WO2012032150A3 - Process for obtaining hyaluronic acid of defined molecular weight - Google Patents

Process for obtaining hyaluronic acid of defined molecular weight Download PDF

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Publication number
WO2012032150A3
WO2012032150A3 PCT/EP2011/065632 EP2011065632W WO2012032150A3 WO 2012032150 A3 WO2012032150 A3 WO 2012032150A3 EP 2011065632 W EP2011065632 W EP 2011065632W WO 2012032150 A3 WO2012032150 A3 WO 2012032150A3
Authority
WO
WIPO (PCT)
Prior art keywords
molecular weight
hyaluronic acid
defined molecular
obtaining hyaluronic
obtaining
Prior art date
Application number
PCT/EP2011/065632
Other languages
French (fr)
Other versions
WO2012032150A2 (en
Inventor
Alfredo De Rosa
Antonella D'agostino
Annalisa La Gatta
Chiara Schiraldi
Original Assignee
Altergon S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altergon S.A. filed Critical Altergon S.A.
Publication of WO2012032150A2 publication Critical patent/WO2012032150A2/en
Publication of WO2012032150A3 publication Critical patent/WO2012032150A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

A process is described for obtaining, in an innovative, simple and economical manner, hyaluronic acid and hyaluronans at varying molecular weight.
PCT/EP2011/065632 2010-09-09 2011-09-09 Process for obtaining hyaluronic acid of defined molecular weight WO2012032150A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI2010A001636A IT1401922B1 (en) 2010-09-09 2010-09-09 PROCESS TO OBTAIN DEFINED MOLECULAR WEIGHT HYALURONIC ACID
ITMI2010A001636 2010-09-09

Publications (2)

Publication Number Publication Date
WO2012032150A2 WO2012032150A2 (en) 2012-03-15
WO2012032150A3 true WO2012032150A3 (en) 2012-07-12

Family

ID=43589544

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2011/065632 WO2012032150A2 (en) 2010-09-09 2011-09-09 Process for obtaining hyaluronic acid of defined molecular weight

Country Status (2)

Country Link
IT (1) IT1401922B1 (en)
WO (1) WO2012032150A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111562231B (en) * 2020-06-22 2023-09-15 华熙生物科技股份有限公司 Method for measuring molecular weight of hyaluronic acid

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030119781A1 (en) * 2001-12-21 2003-06-26 Udell Ronald G. Hyaluronic acid in soft gel form
WO2006107330A1 (en) * 2005-04-04 2006-10-12 Advanced Medical Optics, Inc. Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye
WO2009066102A1 (en) * 2007-11-19 2009-05-28 Burdica Biomed Limited Vaginal lubricant comprising hyaluronic acid

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030119781A1 (en) * 2001-12-21 2003-06-26 Udell Ronald G. Hyaluronic acid in soft gel form
WO2006107330A1 (en) * 2005-04-04 2006-10-12 Advanced Medical Optics, Inc. Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye
WO2009066102A1 (en) * 2007-11-19 2009-05-28 Burdica Biomed Limited Vaginal lubricant comprising hyaluronic acid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VILLETTI M A ET AL: "Thermal Degradation of Natural Polymers", JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, KLUWER ACADEMIC PUBLISHERS, DO, vol. 67, no. 2, 1 February 2002 (2002-02-01), pages 295 - 303, XP019254037, ISSN: 1572-8943 *

Also Published As

Publication number Publication date
IT1401922B1 (en) 2013-08-28
ITMI20101636A1 (en) 2012-03-10
WO2012032150A2 (en) 2012-03-15

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