WO2011049756A3 - Kit for separation of biological fluids - Google Patents

Kit for separation of biological fluids Download PDF

Info

Publication number
WO2011049756A3
WO2011049756A3 PCT/US2010/051892 US2010051892W WO2011049756A3 WO 2011049756 A3 WO2011049756 A3 WO 2011049756A3 US 2010051892 W US2010051892 W US 2010051892W WO 2011049756 A3 WO2011049756 A3 WO 2011049756A3
Authority
WO
WIPO (PCT)
Prior art keywords
kit
piston assembly
biological fluid
separation
biological fluids
Prior art date
Application number
PCT/US2010/051892
Other languages
French (fr)
Other versions
WO2011049756A2 (en
Inventor
Gilad Lavi
Original Assignee
Cytomedix, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2012534244A priority Critical patent/JP5502207B2/en
Priority to EP10825405.3A priority patent/EP2488229B1/en
Application filed by Cytomedix, Inc. filed Critical Cytomedix, Inc.
Priority to CA2775352A priority patent/CA2775352C/en
Priority to CN201080045060.5A priority patent/CN102596284B/en
Priority to DK10825405.3T priority patent/DK2488229T3/en
Priority to NZ599120A priority patent/NZ599120A/en
Priority to MX2012003806A priority patent/MX2012003806A/en
Priority to BR112012007153A priority patent/BR112012007153A2/en
Priority to KR1020127008549A priority patent/KR101626189B1/en
Priority to AU2010308416A priority patent/AU2010308416B2/en
Priority to ES10825405.3T priority patent/ES2448415T3/en
Publication of WO2011049756A2 publication Critical patent/WO2011049756A2/en
Publication of WO2011049756A3 publication Critical patent/WO2011049756A3/en
Priority to IL218727A priority patent/IL218727A0/en
Priority to EG2012040616A priority patent/EG26747A/en
Priority to HK12110697.1A priority patent/HK1169965A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403—Regulation parameters
    • A61M1/341—Regulation parameters by measuring the filtrate rate or volume
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221—Valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150236—Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150244—Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/80—Suction pumps
    • A61M1/81—Piston pumps, e.g. syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/84—Drainage tubes; Aspiration tips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/20—Closure caps or plugs for connectors or open ends of tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/24—Check- or non-return valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/26—Valves closing automatically on disconnecting the line and opening on reconnection thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150229—Pumps for assisting the blood sampling
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0605—Valves, specific forms thereof check valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Abstract

For containing a biological fluid and draining a constituent of the biological fluid, a kit includes a barrel, a piston assembly, a removable element, which is configured to move the piston assembly, a drainage element, which interacts with the piston assembly, and an interacting element, which interacts with the piston assembly. The kit allows for fluid separation without risk of contamination from the biological fluid itself or contamination of the biological fluid itself. Further, the kit offers the advantage of involving no needles or other sharp elements.
PCT/US2010/051892 2009-10-13 2010-10-08 Kit for separation of biological fluids WO2011049756A2 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
KR1020127008549A KR101626189B1 (en) 2009-10-13 2010-10-08 Kit for separation of biological fluids
BR112012007153A BR112012007153A2 (en) 2009-10-13 2010-10-08 biological fluid containment and biological fluid constituent drainage kit
CA2775352A CA2775352C (en) 2009-10-13 2010-10-08 Kit for separation of biological fluids
EP10825405.3A EP2488229B1 (en) 2009-10-13 2010-10-08 Kit for separation of biological fluids
DK10825405.3T DK2488229T3 (en) 2009-10-13 2010-10-08 KIT FOR SEPARATE biological fluids
NZ599120A NZ599120A (en) 2009-10-13 2010-10-08 Kit for separation of biological fluids
AU2010308416A AU2010308416B2 (en) 2009-10-13 2010-10-08 Kit for separation of biological fluids
JP2012534244A JP5502207B2 (en) 2009-10-13 2010-10-08 Body fluid separation kit
CN201080045060.5A CN102596284B (en) 2009-10-13 2010-10-08 Kit for separation of biological fluids
MX2012003806A MX2012003806A (en) 2009-10-13 2010-10-08 Kit for separation of biological fluids.
ES10825405.3T ES2448415T3 (en) 2009-10-13 2010-10-08 Kit for separation of biological fluids
IL218727A IL218727A0 (en) 2009-10-13 2012-03-19 Kit for separation of biological fluids
EG2012040616A EG26747A (en) 2009-10-13 2012-04-03 Kit for separation of biological fluids
HK12110697.1A HK1169965A1 (en) 2009-10-13 2012-10-25 Kit for separation of biological fluids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27260909P 2009-10-13 2009-10-13
US61/272,609 2009-10-13

Publications (2)

Publication Number Publication Date
WO2011049756A2 WO2011049756A2 (en) 2011-04-28
WO2011049756A3 true WO2011049756A3 (en) 2011-09-15

Family

ID=43853973

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/051892 WO2011049756A2 (en) 2009-10-13 2010-10-08 Kit for separation of biological fluids

Country Status (17)

Country Link
US (1) US7927563B1 (en)
EP (1) EP2488229B1 (en)
JP (1) JP5502207B2 (en)
KR (1) KR101626189B1 (en)
CN (1) CN102596284B (en)
AU (1) AU2010308416B2 (en)
BR (1) BR112012007153A2 (en)
CA (1) CA2775352C (en)
DK (1) DK2488229T3 (en)
EG (1) EG26747A (en)
ES (1) ES2448415T3 (en)
HK (1) HK1169965A1 (en)
IL (1) IL218727A0 (en)
MX (1) MX2012003806A (en)
NZ (1) NZ599120A (en)
PE (1) PE20121671A1 (en)
WO (1) WO2011049756A2 (en)

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KR101179548B1 (en) * 2012-03-05 2012-09-05 김준우 Dividing device for blood elements or cell fractions
ES2437541B1 (en) * 2012-07-03 2014-11-25 Biotechnology Institute, I Mas D, S.L. Device for the extraction, storage and / or processing of blood or other substances of human or animal origin, and for the application of blood compounds or other biological compounds
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EP2488229B1 (en) 2013-11-20
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CA2775352A1 (en) 2011-04-28
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PE20121671A1 (en) 2012-12-22
CN102596284A (en) 2012-07-18

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