WO2010121919A1 - Hair care composition comprising trichogen complex and an azole - Google Patents
Hair care composition comprising trichogen complex and an azole Download PDFInfo
- Publication number
- WO2010121919A1 WO2010121919A1 PCT/EP2010/054802 EP2010054802W WO2010121919A1 WO 2010121919 A1 WO2010121919 A1 WO 2010121919A1 EP 2010054802 W EP2010054802 W EP 2010054802W WO 2010121919 A1 WO2010121919 A1 WO 2010121919A1
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- WO
- WIPO (PCT)
- Prior art keywords
- hair treatment
- treatment composition
- composition according
- mixtures
- extract
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
Definitions
- the present invention relates to hair care compositions in particular compositions that maximize hair growth.
- Hair growth is of commercial interest to many groups of consumer.
- Male baldness or hair thinning is a problem for one market segment, a second market segment is people who are not bald but require their hair to appear thick and voluminous.
- the predominant products are pharmaceuticals, although not all the products that are marketed in this segment are drug products.
- the prior art includes many patents disclosing hair grooming compositions which illustrate the state of the art in herbal based compositions for promoting hair health and growth.
- U.S. Pat. No. 604,111 discloses a hair tonic of mountain sage, glycerin, tincture of lobelia, prickly pear juice, tincture of capsicum, sweet oil, and alcohol, which cleans the scalp, relaxes and stimulates the scalp, cools the scalp and gives the hair gloss.
- US 2007/0036742 discloses a composition for preventing or decreasing hair loss comprising a mixture of plant extracts such as green tea.
- US 6 232 302 discloses compositions comprising depolymehses fucane sulphates for increasing hair growth.
- compositions comprising cysteine, lysine, and a glycoprotein are disclosed in EP 1 089 704 for trichological use. Despite the prior art there remains the need for improved compositions for reducing hair loss.
- the present invention relates to a hair treatment composition
- a hair treatment composition comprising a trichogenic material and from 0.0002 to 0.0049 of an additional anti-dandruff agent.
- the composition of the invention comprises a trichogenic material.
- the trichogenic material comprises a synergistic trichogenic mixture of the following: a protein biosynthesis stimulant preferably selected from a sulfopeptide of soy, amino acids, glutamine, glutamic acid, hydrolysed protein extracts, particularly preferred are sulfopeptides of soy and amino acids, especially tyrosine, arginine, ornithine and citrulline.
- the synergistic trichogenic mixture may comprise a glycosamino production agent is selected from the group consisting of glucosamine, L-fucose; fucose rich polysaccharide, xylose,vitamin C, Eriobotrya japonica extract, N-acetyl glucosamine, glucosamine sulphate, lysophospholipids, protamine and mixtures thereof. Particularly preferred is glucosamine.
- the synergistic trichogenic mixture may comprise a cell nutrition regulator especially vitamins of the B group, carnitine, co-enzyme Q10, creatine, taurine, acetyl-carnitine and mixtures thereof. Particularly preferred are vitamins of the B group, especially PP, B5 and biotin.
- the synergistic trichogenic mixture may comprise a microcirculation promoter, preferred promoters are Panax Ginseng Extract, Arctium Majus Extract, nitric oxide, niacin, caffeine, gingko biloba extract, bicyclic monoterpene diols, ⁇ -lipoic acid, ximenynic acid, proanthocyanidins, arginine and mixtures thereof. Particularly preferred are Panax Ginseng Extract, Arctium Majus Extract.
- the trichogenic material comprises a synergistic mixture of a healthy scalp protein biosynthesis stimulant, a glycosamino production agent, a cell nutrition regulator, a microcirculation promotor and mixtures thereof.
- the protein biosynthesis stimulant is selected from a sulfopeptide of soy, amino acids, glutamine, glutamic acid, hydrolysed protein extracts.
- the glycosamino production agent is selected from glucosamine, L- fucose; fucose rich polysaccharide xylose,vitamin C, Eriobotrya Japonica extract, N-acetyl glucosamine, glucosamine sulphate, lysophospholipids, protamine and mixtures thereof.
- the cell nutrition regulator is selected from vitamins of the B group, carnitine, co-enzyme Q10, creatine, taurine, acetyl-carnitine and mixtures thereof.
- the microcirculation promoter is selected from Panax Ginseng Extract, Arctium Majus Extract, nitric oxide, niacin, caffeine, gingko biloba extract, bicyclic monoterpene diols, a-lipoic acid, ximenynic acid, proanthocyanidins, arginine and mixtures thereof.
- Thchogen® ex Cognis in particular Trichogen® Veg LS 8960.
- the level of the synergistic trichogenic mixture is preferably from 0.001 to 20 wt% of the total composition, more preferably from 0.1 to 15 wt% of the total composition, most preferably from 0.2 1 10 wt% of the total composition.
- the antidandruff agent is selected from the group consisting of zinc pyrithione, octopirox, climbazole, ketoconazole and mixtures thereof.
- Azole based antidandruff agents are the most preferred, in particular climbazole.
- the anti-dandruff agent is therefore preferably soluble in the composition of the invention at 25°C.
- the level of anti-dandruff agent is preferably from 0.0002 to 0.0049 wt%, more preferably from 0.0007 to 0.003 wt% of the total composition.
- composition of the invention further comprises an ant- inflammatory agent.
- the anti-inflammatory agent is selected from the group consisting of hyssop extract, turmeric extract, arnica extract, willow bark extract, sesquiterpene extract, salicylic acid and mixtures thereof.
- An especially preferred anti-inflammatory agent is salicylic acid.
- the final product form of hair treatment compositions according to the invention may suitably be, for example, shampoos, conditioners, sprays, mousses, gels, oils, creams, waxes or lotions.
- Particularly preferred product forms are leave-on products (those products that are not immediately rinsed off after application and are preferably left on for at least one hour, more preferably for at least 5 hours).
- Post-wash conditioners are preferred (especially leave-in) as are hair treatment products such as hair essences.
- composition according to the invention is preferably a conditioning composition and will comprise a conditioning active.
- conditioning actives include fatty alcohols, cationic surfactants and silicones.
- the amount of product applied will vary according to the form of the product, but will normally be in accordance with the industry accepted methodology for the use of a product of the same type.
- a representative application procedure will involve application of the formulation to the area in need of treatment once or twice a day, and leaving the formulation in place for a period of several hours.
- the following experiment uses trypsin as a model for the serine proteases involved in the process of hair fall. Successful inhibition the activity of the serine proteases such as trypsin is thought to delay the onset of hair fall.
- the EnzChek Protease Assay (E6639, Molecular Probes) was used to measure trypsin activity.
- Lexamine S13 Ex Inolex Chemical Company is Stearamidopropyl Dimethylamine.
- Ganamin BTLF (ex Clariant) is Behenthmonium Chloride Laurex CS (ex Albright and Wilson) is Cetearyl Alcohol. Leave-on serum
- Carbopol Ultrez 20 (ex Noveon) is a hydrophobically modified cross-linked acrylate copolymer (Acrylates/C 10-30 Alkyl Acrylate Crosspolymer).
- Rhodasurf L790 is polyoxyethylene 7 lauryl alcohol (Laureth-7).
- Eumulgin L (ex Cognis) is PPG-1 -PEG-9 Lauryl Glycol Ether.
Abstract
A hair treatment composition comprising a trichogenic material and from 0.0002 to 0.0049% wt. of an additional anti-dandruff agent.
Description
HAIR CARE COMPOSITION COMPRISING TRICHOGEN COMPLEX AND AN AZOLE
The present invention relates to hair care compositions in particular compositions that maximize hair growth.
Hair growth is of commercial interest to many groups of consumer. Male baldness or hair thinning is a problem for one market segment, a second market segment is people who are not bald but require their hair to appear thick and voluminous. For male baldness the predominant products are pharmaceuticals, although not all the products that are marketed in this segment are drug products.
The prior art includes many patents disclosing hair grooming compositions which illustrate the state of the art in herbal based compositions for promoting hair health and growth.
U.S. Pat. No. 604,111 discloses a hair tonic of mountain sage, glycerin, tincture of lobelia, prickly pear juice, tincture of capsicum, sweet oil, and alcohol, which cleans the scalp, relaxes and stimulates the scalp, cools the scalp and gives the hair gloss.
US 2007/0036742 discloses a composition for preventing or decreasing hair loss comprising a mixture of plant extracts such as green tea.
US 6 232 302 discloses compositions comprising depolymehses fucane sulphates for increasing hair growth.
Compositions comprising cysteine, lysine, and a glycoprotein are disclosed in EP 1 089 704 for trichological use.
Despite the prior art there remains the need for improved compositions for reducing hair loss.
The present invention relates to a hair treatment composition comprising a trichogenic material and from 0.0002 to 0.0049 of an additional anti-dandruff agent.
The composition of the invention comprises a trichogenic material. Preferably the trichogenic material comprises a synergistic trichogenic mixture of the following: a protein biosynthesis stimulant preferably selected from a sulfopeptide of soy, amino acids, glutamine, glutamic acid, hydrolysed protein extracts, particularly preferred are sulfopeptides of soy and amino acids, especially tyrosine, arginine, ornithine and citrulline.
The synergistic trichogenic mixture may comprise a glycosamino production agent is selected from the group consisting of glucosamine, L-fucose; fucose rich polysaccharide, xylose,vitamin C, Eriobotrya japonica extract, N-acetyl glucosamine, glucosamine sulphate, lysophospholipids, protamine and mixtures thereof. Particularly preferred is glucosamine.
The synergistic trichogenic mixture may comprise a cell nutrition regulator especially vitamins of the B group, carnitine, co-enzyme Q10, creatine, taurine, acetyl-carnitine and mixtures thereof. Particularly preferred are vitamins of the B group, especially PP, B5 and biotin.
The synergistic trichogenic mixture may comprise a microcirculation promoter, preferred promoters are Panax Ginseng Extract, Arctium Majus Extract, nitric oxide, niacin, caffeine, gingko biloba extract, bicyclic monoterpene diols, α-lipoic acid, ximenynic acid, proanthocyanidins, arginine and mixtures thereof.
Particularly preferred are Panax Ginseng Extract, Arctium Majus Extract.
Preferably, the trichogenic material comprises a synergistic mixture of a healthy scalp protein biosynthesis stimulant, a glycosamino production agent, a cell nutrition regulator, a microcirculation promotor and mixtures thereof.
Preferably, the protein biosynthesis stimulant is selected from a sulfopeptide of soy, amino acids, glutamine, glutamic acid, hydrolysed protein extracts.
Preferably, the glycosamino production agent is selected from glucosamine, L- fucose; fucose rich polysaccharide xylose,vitamin C, Eriobotrya Japonica extract, N-acetyl glucosamine, glucosamine sulphate, lysophospholipids, protamine and mixtures thereof.
Preferably, the cell nutrition regulator is selected from vitamins of the B group, carnitine, co-enzyme Q10, creatine, taurine, acetyl-carnitine and mixtures thereof.
Preferably, the microcirculation promoter is selected from Panax Ginseng Extract, Arctium Majus Extract, nitric oxide, niacin, caffeine, gingko biloba extract, bicyclic monoterpene diols, a-lipoic acid, ximenynic acid, proanthocyanidins, arginine and mixtures thereof.
A particularly preferred synergistic trichogenic mixture is known as Thchogen® ex Cognis, in particular Trichogen® Veg LS 8960.
The level of the synergistic trichogenic mixture is preferably from 0.001 to 20 wt% of the total composition, more preferably from 0.1 to 15 wt% of the total composition, most preferably from 0.2 1 10 wt% of the total composition.
- A -
The antidandruff agent is selected from the group consisting of zinc pyrithione, octopirox, climbazole, ketoconazole and mixtures thereof. Azole based antidandruff agents are the most preferred, in particular climbazole.
The anti-dandruff agent is therefore preferably soluble in the composition of the invention at 25°C.
The level of anti-dandruff agent is preferably from 0.0002 to 0.0049 wt%, more preferably from 0.0007 to 0.003 wt% of the total composition.
It is preferable if the composition of the invention further comprises an ant- inflammatory agent. Preferably the anti-inflammatory agent is selected from the group consisting of hyssop extract, turmeric extract, arnica extract, willow bark extract, sesquiterpene extract, salicylic acid and mixtures thereof. An especially preferred anti-inflammatory agent is salicylic acid.
The final product form of hair treatment compositions according to the invention may suitably be, for example, shampoos, conditioners, sprays, mousses, gels, oils, creams, waxes or lotions. Particularly preferred product forms are leave-on products (those products that are not immediately rinsed off after application and are preferably left on for at least one hour, more preferably for at least 5 hours). Post-wash conditioners are preferred (especially leave-in) as are hair treatment products such as hair essences.
Accordingly, the composition according to the invention is preferably a conditioning composition and will comprise a conditioning active. Preferred conditioning actives include fatty alcohols, cationic surfactants and silicones.
The amount of product applied will vary according to the form of the product, but will normally be in accordance with the industry accepted methodology for the use
of a product of the same type. A representative application procedure will involve application of the formulation to the area in need of treatment once or twice a day, and leaving the formulation in place for a period of several hours.
The invention is further illustrated by the following non-limiting examples:
Examples
The following experiment uses trypsin as a model for the serine proteases involved in the process of hair fall. Successful inhibition the activity of the serine proteases such as trypsin is thought to delay the onset of hair fall.
The EnzChek Protease Assay (E6639, Molecular Probes) was used to measure trypsin activity.
Example 1
1.5% Trichogen plus 0.00391 % climbazole
Data generated from an enzyme assay. Calculated efficacy is the mean activity of (Climbazole + Trichogen)/2
Experimental activity is the measure activity with the two ingredients present.
EXAMPLE 2
The following are formulations comprising climbazole and trichogen.
Shampoo
Conditioner
Lexamine S13 (ex Inolex Chemical Company is Stearamidopropyl Dimethylamine.
Ganamin BTLF (ex Clariant) is Behenthmonium Chloride Laurex CS (ex Albright and Wilson) is Cetearyl Alcohol.
Leave-on serum
Carbopol Ultrez 20 (ex Noveon) is a hydrophobically modified cross-linked acrylate copolymer (Acrylates/C 10-30 Alkyl Acrylate Crosspolymer).
Rhodasurf L790 (ex Rhodia) is polyoxyethylene 7 lauryl alcohol (Laureth-7).
Eumulgin L (ex Cognis) is PPG-1 -PEG-9 Lauryl Glycol Ether.
Claims
1. A hair treatment composition comprising a thchogenic material and from 0.0002 to 0.0049% wt. of an additional anti-dandruff agent.
2. A hair treatment composition according to claim 1 in which the thchogenic material comprises a synergistic mixture of a healthy scalp protein biosynthesis stimulant, a glycosamino production agent, a cell nutrition regulator, a microcirculation promoter and mixtures thereof.
3. A hair treatment composition according to claim 2 in which the protein biosynthesis stimulant is selected from a sulfopeptide of soy, amino acids, glutamine, glutamic acid, hydrolysed protein extracts.
4. A hair treatment composition according to claim 2 or claim 3 in which the glycosamino production agent is selected from glucosamine, L-fucose; fucose rich polysaccharide xylose,vitamin C, Eriobotrya Japonica extract, N- acetyl glucosamine, glucosamine sulphate, lysophospholipids, protamine and mixtures thereof.
5. A hair treatment composition according to any one of claims 2 to 4 in which the cell nutrition regulator is selected from vitamins of the B group, carnitine, co-enzyme Q10, creatine, taurine, acetyl-carnitine and mixtures thereof.
6. A hair treatment composition according to any one of claims 2 to 5 in which the microcirculation promoter is selected from Panax Ginseng Extract, Arctium Majus Extract, nitric oxide, niacin, caffeine, gingko biloba extract, bicyclic monoterpene diols, a-lipoic acid, ximenynic acid, proanthocyanidins, arginine and mixtures thereof.
7. A hair treatment composition according to any preceding claim in which the level of the trichogenic material is from 0.1 to 20 wt% of the total composition.
8. A hair treatment composition according to any preceding claim in which the anti-dandruff agent is selected from the group consisting of zinc pyrithione, octopirox, climbazole, ketoconazole or mixtures thereof.
9. A hair treatment composition according to claim 7 in which the anti-dandruff agent is an azole.
10. A hair treatment composition according to claim 9 in which the anti-dandruff agent is climbazole.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09158656.0 | 2009-04-23 | ||
| EP09158656 | 2009-04-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2010121919A1 true WO2010121919A1 (en) | 2010-10-28 |
Family
ID=41066034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2010/054802 WO2010121919A1 (en) | 2009-04-23 | 2010-04-13 | Hair care composition comprising trichogen complex and an azole |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2010121919A1 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013083645A2 (en) | 2011-12-07 | 2013-06-13 | Unilever Plc | Skin lightening composition |
| CN104168883A (en) * | 2013-09-12 | 2014-11-26 | 拉芳家化股份有限公司 | Shampoo composition including efficient anti-remval agent |
| WO2018064468A1 (en) * | 2016-09-30 | 2018-04-05 | The Regents Of The University Of California | Alpha-ketobutyrate, alpha-ketoglutarate, and 2-hydroxybutyrate for stimulating hair growth |
| US11800917B2 (en) * | 2018-08-30 | 2023-10-31 | L'oreal | Hair-treatment compositions and methods of use |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US604111A (en) | 1898-05-17 | Hair-tonic | ||
| EP0489581A2 (en) * | 1990-12-04 | 1992-06-10 | Unilever Plc | Cosmetic composition |
| EP0674897A2 (en) * | 1994-03-31 | 1995-10-04 | Shiseido Company Limited | Hair composition |
| EP1089704A1 (en) | 1998-06-22 | 2001-04-11 | Gecomwert Anstalt | Trichological lotion for topical use |
| US6232302B1 (en) | 1998-06-16 | 2001-05-15 | Crinos Industria Farmacobiologica S.P.A. | Agents and compositions thereof for the hair treatment |
| US6284234B1 (en) * | 1998-08-04 | 2001-09-04 | Johnson & Johnson Consumer Companies, Inc. | Topical delivery systems for active agents |
| WO2002007700A2 (en) * | 2000-07-26 | 2002-01-31 | The Procter & Gamble Company | Compositions useful for regulating hair growth containing metal complexes of oxidized carbohydrates |
| US20070036742A1 (en) | 2005-08-09 | 2007-02-15 | Access Business Group International Llc | Methods and compositions for modulating hair growth or regrowth |
-
2010
- 2010-04-13 WO PCT/EP2010/054802 patent/WO2010121919A1/en active Application Filing
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US604111A (en) | 1898-05-17 | Hair-tonic | ||
| EP0489581A2 (en) * | 1990-12-04 | 1992-06-10 | Unilever Plc | Cosmetic composition |
| EP0674897A2 (en) * | 1994-03-31 | 1995-10-04 | Shiseido Company Limited | Hair composition |
| US6232302B1 (en) | 1998-06-16 | 2001-05-15 | Crinos Industria Farmacobiologica S.P.A. | Agents and compositions thereof for the hair treatment |
| EP1089704A1 (en) | 1998-06-22 | 2001-04-11 | Gecomwert Anstalt | Trichological lotion for topical use |
| US6284234B1 (en) * | 1998-08-04 | 2001-09-04 | Johnson & Johnson Consumer Companies, Inc. | Topical delivery systems for active agents |
| WO2002007700A2 (en) * | 2000-07-26 | 2002-01-31 | The Procter & Gamble Company | Compositions useful for regulating hair growth containing metal complexes of oxidized carbohydrates |
| US20070036742A1 (en) | 2005-08-09 | 2007-02-15 | Access Business Group International Llc | Methods and compositions for modulating hair growth or regrowth |
Non-Patent Citations (1)
| Title |
|---|
| TIM FABER: "Trichogen Complex-Stop Hair Loss and PRomote Hair Growth", EZINE @RTICLES, 3 June 2008 (2008-06-03), XP002546966, Retrieved from the Internet <URL:http://ezinearticles.com/?Trichogen-Complex---Stop-Hair-Loss-and-Promote-Hair-Growth&id=1222597> * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013083645A2 (en) | 2011-12-07 | 2013-06-13 | Unilever Plc | Skin lightening composition |
| CN104168883A (en) * | 2013-09-12 | 2014-11-26 | 拉芳家化股份有限公司 | Shampoo composition including efficient anti-remval agent |
| WO2015035585A1 (en) * | 2013-09-12 | 2015-03-19 | 拉芳家化股份有限公司 | Shampoo composition containing complexing agent for efficiently preventing hair loss |
| CN104168883B (en) * | 2013-09-12 | 2016-05-25 | 拉芳家化股份有限公司 | A kind of shampoo composite containing efficient anticreep complexing agent |
| WO2018064468A1 (en) * | 2016-09-30 | 2018-04-05 | The Regents Of The University Of California | Alpha-ketobutyrate, alpha-ketoglutarate, and 2-hydroxybutyrate for stimulating hair growth |
| US11800917B2 (en) * | 2018-08-30 | 2023-10-31 | L'oreal | Hair-treatment compositions and methods of use |
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