WO2010048337A3 - Preservation of information related to genomic dna methylation - Google Patents

Preservation of information related to genomic dna methylation Download PDF

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Publication number
WO2010048337A3
WO2010048337A3 PCT/US2009/061552 US2009061552W WO2010048337A3 WO 2010048337 A3 WO2010048337 A3 WO 2010048337A3 US 2009061552 W US2009061552 W US 2009061552W WO 2010048337 A3 WO2010048337 A3 WO 2010048337A3
Authority
WO
WIPO (PCT)
Prior art keywords
preservation
information related
genomic dna
dna methylation
analyzing
Prior art date
Application number
PCT/US2009/061552
Other languages
French (fr)
Other versions
WO2010048337A2 (en
Inventor
Henri A. Kester
Original Assignee
Illumina, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42119966&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2010048337(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Illumina, Inc. filed Critical Illumina, Inc.
Priority to US13/125,419 priority Critical patent/US8541207B2/en
Priority to EP09822662.4A priority patent/EP2340314B8/en
Publication of WO2010048337A2 publication Critical patent/WO2010048337A2/en
Publication of WO2010048337A3 publication Critical patent/WO2010048337A3/en
Priority to US14/020,241 priority patent/US8895268B2/en
Priority to US14/327,892 priority patent/US9605311B2/en
Priority to US15/469,811 priority patent/US10174372B2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6874Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855Ligating adaptors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Abstract

The present invention relates to compositions, methods and systems for analyzing the methylation state of nucleic acids. Some embodiments relate to a compositions, methods and systems for analyzing the methylation state of DNA with a gene array.
PCT/US2009/061552 2008-10-22 2009-10-21 Preservation of information related to genomic dna methylation WO2010048337A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US13/125,419 US8541207B2 (en) 2008-10-22 2009-10-21 Preservation of information related to genomic DNA methylation
EP09822662.4A EP2340314B8 (en) 2008-10-22 2009-10-21 Preservation of information related to genomic dna methylation
US14/020,241 US8895268B2 (en) 2008-10-22 2013-09-06 Preservation of information related to genomic DNA methylation
US14/327,892 US9605311B2 (en) 2008-10-22 2014-07-10 Tandem sequencing top and bottom strands of double stranded nucleic acid using arrays configured for single molecule detection
US15/469,811 US10174372B2 (en) 2008-10-22 2017-03-27 Preservation of information related to genomic DNA methylation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10745708P 2008-10-22 2008-10-22
US61/107,457 2008-10-22

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US13/125,419 A-371-Of-International US8541207B2 (en) 2008-10-22 2009-10-21 Preservation of information related to genomic DNA methylation
US14/020,241 Division US8895268B2 (en) 2008-10-22 2013-09-06 Preservation of information related to genomic DNA methylation

Publications (2)

Publication Number Publication Date
WO2010048337A2 WO2010048337A2 (en) 2010-04-29
WO2010048337A3 true WO2010048337A3 (en) 2010-09-30

Family

ID=42119966

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/061552 WO2010048337A2 (en) 2008-10-22 2009-10-21 Preservation of information related to genomic dna methylation

Country Status (3)

Country Link
US (4) US8541207B2 (en)
EP (1) EP2340314B8 (en)
WO (1) WO2010048337A2 (en)

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US9175338B2 (en) 2008-12-11 2015-11-03 Pacific Biosciences Of California, Inc. Methods for identifying nucleic acid modifications
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US9238836B2 (en) 2012-03-30 2016-01-19 Pacific Biosciences Of California, Inc. Methods and compositions for sequencing modified nucleic acids
US9175348B2 (en) 2012-04-24 2015-11-03 Pacific Biosciences Of California, Inc. Identification of 5-methyl-C in nucleic acid templates
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Also Published As

Publication number Publication date
US10174372B2 (en) 2019-01-08
EP2340314B1 (en) 2014-10-01
EP2340314B8 (en) 2015-02-18
WO2010048337A2 (en) 2010-04-29
US8541207B2 (en) 2013-09-24
US9605311B2 (en) 2017-03-28
US20150011408A1 (en) 2015-01-08
US20110201524A1 (en) 2011-08-18
US8895268B2 (en) 2014-11-25
EP2340314A2 (en) 2011-07-06
EP2340314A4 (en) 2012-06-20
US20170260581A1 (en) 2017-09-14
US20140038851A1 (en) 2014-02-06

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