6507758B1 (en) 1999-03-24 2003-01-14 Second Sight, Llc Logarithmic light intensifier for use with photoreceptor-based implanted retinal prosthetics and those prosthetics
EP1178763B1 (en) 1999-05-07 2008-12-10 Retina Implant AG Retina implant and method for producing the same
DE19921399C2 (en) 1999-05-07 2003-12-18 Univ Eberhard Karls Retinal implant
JP3685956B2 (en) 1999-06-11 2005-08-24 住友重機械工業株式会社 Eyeball irradiation control device
US6888571B1 (en) 1999-09-27 2005-05-03 Casio Computer Co., Ltd. Photosensor system and drive control method thereof
US6658299B1 (en) 2000-01-04 2003-12-02 William H. Dobelle Artificial system for vision and the like
US6287372B1 (en) 2000-03-31 2001-09-11 Themec Company Incorporated Anti-corrosive coating
US6389317B1 (en) 2000-03-31 2002-05-14 Optobionics Corporation Multi-phasic microphotodetector retinal implant with variable voltage and current capability
US6427087B1 (en) 2000-05-04 2002-07-30 Optobionics Corporation Artificial retina device with stimulating and ground return electrodes disposed on opposite sides of the neuroretina and method of attachment
CN1277589C (en) 2000-05-31 2006-10-04 超治疗股份有限公司 Electropancreatography
US6677225B1 (en) 2000-07-14 2004-01-13 Zyvex Corporation System and method for constraining totally released microcomponents
KR100381890B1 (en) 2000-08-04 2003-04-26 국방과학연구소 Supporting structure of hydrophone for towed array sonar system
US6970745B2 (en) 2000-08-09 2005-11-29 The United States Of America As Represented By The Secretary Of The Navy Microelectronic stimulator array for stimulating nerve tissue
US6647297B2 (en) 2000-08-09 2003-11-11 The United States Of America As Represented By The Secretary Of The Navy Permanent retinal implant device
GB2370509A (en) 2000-08-29 2002-07-03 Don Edward Casey Subcutaneously implanted photovoltaic power supply
ATE336279T1 (en) 2000-11-16 2006-09-15 Polyvalor Sec ELECTRONIC BODY IMPLANT AND ARTIFICIAL VISION SYSTEM
US6368349B1 (en) 2000-11-21 2002-04-09 Massachusetts Institute Of Technology Inflatable neural prosthesis
US6908470B2 (en) 2001-01-11 2005-06-21 Fraunhofer-Gesellschaft Zur Foderung Der Angewandten Forschung E.V. Sieve electrode which can be connected to a nerve stump
US7103416B2 (en) 2001-01-16 2006-09-05 Second Sight Medical Products, Inc. Visual prosthesis including enhanced receiving and stimulating portion
WO2002064029A1 (en) 2001-02-09 2002-08-22 Massachusetts Eye & Ear Infirmary Assessment of retinal function
US7149586B2 (en) 2002-03-28 2006-12-12 Second Sight Medical Products, Inc. Variable pitch electrode array
US8060211B2 (en) 2001-02-13 2011-11-15 Second Sight Medical Products, Inc. Method of reducing retinal stress caused by an implantable retinal electrode array
US7127286B2 (en) 2001-02-28 2006-10-24 Second Sight Medical Products, Inc. Implantable device using ultra-nanocrystalline diamond
US6574022B2 (en) 2001-03-19 2003-06-03 Alan Y. Chow Integral differential optical signal receiver
WO2002080816A1 (en) 2001-03-30 2002-10-17 Nagoya Ind Science Reserach I Electrode member for retinal stimulation, and artificial retinal device using the electrode member
WO2002080828A1 (en) 2001-03-30 2002-10-17 Nidek Co., Ltd. Artificial eye system
US7480988B2 (en) 2001-03-30 2009-01-27 Second Sight Medical Products, Inc. Method and apparatus for providing hermetic electrical feedthrough
US6609840B2 (en) 2001-04-05 2003-08-26 Alan Y. Chow Wave length associative addressing system for WDM type light packet steering
US7037943B2 (en) 2001-04-10 2006-05-02 Optobionics Corporation Retinal treatment method
DE10120083A1 (en) 2001-04-17 2003-01-30 Nmi Univ Tuebingen Pair of measuring electrodes, biosensor with such a pair of measuring electrodes and method of manufacture
DE10120908A1 (en) 2001-04-28 2002-10-31 Td Verwaltungs Gmbh Microcontact structure for implantation in a mammal, especially in a human
AU2002305357A1 (en) 2001-05-01 2002-11-11 Second Sight, Llc High-density array of micro-machined electrodes for neural stimulation
US6766233B2 (en) 2001-05-15 2004-07-20 Intellisist, Llc Modular telematic control unit
US6792314B2 (en) 2001-06-18 2004-09-14 Alfred E. Mann Foundation For Scientific Research Miniature implantable array and stimulation system suitable for eyelid stimulation
US6738672B2 (en) 2001-06-18 2004-05-18 The Alfred E. Mann Foundation For Scientific Research Miniature implantable connectors
US7556621B2 (en) 2001-06-29 2009-07-07 The Board Of Trustees Of The Leland Stanford Junior University Optically controlled microfluidic chip
MXPA03011923A (en) 2001-06-29 2004-03-26 Artificial synapse chip interface for electronic prosthetic retina.
US7031776B2 (en) 2001-06-29 2006-04-18 Optobionics Methods for improving damaged retinal cell function
US7147865B2 (en) 2001-06-29 2006-12-12 The Board Of Trustees Of The Leland Stanford University Artificial synapse chip
US6678458B2 (en) 2001-08-17 2004-01-13 Zynex Corporation System and method for precise positioning of microcomponents
US7295872B2 (en) 2001-10-10 2007-11-13 Massachusetts Institute Of Technology System for and method of power efficient electrical tissue stimulation
US6949763B2 (en) 2001-10-11 2005-09-27 Marc Ovadia Semiconductor and non-semiconductor non-diffusion-governed bioelectrodes
AU2002348971A1 (en) 2001-10-12 2003-04-28 Stefana M. Petrescu Ph-sensitive liposomes for targeted drug delivery
DE10151650A1 (en) 2001-10-17 2003-05-08 Univ Eberhard Karls Electrode arrangement for electrical stimulation of biological material and multi-electrode array for use in such
JP3883126B2 (en) 2001-10-26 2007-02-21 富士通株式会社 Semiconductor integrated circuit device, electronic device incorporating the same, and power consumption reduction method
DE10154700A1 (en) 2001-11-09 2003-05-22 Iip Technologies Gmbh Retinal implant with improved implantation and usage properties
US7146221B2 (en) 2001-11-16 2006-12-05 The Regents Of The University Of California Flexible electrode array for artifical vision
EP1490974A4 (en) 2001-11-30 2006-02-22 Second Sight Medical Prod Inc Floating gate digital-to-analog converter
US6770521B2 (en) 2001-11-30 2004-08-03 Texas Instruments Incorporated Method of making multiple work function gates by implanting metals with metallic alloying additives
US7447479B2 (en) 2001-12-11 2008-11-04 Symbol Technologies, Inc. Dual transceiver module for use with imager and video cameras
US6891549B2 (en) 2002-01-11 2005-05-10 Applied Materials, Inc. System and method for edge enhancement of images
WO2003063242A1 (en) 2002-01-16 2003-07-31 Alfred E. Mann Foundation For Scientific Research Space-saving packaging of electronic circuits
WO2003061537A1 (en) 2002-01-17 2003-07-31 Masachusetts Eye And Ear Infirmary Minimally invasive retinal prosthesis
JP2005519386A (en) 2002-03-05 2005-06-30 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Products and methods for avoiding inaccurate storage of data
US7142909B2 (en) 2002-04-11 2006-11-28 Second Sight Medical Products, Inc. Biocompatible bonding method and electronics package suitable for implantation
US7887681B2 (en) 2002-04-11 2011-02-15 Second Sight Medical Products, Inc. Platinum electrode surface coating and method for manufacturing the same
US6974533B2 (en) 2002-04-11 2005-12-13 Second Sight Medical Products, Inc. Platinum electrode and method for manufacturing the same
US7211103B2 (en) 2002-04-11 2007-05-01 Second Sight Medical Products, Inc. Biocompatible bonding method and electronics package suitable for implantation
US7645262B2 (en) 2002-04-11 2010-01-12 Second Sight Medical Products, Inc. Biocompatible bonding method and electronics package suitable for implantation
EP1499255B1 (en) 2002-04-19 2015-07-22 Syneron Medical Ltd. Handheld transdermal drug delivery and analyte extraction
JP2006508636A (en) 2002-05-08 2006-03-16 ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ Nanotube mat with an array of conduits
US6762116B1 (en) 2002-06-12 2004-07-13 Zyvex Corporation System and method for fabricating microcomponent parts on a substrate having pre-fabricated electronic circuitry thereon
US7158834B2 (en) 2002-06-13 2007-01-02 Atlantic Medical, Inc. Method and apparatus for performing microcurrent stimulation (MSC) therapy
US7400021B2 (en) 2002-06-15 2008-07-15 The University Of Houston System Thin film optical detectors for retinal implantation and methods for making and using same
US6755530B1 (en) 2002-07-16 2004-06-29 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Retinal light processing using carbon nanotubes
US7565202B2 (en) 2002-07-30 2009-07-21 Second Sight Medical Products, Inc. Field focusing and mapping in an electrode array
JP4138407B2 (en) 2002-08-30 2008-08-27 株式会社ニデック Intraocular implant device
US7162308B2 (en) 2002-11-26 2007-01-09 Wilson Greatbatch Technologies, Inc. Nanotube coatings for implantable electrodes
US20040135473A1 (en) 2003-01-15 2004-07-15 Byers Charles L. Piezoelectric devices mounted on integrated circuit chip
US7190051B2 (en) 2003-01-17 2007-03-13 Second Sight Medical Products, Inc. Chip level hermetic and biocompatible electronics package using SOI wafers
US7574263B2 (en) 2003-01-31 2009-08-11 Second Sight Medical Products, Inc. Pixel re-mapping for visual prosthesis
US7047080B2 (en) 2003-02-14 2006-05-16 The Board Of Trustees Of The Leland Stanford Junior University Self-sufficient retinal prosthesis powered by intraocular photovoltaic cells
US7058455B2 (en) 2003-02-14 2006-06-06 The Board Of Trustees Of The Leland Stanford Junior University Interface for making spatially resolved electrical contact to neural cells in a biological neural network
US7447547B2 (en) 2003-02-14 2008-11-04 The Board Of Trustees Of The Leland Stanford Junior University Neural prosthesis based on photomechanical deflectors and tactile sensory cells
WO2004084582A1 (en) 2003-03-17 2004-09-30 Microsound A/S Hearing prosthesis comprising rechargeable battery information
US8014878B2 (en) 2005-04-28 2011-09-06 Second Sight Medical Products, Inc. Flexible circuit electrode array
US8131375B2 (en) 2003-03-21 2012-03-06 Second Sight Medical Products, Inc. Trans-retinal flexible circuit electrode array
DE10315397A1 (en) 2003-04-04 2004-10-14 Carl Zeiss Energy supply device for a retina implant
EP1620166A4 (en) 2003-04-24 2013-01-02 Advanced Neuromodulation Sys Systems and methods for facilitating and/or effectuating development, rehabilitation, restoration, and/or recovery of visual function through neural stimulation
US7127301B1 (en) 2003-04-28 2006-10-24 Sandia Corporation Flexible retinal electrode array
US7035692B1 (en) 2003-04-30 2006-04-25 The Regents Of The University Of California High density polymer-based integrated electrode array
US7571011B2 (en) 2003-05-01 2009-08-04 Second Sight Medical Products, Inc. Adherent metal oxide coating forming a high surface area electrode
US7321796B2 (en) 2003-05-01 2008-01-22 California Institute Of Technology Method and system for training a visual prosthesis
US7096568B1 (en) 2003-07-10 2006-08-29 Zyvex Corporation Method of manufacturing a microcomponent assembly
US7311723B2 (en) 2003-07-11 2007-12-25 University Of Washington Scanning laser device and methods of use
US6821154B1 (en) 2003-10-03 2004-11-23 Alfred E. Mann Foundation For Scientific Research Electrical device connector and method therefor
US6935897B2 (en) 2003-10-03 2005-08-30 Alfred E. Mann Foundation For Scientific Research Electrical device connector and method therefor
CN2650300Y (en) 2003-10-17 2004-10-20 永琨有限公司 Audio-video signal wire
US7338836B2 (en) 2003-11-05 2008-03-04 California Institute Of Technology Method for integrating pre-fabricated chip structures into functional electronic systems
US7766903B2 (en) 2003-12-24 2010-08-03 The Board Of Trustees Of The Leland Stanford Junior University Patterned laser treatment of the retina
US7107097B2 (en) 2004-01-14 2006-09-12 Northstar Neuroscience, Inc. Articulated neural electrode assembly
WO2005072667A1 (en) 2004-01-29 2005-08-11 Konica Minolta Photo Imaging, Inc. Vision auxiliary display unit
AU2005212306B2 (en) 2004-02-06 2010-07-01 Biovisics Medical, Inc. Treatment of vision disorders using electrical, light, and/or sound energy
US7025619B2 (en) 2004-02-13 2006-04-11 Zyvex Corporation Sockets for microassembly
US6923669B1 (en) 2004-02-13 2005-08-02 Zyvex Corporation Microconnectors and non-powered microassembly therewith
US7081630B2 (en) 2004-03-12 2006-07-25 Zyvex Corporation Compact microcolumn for automated assembly
US20060241753A1 (en) 2005-04-25 2006-10-26 Suaning Gregg J Electrode multiplexing method for retinal prosthesis
US8078284B2 (en) 2004-05-25 2011-12-13 Second Sight Medical Products, Inc. Retinal prosthesis with a new configuration
US7263403B2 (en) 2004-05-25 2007-08-28 Second Sight Medical Products, Inc. Retinal prosthesis
JP4458935B2 (en) 2004-06-01 2010-04-28 株式会社ニデック Perimeter
US7483751B2 (en) 2004-06-08 2009-01-27 Second Sight Medical Products, Inc. Automatic fitting for a visual prosthesis
JP4476050B2 (en) 2004-06-30 2010-06-09 株式会社ニデック Perimeter
US7130693B1 (en) 2004-07-07 2006-10-31 National Semiconductor Corporation Method for increasing the resolution and decreasing the power dissipation in eye prosthetics
JP4546184B2 (en) 2004-08-04 2010-09-15 株式会社ニデック Rectification circuit and visual reproduction assisting device having the same
US7494840B2 (en) 2004-10-21 2009-02-24 Sharp Laboratories Of America, Inc. Optical device with IrOx nanostructure electrode neural interface
JP2007042569A (en) 2004-11-16 2007-02-15 Matsushita Electric Ind Co Ltd Signal transmission cable and method of manufacturing the same
US8103352B2 (en) 2004-12-03 2012-01-24 Second Sight Medical Products, Inc. Mimicking neural coding in retinal ganglion cells with short pulse electrical stimulation
US8068913B2 (en) 2004-12-03 2011-11-29 Second Sight Medical Products, Inc. Visual prosthesis for improved circadian rhythms and method of improving the circadian rhythms
US7571004B2 (en) 2005-01-26 2009-08-04 Second Sight Medical Products, Inc. Neural stimulation for increased persistence
EP1858586B1 (en) 2005-02-16 2016-05-11 Second Sight Medical Products, Inc. Fitting of brightness in a visual prosthesis
JP4767571B2 (en) 2005-03-31 2011-09-07 株式会社ニデック Visual reproduction assist device
DE102005017740A1 (en) 2005-04-12 2006-10-19 Universität Tübingen Device for electrical stimulation of biological material
WO2006116625A2 (en) 2005-04-28 2006-11-02 California Institute Of Technology Batch-fabricated flexible intraocular retinal prosthesis systems and methods for manufacturing the same
US8473048B2 (en) 2005-04-28 2013-06-25 Second Sight Medical Products, Inc. Package for an implantable neural stimulation device
EP2932998B1 (en) 2005-04-28 2019-12-25 Second Sight Medical Products, Inc. Flexible circuit electrode array
US8024022B2 (en) 2005-05-25 2011-09-20 Alfred E. Mann Foundation For Scientific Research Hermetically sealed three-dimensional electrode array
US20070005116A1 (en) 2005-06-30 2007-01-04 Lsi Logic Corporation Implantable, fully integrated and high performance semiconductor device for retinal prostheses
EP1743654A1 (en) 2005-07-15 2007-01-17 TopoTarget Germany AG Use of inhibitors of histone deacetylases in combination with NSAID for the therapy of cancer and/or inflammatory diseases
JP4873897B2 (en) 2005-07-29 2012-02-08 株式会社ニデック Visual reproduction assist device
US9913985B2 (en) 2006-04-28 2018-03-13 Second Sight Medical Products, Inc. Method and apparatus to provide safety checks for neural stimulation
WO2007035910A2 (en) 2005-09-19 2007-03-29 Second Sight Medical Products, Inc. Sub-threshold stimulation to precondition neurons for supra-threshold stimulation
US8195266B2 (en) 2005-09-29 2012-06-05 Doheny Eye Institute Microelectrode systems for neuro-stimulation and neuro-sensing and microchip packaging and related methods
US7877866B1 (en) 2005-10-26 2011-02-01 Second Sight Medical Products, Inc. Flexible circuit electrode array and method of manufacturing the same
US20070089992A1 (en) 2005-10-26 2007-04-26 Dao Zhou Electrode surface coating and method for manufacturing the same
EP1949437B2 (en) 2005-11-02 2021-08-04 Second Sight Medical Products, Inc. Implantable microelectronic device and method of manufacture
US8771805B2 (en) 2005-11-10 2014-07-08 Second Sight Medical Products, Inc. Polymer layer comprising silicone and at least one metal trace and a process of manufacturing the same
EP1960040B1 (en) 2005-12-01 2017-02-08 Second Sight Medical Products, Inc. Fitting a neural prosthesis using impedance and electrode height
US7342427B1 (en) 2005-12-19 2008-03-11 National Semiconductor Corporation Automatic clock based power-down circuit
US7610098B2 (en) 2005-12-20 2009-10-27 Imi Intelligent Medical Implants Ag Charge-integrating retinal prosthesis and method
US20110254661A1 (en) 2005-12-23 2011-10-20 Invue Security Products Inc. Programmable security system and method for protecting merchandise
JP2009526461A (en) 2006-02-09 2009-07-16 エヌエックスピー ビー ヴィ Circuit apparatus and method for detecting power down state of voltage supply
US7914842B1 (en) 2006-02-10 2011-03-29 Second Sight Medical Products, Inc Method of manufacturing a flexible circuit electrode array
US8190266B2 (en) 2006-02-15 2012-05-29 Dohey Eye Institute Wide-field retinal prosthesis
JP2007236409A (en) 2006-03-03 2007-09-20 Nidek Co Ltd Visual sense regeneration assisting apparatus
CN100484498C (en) 2006-04-19 2009-05-06 华中科技大学 A flexible retina chip and preparation method thereof
US8271091B2 (en) 2006-04-28 2012-09-18 Second Sight Medical Products, Inc. Visual prosthesis fitting
US8197539B2 (en) 2006-05-05 2012-06-12 University Of Southern California Intraocular camera for retinal prostheses
WO2007146082A2 (en) 2006-06-06 2007-12-21 Second Sight Medical Products, Inc. Molded polymer comprising silicone and at least one metal trace and a process of manufacturing the same
US7750076B2 (en) 2006-06-07 2010-07-06 Second Sight Medical Products, Inc. Polymer comprising silicone and at least one metal trace
AU2007261384B2 (en) 2006-06-19 2011-08-04 Second Sight Medical Products, Inc. Electrode with increased stability and method of manufacturing the same
WO2007149571A2 (en) 2006-06-21 2007-12-27 Second Sight Medical Products, Inc. Flexible circuit electrode array with at least one tack opening
US7388288B2 (en) 2006-07-17 2008-06-17 University Of Utah Research Foundation Flip chip metallization method and devices
WO2008013879A2 (en) 2006-07-26 2008-01-31 Second Sight Medical Products, Inc. Process for cathodic protection of electrode materials
US8548597B2 (en) 2006-09-29 2013-10-01 Second Sight Medical Products, Inc. External coil assembly for implantable medical prostheses
DE102006048819A1 (en) 2006-10-10 2008-04-17 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Device with a basic body
US8239033B2 (en) 2006-10-20 2012-08-07 Second Sight Medical Products, Inc. Visual prosthesis
US8000804B1 (en) 2006-10-27 2011-08-16 Sandia Corporation Electrode array for neural stimulation
US20080114230A1 (en) 2006-11-14 2008-05-15 Bruce Addis Electrode support
US8660660B2 (en) 2006-11-14 2014-02-25 Second Sight Medical Products, Inc. Power scheme for implant stimulators on the human or animal body
US8010202B2 (en) 2006-11-20 2011-08-30 Second Sight Medical Products, Inc. Method of improving electrode tissue interface
US7983308B1 (en) 2006-11-28 2011-07-19 Marvell International Ltd. Method and apparatus for data frame synchronization
JP4731459B2 (en) 2006-12-27 2011-07-27 株式会社ニデック Visual reproduction assist device
US8226661B2 (en) 2007-01-05 2012-07-24 University Of Utah Research Foundation Device and method for manipulating and inserting electrode arrays into neural tissues
US20080234791A1 (en) 2007-01-17 2008-09-25 Jeffrey Edward Arle Spinal cord implant systems and methods
AU2008216010B2 (en) 2007-02-16 2014-01-23 Doheny Eye Institute Flexible circuit electrode array with wire or film support
EP2155327B1 (en) 2007-05-08 2014-07-23 Second Sight Medical Products, Inc. System for providing stimulation inputs to a visual prosthesis implant
US9220169B2 (en) 2007-06-21 2015-12-22 Second Sight Medical Products, Inc. Biocompatible electroplated interconnection electronics package suitable for implantation
US7630771B2 (en) 2007-06-25 2009-12-08 Microtransponder, Inc. Grooved electrode and wireless microtransponder system
EP2192949B1 (en) 2007-07-05 2012-09-05 Second Sight Medical Products, Inc. Return electrode for a flexible circuit electrode array
US8145322B1 (en) 2007-07-19 2012-03-27 Second Sight Medical Products, Inc. Flexible circuit electrode array device and a method for backside processing of a flexible circuit electrode device
TWI337455B (en) 2007-09-12 2011-02-11 Univ Nat Chiao Tung Power controlling apparatus applied to biochip and operating method thereof
WO2009055735A1 (en) 2007-10-24 2009-04-30 Second Sight Medical Products, Inc. Electrode array for even neural pressure having multiple attachment points
US7912556B2 (en) 2008-03-04 2011-03-22 Second Sight Medical Products, Inc. Electrode array for even neural pressure
EP2265171B1 (en) 2008-03-12 2016-03-09 The Trustees of the University of Pennsylvania Flexible and scalable sensor arrays for recording and modulating physiologic activity
EP2364179B1 (en) * 2008-09-18 2015-12-23 Second Sight Medical Products Techniques and functional electrical stimulation to eliminate discomfort during electrical stimulation of the retina
WO2010035173A1 (en) 2008-09-29 2010-04-01 Nxp B.V. Visual prosthesis implant
US8442641B2 (en) 2010-08-06 2013-05-14 Nano-Retina, Inc. Retinal prosthesis techniques
US8428740B2 (en) 2010-08-06 2013-04-23 Nano-Retina, Inc. Retinal prosthesis techniques
US8706243B2 (en) 2009-02-09 2014-04-22 Rainbow Medical Ltd. Retinal prosthesis techniques
US8718784B2 (en) 2010-01-14 2014-05-06 Nano-Retina, Inc. Penetrating electrodes for retinal stimulation
US9444213B2 (en) 2009-03-09 2016-09-13 Nucurrent, Inc. Method for manufacture of multi-layer wire structure for high efficiency wireless communication
WO2010104569A1 (en) 2009-03-09 2010-09-16 Neurds Inc. System and method for wireless power transfer in implantable medical devices
EP2421602B1 (en) 2009-03-27 2016-09-14 Second Sight Medical Products Visual prosthesis fitting system
US20100331733A1 (en) 2009-06-30 2010-12-30 Orthosensor Sensing device and method for an orthopedic joint
EP3685880B1 (en) 2011-01-28 2021-03-24 Stimwave Technologies Incorporated Neural stimulator system
US8939579B2 (en) 2011-01-28 2015-01-27 Light Prescriptions Innovators, Llc Autofocusing eyewear, especially for presbyopia correction
US9079017B2 (en) * 2011-02-15 2015-07-14 University Of Oregon Fractal interconnects for neuro-electronic interfaces and implants using same
US8571669B2 (en) 2011-02-24 2013-10-29 Nano-Retina, Inc. Retinal prosthesis with efficient processing circuits
US8675690B2 (en) 2011-04-19 2014-03-18 Honeywell International Inc. Low latency and self-adjusting frame synchronization algorithm for data streaming applications
KR20120120706A (en) 2011-04-25 2012-11-02 삼성전자주식회사 Auxiliary power supply and user device including auxiliary power supply
GB2496379A (en) 2011-11-04 2013-05-15 Univ Edinburgh A freespace optical communication system which exploits the rolling shutter mechanism of a CMOS camera
JP6362277B2 (en) 2012-06-01 2018-07-25 ブラックベリー リミテッドBlackBerry Limited A universal synchronization engine based on a probabilistic method for lock assurance in multi-format audio systems

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5835250A (en) * 1995-08-23 1998-11-10 Fujitsu Limited Device for driving light emitting element
US6458157B1 (en) * 1997-08-04 2002-10-01 Suaning Gregg Joergen Retinal stimulator
US20040189940A1 (en) * 1999-12-13 2004-09-30 Ernst Kutschbach Method and system for determining the topography for reaction signals of an eye
US7191010B2 (en) * 2001-02-28 2007-03-13 Nidek Co., Ltd. Built-in-eye eyesight stimulating apparatus
US7853330B2 (en) * 2001-12-04 2010-12-14 Boston Scientific Neuromodulation Corporation Apparatus and method for determining the relative position and orientation of neurostimulation leads
US20060184245A1 (en) * 2003-06-23 2006-08-17 Heinz-Gerhard Graf Active retina implant with a multiplicity of pixel elements
US20090216295A1 (en) * 2006-04-28 2009-08-27 Eberhart Zrenner Active sub-retina implant
US7831309B1 (en) * 2006-12-06 2010-11-09 University Of Southern California Implants based on bipolar metal oxide semiconductor (MOS) electronics
US20090204207A1 (en) * 2007-02-23 2009-08-13 Pixeloptics, Inc. Advanced Electro-Active Optic Device
US20100204754A1 (en) * 2009-02-09 2010-08-12 Rainbow Medical Ltd. Retinal prosthesis

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9566191B2 (en) 2009-02-09 2017-02-14 Nano-Retina, Inc. Retinal prosthesis with visible-light filter
US9370417B2 (en) 2013-03-14 2016-06-21 Nano-Retina, Inc. Foveated retinal prosthesis
US9331791B2 (en) 2014-01-21 2016-05-03 Nano Retina Ltd. Transfer of power and data

Also Published As

Publication number Publication date
US9192464B2 (en) 2015-11-24
EP2677962B1 (en) 2019-11-27
US20120221103A1 (en) 2012-08-30
EP2677962A4 (en) 2017-03-15
WO2012114327A2 (en) 2012-08-30
US8571669B2 (en) 2013-10-29
US20140031931A1 (en) 2014-01-30
EP2677962A2 (en) 2014-01-01

Similar Documents

Publication Publication Date Title
WO2012114327A3 (en) Retinal prosthesis with efficient processing circuits
WO2012051433A3 (en) System and method for electrically ablating tissue of a patient
WO2011139623A3 (en) System and method for stimulating sensory nerves
WO2012024441A3 (en) User interface for segmented neurostimulation leads
WO2010105728A3 (en) Active retinal implant
WO2014141089A3 (en) Foveated retinal prosthesis
WO2012139063A3 (en) Stimulation devices and methods
WO2014032030A3 (en) Device and implantation system for electrical stimulation of biological systems
WO2012085907A3 (en) Pacemaker with no production
CA2867351C (en) Systems and methods related to the treatment of back pain
WO2014172693A3 (en) Nasal stimulation devices and methods
WO2014016700A3 (en) Implant sleep apnea treatment device including an antenna
WO2011086545A3 (en) Penetrating electrodes for retinal stimulation
WO2013162708A3 (en) Trial stimulation systems
WO2009097328A3 (en) Fixation of implantable pulse generators
CA2837214C (en) A minimally invasive dermal electroporation device
WO2008106605A3 (en) Method for stimulating retinal response using photoactive devices
WO2013057594A3 (en) Apparatus and method to control an implant
WO2013015563A3 (en) Electro-microneedle integrated body for in-situ cutaneous gene transfer and method of manufacturing same
WO2007124731A3 (en) Stimulation device for osteosynthesis and endoprosthetics
ATE531421T1 (en) ELECTRODE-LEAD CONNECTION WITH POST-IMPLANTATION IMAGING
WO2012021368A3 (en) Medical electrodes
WO2009023543A3 (en) Systems and methods of neuromodulation stimulation for the restoration of sexual function
JP2014514070A5 (en)
WO2008012523A3 (en) Method of powering implanted devices by direct transfer of electrical energy

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12748896

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2012748896

Country of ref document: EP