WO2011041463A3 - Transcutaneous analyte sensor - Google Patents

Transcutaneous analyte sensor Download PDF

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Publication number
WO2011041463A3
WO2011041463A3 PCT/US2010/050788 US2010050788W WO2011041463A3 WO 2011041463 A3 WO2011041463 A3 WO 2011041463A3 US 2010050788 W US2010050788 W US 2010050788W WO 2011041463 A3 WO2011041463 A3 WO 2011041463A3
Authority
WO
WIPO (PCT)
Prior art keywords
host
vivo portion
sensor
skin
sensor body
Prior art date
Application number
PCT/US2010/050788
Other languages
French (fr)
Other versions
WO2011041463A2 (en
Inventor
Paul V. Neale
Robert Boock
Sebastian Bohm
Peter C. Simpson
James Brauker
Original Assignee
Dexcom, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dexcom, Inc. filed Critical Dexcom, Inc.
Priority to EP10821203A priority Critical patent/EP2482724A2/en
Priority to CN2010800438124A priority patent/CN102724913A/en
Publication of WO2011041463A2 publication Critical patent/WO2011041463A2/en
Publication of WO2011041463A3 publication Critical patent/WO2011041463A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6843—Monitoring or controlling sensor contact pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles
    • A61B5/6849—Needles in combination with a needle set
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0443—Modular apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04—Arrangements of multiple sensors of the same type

Abstract

A transcutaneous sensor device configured for continuously measuring analyte concentrations in a host is provided. In some embodiments, the transcutaneous sensor device 100 comprises an in vivo portion 160 configured for insertion under the skin 180 of the host and an ex vivo portion 170 configured to remain above the surface of the skin 180 of the host after sensor insertion of the in vivo portion. The in vivo portion may comprise a tissue piercing element 110 configured for piercing the skin 180 of the host and a sensor body 120 comprising a material or support member 130 that provides sufficient column strength to allow the sensor body to be pushable in a host tissue without substantial buckling. The ex vivo portion 170 may be configured to comprise (or operably connect to) a sensor electronics unit and may comprise a mounting unit 150. Also described here are various configurations of the sensor body and the tissue piercing element that may be used to protect the membrane of the sensor body.
PCT/US2010/050788 2009-09-30 2010-09-29 Transcutaneous analyte sensor WO2011041463A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP10821203A EP2482724A2 (en) 2009-09-30 2010-09-29 Transcutaneous analyte sensor
CN2010800438124A CN102724913A (en) 2009-09-30 2010-09-29 Transcutaneous analyte sensor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24746309P 2009-09-30 2009-09-30
US61/247,463 2009-09-30

Publications (2)

Publication Number Publication Date
WO2011041463A2 WO2011041463A2 (en) 2011-04-07
WO2011041463A3 true WO2011041463A3 (en) 2011-07-14

Family

ID=43781096

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/050788 WO2011041463A2 (en) 2009-09-30 2010-09-29 Transcutaneous analyte sensor

Country Status (4)

Country Link
US (4) US9357951B2 (en)
EP (1) EP2482724A2 (en)
CN (1) CN102724913A (en)
WO (1) WO2011041463A2 (en)

Families Citing this family (210)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
USD914881S1 (en) 2003-11-05 2021-03-30 Abbott Diabetes Care Inc. Analyte sensor electronic mount
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US8545403B2 (en) 2005-12-28 2013-10-01 Abbott Diabetes Care Inc. Medical device insertion
US20090105569A1 (en) 2006-04-28 2009-04-23 Abbott Diabetes Care, Inc. Introducer Assembly and Methods of Use
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8571624B2 (en) * 2004-12-29 2013-10-29 Abbott Diabetes Care Inc. Method and apparatus for mounting a data transmission device in a communication system
US7883464B2 (en) 2005-09-30 2011-02-08 Abbott Diabetes Care Inc. Integrated transmitter unit and sensor introducer mechanism and methods of use
US9572534B2 (en) 2010-06-29 2017-02-21 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
US8029441B2 (en) 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US8333714B2 (en) 2006-09-10 2012-12-18 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US9351669B2 (en) 2009-09-30 2016-05-31 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US9636450B2 (en) 2007-02-19 2017-05-02 Udo Hoss Pump system modular components for delivering medication and analyte sensing at seperate insertion sites
US9259175B2 (en) 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US8512243B2 (en) 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US7731657B2 (en) 2005-08-30 2010-06-08 Abbott Diabetes Care Inc. Analyte sensor introducer and methods of use
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US9743862B2 (en) 2011-03-31 2017-08-29 Abbott Diabetes Care Inc. Systems and methods for transcutaneously implanting medical devices
JP2009507224A (en) 2005-08-31 2009-02-19 ユニヴァーシティー オブ ヴァージニア パテント ファンデーション Improving the accuracy of continuous glucose sensors
US9521968B2 (en) 2005-09-30 2016-12-20 Abbott Diabetes Care Inc. Analyte sensor retention mechanism and methods of use
US8880138B2 (en) * 2005-09-30 2014-11-04 Abbott Diabetes Care Inc. Device for channeling fluid and methods of use
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US7736310B2 (en) 2006-01-30 2010-06-15 Abbott Diabetes Care Inc. On-body medical device securement
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US7981034B2 (en) 2006-02-28 2011-07-19 Abbott Diabetes Care Inc. Smart messages and alerts for an infusion delivery and management system
US7826879B2 (en) 2006-02-28 2010-11-02 Abbott Diabetes Care Inc. Analyte sensors and methods of use
US8346335B2 (en) 2008-03-28 2013-01-01 Abbott Diabetes Care Inc. Analyte sensor calibration management
US8473022B2 (en) 2008-01-31 2013-06-25 Abbott Diabetes Care Inc. Analyte sensor with time lag compensation
US7653425B2 (en) 2006-08-09 2010-01-26 Abbott Diabetes Care Inc. Method and system for providing calibration of an analyte sensor in an analyte monitoring system
US9339217B2 (en) 2011-11-25 2016-05-17 Abbott Diabetes Care Inc. Analyte monitoring system and methods of use
US9392969B2 (en) 2008-08-31 2016-07-19 Abbott Diabetes Care Inc. Closed loop control and signal attenuation detection
US9675290B2 (en) 2012-10-30 2017-06-13 Abbott Diabetes Care Inc. Sensitivity calibration of in vivo sensors used to measure analyte concentration
US9326709B2 (en) 2010-03-10 2016-05-03 Abbott Diabetes Care Inc. Systems, devices and methods for managing glucose levels
US8374668B1 (en) 2007-10-23 2013-02-12 Abbott Diabetes Care Inc. Analyte sensor with lag compensation
US8478557B2 (en) 2009-07-31 2013-07-02 Abbott Diabetes Care Inc. Method and apparatus for providing analyte monitoring system calibration accuracy
US8140312B2 (en) 2007-05-14 2012-03-20 Abbott Diabetes Care Inc. Method and system for determining analyte levels
US8219173B2 (en) 2008-09-30 2012-07-10 Abbott Diabetes Care Inc. Optimizing analyte sensor calibration
US7630748B2 (en) 2006-10-25 2009-12-08 Abbott Diabetes Care Inc. Method and system for providing analyte monitoring
US8224415B2 (en) 2009-01-29 2012-07-17 Abbott Diabetes Care Inc. Method and device for providing offset model based calibration for analyte sensor
US7618369B2 (en) 2006-10-02 2009-11-17 Abbott Diabetes Care Inc. Method and system for dynamically updating calibration parameters for an analyte sensor
US8932216B2 (en) 2006-08-07 2015-01-13 Abbott Diabetes Care Inc. Method and system for providing data management in integrated analyte monitoring and infusion system
US8206296B2 (en) 2006-08-07 2012-06-26 Abbott Diabetes Care Inc. Method and system for providing integrated analyte monitoring and infusion system therapy management
CN101636104B (en) 2006-10-26 2012-07-18 雅培糖尿病护理公司 Method, system for real-time detection of sensitivity decline in analyte sensors
US8930203B2 (en) * 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
EP2146623B1 (en) 2007-04-14 2014-01-08 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
CA2683962C (en) 2007-04-14 2017-06-06 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
ES2817503T3 (en) 2007-04-14 2021-04-07 Abbott Diabetes Care Inc Procedure and apparatus for providing data processing and control in a medical communication system
EP2146624B1 (en) 2007-04-14 2020-03-25 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in medical communication system
US8600681B2 (en) 2007-05-14 2013-12-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US10002233B2 (en) 2007-05-14 2018-06-19 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8260558B2 (en) 2007-05-14 2012-09-04 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8103471B2 (en) 2007-05-14 2012-01-24 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8560038B2 (en) 2007-05-14 2013-10-15 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US9125548B2 (en) 2007-05-14 2015-09-08 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8444560B2 (en) 2007-05-14 2013-05-21 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8239166B2 (en) 2007-05-14 2012-08-07 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
WO2008150917A1 (en) * 2007-05-31 2008-12-11 Abbott Diabetes Care, Inc. Insertion devices and methods
US8160900B2 (en) 2007-06-29 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring and management device and method to analyze the frequency of user interaction with the device
US8834366B2 (en) 2007-07-31 2014-09-16 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor calibration
US20090063402A1 (en) * 2007-08-31 2009-03-05 Abbott Diabetes Care, Inc. Method and System for Providing Medication Level Determination
US8409093B2 (en) 2007-10-23 2013-04-02 Abbott Diabetes Care Inc. Assessing measures of glycemic variability
US8377031B2 (en) 2007-10-23 2013-02-19 Abbott Diabetes Care Inc. Closed loop control system with safety parameters and methods
US20090164239A1 (en) 2007-12-19 2009-06-25 Abbott Diabetes Care, Inc. Dynamic Display Of Glucose Information
US8924159B2 (en) 2008-05-30 2014-12-30 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
US8591410B2 (en) 2008-05-30 2013-11-26 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
US8876755B2 (en) 2008-07-14 2014-11-04 Abbott Diabetes Care Inc. Closed loop control system interface and methods
US20100057040A1 (en) 2008-08-31 2010-03-04 Abbott Diabetes Care, Inc. Robust Closed Loop Control And Methods
US8734422B2 (en) 2008-08-31 2014-05-27 Abbott Diabetes Care Inc. Closed loop control with improved alarm functions
US8622988B2 (en) * 2008-08-31 2014-01-07 Abbott Diabetes Care Inc. Variable rate closed loop control and methods
US9943644B2 (en) 2008-08-31 2018-04-17 Abbott Diabetes Care Inc. Closed loop control with reference measurement and methods thereof
US8986208B2 (en) 2008-09-30 2015-03-24 Abbott Diabetes Care Inc. Analyte sensor sensitivity attenuation mitigation
US9326707B2 (en) 2008-11-10 2016-05-03 Abbott Diabetes Care Inc. Alarm characterization for analyte monitoring devices and systems
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US9402544B2 (en) 2009-02-03 2016-08-02 Abbott Diabetes Care Inc. Analyte sensor and apparatus for insertion of the sensor
US9339229B2 (en) 2009-02-26 2016-05-17 Abbott Diabetes Care Inc. Analyte monitoring devices and methods
US8497777B2 (en) 2009-04-15 2013-07-30 Abbott Diabetes Care Inc. Analyte monitoring system having an alert
EP2419015A4 (en) * 2009-04-16 2014-08-20 Abbott Diabetes Care Inc Analyte sensor calibration management
WO2010127051A1 (en) 2009-04-29 2010-11-04 Abbott Diabetes Care Inc. Method and system for providing real time analyte sensor calibration with retrospective backfill
US9795326B2 (en) 2009-07-23 2017-10-24 Abbott Diabetes Care Inc. Continuous analyte measurement systems and systems and methods for implanting them
EP4276652A3 (en) 2009-07-23 2024-01-31 Abbott Diabetes Care, Inc. Real time management of data relating to physiological control of glucose levels
EP2473963A4 (en) 2009-08-31 2014-01-08 Abbott Diabetes Care Inc Medical devices and methods
EP4070729A1 (en) 2009-08-31 2022-10-12 Abbott Diabetes Care, Inc. Displays for a medical device
US9320461B2 (en) 2009-09-29 2016-04-26 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
CN102724913A (en) 2009-09-30 2012-10-10 德克斯康公司 Transcutaneous analyte sensor
US8185181B2 (en) 2009-10-30 2012-05-22 Abbott Diabetes Care Inc. Method and apparatus for detecting false hypoglycemic conditions
US8660628B2 (en) * 2009-12-21 2014-02-25 Medtronic Minimed, Inc. Analyte sensors comprising blended membrane compositions and methods for making and using them
US9370322B2 (en) * 2009-12-31 2016-06-21 Medtronic Minimed, Inc. Modular docking station
USD924406S1 (en) 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
EP2549918B2 (en) 2010-03-24 2023-01-25 Abbott Diabetes Care, Inc. Medical device inserters and processes of inserting and using medical devices
US8635046B2 (en) 2010-06-23 2014-01-21 Abbott Diabetes Care Inc. Method and system for evaluating analyte sensor response characteristics
US10092229B2 (en) 2010-06-29 2018-10-09 Abbott Diabetes Care Inc. Calibration of analyte measurement system
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
AU2011282711A1 (en) 2010-07-28 2013-01-10 Abbott Diabetes Care Inc. Analyte sensors having temperature independent membranes
WO2012048168A2 (en) 2010-10-07 2012-04-12 Abbott Diabetes Care Inc. Analyte monitoring devices and methods
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
DK3575796T3 (en) 2011-04-15 2021-01-18 Dexcom Inc ADVANCED ANALYZE SENSOR CALIBRATION AND ERROR DETECTION
WO2012174538A1 (en) 2011-06-17 2012-12-20 Abbott Diabetes Care Inc. Connectors for making connections between analyte sensors and other devices
KR101542549B1 (en) 2011-09-02 2015-08-06 산디아 코포레이션 Microneedle arrays for biosensing and drug delivery
US9439602B2 (en) * 2011-10-26 2016-09-13 Dexcom, Inc. Alert system for hypo and hyperglycemia prevention based on clinical risk
WO2013066849A1 (en) 2011-10-31 2013-05-10 Abbott Diabetes Care Inc. Model based variable risk false glucose threshold alarm prevention mechanism
US8710993B2 (en) 2011-11-23 2014-04-29 Abbott Diabetes Care Inc. Mitigating single point failure of devices in an analyte monitoring system and methods thereof
US9317656B2 (en) 2011-11-23 2016-04-19 Abbott Diabetes Care Inc. Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof
EP4056105B1 (en) 2011-12-11 2023-10-11 Abbott Diabetes Care, Inc. Analyte sensor devices
US20130178726A1 (en) * 2012-01-05 2013-07-11 Medtronic Minimed, Inc. Stabilized polymers for use with analyte sensors and methods for making and using them
US20130197468A1 (en) * 2012-01-26 2013-08-01 Carnegie Mellon University Device for Intramyocardial Delivery
US9931065B2 (en) 2012-04-04 2018-04-03 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
US10453573B2 (en) 2012-06-05 2019-10-22 Dexcom, Inc. Dynamic report building
BR112014032559A2 (en) * 2012-06-25 2017-06-27 Bioengineering Laboratories Llc enzyme electrode
US10881339B2 (en) 2012-06-29 2021-01-05 Dexcom, Inc. Use of sensor redundancy to detect sensor failures
US10598627B2 (en) 2012-06-29 2020-03-24 Dexcom, Inc. Devices, systems, and methods to compensate for effects of temperature on implantable sensors
US20140012511A1 (en) 2012-07-09 2014-01-09 Dexcom, Inc. Systems and methods for leveraging smartphone features in continuous glucose monitoring
EP2890297B1 (en) 2012-08-30 2018-04-11 Abbott Diabetes Care, Inc. Dropout detection in continuous analyte monitoring data during data excursions
WO2014052136A1 (en) 2012-09-26 2014-04-03 Abbott Diabetes Care Inc. Method and apparatus for improving lag correction during in vivo measurement of analyte concentration with analyte concentration variability and range data
US9788765B2 (en) 2012-09-28 2017-10-17 Dexcom, Inc. Zwitterion surface modifications for continuous sensors
US20140107450A1 (en) * 2012-10-12 2014-04-17 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
US20140213866A1 (en) * 2012-10-12 2014-07-31 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
US20140129151A1 (en) 2012-11-07 2014-05-08 Dexcom, Inc. Systems and methods for managing glycemic variability
EP2934659B1 (en) * 2012-12-21 2019-03-06 3M Innovative Properties Company Adhesive assemblies and microneedle injection apparatuses comprising same
US9730621B2 (en) 2012-12-31 2017-08-15 Dexcom, Inc. Remote monitoring of analyte measurements
US9585563B2 (en) * 2012-12-31 2017-03-07 Dexcom, Inc. Remote monitoring of analyte measurements
US9788354B2 (en) 2013-03-14 2017-10-10 Dexcom, Inc. Systems and methods for processing and transmitting sensor data
EP4235684A1 (en) 2013-03-14 2023-08-30 Dexcom, Inc. Systems and methods for processing and transmitting sensor data
JP6514186B2 (en) * 2013-03-14 2019-05-15 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ Continuous glucose monitor surface sensor
US9182368B2 (en) 2013-03-14 2015-11-10 Sano Intelligence, Inc. Method of manufacturing a sensor for sensing analytes
US10335075B2 (en) 2013-03-14 2019-07-02 Dexcom, Inc. Advanced calibration for analyte sensors
US10820860B2 (en) 2013-03-14 2020-11-03 One Drop Biosensor Technologies, Llc On-body microsensor for biomonitoring
MX2015012860A (en) * 2013-03-14 2016-02-05 Church & Dwight Co Inc Diagnostic test device with improved display.
US9737250B2 (en) 2013-03-15 2017-08-22 Dexcom, Inc. Membrane for continuous analyte sensors
US10076285B2 (en) 2013-03-15 2018-09-18 Abbott Diabetes Care Inc. Sensor fault detection using analyte sensor data pattern comparison
US9474475B1 (en) 2013-03-15 2016-10-25 Abbott Diabetes Care Inc. Multi-rate analyte sensor data collection with sample rate configurable signal processing
US10433773B1 (en) 2013-03-15 2019-10-08 Abbott Diabetes Care Inc. Noise rejection methods and apparatus for sparsely sampled analyte sensor data
FI20135852A (en) * 2013-08-21 2015-03-06 Modz Oy Apparatus and systems for measuring and presenting the glucose level in the blood
CN105530867B (en) * 2013-08-21 2018-11-13 传感技术股份有限公司 The medicament elution protected in vivo for biological sensing analyte
US9770207B2 (en) 2013-12-23 2017-09-26 Verily Life Sciences Llc Sensor electrodes in a bio-compatible device
US9500616B2 (en) 2013-12-23 2016-11-22 Cilag Gmbh International Multi-orientation test strip
CN105899132B (en) 2013-12-31 2020-02-18 雅培糖尿病护理公司 Self-powered analyte sensor and devices using same
WO2015122964A1 (en) 2014-02-11 2015-08-20 Dexcom, Inc. Packaging system for analyte sensors
US10595754B2 (en) 2014-03-13 2020-03-24 Sano Intelligence, Inc. System for monitoring body chemistry
CN106102578A (en) 2014-03-13 2016-11-09 萨诺智能公司 For monitoring the system of body chemistry
EP3865063A1 (en) 2014-03-30 2021-08-18 Abbott Diabetes Care, Inc. Method and apparatus for determining meal start and peak events in analyte monitoring systems
US20150289788A1 (en) * 2014-04-10 2015-10-15 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
FI3128902T3 (en) * 2014-04-10 2023-11-16 Dexcom Inc Sensor for continuous analyte monitoring
US9936883B2 (en) * 2014-07-21 2018-04-10 Sumeet Vadera Temporary or long term implantation device for intracranial probes having hematoma detection apparatus, and method of using device thereof
US9729193B2 (en) * 2014-11-11 2017-08-08 Ut-Battelle, Llc Wireless sensor platform
EP3258848B1 (en) * 2015-02-16 2021-05-12 Verily Life Sciences LLC Electrochemical sensor for a bandage type of continuous glucose monitoring system
US10251605B2 (en) 2015-02-16 2019-04-09 Verily Life Sciences Llc Bandage type of continuous glucose monitoring system
DE102015104583A1 (en) * 2015-03-26 2016-09-29 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Implantable device for forming a permanent skin passage
AU2016258193A1 (en) 2015-05-07 2017-08-17 Dexcom, Inc. System and method for educating users, including responding to patterns
WO2016182315A1 (en) * 2015-05-11 2016-11-17 Samsung Electronics Co., Ltd. Biosensor electrode structure and biosensor including the same
KR20160132750A (en) * 2015-05-11 2016-11-21 삼성전자주식회사 Electrode structure of biosenor and biosnesor comprising that
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
CA2984939A1 (en) 2015-05-14 2016-11-17 Abbott Diabetes Care Inc. Compact medical device inserters and related systems and methods
EP3297708B1 (en) 2015-05-22 2022-02-23 DexCom, Inc. Needle for transcutaneous analyte sensor delivery
US10292630B2 (en) * 2015-06-01 2019-05-21 Verily Life Sciences Llc Optical sensor for bandage type monitoring device
US10765353B2 (en) * 2015-07-02 2020-09-08 Verily Life Sciences Llc Calibration methods for a bandage-type analyte sensor
JP6986007B2 (en) 2015-07-10 2021-12-22 アボット ダイアベティス ケア インコーポレイテッドAbbott Diabetes Care Inc. Systems, devices and methods of dynamic glucose profile response to physiological parameters
WO2017040174A1 (en) 2015-09-04 2017-03-09 Ut-Battelle, Llc Direct write sensors
CN108348174B (en) * 2015-10-19 2020-12-25 柯惠有限合伙公司 System and method for providing blood pressure safety zone indication during autoregulation monitoring
US20170112533A1 (en) * 2015-10-21 2017-04-27 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
JP2017108763A (en) * 2015-12-14 2017-06-22 セイコーエプソン株式会社 Electrode needle, biological information measurement device, and liquid supply device
WO2017116692A1 (en) 2015-12-28 2017-07-06 Dexcom, Inc. Systems and methods for remote and host monitoring communications
CA3002099A1 (en) * 2015-12-30 2017-07-06 Dexcom, Inc. Diffusion resistance layer for analyte sensors
US20170188911A1 (en) 2015-12-30 2017-07-06 Dexcom, Inc. Transcutaneous analyte sensor systems and methods
AU2017245131B2 (en) 2016-03-31 2020-01-30 Dexcom, Inc. Systems and methods for display device and sensor electronics unit communication
US11298059B2 (en) 2016-05-13 2022-04-12 PercuSense, Inc. Analyte sensor
BR112018072336A8 (en) 2016-06-22 2023-03-14 Hoffmann La Roche MEDICAL DEVICE, ANALYTE MEASUREMENT DEVICE, MEDICATION DEVICE AND METHOD FOR TRANSCUTANEOUS INSERTION OF AN INSERABLE ELEMENT
US11032855B2 (en) 2016-10-18 2021-06-08 Dexcom, Inc. System and method for communication of analyte data
EP3915475A1 (en) * 2016-10-18 2021-12-01 Dexcom, Inc. System and method for communication of analyte data
KR20180043612A (en) 2016-10-20 2018-04-30 삼성전자주식회사 Electronic Apparatus and Controlling Method thereof
AU2017347902B2 (en) * 2016-10-31 2023-02-23 Dexcom, Inc. Transcutaneous analyte sensor systems and methods
US10827958B2 (en) * 2016-11-29 2020-11-10 Dexcom, Inc. Sensor holder device for invasive biosensors
AU2017388066B9 (en) * 2016-12-27 2021-04-01 Dexcom, Inc. Systems and methods for patient monitoring using an HCP - specific device
CN110418605A (en) * 2017-01-19 2019-11-05 德克斯康公司 Flexible analyte sensor
CN110461217B (en) 2017-01-23 2022-09-16 雅培糖尿病护理公司 Systems, devices, and methods for analyte sensor insertion
EP3600014A4 (en) 2017-03-21 2020-10-21 Abbott Diabetes Care Inc. Methods, devices and system for providing diabetic condition diagnosis and therapy
ES2905929T3 (en) 2017-05-23 2022-04-12 Hoffmann La Roche Sensor system and procedure for its manufacture
US11653859B2 (en) 2017-06-19 2023-05-23 Dexcom, Inc. Applicators for applying transcutaneous analyte sensors and associated methods of manufacture
HUE063121T2 (en) 2017-06-23 2024-01-28 Dexcom Inc Transcutaneous analyte sensors, applicators therefor, and needle hub comprising anti-rotation feature
US10874300B2 (en) * 2017-09-26 2020-12-29 Medtronic Minimed, Inc. Waferscale physiological characteristic sensor package with integrated wireless transmitter
US20190090743A1 (en) * 2017-09-26 2019-03-28 Medtronic Minimed, Inc. Manufacturing process for fabrication of a waferscale physiological characteristic sensor package
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
CN209606445U (en) 2017-10-24 2019-11-08 德克斯康公司 Pre-connection analyte sensor
US11730403B2 (en) * 2018-02-06 2023-08-22 Arnold Chase Diversified glucose sensor system
USD888252S1 (en) 2018-06-18 2020-06-23 Dexcom, Inc. Transcutaneous analyte sensor applicator
TWI682766B (en) 2018-07-27 2020-01-21 華廣生技股份有限公司 Elastic physiological patch
KR102200142B1 (en) * 2018-09-27 2021-01-11 주식회사 아이센스 Sensor unit for continuous glucose monitoring system
KR102200141B1 (en) * 2018-09-27 2021-01-11 주식회사 아이센스 Sensor unit for continuous glucose monitoring system
WO2020117788A1 (en) * 2018-12-03 2020-06-11 Laxml Therapeutic Devices, Inc. Needles for measurement of body fluid analytes such as glucose
USD1002852S1 (en) 2019-06-06 2023-10-24 Abbott Diabetes Care Inc. Analyte sensor device
CN110144569A (en) * 2019-07-03 2019-08-20 东莞市和域战士纳米科技有限公司 The preparation method of long-acting hydrophilic film
US20220257266A1 (en) * 2019-07-16 2022-08-18 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Automated cranial burr hole device and method
US11737689B2 (en) 2019-08-02 2023-08-29 Bionime Corporation Physiological signal monitoring device
CN112294299A (en) * 2019-08-02 2021-02-02 华广生技股份有限公司 Biosensor implanting device and implanting method thereof
US20210088496A1 (en) * 2019-09-19 2021-03-25 Matthew Hummer System and method for measuring chemicals, analytes and other factors in food
WO2021062378A1 (en) * 2019-09-27 2021-04-01 Duke University In vivo and point-of-care sample capture and testing systems
CN110772214B (en) * 2019-11-06 2021-09-07 西安交通大学第二附属医院 Thoracic surgery endoscope system
AU2021269062A1 (en) * 2020-05-08 2023-01-05 W. L. Gore & Associates, Inc. Transcutaneous sound sensor
US20230219889A1 (en) 2020-05-19 2023-07-13 Cybin Irl Limited Deuterated tryptamine derivatives and methods of use
WO2022026764A1 (en) * 2020-07-29 2022-02-03 Biolinq Inc. Continuous analyte monitoring system with microneedle array
FR3117766A1 (en) * 2020-12-21 2022-06-24 Pkvitality BODY MONITORING DEVICE WITH EXTENDED DETECTION RANGE
USD999913S1 (en) 2020-12-21 2023-09-26 Abbott Diabetes Care Inc Analyte sensor inserter
JP2024504677A (en) * 2021-01-21 2024-02-01 アセンシア・ダイアベティス・ケア・ホールディングス・アーゲー Wearable continuous analyte measurement device, biosensor inserter, and method of use
WO2022182342A1 (en) * 2021-02-25 2022-09-01 Nova Biomedical Corporation Single-use disposable oxygen sensor
USD988882S1 (en) 2021-04-21 2023-06-13 Informed Data Systems Inc. Sensor assembly
SE545874C2 (en) 2021-05-08 2024-02-27 Biolinq Incorporated Fault detection for microneedle array based continuous analyte monitoring device
WO2023034542A1 (en) 2021-09-01 2023-03-09 Integrated Medical Sensors, Inc. Wired implantable monolithic integrated sensor circuit
WO2023044347A1 (en) * 2021-09-14 2023-03-23 Goode Paul V Methods and systems for continuously monitoring the glucose level of a patient
US11654270B2 (en) 2021-09-28 2023-05-23 Biolinq Incorporated Microneedle enclosure and applicator device for microneedle array based continuous analyte monitoring device

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807375A (en) * 1994-11-04 1998-09-15 Elan Medical Technologies Limited Analyte-controlled liquid delivery device and analyte monitor
US20070129619A1 (en) * 2003-06-16 2007-06-07 Isense Corporation Compound material analyte sensor
US20080033269A1 (en) * 2004-12-08 2008-02-07 San Medi Tech (Huzhou) Co., Ltd. Catheter-free implantable needle biosensor

Family Cites Families (169)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0098592A3 (en) 1982-07-06 1985-08-21 Fujisawa Pharmaceutical Co., Ltd. Portable artificial pancreas
DE3379589D1 (en) 1982-10-25 1989-05-18 Hellgren Lars G I Enzyme composition for cleaning, the use thereof and preparation of the composition
CA1226036A (en) 1983-05-05 1987-08-25 Irving J. Higgins Analytical equipment and sensor electrodes therefor
US4671288A (en) * 1985-06-13 1987-06-09 The Regents Of The University Of California Electrochemical cell sensor for continuous short-term use in tissues and blood
US4854322A (en) * 1987-02-25 1989-08-08 Ash Medical Systems, Inc. Capillary filtration and collection device for long-term monitoring of blood constituents
US4777953A (en) 1987-02-25 1988-10-18 Ash Medical Systems, Inc. Capillary filtration and collection method for long-term monitoring of blood constituents
US4832034A (en) * 1987-04-09 1989-05-23 Pizziconi Vincent B Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids
NL8702370A (en) 1987-10-05 1989-05-01 Groningen Science Park METHOD AND SYSTEM FOR GLUCOSE DETERMINATION AND USEABLE MEASURING CELL ASSEMBLY.
GB8725936D0 (en) 1987-11-05 1987-12-09 Genetics Int Inc Sensing system
WO1990007575A1 (en) 1988-12-30 1990-07-12 Anderson David M Stabilized microporous materials and hydrogel materials
DK115989D0 (en) 1989-03-09 1989-03-09 Nordisk Gentofte METHOD AND METHOD FOR MEASURING A LIQUID COMPONENT
US5269891A (en) 1989-03-09 1993-12-14 Novo Nordisk A/S Method and apparatus for determination of a constituent in a fluid
US4953552A (en) 1989-04-21 1990-09-04 Demarzo Arthur P Blood glucose monitoring system
US5324519A (en) 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
US5050612A (en) 1989-09-12 1991-09-24 Matsumura Kenneth N Device for computer-assisted monitoring of the body
US5109850A (en) * 1990-02-09 1992-05-05 Massachusetts Institute Of Technology Automatic blood monitoring for medication delivery method and apparatus
US5165407A (en) 1990-04-19 1992-11-24 The University Of Kansas Implantable glucose sensor
EP0512122A4 (en) 1990-11-22 1993-04-28 Toray Industries, Inc. Implant material
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
US6256522B1 (en) * 1992-11-23 2001-07-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Sensors for continuous monitoring of biochemicals and related method
US5299571A (en) * 1993-01-22 1994-04-05 Eli Lilly And Company Apparatus and method for implantation of sensors
US5582184A (en) 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5390671A (en) * 1994-03-15 1995-02-21 Minimed Inc. Transcutaneous sensor insertion set
US5391250A (en) * 1994-03-15 1995-02-21 Minimed Inc. Method of fabricating thin film sensors
US5569186A (en) * 1994-04-25 1996-10-29 Minimed Inc. Closed loop infusion pump system with removable glucose sensor
CN1157560A (en) 1994-07-08 1997-08-20 巴克斯特国际有限公司 Implanted device containing tumor cells for treatment of cancer
CA2159052C (en) * 1994-10-28 2007-03-06 Rainer Alex Injection device
US5568806A (en) 1995-02-16 1996-10-29 Minimed Inc. Transcutaneous sensor insertion set
US5995860A (en) 1995-07-06 1999-11-30 Thomas Jefferson University Implantable sensor and system for measurement and control of blood constituent levels
DE69630226T2 (en) 1995-07-12 2004-08-05 Cygnus, Inc., Redwood City hydrogel
AUPN487495A0 (en) 1995-08-18 1995-09-14 Cardiac Crc Nominees Pty Limited A multipolar transmural probe
US5879367A (en) * 1995-09-08 1999-03-09 Integ, Inc. Enhanced interstitial fluid collection
ATE287660T1 (en) 1995-12-19 2005-02-15 Abbott Lab DEVICE FOR DETECTING AN ANALYTE AND ADMINISTERING A THERAPEUTIC SUBSTANCE
US5783556A (en) 1996-08-13 1998-07-21 Genentech, Inc. Formulated insulin-containing composition
US6544193B2 (en) * 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
US5914026A (en) 1997-01-06 1999-06-22 Implanted Biosystems Inc. Implantable sensor employing an auxiliary electrode
US6293925B1 (en) 1997-12-31 2001-09-25 Minimed Inc. Insertion device for an insertion set and method of using the same
US5913833A (en) 1997-02-07 1999-06-22 Abbott Laboratories Method and apparatus for obtaining biological fluids
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US7899511B2 (en) * 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
US6186982B1 (en) * 1998-05-05 2001-02-13 Elan Corporation, Plc Subcutaneous drug delivery device with improved filling system
US5954643A (en) 1997-06-09 1999-09-21 Minimid Inc. Insertion set for a transcutaneous sensor
CA2294610A1 (en) * 1997-06-16 1998-12-23 George Moshe Katz Methods of calibrating and testing a sensor for in vivo measurement of an analyte and devices for use in such methods
US6071294A (en) * 1997-12-04 2000-06-06 Agilent Technologies, Inc. Lancet cartridge for sampling blood
US6579690B1 (en) * 1997-12-05 2003-06-17 Therasense, Inc. Blood analyte monitoring through subcutaneous measurement
US7066884B2 (en) * 1998-01-08 2006-06-27 Sontra Medical, Inc. System, method, and device for non-invasive body fluid sampling and analysis
US6103033A (en) 1998-03-04 2000-08-15 Therasense, Inc. Process for producing an electrochemical biosensor
US6091975A (en) * 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
US6175752B1 (en) * 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6272364B1 (en) 1998-05-13 2001-08-07 Cygnus, Inc. Method and device for predicting physiological values
WO1999058050A1 (en) 1998-05-13 1999-11-18 Cygnus, Inc. Signal processing for measurement of physiological analytes
DK1077634T3 (en) 1998-05-13 2003-11-24 Cygnus Therapeutic Systems Monitoring of physiological analytes
US6302855B1 (en) 1998-05-20 2001-10-16 Novo Nordisk A/S Medical apparatus for use by a patient for medical self treatment of diabetes
US6558320B1 (en) * 2000-01-20 2003-05-06 Medtronic Minimed, Inc. Handheld personal data assistant (PDA) with a medical device and method of using the same
US6248067B1 (en) * 1999-02-05 2001-06-19 Minimed Inc. Analyte sensor and holter-type monitor system and method of using the same
US6254586B1 (en) * 1998-09-25 2001-07-03 Minimed Inc. Method and kit for supplying a fluid to a subcutaneous placement site
JP4469504B2 (en) 1998-10-08 2010-05-26 メドトロニック ミニメド インコーポレイテッド Remote trait monitor system
CA2352974A1 (en) 1998-12-18 2000-06-22 John H. Livingston Insertion sets with micro-piercing members for use with medical devices and methods of using the same
US6424847B1 (en) * 1999-02-25 2002-07-23 Medtronic Minimed, Inc. Glucose monitor calibration methods
US6360888B1 (en) * 1999-02-25 2002-03-26 Minimed Inc. Glucose sensor package system
US6132449A (en) * 1999-03-08 2000-10-17 Agilent Technologies, Inc. Extraction and transportation of blood for analysis
CA2366753A1 (en) 1999-04-07 2000-10-12 Michael R. Hatch Assay device for measuring characteristics of a fluid on a continual basis
PT1189660E (en) * 1999-06-08 2006-09-29 Altea Therapeutics Corp EQUIPMENT FOR FORMING MICROPORTS IN BIOLOGICAL MEMBRANES USING INTERFACE DEVICES FOR FINE FILM FABRIC AND PROCESS FOR THE SAME
US6471689B1 (en) 1999-08-16 2002-10-29 Thomas Jefferson University Implantable drug delivery catheter system with capillary interface
AT408182B (en) * 1999-09-17 2001-09-25 Schaupp Lukas Dipl Ing Dr Tech DEVICE FOR VIVO MEASURING SIZES IN LIVING ORGANISMS
JP2003514244A (en) * 1999-11-19 2003-04-15 スペクトルクス，インコーポレイティド Tissue interface device
DE60130536T2 (en) 2000-02-10 2008-06-26 Medtronic MiniMed, Inc., Northridge ANALYTENSENSOR
US7003336B2 (en) * 2000-02-10 2006-02-21 Medtronic Minimed, Inc. Analyte sensor method of making the same
US6484045B1 (en) 2000-02-10 2002-11-19 Medtronic Minimed, Inc. Analyte sensor and method of making the same
US6895263B2 (en) * 2000-02-23 2005-05-17 Medtronic Minimed, Inc. Real time self-adjusting calibration algorithm
WO2001069222A2 (en) 2000-03-17 2001-09-20 F. Hoffmann-La Roche Ag Implantable analyte sensor
US6405066B1 (en) 2000-03-17 2002-06-11 The Regents Of The University Of California Implantable analyte sensor
US7769420B2 (en) * 2000-05-15 2010-08-03 Silver James H Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction
US6442413B1 (en) * 2000-05-15 2002-08-27 James H. Silver Implantable sensor
US7181261B2 (en) 2000-05-15 2007-02-20 Silver James H Implantable, retrievable, thrombus minimizing sensors
WO2001088534A2 (en) 2000-05-16 2001-11-22 Cygnus, Inc. Methods for improving performance and reliability of biosensors
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
WO2002002755A2 (en) 2000-07-05 2002-01-10 Bayer Aktiengesellschaft Regulation of human thimet oligopeptidase-like enzyme
US6589229B1 (en) * 2000-07-31 2003-07-08 Becton, Dickinson And Company Wearable, self-contained drug infusion device
US20020072720A1 (en) 2000-12-11 2002-06-13 Hague Clifford W. Rigid soluble materials for use with needle-less infusion sets, sensor sets and injection devices and methods of making the same
US7310543B2 (en) * 2001-03-26 2007-12-18 Kumetrix, Inc. Silicon microprobe with integrated biosensor
JP3310270B1 (en) * 2001-03-28 2002-08-05 宮子 鎌田 Medical injection needle and method of manufacturing the same
US6454710B1 (en) 2001-04-11 2002-09-24 Motorola, Inc. Devices and methods for monitoring an analyte
US6613379B2 (en) 2001-05-08 2003-09-02 Isense Corp. Implantable analyte sensor
US6793632B2 (en) 2001-06-12 2004-09-21 Lifescan, Inc. Percutaneous biological fluid constituent sampling and measurement devices and methods
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
CN1282870C (en) 2001-09-11 2006-11-01 爱科来株式会社 Measuring instrument, installation body, and density measurer
US20050101841A9 (en) * 2001-12-04 2005-05-12 Kimberly-Clark Worldwide, Inc. Healthcare networks with biosensors
US7018336B2 (en) * 2001-12-27 2006-03-28 Medtronic Minimed, Inc. Implantable sensor flush sleeve
US20030181794A1 (en) 2002-01-29 2003-09-25 Rini Christopher J. Implantable sensor housing, sensor unit and methods for forming and using the same
US6936006B2 (en) * 2002-03-22 2005-08-30 Novo Nordisk, A/S Atraumatic insertion of a subcutaneous device
JP4025567B2 (en) * 2002-03-29 2007-12-19 テルモ株式会社 Needle
US7297122B2 (en) * 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US20070227907A1 (en) 2006-04-04 2007-10-04 Rajiv Shah Methods and materials for controlling the electrochemistry of analyte sensors
US7060192B2 (en) 2002-05-09 2006-06-13 Lifescan, Inc. Methods of fabricating physiological sample collection devices
US20040010207A1 (en) * 2002-07-15 2004-01-15 Flaherty J. Christopher Self-contained, automatic transcutaneous physiologic sensing system
AU2003287073B2 (en) * 2002-10-11 2009-01-08 Becton, Dickinson And Company System and method for initiating and maintaining continuous, long-term control of a concentration of a substance in a patient using a feedback or model-based controller coupled to a single-needle or multi-needle intradermal (ID) delivery device
WO2004034032A2 (en) 2002-10-11 2004-04-22 Case Western Reserve University Sliver type autonomous biosensors
US7381184B2 (en) * 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US7120483B2 (en) 2003-01-13 2006-10-10 Isense Corporation Methods for analyte sensing and measurement
EP1475113A1 (en) 2003-05-08 2004-11-10 Novo Nordisk A/S External needle inserter
US20040254433A1 (en) * 2003-06-12 2004-12-16 Bandis Steven D. Sensor introducer system, apparatus and method
US20050051427A1 (en) * 2003-07-23 2005-03-10 Brauker James H. Rolled electrode array and its method for manufacture
US7424318B2 (en) * 2003-12-05 2008-09-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7366556B2 (en) * 2003-12-05 2008-04-29 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7460898B2 (en) 2003-12-05 2008-12-02 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US20070173710A1 (en) * 2005-04-08 2007-07-26 Petisce James R Membranes for an analyte sensor
US7467003B2 (en) * 2003-12-05 2008-12-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7761130B2 (en) 2003-07-25 2010-07-20 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8845536B2 (en) 2003-08-01 2014-09-30 Dexcom, Inc. Transcutaneous analyte sensor
US20070208245A1 (en) 2003-08-01 2007-09-06 Brauker James H Transcutaneous analyte sensor
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US8886273B2 (en) * 2003-08-01 2014-11-11 Dexcom, Inc. Analyte sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US20080119703A1 (en) * 2006-10-04 2008-05-22 Mark Brister Analyte sensor
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US7494465B2 (en) * 2004-07-13 2009-02-24 Dexcom, Inc. Transcutaneous analyte sensor
US8233959B2 (en) * 2003-08-22 2012-07-31 Dexcom, Inc. Systems and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US7723099B2 (en) 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
WO2005048834A1 (en) 2003-11-13 2005-06-02 Medtronic Minimed, Inc. Long term analyte sensor array
US20080200788A1 (en) 2006-10-04 2008-08-21 Dexcorn, Inc. Analyte sensor
US8364231B2 (en) * 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US8364230B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US8425416B2 (en) 2006-10-04 2013-04-23 Dexcom, Inc. Analyte sensor
EP2256493B1 (en) * 2003-12-05 2014-02-26 DexCom, Inc. Calibration techniques for a continuous analyte sensor
US20080197024A1 (en) 2003-12-05 2008-08-21 Dexcom, Inc. Analyte sensor
DK1706019T3 (en) * 2003-12-22 2009-02-02 Paul Hadvary Dermally attached sensor device
FR2864449A1 (en) * 2003-12-29 2005-07-01 Ela Medical Sa ACTIVE IMPLANTABLE MEDICAL DEVICE, IN PARTICULAR A CARDIAC STIMULATOR, WITH IMPROVED MANAGEMENT OF AUTOMATIC AAI / DDD MODE SWITCHING IN THE PRESENCE OF PAROXYSTIC BAV
US8452368B2 (en) * 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US8170803B2 (en) * 2004-07-13 2012-05-01 Dexcom, Inc. Transcutaneous analyte sensor
US8886272B2 (en) * 2004-07-13 2014-11-11 Dexcom, Inc. Analyte sensor
US20080242961A1 (en) 2004-07-13 2008-10-02 Dexcom, Inc. Transcutaneous analyte sensor
US20070045902A1 (en) * 2004-07-13 2007-03-01 Brauker James H Analyte sensor
EP1784249A2 (en) 2004-08-16 2007-05-16 Novo Nordisk A/S Multiphase biocompatible semi-permeable membrane for biosensors
US7468033B2 (en) * 2004-09-08 2008-12-23 Medtronic Minimed, Inc. Blood contacting sensor
US8224414B2 (en) * 2004-10-28 2012-07-17 Echo Therapeutics, Inc. System and method for analyte sampling and analysis with hydrogel
US7179055B2 (en) 2004-12-16 2007-02-20 Revene Philip M Mailable fan
US20110073475A1 (en) 2009-08-29 2011-03-31 Abbott Diabetes Care Inc. Analyte Sensor
US8333714B2 (en) 2006-09-10 2012-12-18 Abbott Diabetes Care Inc. Method and system for providing an integrated analyte sensor insertion device and data processing unit
US8512243B2 (en) * 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US9259175B2 (en) * 2006-10-23 2016-02-16 Abbott Diabetes Care, Inc. Flexible patch for fluid delivery and monitoring body analytes
US9398882B2 (en) 2005-09-30 2016-07-26 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor and data processing device
US8133178B2 (en) * 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
US20090076360A1 (en) * 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
WO2006105146A2 (en) 2005-03-29 2006-10-05 Arkal Medical, Inc. Devices, systems, methods and tools for continuous glucose monitoring
WO2007059476A2 (en) 2005-11-15 2007-05-24 Luminous Medical, Inc. Blood analyte determinations
WO2006110193A2 (en) 2005-04-08 2006-10-19 Dexcom, Inc. Cellulosic-based interference domain for an analyte sensor
US20060253085A1 (en) 2005-05-06 2006-11-09 Medtronic Minimed, Inc. Dual insertion set
US20060263839A1 (en) 2005-05-17 2006-11-23 Isense Corporation Combined drug delivery and analyte sensor apparatus
EP3649925A1 (en) 2006-02-22 2020-05-13 DexCom, Inc. Analyte sensor
WO2007120381A2 (en) 2006-04-14 2007-10-25 Dexcom, Inc. Analyte sensor
GB0612834D0 (en) 2006-06-28 2006-08-09 Glysure Ltd Sensor calibration
US9119582B2 (en) 2006-06-30 2015-09-01 Abbott Diabetes Care, Inc. Integrated analyte sensor and infusion device and methods therefor
US8562528B2 (en) * 2006-10-04 2013-10-22 Dexcom, Inc. Analyte sensor
US8298142B2 (en) * 2006-10-04 2012-10-30 Dexcom, Inc. Analyte sensor
US8447376B2 (en) * 2006-10-04 2013-05-21 Dexcom, Inc. Analyte sensor
US8449464B2 (en) * 2006-10-04 2013-05-28 Dexcom, Inc. Analyte sensor
US8275438B2 (en) * 2006-10-04 2012-09-25 Dexcom, Inc. Analyte sensor
US8478377B2 (en) * 2006-10-04 2013-07-02 Dexcom, Inc. Analyte sensor
US7831287B2 (en) 2006-10-04 2010-11-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US20080139903A1 (en) 2006-12-08 2008-06-12 Isense Corporation Method and apparatus for insertion of a sensor using an introducer
WO2008115745A2 (en) * 2007-03-19 2008-09-25 University Of Virginia Patent Foundation Access needle pressure sensor device and method of use
JP5581310B2 (en) 2008-03-17 2014-08-27 アイセンス コーポレーション Analyte sensor subassembly
US10376213B2 (en) 2009-06-30 2019-08-13 Waveform Technologies, Inc. System, method and apparatus for sensor insertion
CN102724913A (en) * 2009-09-30 2012-10-10 德克斯康公司 Transcutaneous analyte sensor
EP2436311A1 (en) * 2010-10-04 2012-04-04 PharmaSens AG Diagnostic device
US20140213866A1 (en) 2012-10-12 2014-07-31 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods
US20150289788A1 (en) 2014-04-10 2015-10-15 Dexcom, Inc. Sensors for continuous analyte monitoring, and related methods

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807375A (en) * 1994-11-04 1998-09-15 Elan Medical Technologies Limited Analyte-controlled liquid delivery device and analyte monitor
US20070129619A1 (en) * 2003-06-16 2007-06-07 Isense Corporation Compound material analyte sensor
US20080033269A1 (en) * 2004-12-08 2008-02-07 San Medi Tech (Huzhou) Co., Ltd. Catheter-free implantable needle biosensor

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US20160157766A1 (en) 2016-06-09
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US20110077490A1 (en) 2011-03-31
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US9357951B2 (en) 2016-06-07
US10835161B2 (en) 2020-11-17

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