WO2010089259A3 - Sustained release composition containing quetiapine - Google Patents

Sustained release composition containing quetiapine Download PDF

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Publication number
WO2010089259A3
WO2010089259A3 PCT/EP2010/051098 EP2010051098W WO2010089259A3 WO 2010089259 A3 WO2010089259 A3 WO 2010089259A3 EP 2010051098 W EP2010051098 W EP 2010051098W WO 2010089259 A3 WO2010089259 A3 WO 2010089259A3
Authority
WO
WIPO (PCT)
Prior art keywords
sustained release
composition containing
release composition
pharmaceutical composition
containing quetiapine
Prior art date
Application number
PCT/EP2010/051098
Other languages
French (fr)
Other versions
WO2010089259A2 (en
Inventor
Juergen Heim
Sandra Weigel
Original Assignee
Woerwag R&D Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Woerwag R&D Gmbh filed Critical Woerwag R&D Gmbh
Publication of WO2010089259A2 publication Critical patent/WO2010089259A2/en
Publication of WO2010089259A3 publication Critical patent/WO2010089259A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Abstract

The present invention is directed to a sustained release pharmaceutical composition containing quetiapine, a pharmaceutically acceptable salt or a derivative thereof, which allows a once-a-day administration of said sustained release pharmaceutical composition to a patient in need thereof. The present invention is further directed to the use of this composition for the treatment of schizophrenia and acute manic episodes associated with bipolar I disorder, and to a process for preparing the pharmaceutical composition.
PCT/EP2010/051098 2009-02-04 2010-01-29 Sustained release composition containing quetiapine WO2010089259A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09151996 2009-02-04
EP09151996.7 2009-02-04

Publications (2)

Publication Number Publication Date
WO2010089259A2 WO2010089259A2 (en) 2010-08-12
WO2010089259A3 true WO2010089259A3 (en) 2011-07-07

Family

ID=42060688

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2010/051098 WO2010089259A2 (en) 2009-02-04 2010-01-29 Sustained release composition containing quetiapine

Country Status (1)

Country Link
WO (1) WO2010089259A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201008261A1 (en) * 2010-10-08 2012-04-24 Sanovel İlaç San. Ve Ti̇c. A.Ş. Controlled release quetiapine formulations
WO2014155387A1 (en) * 2013-03-24 2014-10-02 Tushar Patel Extended release dosage forms of quetiapine salts
CN103315973B (en) * 2013-05-24 2014-05-07 杭州和正医药有限公司 Quetiapine osmotic pump controlled release preparation
CN104688709A (en) * 2015-03-24 2015-06-10 北京世桥生物制药有限公司 Fumaric acid quetiapine composition sustained-release tablet and preparing method thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948437A (en) * 1996-05-23 1999-09-07 Zeneca Limited Pharmaceutical compositions using thiazepine
WO2005041935A1 (en) * 2003-10-21 2005-05-12 Alpharma, Inc. Pharmaceutical formulations containing quetiapine
WO2007086079A2 (en) * 2006-01-25 2007-08-02 Astron Research Limited Sustained release dosage form of phenothiazine derivatives containing channelizer
WO2008060228A1 (en) * 2006-11-17 2008-05-22 Astrazeneca Ab Extended release formulations comprising quetipine and methods for their manufacture
WO2008090569A1 (en) * 2007-01-25 2008-07-31 Panacea Biotec Ltd Modified release pharmaceutical composition and a process of making the same
EP2153834A2 (en) * 2008-08-07 2010-02-17 Farmaprojects, S.A. Extended release pharmaceutical compositions comprising quetiapine salts
WO2010028794A1 (en) * 2008-09-10 2010-03-18 Alfred E. Tiefenbacher Gmbh & Co. Kg Retard tablets containing quetiapine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607684D0 (en) 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
GB8705574D0 (en) 1987-03-10 1987-04-15 Ici Plc Preparation of thiazepine compound
GB9611328D0 (en) 1996-05-31 1996-08-07 Zeneca Ltd Pharmaceutical compositions
US20030185882A1 (en) 2001-11-06 2003-10-02 Vergez Juan A. Pharmaceutical compositions containing oxybutynin
US7611728B2 (en) 2003-09-05 2009-11-03 Supernus Pharmaceuticals, Inc. Osmotic delivery of therapeutic compounds by solubility enhancement
CA2613403A1 (en) 2005-06-29 2007-01-04 Panacea Biotec Ltd. Modified release pharmaceutical compositions on the basis of two polymers and processes thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948437A (en) * 1996-05-23 1999-09-07 Zeneca Limited Pharmaceutical compositions using thiazepine
WO2005041935A1 (en) * 2003-10-21 2005-05-12 Alpharma, Inc. Pharmaceutical formulations containing quetiapine
WO2007086079A2 (en) * 2006-01-25 2007-08-02 Astron Research Limited Sustained release dosage form of phenothiazine derivatives containing channelizer
WO2008060228A1 (en) * 2006-11-17 2008-05-22 Astrazeneca Ab Extended release formulations comprising quetipine and methods for their manufacture
WO2008090569A1 (en) * 2007-01-25 2008-07-31 Panacea Biotec Ltd Modified release pharmaceutical composition and a process of making the same
EP2153834A2 (en) * 2008-08-07 2010-02-17 Farmaprojects, S.A. Extended release pharmaceutical compositions comprising quetiapine salts
WO2010028794A1 (en) * 2008-09-10 2010-03-18 Alfred E. Tiefenbacher Gmbh & Co. Kg Retard tablets containing quetiapine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"EXTENDED RELEASE PHARMACEUTICAL COMPOSITIONS OF QUETIAPINE", IP.COM JOURNAL, IP.COM INC., WEST HENRIETTA, NY, US, 1 December 2008 (2008-12-01), XP013128235, ISSN: 1533-0001 *
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 7 February 2008 (2008-02-07), XP002633914, Database accession no. 148:151916 *
KUCHEKAR B ET AL: "preformulation and formulation studies of novel pH independent controlled release drug delivery system of quetiapnie fumarate", JOURNAL OF PHARMACY RESEARCH,, vol. 2, no. 1, 1 January 2009 (2009-01-01), pages 110 - 119, XP008135863, ISSN: 0974-6943 *

Also Published As

Publication number Publication date
WO2010089259A2 (en) 2010-08-12

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