WO2010077997A3 - Method and apparatus for determining heart rate variability using wavelet transformation - Google Patents

Method and apparatus for determining heart rate variability using wavelet transformation Download PDF

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Publication number
WO2010077997A3
WO2010077997A3 PCT/US2009/068336 US2009068336W WO2010077997A3 WO 2010077997 A3 WO2010077997 A3 WO 2010077997A3 US 2009068336 W US2009068336 W US 2009068336W WO 2010077997 A3 WO2010077997 A3 WO 2010077997A3
Authority
WO
WIPO (PCT)
Prior art keywords
wavelet transformation
heart rate
rate variability
extent
determining heart
Prior art date
Application number
PCT/US2009/068336
Other languages
French (fr)
Other versions
WO2010077997A2 (en
Inventor
Kayvan Najarian
Kevin Ward
David Andre
Nisarg Vyas
Eric Teller
John M. Stivoric
Jonathan Farringdon
Scott Boehmke
James Gasbarro
Soo-Yeon Ji
Abed Al Raoof
Raymond Pelletier
Original Assignee
Bodymedia, Inc.
Virginia Commonwealth University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2009/006234 external-priority patent/WO2010065067A1/en
Application filed by Bodymedia, Inc., Virginia Commonwealth University filed Critical Bodymedia, Inc.
Priority to US13/140,165 priority Critical patent/US20120123232A1/en
Priority to CA2747057A priority patent/CA2747057A1/en
Priority to EP09836926.7A priority patent/EP2375973A4/en
Publication of WO2010077997A2 publication Critical patent/WO2010077997A2/en
Publication of WO2010077997A3 publication Critical patent/WO2010077997A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02405—Determining heart rate variability
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346—Analysis of electrocardiograms
    • A61B5/349—Detecting specific parameters of the electrocardiograph cycle
    • A61B5/366—Detecting abnormal QRS complex, e.g. widening
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/412—Detecting or monitoring sepsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7253—Details of waveform analysis characterised by using transforms
    • A61B5/726—Details of waveform analysis characterised by using transforms using Wavelet transforms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/02208—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers using the Korotkoff method
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/22—Ergometry; Measuring muscular strength or the force of a muscular blow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6824—Arm or wrist
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • A61B5/721—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts using a separate sensor to detect motion or using motion information derived from signals other than the physiological signal to be measured
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7239—Details of waveform analysis using differentiation including higher order derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A61B5/7267—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device

Abstract

The present invention relates to advanced signal processing methods including digital wavelet transformation to analyze heart-related electronic signals and extract features that can accurately identify various states of the cardiovascular system. The invention may be utilized to estimate the extent of blood volume loss, distinguish blood volume loss from physiological activities associated with exercise, and predict the presence and extent of cardiovascular disease in general.
PCT/US2009/068336 2008-12-16 2009-12-16 Method and apparatus for determining heart rate variability using wavelet transformation WO2010077997A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US13/140,165 US20120123232A1 (en) 2008-12-16 2009-12-16 Method and apparatus for determining heart rate variability using wavelet transformation
CA2747057A CA2747057A1 (en) 2008-12-16 2009-12-16 Method and apparatus for determining heart rate variability using wavelet transformation
EP09836926.7A EP2375973A4 (en) 2008-12-16 2009-12-16 Method and apparatus for determining heart rate variability using wavelet transformation

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US12280408P 2008-12-16 2008-12-16
US61/122,804 2008-12-16
US16728709P 2009-04-07 2009-04-07
US61/167,287 2009-04-07
PCT/US2009/006234 WO2010065067A1 (en) 2008-11-20 2009-11-20 Method and apparatus for determining critical care parameters
USPCT/US2009/006234 2009-11-20

Publications (2)

Publication Number Publication Date
WO2010077997A2 WO2010077997A2 (en) 2010-07-08
WO2010077997A3 true WO2010077997A3 (en) 2010-10-14

Family

ID=42310544

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/068336 WO2010077997A2 (en) 2008-12-16 2009-12-16 Method and apparatus for determining heart rate variability using wavelet transformation

Country Status (3)

Country Link
EP (1) EP2375973A4 (en)
CA (1) CA2747057A1 (en)
WO (1) WO2010077997A2 (en)

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US9839364B2 (en) 2009-10-06 2017-12-12 University Of Virginia Patent Foundation Ventricular activation (RR) entropy change as a predictor of sudden cardiac death in cardiac resynchronization therapy patients
BR112012029240A2 (en) 2010-05-18 2017-05-30 Zoll Medical Corp ambulatory medical detection device with multiple detection electrodes
US9135398B2 (en) 2011-03-25 2015-09-15 Zoll Medical Corporation System and method for adapting alarms in a wearable medical device
US9684767B2 (en) 2011-03-25 2017-06-20 Zoll Medical Corporation System and method for adapting alarms in a wearable medical device
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JP2015523877A (en) 2012-05-31 2015-08-20 ゾール メディカル コーポレイションＺＯＬＬ Ｍｅｄｉｃａｌ Ｃｏｒｐｏｒａｔｉｏｎ System and method for detecting health disorders
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WO2016100906A1 (en) 2014-12-18 2016-06-23 Zoll Medical Corporation Pacing device with acoustic sensor
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WO2016208152A1 (en) * 2015-06-25 2016-12-29 パナソニックＩｐマネジメント株式会社 Cardiac potential detection device and cardiac potential detection method
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Also Published As

Publication number Publication date
EP2375973A2 (en) 2011-10-19
CA2747057A1 (en) 2010-07-08
EP2375973A4 (en) 2014-02-12
WO2010077997A2 (en) 2010-07-08

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