WO2011111070A3 - Novel injectable combination - Google Patents
Novel injectable combination Download PDFInfo
- Publication number
- WO2011111070A3 WO2011111070A3 PCT/IN2011/000159 IN2011000159W WO2011111070A3 WO 2011111070 A3 WO2011111070 A3 WO 2011111070A3 IN 2011000159 W IN2011000159 W IN 2011000159W WO 2011111070 A3 WO2011111070 A3 WO 2011111070A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- combination
- novel injectable
- injectable combination
- formulation
- novel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4152—1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Abstract
Disclosed herein is a stable injectable formulation comprising combination of Citicoline and Edaravone along with Cyclodextrin derivative, useful for the treatment of CNS disorders and ischemic strokes and further discloses a process of preparation of the said formulation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2592/MUM/2009 | 2010-03-09 | ||
IN2592MU2009 | 2010-03-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011111070A2 WO2011111070A2 (en) | 2011-09-15 |
WO2011111070A3 true WO2011111070A3 (en) | 2011-12-22 |
Family
ID=44563942
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2011/000159 WO2011111070A2 (en) | 2010-03-09 | 2011-03-09 | Novel injectable combination |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2011111070A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103006550A (en) * | 2012-12-11 | 2013-04-03 | 哈药集团三精制药股份有限公司 | Citicoline sodium injection and preparation method thereof |
CN103351342B (en) * | 2013-07-03 | 2015-08-05 | 浙江中医药大学 | A kind of Edaravone pharmaceutical co-crystal and preparation method thereof |
CN105012230B (en) * | 2014-04-30 | 2018-01-16 | 长春海悦药业股份有限公司 | A kind of pharmaceutical composition of Edaravone |
CN104490771A (en) * | 2014-12-19 | 2015-04-08 | 成都天台山制药有限公司 | Citicoline Sodium injection pharmaceutical composition and preparation method thereof |
CN110090225B (en) * | 2019-04-19 | 2021-07-16 | 济南康和医药科技有限公司 | Edaravone sodium chloride injection and preparation method thereof |
CN111840220B (en) * | 2020-08-19 | 2022-09-30 | 开封康诺药业有限公司 | Citicoline sodium injection and preparation method thereof |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040142906A1 (en) * | 2001-09-24 | 2004-07-22 | Yanming Wang | Conpositions and method to prevent and treat brain and spinal cord injuries |
US20060264357A1 (en) * | 1997-04-22 | 2006-11-23 | Zikria Bashir A | Capillary membrane stabilization and reduction of tissue injury through use of biodegradable macromolecules with antioxidants and/or other chemicals |
US20080312226A1 (en) * | 2004-11-18 | 2008-12-18 | Takeda Pharmaceutical Company Limited | Amide Compound |
US20090163476A1 (en) * | 2005-03-03 | 2009-06-25 | Sirtris Pharmaceuticals, Inc. | N-Phenyl Benzamide Derivatives as Sirtuin Modulators |
US20090325862A1 (en) * | 2006-05-04 | 2009-12-31 | Christian Steinkuhler | Histone Deacetylase Inhibitors for the Treatment of Neurodegeneration |
-
2011
- 2011-03-09 WO PCT/IN2011/000159 patent/WO2011111070A2/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060264357A1 (en) * | 1997-04-22 | 2006-11-23 | Zikria Bashir A | Capillary membrane stabilization and reduction of tissue injury through use of biodegradable macromolecules with antioxidants and/or other chemicals |
US20040142906A1 (en) * | 2001-09-24 | 2004-07-22 | Yanming Wang | Conpositions and method to prevent and treat brain and spinal cord injuries |
US20080312226A1 (en) * | 2004-11-18 | 2008-12-18 | Takeda Pharmaceutical Company Limited | Amide Compound |
US20090163476A1 (en) * | 2005-03-03 | 2009-06-25 | Sirtris Pharmaceuticals, Inc. | N-Phenyl Benzamide Derivatives as Sirtuin Modulators |
US20090325862A1 (en) * | 2006-05-04 | 2009-12-31 | Christian Steinkuhler | Histone Deacetylase Inhibitors for the Treatment of Neurodegeneration |
Also Published As
Publication number | Publication date |
---|---|
WO2011111070A2 (en) | 2011-09-15 |
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